ATE140697T1 - Verfahren zur herstellung von 4-substituierten azetidinonen - Google Patents
Verfahren zur herstellung von 4-substituierten azetidinonenInfo
- Publication number
- ATE140697T1 ATE140697T1 AT90310206T AT90310206T ATE140697T1 AT E140697 T1 ATE140697 T1 AT E140697T1 AT 90310206 T AT90310206 T AT 90310206T AT 90310206 T AT90310206 T AT 90310206T AT E140697 T1 ATE140697 T1 AT E140697T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- substituted azetidinones
- substituted
- azetidinones
- beta
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- -1 4,4-disubstituted azetidinones Chemical class 0.000 abstract 1
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical class O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/410,173 US4992545A (en) | 1989-09-20 | 1989-09-20 | Process for preparing 4-substituted azetidinones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE140697T1 true ATE140697T1 (de) | 1996-08-15 |
Family
ID=23623551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90310206T ATE140697T1 (de) | 1989-09-20 | 1990-09-18 | Verfahren zur herstellung von 4-substituierten azetidinonen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4992545A (de) |
| EP (1) | EP0419215B1 (de) |
| JP (1) | JPH03167170A (de) |
| KR (1) | KR910006228A (de) |
| AT (1) | ATE140697T1 (de) |
| CA (1) | CA2025517A1 (de) |
| DE (1) | DE69027900T2 (de) |
| DK (1) | DK0419215T3 (de) |
| ES (1) | ES2088979T3 (de) |
| GR (1) | GR3021309T3 (de) |
| HU (1) | HUT57188A (de) |
| IE (1) | IE74853B1 (de) |
| IL (1) | IL95714A (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5106475A (en) * | 1989-09-20 | 1992-04-21 | Eli Lilly And Company | Process for preparing 4-substituted azetidinones |
| US5089610A (en) * | 1991-04-25 | 1992-02-18 | Eli Lilly And Company | Ring-closure method for 1-carbacephalosporin six-membered ring |
| RO116087B1 (ro) * | 1992-09-18 | 2000-10-30 | Merck & Co Inc | Procedeu de preparare a 1-beta-metil carbapenemilor si intermediari in sinteza acestora |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7806860A (nl) * | 1977-07-05 | 1979-01-09 | Farmaceutici Italia | Werkwijze voor het bereiden van met nocardicine verwan- te azetidinonen. |
| US4368156A (en) * | 1981-03-09 | 1983-01-11 | Eli Lilly And Company | Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones |
| US4421686A (en) * | 1981-11-30 | 1983-12-20 | E. R. Squibb & Sons, Inc. | 4-Norbornyl-sulfonyl azetidinone intermediates and process for preparing (S)-3-acylamino-4-substituted-2-azetidinones |
| AU549269B2 (en) * | 1981-11-30 | 1986-01-23 | E.R. Squibb & Sons, Inc. | 3-acylamino-4-sulfonyl-2-azetidinones |
| HU190404B (en) * | 1982-07-30 | 1986-09-29 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing amino-lactone-carboxylic acid |
| US4652651A (en) * | 1983-05-31 | 1987-03-24 | Hoffmann-La Roche Inc. | Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage |
| DE3340006A1 (de) * | 1983-11-04 | 1985-05-23 | Hans Rudolf Prof. Dipl.-Chem. Dr. 8000 München Pfaendler | Verfahren zur herstellung von azetidin-2-onen |
| US4771135A (en) * | 1984-05-22 | 1988-09-13 | Eli Lilly And Company | Process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones and products and starting materials therefor |
| EP0163452A1 (de) * | 1984-05-22 | 1985-12-04 | Eli Lilly And Company | Verfahren zur Bildung einer Kohlenstoff-Kohlenstoff-Bindung an der C-4-Stellung von 3-Acylaminoazetidinonen |
| US4588484A (en) * | 1985-02-28 | 1986-05-13 | Eli Lilly And Company | Electrochemical reduction of 3-chlorobenzo[b]thiophenes |
| US4665171A (en) * | 1985-07-17 | 1987-05-12 | Harvard University | Process and intermediates for β-lactam antibiotics |
| US4960879A (en) * | 1988-03-23 | 1990-10-02 | Shionogi & Co., Ltd. | Process for carbapenem intermediates |
-
1989
- 1989-09-20 US US07/410,173 patent/US4992545A/en not_active Expired - Fee Related
-
1990
- 1990-09-17 CA CA002025517A patent/CA2025517A1/en not_active Abandoned
- 1990-09-17 IL IL9571490A patent/IL95714A/en not_active IP Right Cessation
- 1990-09-18 AT AT90310206T patent/ATE140697T1/de active
- 1990-09-18 DE DE69027900T patent/DE69027900T2/de not_active Expired - Fee Related
- 1990-09-18 DK DK90310206.9T patent/DK0419215T3/da active
- 1990-09-18 ES ES90310206T patent/ES2088979T3/es not_active Expired - Lifetime
- 1990-09-18 EP EP90310206A patent/EP0419215B1/de not_active Expired - Lifetime
- 1990-09-18 KR KR1019900014738A patent/KR910006228A/ko not_active Ceased
- 1990-09-19 IE IE339290A patent/IE74853B1/en not_active IP Right Cessation
- 1990-09-19 HU HU905971A patent/HUT57188A/hu unknown
- 1990-09-19 JP JP2251656A patent/JPH03167170A/ja active Pending
-
1996
- 1996-10-09 GR GR960402681T patent/GR3021309T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2025517A1 (en) | 1991-03-21 |
| DK0419215T3 (da) | 1996-08-26 |
| DE69027900T2 (de) | 1997-01-02 |
| IL95714A0 (en) | 1991-06-30 |
| DE69027900D1 (de) | 1996-08-29 |
| EP0419215B1 (de) | 1996-07-24 |
| KR910006228A (ko) | 1991-04-27 |
| HU905971D0 (en) | 1991-03-28 |
| EP0419215A2 (de) | 1991-03-27 |
| US4992545A (en) | 1991-02-12 |
| JPH03167170A (ja) | 1991-07-19 |
| HUT57188A (en) | 1991-11-28 |
| IE903392A1 (en) | 1991-04-10 |
| ES2088979T3 (es) | 1996-10-01 |
| IL95714A (en) | 1994-07-31 |
| IE74853B1 (en) | 1997-08-13 |
| EP0419215A3 (en) | 1992-04-08 |
| GR3021309T3 (en) | 1997-01-31 |
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