ATE135689T1 - 1,2,3,6-tetrahydronpyridinderivate - Google Patents
1,2,3,6-tetrahydronpyridinderivateInfo
- Publication number
- ATE135689T1 ATE135689T1 AT91311257T AT91311257T ATE135689T1 AT E135689 T1 ATE135689 T1 AT E135689T1 AT 91311257 T AT91311257 T AT 91311257T AT 91311257 T AT91311257 T AT 91311257T AT E135689 T1 ATE135689 T1 AT E135689T1
- Authority
- AT
- Austria
- Prior art keywords
- general formula
- stands
- tetrahydropyridine
- chem
- hydrogen
- Prior art date
Links
- 150000008083 1,2,3,6-tetrahydropyridines Chemical class 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000141 anti-hypoxic effect Effects 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Luminescent Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU908253A HU209573B (en) | 1990-12-13 | 1990-12-13 | Process for producing of 1,2,3,6-tetrahydropyridine derivatives and pharmaceutical compositions comprising these substances |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE135689T1 true ATE135689T1 (de) | 1996-04-15 |
Family
ID=10972493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91311257T ATE135689T1 (de) | 1990-12-13 | 1991-12-03 | 1,2,3,6-tetrahydronpyridinderivate |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5225416A (de) |
| EP (1) | EP0490560B1 (de) |
| JP (1) | JPH04275272A (de) |
| KR (1) | KR920012033A (de) |
| AT (1) | ATE135689T1 (de) |
| AU (1) | AU647704B2 (de) |
| CA (1) | CA2056582A1 (de) |
| DE (1) | DE69118129T2 (de) |
| HU (1) | HU209573B (de) |
| IL (1) | IL100098A (de) |
| ZA (1) | ZA919338B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU211019B (en) * | 1991-12-02 | 1995-09-28 | Richter Gedeon Vegyeszet | Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds |
| WO2014140671A1 (en) | 2013-03-15 | 2014-09-18 | Institut De Recherche Pour Le Developpement | New arylaminoalcohol derivatives with antiplasmodial activity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB948071A (en) * | 1959-05-01 | 1964-01-29 | May & Baker Ltd | New heterocyclic compounds |
| GB984364A (en) * | 1961-07-28 | 1965-02-24 | May & Baker Ltd | Substituted piperidines and tetrahydropyridines |
| US3426036A (en) * | 1966-08-04 | 1969-02-04 | Aldrich Chem Co Inc | N - (p - phenoxybenzoyl - lower alkyl)-4-phenyl-tetrahydropyridyl derivatives; the corresponding alcohol,carbamate and lower alkylene derivatives |
| EP0004727B1 (de) * | 1978-04-12 | 1981-08-12 | Imperial Chemical Industries Plc | Pyridinderivate, die die Aggregation von Blutplättchen hemmen, diese Derivate enthaltende pharmazeutische Zusammensetzungen und Verfahren zu ihrer Herstellung |
-
1990
- 1990-12-13 HU HU908253A patent/HU209573B/hu not_active IP Right Cessation
-
1991
- 1991-11-20 IL IL10009891A patent/IL100098A/en not_active IP Right Cessation
- 1991-11-26 ZA ZA919338A patent/ZA919338B/xx unknown
- 1991-11-28 CA CA002056582A patent/CA2056582A1/en not_active Abandoned
- 1991-12-03 AT AT91311257T patent/ATE135689T1/de active
- 1991-12-03 DE DE69118129T patent/DE69118129T2/de not_active Expired - Fee Related
- 1991-12-03 EP EP91311257A patent/EP0490560B1/de not_active Expired - Lifetime
- 1991-12-10 KR KR1019910022511A patent/KR920012033A/ko not_active Withdrawn
- 1991-12-10 US US07/805,861 patent/US5225416A/en not_active Expired - Fee Related
- 1991-12-12 AU AU89620/91A patent/AU647704B2/en not_active Ceased
- 1991-12-12 JP JP3328973A patent/JPH04275272A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69118129T2 (de) | 1996-07-25 |
| AU8962091A (en) | 1992-06-18 |
| CA2056582A1 (en) | 1992-06-14 |
| EP0490560B1 (de) | 1996-03-20 |
| US5225416A (en) | 1993-07-06 |
| KR920012033A (ko) | 1992-07-25 |
| IL100098A0 (en) | 1992-08-18 |
| AU647704B2 (en) | 1994-03-24 |
| DE69118129D1 (de) | 1996-04-25 |
| HU209573B (en) | 1994-08-29 |
| IL100098A (en) | 1995-07-31 |
| HUT62269A (en) | 1993-04-28 |
| HU908253D0 (en) | 1991-06-28 |
| JPH04275272A (ja) | 1992-09-30 |
| ZA919338B (en) | 1992-09-30 |
| EP0490560A1 (de) | 1992-06-17 |
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