ATE141059T1 - Bakteriostatikum für radiopharmazeutische mittel - Google Patents

Bakteriostatikum für radiopharmazeutische mittel

Info

Publication number: ATE141059T1
Authority: AT; Austria
Prior art keywords: bacteriostatic; radiopharmaceutical agents; polymyxin; radiopharmaceutical; agents
Prior art date: 1991-04-09

Application number

AT92303074T

Other languages

English (en)

Inventor

Richard J Flanagan

Daniel Tartaglia

Original Assignee

Merck Frosst Canada Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-09

Filing date

1992-04-07

Publication date

1996-08-15

1991-04-09 Priority claimed from US07/682,170 external-priority patent/US5093105A/en

1991-12-12 Priority claimed from US07/806,572 external-priority patent/US5227152A/en

1992-04-07 Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc

1996-08-15 Application granted granted Critical

1996-08-15 Publication of ATE141059T1 publication Critical patent/ATE141059T1/de

Links

239000012217 radiopharmaceutical Substances 0.000 title abstract 2
230000003385 bacteriostatic effect Effects 0.000 title 1
108010040201 Polymyxins Proteins 0.000 abstract 2
239000003963 antioxidant agent Substances 0.000 abstract 1
235000006708 antioxidants Nutrition 0.000 abstract 1
239000000022 bacteriostatic agent Substances 0.000 abstract 1
229960000686 benzalkonium chloride Drugs 0.000 abstract 1
229960001950 benzethonium chloride Drugs 0.000 abstract 1
UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 abstract 1
CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
229940121896 radiopharmaceutical Drugs 0.000 abstract 1
230000002799 radiopharmaceutical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Optics & Photonics (AREA)
Engineering & Computer Science (AREA)
Physics & Mathematics (AREA)
Dispersion Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Organic Chemistry (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Anti-Oxidant Or Stabilizer Compositions (AREA)

AT92303074T 1991-04-09 1992-04-07 Bakteriostatikum für radiopharmazeutische mittel ATE141059T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US07/682,170 US5093105A (en)	1991-04-09	1991-04-09	Radiopharmaceutical bacteriostats
US07/806,572 US5227152A (en)	1991-04-09	1991-12-12	Radiopharmaceutical bacteriostats
US07/841,281 US5306482A (en)	1991-04-09	1992-03-03	Radiopharmaceutical bacteriostats

Publications (1)

Publication Number	Publication Date
ATE141059T1 true ATE141059T1 (de)	1996-08-15

Family

ID=27418397

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92303074T ATE141059T1 (de)	1991-04-09	1992-04-07	Bakteriostatikum für radiopharmazeutische mittel

Country Status (7)

Country	Link
US (1)	US5306482A (de)
EP (1)	EP0508724B1 (de)
JP (1)	JPH0772144B2 (de)
AT (1)	ATE141059T1 (de)
CA (1)	CA2065462C (de)
DE (1)	DE69212613T2 (de)
IE (1)	IE76295B1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6027710A (en) *	1996-09-18	2000-02-22	Nihon Medi-Physiscs Co., Ltd.	Radiation-protecting agent
US6579469B1 (en)	1999-10-29	2003-06-17	Closure Medical Corporation	Cyanoacrylate solutions containing preservatives
GB0015242D0 (en)	2000-06-22	2000-08-16	Nycomed Amersham Plc	Stabiliser for radiopharmaceuticals
GB0031592D0 (en) *	2000-12-28	2001-02-07	Nycomed Amersham Plc	Stabilised radiopharmaceutical compositions
US7344702B2 (en)	2004-02-13	2008-03-18	Bristol-Myers Squibb Pharma Company	Contrast agents for myocardial perfusion imaging
EP1654005A4 (de) *	2003-07-24	2011-06-15	Bracco Imaging Spa	Stabile radiopharmazeutische zusammensetzungen und herstellungsverfahren
US7485283B2 (en) *	2004-04-28	2009-02-03	Lantheus Medical Imaging	Contrast agents for myocardial perfusion imaging
US20080193379A1 (en) *	2005-06-14	2008-08-14	Nihon Medi-Physics Co., Ltd.	Radioactive Diagnostic Imaging Agent
GB0514087D0 (en)	2005-07-11	2005-08-17	Ge Healthcare Ltd	Stabilised radiopharmaceutical compositions
EP1977769A1 (de) *	2007-04-04	2008-10-08	Atomic Energy Council - Institute of Nuclear Energy Research	Kit zur Herstellung eines radioaktiven Iod-Markers beinhaltend lyophilisiertes Meta-Iodobenzylguanidin (MIBG), Herstellungsverfahren dafür sowie Methode zur radioaktiven markierung des MIBG.
US20090105195A1 (en) *	2007-10-17	2009-04-23	O'brien Chris	Composition comprising microbicidal active ingredients
WO2009110984A2 (en) *	2008-02-29	2009-09-11	Lantheus Medical Imaging, Inc.	Contrast agents for applications including perfusion imaging
EP2419096B1 (de)	2009-04-15	2019-11-13	Lantheus Medical Imaging, Inc.	Stabilisierung von radiopharmazeutischen zusammensetzungen mit ascorbinsäure
CN102858752B (zh)	2010-02-08	2018-10-16	兰休斯医疗成像公司	用于合成显像剂和其中间体的方法和装置
AU2013203000B9 (en)	2012-08-10	2017-02-02	Lantheus Medical Imaging, Inc.	Compositions, methods, and systems for the synthesis and use of imaging agents
WO2017155937A1 (en)	2016-03-07	2017-09-14	Actinium Pharmaceuticals, Inc.	Stabilized radiolabeled anti-cd45 immunoglobulin compositions
AU2024305035A1 (en)	2023-06-16	2026-01-29	Progenics Pharmaceuticals, Inc	Improved synthesis of the prostate specific membrane antigen (psma) radiolabeled inhibitor [18f]dcfpyl

