ATE141058T1 - Bilderzeugungsmittel für diagnose - Google Patents

Bilderzeugungsmittel für diagnose

Info

Publication number
ATE141058T1
ATE141058T1 AT92116804T AT92116804T ATE141058T1 AT E141058 T1 ATE141058 T1 AT E141058T1 AT 92116804 T AT92116804 T AT 92116804T AT 92116804 T AT92116804 T AT 92116804T AT E141058 T1 ATE141058 T1 AT E141058T1
Authority
AT
Austria
Prior art keywords
diagnosis
imaging agents
bifunctional ligand
metal ion
coordinated
Prior art date
Application number
AT92116804T
Other languages
English (en)
Inventor
Yuji Nihon Medi-Phy Hashiguchi
Kumiko Iwai
Shigemi Seri
Susumu Kondo
Makoto Azuma
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17314374&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE141058(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Application granted granted Critical
Publication of ATE141058T1 publication Critical patent/ATE141058T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • A61K49/128—Linear polymers, e.g. dextran, inulin, PEG comprising multiple complex or complex-forming groups, being either part of the linear polymeric backbone or being pending groups covalently linked to the linear polymeric backbone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
    • A61K51/065—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules conjugates with carriers being macromolecules
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
AT92116804T 1991-10-04 1992-10-01 Bilderzeugungsmittel für diagnose ATE141058T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3258017A JP2894879B2 (ja) 1991-10-04 1991-10-04 診断用造影剤

Publications (1)

Publication Number Publication Date
ATE141058T1 true ATE141058T1 (de) 1996-08-15

Family

ID=17314374

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92116804T ATE141058T1 (de) 1991-10-04 1992-10-01 Bilderzeugungsmittel für diagnose

Country Status (9)

Country Link
US (3) US5271924A (de)
EP (1) EP0535668B1 (de)
JP (1) JP2894879B2 (de)
KR (1) KR100219004B1 (de)
AT (1) ATE141058T1 (de)
CA (1) CA2079493C (de)
DE (1) DE69212630T2 (de)
DK (1) DK0535668T3 (de)
ES (1) ES2093163T3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783171A (en) * 1989-06-16 1998-07-21 Neorx Corporation Radionuclide metal N2 S2 chelates substituted with glucose and biotin moieties
DE4115789A1 (de) * 1991-05-10 1992-11-12 Schering Ag Makrocyclische polymer-komplexbildner, deren komplexe, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
AU698176B2 (en) * 1993-07-28 1998-10-29 Cis Bio International Radiolabelled glucans
EP0709100A1 (de) * 1994-09-30 1996-05-01 Nihon Medi-Physics Co., Ltd. Kontrastmittel mit mehreren Detektionsgruppen pro Molekül
CA2160819A1 (en) * 1994-10-21 1996-04-22 Yuji Hashiguchi Diagnostic imaging agent
TW319763B (de) 1995-02-01 1997-11-11 Epix Medical Inc
US5762903A (en) * 1995-03-10 1998-06-09 Korea Atomic Energy Research Institute Radioactive chitosan complex for radiation therapy
US5702682A (en) * 1995-12-01 1997-12-30 Hercules Incorporated Methods for preparing radiopaque medical devices
DE19728954C1 (de) * 1997-06-30 1999-04-22 Schering Ag Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung
IL147854A0 (en) * 1999-07-29 2002-08-14 Epix Medical Inc Multimeric compounds, contrast agents containing the same and diagnostic methods utilizing the same
IL145723A0 (en) * 2000-10-11 2002-07-25 Nihon Mediphysics Co Ltd Process for producing an amide compound
US20030050452A1 (en) * 2000-12-26 2003-03-13 Yuji Hashiguchi Process for producing metal complex of aminooligosaccharide derivative
US20040143180A1 (en) * 2001-11-27 2004-07-22 Sheng-Ping Zhong Medical devices visible under magnetic resonance imaging
US20030100830A1 (en) 2001-11-27 2003-05-29 Sheng-Ping Zhong Implantable or insertable medical devices visible under magnetic resonance imaging
EP1466629A1 (de) * 2003-04-11 2004-10-13 BRACCO IMAGING S.p.A. Adducte zwischen NMR Vershibungsreagenzen und Substraten mit austauschbaren Protonen für die "CEST" Anwendung
US8620406B2 (en) * 2004-01-23 2013-12-31 Boston Scientific Scimed, Inc. Medical devices visible by magnetic resonance imaging
US7483732B2 (en) * 2004-04-15 2009-01-27 Boston Scientific Scimed, Inc. Magnetic resonance imaging of a medical device and proximate body tissue
AU2006204045B2 (en) * 2005-01-05 2010-10-14 Board Of Regents, The University Of Texas System Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications
CN100382847C (zh) * 2005-02-05 2008-04-23 四川大学 用于影像诊断的配合体化合物及制备方法和影像诊断用化合物及其制备中间体
US7778684B2 (en) * 2005-08-08 2010-08-17 Boston Scientific Scimed, Inc. MRI resonator system with stent implant
US20070239256A1 (en) * 2006-03-22 2007-10-11 Jan Weber Medical devices having electrical circuits with multilayer regions
JP2008266194A (ja) * 2007-04-19 2008-11-06 Hiroshi Tanaka 分子プローブの原料として有用な新規有機化合物
JP2011063572A (ja) * 2009-09-18 2011-03-31 Kyushu Univ 診断用造影剤
EP2663338B1 (de) * 2011-01-14 2024-03-06 Emory University Glukosebasierte oligosaccharide enthaltend ein positronenemittierendes radionuklid und deren verwendung in der bildgebung
DE102019004953B4 (de) * 2019-07-17 2021-10-28 Günther Zimmer Brems- und/oder Klemmvorrichtung mit einteiligem Spaltgehäuse und Sensormodul
WO2021189052A1 (en) * 2020-03-20 2021-09-23 Robert Taub Composition for radiation treatment of intracavitary or metastatic deposits of malignancy and method for treatment therewith
CN114965543B (zh) * 2022-06-13 2023-10-20 青岛科技大学 壳寡糖nmr波谱的归属及脱乙酰度相关指标的测定方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413849D0 (en) * 1984-05-31 1984-07-04 Amersham Int Plc Nmr contrast agents
SE465907B (sv) * 1984-11-01 1991-11-18 Nyegaard & Co As Diagnosticeringsmedel innehaallande en paramagnetisk metall
SE8501613D0 (sv) * 1985-04-01 1985-04-01 Bio Carb Ab Foreningar for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutisk behandling
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
AU6621586A (en) * 1985-11-18 1987-06-02 University Of Texas System, The Polychelating agents for image and spectral enhancement (and spectral shift)
US5141739A (en) * 1986-07-03 1992-08-25 Advanced Magnetics, Inc. Delivery of x-ray contrast agents using receptor mediated endocytosis
DE3701665A1 (de) * 1987-01-19 1988-07-28 Schering Ag Polymer-komplexe, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
US4952393A (en) * 1987-04-02 1990-08-28 The General Hospital Corporation Organ infarct imaging with technetium labelled glucarate
US5094950A (en) * 1988-06-07 1992-03-10 Nihon Medi-Physics Co., Ltd. Diethylenetriamine pentaacetic acid derivatives
CH679742A5 (de) * 1990-01-09 1992-04-15 Byk Gulden Lomberg Chem Fab
JPH04154729A (ja) * 1990-10-16 1992-05-27 Nippon Mejifuijitsukusu Kk 磁気共鳴造影剤
US5143716A (en) * 1991-02-01 1992-09-01 Unger Evan C Phosphorylated sugar alcohols, Mono- and Di-Saccharides as contrast agents for use in magnetic resonance imaging of the gastrointestinal region

Also Published As

Publication number Publication date
ES2093163T3 (es) 1996-12-16
US5422095A (en) 1995-06-06
JPH0597712A (ja) 1993-04-20
US5352431A (en) 1994-10-04
KR100219004B1 (ko) 1999-09-01
DE69212630T2 (de) 1997-01-23
CA2079493C (en) 2002-05-28
AU2619192A (en) 1993-04-08
EP0535668B1 (de) 1996-08-07
KR930007462A (ko) 1993-05-20
DE69212630D1 (de) 1996-09-12
CA2079493A1 (en) 1993-04-05
JP2894879B2 (ja) 1999-05-24
US5271924A (en) 1993-12-21
DK0535668T3 (da) 1996-09-02
AU650791B2 (en) 1994-06-30
EP0535668A1 (de) 1993-04-07

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee