ATE137669T1 - Festes eingekapseltes arzneimittel, verfahren und vorrichtung zu seiner herstellung - Google Patents

Festes eingekapseltes arzneimittel, verfahren und vorrichtung zu seiner herstellung

Info

Publication number
ATE137669T1
ATE137669T1 AT89121229T AT89121229T ATE137669T1 AT E137669 T1 ATE137669 T1 AT E137669T1 AT 89121229 T AT89121229 T AT 89121229T AT 89121229 T AT89121229 T AT 89121229T AT E137669 T1 ATE137669 T1 AT E137669T1
Authority
AT
Austria
Prior art keywords
capsule
solid
encapsuled
production
medicinal product
Prior art date
Application number
AT89121229T
Other languages
English (en)
Inventor
Dean M Graham
Original Assignee
D M Graham Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D M Graham Lab Inc filed Critical D M Graham Lab Inc
Application granted granted Critical
Publication of ATE137669T1 publication Critical patent/ATE137669T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00—General characteristics or adaptations
    • A61J2200/20—Extrusion means, e.g. for producing pharmaceutical forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S53/00—Package making
    • Y10S53/90—Capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
AT89121229T 1988-11-17 1989-11-16 Festes eingekapseltes arzneimittel, verfahren und vorrichtung zu seiner herstellung ATE137669T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/272,734 US4936074A (en) 1988-11-17 1988-11-17 Process for preparing solid encapsulated medicament

Publications (1)

Publication Number Publication Date
ATE137669T1 true ATE137669T1 (de) 1996-05-15

Family

ID=23041048

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89121229T ATE137669T1 (de) 1988-11-17 1989-11-16 Festes eingekapseltes arzneimittel, verfahren und vorrichtung zu seiner herstellung

Country Status (9)

Country Link
US (2) US4936074A (de)
EP (1) EP0369445B1 (de)
JP (1) JPH02231420A (de)
AT (1) ATE137669T1 (de)
AU (1) AU632770B2 (de)
CA (1) CA2002945C (de)
DE (1) DE68926432T2 (de)
ES (1) ES2086311T3 (de)
GR (1) GR3020003T3 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4936074A (en) * 1988-11-17 1990-06-26 D. M. Graham Laboratories, Inc. Process for preparing solid encapsulated medicament
US5051132A (en) * 1989-06-15 1991-09-24 Nippon Kayaku Kabushiki Kaisha Lyophilized preparation of 6-(3-dimethylaminopropionyl)forskolin
US5456919A (en) * 1989-12-29 1995-10-10 Bristol-Myers Squibb Company Capsule and caplet combination
US5464631A (en) * 1990-06-27 1995-11-07 Warner-Lambert Company Encapsulated dosage forms
US5460824A (en) * 1990-06-27 1995-10-24 Warner-Lambert Company Method for the preparation of an encapsulated medicament
DE4133831A1 (de) * 1991-09-14 1993-03-18 Draegerwerk Ag Elektrochemische messzelle zum nachweis und zur bestimmung von gasen und daempfen insbesondere von halogen-wasserstoffen
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
US5317849A (en) * 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
US5415868A (en) * 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
US5458888A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US6245350B1 (en) 1994-12-16 2001-06-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
CA2205553C (en) * 1994-12-16 2009-04-07 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
US5660859A (en) * 1994-12-29 1997-08-26 Mcneil-Ppc, Inc. Gelling agent for polyethylene glycol
NZ280610A (en) * 1994-12-29 1997-08-22 Mcneil Ppc Inc Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent
US5919481A (en) * 1996-06-28 1999-07-06 Ncneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form
US6139872A (en) * 1996-08-14 2000-10-31 Henkel Corporation Method of producing a vitamin product
PT1121103E (pt) 1998-05-18 2007-02-28 Takeda Pharmaceutical Comprimidos de desintegração oral compreendendo um benzimidazole
AT407111B (de) 1998-12-22 2000-12-27 Gergely Dr & Co Zucker- und/oder zuckeralkoholhältiges matrixmaterial und verfahren zu seiner herstellung
DE19930030B4 (de) * 1999-06-30 2004-02-19 Meduna Arzneimittel Gmbh CO-3-ungesättigte Fettsäuren enthaltende orale Darreichungsform
IL147826A0 (en) * 1999-07-30 2002-08-14 Smithkline Beecham Plc Multi-component pharmaceutical dosage form
US7264824B1 (en) 2000-04-13 2007-09-04 Meduna Arzneimittel Gmbh Oral dosage form
GB0027954D0 (en) * 2000-11-16 2001-01-03 Mw Encap Ltd Liquid filled capsules
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
US20040081689A1 (en) * 2002-10-24 2004-04-29 Dunfield John Stephen Pharmaceutical dosage form and method of making
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
TW200539903A (en) * 2004-03-12 2005-12-16 Smithkline Beecham Plc Pharmaceutical formulations
US7867548B2 (en) 2006-10-27 2011-01-11 Hewlett-Packard Development Company, L.P. Thermal ejection of solution having solute onto device medium
DE102007023399A1 (de) * 2007-05-22 2008-11-27 Robert Bosch Gmbh Kapsel zur Aufnahme eines Mediums sowie Verfahren zur Herstellung einer derartigen Kapsel
JPWO2008146686A1 (ja) * 2007-05-25 2010-08-19 ベックマン・コールター・インコーポレーテッド 酵素含有カプセル及び核酸の増幅キット
JP2012502883A (ja) * 2008-06-13 2012-02-02 グラクソ グループ リミテッド 医薬製剤
US8371092B1 (en) * 2008-09-05 2013-02-12 Viropharma Incorporated Apparatus and methods for reducing capsule elongation
ES2956840T3 (es) * 2013-08-19 2023-12-29 Taris Biomedical Llc Dispositivos de administración de fármacos de múltiples unidades
EP4480495A3 (de) * 2017-07-10 2025-06-18 Gel Cap Technologies, LLC Kapsel mit dualer freisetzung und verfahren, vorrichtungen und systeme zu ihrer herstellung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297357A (de) * 1962-08-31
DE1933562A1 (de) * 1969-07-02 1971-01-14 Ct De Rech S Marcel Midy Verfahren und Vorrichtung zum Abpacken von Substanzen
US4028024A (en) * 1974-10-31 1977-06-07 Moreland Stephen T Manufacture of filled capsules or the like
US4163354A (en) * 1978-03-22 1979-08-07 Austin Leonard H Method and apparatus for filling capsules
US4349529A (en) * 1980-04-14 1982-09-14 E. R. Squibb & Sons, Inc. Diagnostic and therapeutic capsules and method of producing
DE3022136C2 (de) * 1980-06-13 1986-07-17 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zum Abfüllen von Phospholipide enthaltenden pharmazeutischen Massen in Hartkapseln
GB2118040A (en) * 1982-02-15 1983-10-26 Hoechst Uk Ltd Oral anti-diabetic preparation
US4655840A (en) * 1982-03-26 1987-04-07 Warner-Lambert Company Hydrophilic polymer compositions for injection molding
EG16028A (en) * 1982-03-26 1986-12-30 Warner Lambert Co Apparatus and method for molding capsules
US4673438A (en) * 1984-02-13 1987-06-16 Warner-Lambert Company Polymer composition for injection molding
US4928840A (en) * 1986-02-25 1990-05-29 American Home Products Corporation Tamper proof encapsulated medicaments
US4734149A (en) * 1987-03-20 1988-03-29 Warner-Lambert Company Apparatus for heatsealing gelatin capsules containing a medicament
US4936074A (en) * 1988-11-17 1990-06-26 D. M. Graham Laboratories, Inc. Process for preparing solid encapsulated medicament

Also Published As

Publication number Publication date
CA2002945A1 (en) 1990-05-17
EP0369445B1 (de) 1996-05-08
ES2086311T3 (es) 1996-07-01
EP0369445A3 (de) 1991-06-05
GR3020003T3 (en) 1996-08-31
DE68926432D1 (de) 1996-06-13
AU632770B2 (en) 1993-01-14
US4936074A (en) 1990-06-26
CA2002945C (en) 1996-07-23
EP0369445A2 (de) 1990-05-23
JPH02231420A (ja) 1990-09-13
DE68926432T2 (de) 1996-09-26
US5085033A (en) 1992-02-04
AU4465989A (en) 1990-05-24

Similar Documents

Publication Publication Date Title
DE68926432D1 (de) Festes eingekapseltes Arzneimittel, Verfahren und Vorrichtung zu seiner Herstellung
DE59209907D1 (de) Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
DE69425932D1 (de) Schnellauflösliche pharmazeutische Dosierungsformen und Verfahren zu ihrer Herstellung
AU5150490A (en) Methods of preserving products and novel compositions therefor
HUT70157A (en) Imidazolylalcenoic acids, pharmaceutical compositions containing them, and process for producing them, and use of them for preparing medicaments
UA43343C2 (uk) Магнієва сіль омепразолу, спосіб її одержання, фармацевтична композиція, спосіб лікування
IE861813L (en) New Polysaccharide Esters and their Salts
DE4002532A1 (de) Hautkosmetika
YU46701B (sh) Postupak u za dobijanje osnovnog nosećeg materijala za dozne oblike lekova sa produženim izdvajanjem aktivne supstance
HUT55403A (en) Process for producing modified gangliosides and their functional derivatives, as well as pharmaceutical compositions comprising such active ingredient
DE3780056D1 (de) Verfahren zur herstellung von arzneimittelformulierungen mit gesteuerter und verlaengerter wirkung in einzeldosisform mit einheitlichen und vergleichbaren bioverfuegbarkeitscharakteristika.
FI943604A0 (fi) Menetelmä suklaan muotosäilyvyyden parantamiseksi
HU9303749D0 (en) 2,4-substituted 5-(n-substituted-sulfamoyl)-benzoyl-guanidines, process for producing them, their use as medicine or diagnosticum and pharmaceutical compositions containing them
DE3767998D1 (de) Clodronat-haltige arzneimittel und verfahren zur herstellung derselben.
DE725570T1 (de) Zusammensetzung und system zur oralen verabreichung an tiere
DE69101490D1 (de) Verfahren zum Einbauen in Pellets von gegen Abbau im Pansen von Wiederkäuern geschützten Wirkstoffen.
AT382076B (de) Verfahren zur herstellung von presslingen mit retardierter wirkstofffreisetzung
DE19536387A1 (de) Verfahren zur Herstellung von vitaminhaltigen festen Zubereitungen
HUT69372A (en) Diamine salts of clarulanic acid, pharmaceutical compositions containing the same and process for their production
DE59002265D1 (de) Kaugummi zur mund- und rachendesinfektion, sowie verfahren zu seiner herstellung.
HUT59116A (en) Process for producing oxazole derivatives and pharmaceutical compositions comprising oxazole derivatives as active ingredient
ATE353321T1 (de) Dreiringige verbindungen, verfahren zu ihrer herstellung und zwischenprodukte dieses verfahren,ihre anwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen
DE3809764A1 (de) Mischung aus alginaten und polyacrylaten und deren verwendung
ATE85213T1 (de) Einen wirkstoff und ein in wasser quellendes polymer enthaltendes arzneimittel.
WO2002034238A3 (en) Colored gelatin-based formulations and method

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee