ATE135346T1 - Dideoxy-l-arabinitol derivate als antivirus- verbindungen - Google Patents
Dideoxy-l-arabinitol derivate als antivirus- verbindungenInfo
- Publication number
- ATE135346T1 ATE135346T1 AT89870169T AT89870169T ATE135346T1 AT E135346 T1 ATE135346 T1 AT E135346T1 AT 89870169 T AT89870169 T AT 89870169T AT 89870169 T AT89870169 T AT 89870169T AT E135346 T1 ATE135346 T1 AT E135346T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- antivirus
- dideoxy
- arabinitol
- derivatives
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000002155 anti-virotic effect Effects 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/164—Unsaturated ethers containing six-membered aromatic rings
- C07C43/166—Unsaturated ethers containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/40—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with ozone; by ozonolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/266,718 US4876268A (en) | 1988-11-03 | 1988-11-03 | Antiviral compounds and use thereof |
| US07/410,640 US4973602A (en) | 1988-11-03 | 1989-09-26 | Antiviral compounds and a method of use thereas |
| US07/410,638 US4937357A (en) | 1988-11-03 | 1989-09-26 | Intermediates for antiviral compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE135346T1 true ATE135346T1 (de) | 1996-03-15 |
Family
ID=27401904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89870169T ATE135346T1 (de) | 1988-11-03 | 1989-10-31 | Dideoxy-l-arabinitol derivate als antivirus- verbindungen |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0367747B1 (de) |
| JP (1) | JP2840334B2 (de) |
| AT (1) | ATE135346T1 (de) |
| CA (1) | CA2002105C (de) |
| DE (1) | DE68925940T2 (de) |
| ES (1) | ES2086323T3 (de) |
| GR (1) | GR3019885T3 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL124109A (en) * | 1995-09-08 | 2001-10-31 | Novo Nordisk As | Pharmaceutical composition of 2-alkylpyrrolidines for use in the manufacture of medicaments for the treatment of diabetes |
| AU761748B2 (en) | 1997-12-11 | 2003-06-12 | Chancellor, Masters And Scholars Of The University Of Oxford, The | Inhibition of membrane-associated viral replication |
| HK1046869A1 (zh) * | 1999-08-10 | 2003-01-30 | The Chancellor, Masters And Scholars Of The University Of Oxford | 使用长链n烷基化合物及其恶衍生物作为抗病毒成分 |
| CA2652958C (en) * | 2006-05-24 | 2015-11-17 | United Therapeutics Corporation | Deoxynojirimycin and d-arabinitol analogs and methods of using |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4999360A (en) * | 1987-12-21 | 1991-03-12 | Monsanto Company | Method of inhibiting virus |
-
1989
- 1989-10-31 ES ES89870169T patent/ES2086323T3/es not_active Expired - Lifetime
- 1989-10-31 AT AT89870169T patent/ATE135346T1/de not_active IP Right Cessation
- 1989-10-31 DE DE68925940T patent/DE68925940T2/de not_active Expired - Fee Related
- 1989-10-31 EP EP89870169A patent/EP0367747B1/de not_active Expired - Lifetime
- 1989-11-02 CA CA002002105A patent/CA2002105C/en not_active Expired - Fee Related
- 1989-11-02 JP JP1287315A patent/JP2840334B2/ja not_active Expired - Fee Related
-
1996
- 1996-05-10 GR GR960401265T patent/GR3019885T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0367747A3 (de) | 1991-05-08 |
| GR3019885T3 (en) | 1996-08-31 |
| JP2840334B2 (ja) | 1998-12-24 |
| JPH02172972A (ja) | 1990-07-04 |
| ES2086323T3 (es) | 1996-07-01 |
| DE68925940D1 (de) | 1996-04-18 |
| CA2002105A1 (en) | 1990-05-03 |
| EP0367747B1 (de) | 1996-03-13 |
| DE68925940T2 (de) | 1996-10-24 |
| CA2002105C (en) | 1999-01-19 |
| EP0367747A2 (de) | 1990-05-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |