ATE135372T1 - Verfahren zum nachweis von glucagon-antagonisten - Google Patents

Verfahren zum nachweis von glucagon-antagonisten

Info

Publication number: ATE135372T1
Authority: AT; Austria
Prior art keywords: glucagon; response pathway; stimulation; analogs; glucagon antagonists
Prior art date: 1991-01-17

Application number

AT92904367T

Other languages

English (en)

Inventor

Robert A Smith

James R Piggott

Original Assignee

Zymogenetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-17

Filing date

1992-01-14

Publication date

1996-03-15

1991-08-08 Priority claimed from US07/741,931 external-priority patent/US5408037A/en

1992-01-14 Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc

1996-03-15 Application granted granted Critical

1996-03-15 Publication of ATE135372T1 publication Critical patent/ATE135372T1/de

Links

MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 title abstract 8
102000051325 Glucagon Human genes 0.000 title abstract 6
108060003199 Glucagon Proteins 0.000 title abstract 6
229960004666 glucagon Drugs 0.000 title abstract 6
239000005557 antagonist Substances 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 4
230000037361 pathway Effects 0.000 abstract 3
108010063919 Glucagon Receptors Proteins 0.000 abstract 2
102100040890 Glucagon receptor Human genes 0.000 abstract 2
230000000638 stimulation Effects 0.000 abstract 2
108020004511 Recombinant DNA Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

AT92904367T 1991-01-17 1992-01-14 Verfahren zum nachweis von glucagon-antagonisten ATE135372T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US64134391A	1991-01-17	1991-01-17
US07/741,931 US5408037A (en)	1991-01-17	1991-08-08	Methods for detecting glucagon antagonists

Publications (1)

Publication Number	Publication Date
ATE135372T1 true ATE135372T1 (de)	1996-03-15

Family

ID=24571964

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92904367T ATE135372T1 (de)	1991-01-17	1992-01-14	Verfahren zum nachweis von glucagon-antagonisten

Country Status (10)

Country	Link
EP (1)	EP0567562B1 (de)
JP (1)	JPH06504913A (de)
AT (1)	ATE135372T1 (de)
AU (2)	AU663861B2 (de)
CA (1)	CA2100874A1 (de)
DE (1)	DE69209052T2 (de)
DK (1)	DK0567562T3 (de)
ES (1)	ES2085004T3 (de)
GR (1)	GR3019673T3 (de)
WO (1)	WO1992012998A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8497391A (en) *	1990-08-31	1992-03-30	Rockefeller University, The	Glucagon analogs with asp9 replacements or deletions
US5510459A (en) *	1991-01-17	1996-04-23	Zymogenetics, Inc.	Glucagon antagonists
US5408037A (en) *	1991-01-17	1995-04-18	Zymogenetics, Inc.	Methods for detecting glucagon antagonists
US5776725A (en) *	1992-08-28	1998-07-07	Zymogenetics, Inc.	Recombinant production of glucagon receptors
ATE285472T1 (de) *	1992-08-28	2005-01-15	Novo Nordisk As	Glucagonrezeptoren
US5480867A (en) *	1993-12-29	1996-01-02	The Rockefeller University	Glucagon analogs with serine replacements
AR036711A1 (es) *	2001-10-05	2004-09-29	Bayer Corp	Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacologico
BRPI0915282A2 (pt) *	2008-06-17	2017-02-07	Univ Indiana Res & Tech Corp	agonistas mistos baseados no gip para o tratamento de distúrbios metabólicos e obesidade

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4879273A (en) *	1987-05-22	1989-11-07	The Rockefeller University	Glucagon homologs and therapeutic use thereof
CA2345497A1 (en) *	1988-10-28	1990-04-28	Genentech, Inc.	Growth hormone variants and method for forming growth hormone variants

1992
- 1992-01-14 AT AT92904367T patent/ATE135372T1/de not_active IP Right Cessation
- 1992-01-14 CA CA002100874A patent/CA2100874A1/en not_active Abandoned
- 1992-01-14 ES ES92904367T patent/ES2085004T3/es not_active Expired - Lifetime
- 1992-01-14 DK DK92904367.7T patent/DK0567562T3/da active
- 1992-01-14 WO PCT/US1992/000346 patent/WO1992012998A1/en not_active Ceased
- 1992-01-14 DE DE69209052T patent/DE69209052T2/de not_active Expired - Fee Related
- 1992-01-14 EP EP92904367A patent/EP0567562B1/de not_active Expired - Lifetime
- 1992-01-14 JP JP4504578A patent/JPH06504913A/ja active Pending
- 1992-01-14 AU AU12003/92A patent/AU663861B2/en not_active Ceased
1995
- 1995-09-06 AU AU30475/95A patent/AU673648B2/en not_active Ceased
1996
- 1996-04-19 GR GR960401050T patent/GR3019673T3/el unknown

Also Published As

Publication number	Publication date
AU673648B2 (en)	1996-11-14
AU663861B2 (en)	1995-10-26
JPH06504913A (ja)	1994-06-09
EP0567562A1 (de)	1993-11-03
ES2085004T3 (es)	1996-05-16
AU1200392A (en)	1992-08-27
WO1992012998A1 (en)	1992-08-06
AU3047595A (en)	1995-12-07
DK0567562T3 (da)	1996-07-29
DE69209052D1 (de)	1996-04-18
EP0567562B1 (de)	1996-03-13
DE69209052T2 (de)	1996-11-14
CA2100874A1 (en)	1992-07-18
GR3019673T3 (en)	1996-07-31

Similar Documents

Publication	Publication Date	Title
DE3883522D1 (de)	1993-09-30	Verfahren zum diagnostizieren von blutpfropfen mit fibrin-bindenden proteinen.
NO873522D0 (no)	1987-08-20	Apparat til bruk i energiutvinning.
DE68905633D1 (de)	1993-05-06	Markierer der t-zelle aktivierung.
IS5697A (is)	2000-10-31	Uppleysanlegur T-eitilfrumu viðtaki
DE69333726T8 (de)	2006-04-27	Glucagonrezeptoren
DE3684380D1 (de)	1992-04-23	Verfahren zum einebnen von halbleiteranordnungen.
DE3862384D1 (de)	1991-05-23	Schwenkbares standbrett zum ueben von golf.
DE3672059D1 (de)	1990-07-19	Verfahren zum komprimieren von zwei-pegeldaten.
DE69209052D1 (de)	1996-04-18	Verfahren zum nachweis von glucagon-antagonisten
DE3767747D1 (de)	1991-03-07	Verfahren zum bestimmen von abmessungen.
DE68906650D1 (de)	1993-06-24	Verfahren zur zementierung von plattformbeinen.
DE3883364D1 (de)	1993-09-23	Verfahren zum nachweis von potentiellen karzinogenen.
EP1514932A3 (de)	2008-03-05	Glucagonrezeptoren
DE68919906D1 (de)	1995-01-26	Verfahren zum Reinigen von Methyl-Methacrylat.
DE58901845D1 (de)	1992-08-20	Verfahren zum festlegen.
DE68904369D1 (de)	1993-02-25	Verfahren und vorrichtung zum befestigen von landungsbruecken auf pfaehlen.
DK0862627T3 (da)	2004-11-29	Neuropeptid Y-Y5 receptor
FI885868A7 (fi)	1988-12-19	Menetelmä immuunikatoviruksen vasta-aineiden havaitsemiseksi
DE69203441D1 (de)	1995-08-17	Verfahren zum wälzschleifen von kronrädern.
DE69209305D1 (de)	1996-04-25	Verfahren zum verbinden von kohlebauteilen
DE69213824D1 (de)	1996-10-24	DNS-Sonden zum Nachweis von Eimeria necatrix
DE3873884D1 (de)	1992-09-24	Geraet zum schachtabteufen.
DE3862523D1 (de)	1991-05-29	Apparat zum stapeln von furnierblaettern.
DE3868187D1 (de)	1992-03-12	Verfahren zum hydroformylieren von bestimmten acrylsaeurederivaten.
ATA107689A (de)	1994-09-15	An gebäudegerüsten anbringbare vorrichtung zum auftragen von massen, insbesondere klebemassen

Legal Events

Date	Code	Title	Description
1996-11-15	UEP	Publication of translation of european patent specification
1998-10-15	REN	Ceased due to non-payment of the annual fee