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2565057A (en) *	1946-12-21	1951-08-21	Burroughs Wellcome Co	Polymyxin antibiotic
US2595605A (en) *	1948-08-07	1952-05-06	American Cyanamid Co	Method of producing polymyxin
US2771397A (en) *	1950-03-03	1956-11-20	Robert G Benedict	Antibiotic and method for producing it by bacillus polymyxa
US3044934A (en) *	1960-05-19	1962-07-17	Burroughs Wellcome Co	Parenteral administration of methanesulphonate of polymyxin a, b or e
US3863004A (en) *	1972-03-20	1975-01-28	Mallinckrodt Chemical Works	Denatured macroprotein with divalent tin for tagging with technetium-99m and method of preparation
US3987157A (en) *	1974-08-29	1976-10-19	Union Carbide Corporation	Technetium 99-m labeled radio-diagnostic agents employing stannous tartrate and method of preparation
US4364920A (en) *	1975-04-30	1982-12-21	Medi-Physics, Inc.	Stable diagnostic reagents
EP0054920B1 (de) *	1980-12-19	1984-03-07	Nihon Medi-Physics Co., Ltd.	3-Aminomethylen-2,4-pentanedion-bis(thiosemicarbazone) und ihre Herstellung und Verwendung
EP0078642B1 (de) *	1981-10-30	1986-12-10	AMERSHAM INTERNATIONAL plc	Radiopharmazeutische Zubereitung auf Grund von Technetium-99m und Reagenz zur Herstellung derselben
GB2127689B (en) *	1982-10-05	1986-07-09	Sandoz Ltd	Calcitonin inhalation compositions
US4510125A (en) *	1982-12-08	1985-04-09	Mallinckrodt, Inc.	Process for making lyophilized radiographic imaging kit
JPS6064931A (ja) *	1983-09-17	1985-04-13	Nippon Mejifuijitsukusu Kk	テクネチウム−９９ｍ標識つきがん診断剤
JPS61194034A (ja) *	1985-02-25	1986-08-28	Teijin Ltd	経鼻投与用粉末状組成物
US4830847A (en) *	1985-06-28	1989-05-16	The Procter & Gamble Company	Diphosphonate-derivatized macromolecules
PH25422A (en) *	1987-09-11	1991-07-01	Syntex Inc	Preservative system for ophthalmics
JP2815615B2 (ja) *	1988-06-07	1998-10-27	日本メジフィジックス株式会社	ジエチレントリアミン五酢酸誘導体とその用途
US4880615A (en) *	1988-11-25	1989-11-14	Merck & Co., Inc.	Stabilized radiopharmaceutical compositions
JPH03153217A (ja) *	1989-11-10	1991-07-01	Casio Comput Co Ltd	Ｔｆｔパネルおよびその製造方法
US5093105A (en) *	1991-04-09	1992-03-03	Merck Frosst Canada, Inc.	Radiopharmaceutical bacteriostats

1992
- 1992-03-03 US US07/841,281 patent/US5306482A/en not_active Expired - Lifetime
- 1992-04-07 AT AT92303074T patent/ATE141059T1/de not_active IP Right Cessation
- 1992-04-07 EP EP92303074A patent/EP0508724B1/de not_active Expired - Lifetime
- 1992-04-07 CA CA002065462A patent/CA2065462C/en not_active Expired - Fee Related
- 1992-04-07 DE DE69212613T patent/DE69212613T2/de not_active Expired - Fee Related
- 1992-04-08 IE IE921125A patent/IE76295B1/en not_active IP Right Cessation
- 1992-04-09 JP JP4133069A patent/JPH0772144B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH0772144B2 (ja)	1995-08-02
IE76295B1 (en)	1997-10-08
DE69212613D1 (de)	1996-09-12
EP0508724B1 (de)	1996-08-07
EP0508724A1 (de)	1992-10-14
DE69212613T2 (de)	1997-03-06
US5306482A (en)	1994-04-26
JPH05271102A (ja)	1993-10-19
CA2065462A1 (en)	1992-10-10
CA2065462C (en)	2002-12-24
IE921125A1 (en)	1992-10-21

Legal Events

Date	Code	Title	Description
1997-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE141059T1 (de)	1996-08-15	Bakteriostatikum für radiopharmazeutische mittel
DE69423125D1 (de)	2000-04-06	Meteologischer Arbeitsplatz
IT9019537A0 (it)	1990-03-02	Agenti scivolanti
DE69324324D1 (de)	1999-05-12	Gleichstromstabilisator
DE69315205D1 (de)	1997-12-18	Bedienungsarbeitsplatz
ITMI911782A1 (it)	1992-12-28	Disposizione di azionamento
DE69105798D1 (de)	1995-01-26	Gleichstrommotoranordnung.
DE59108946D1 (de)	1998-04-09	Synergistische herbizide mittel
NO930161L (no)	1993-07-21	Seismisk broennkilde
KR910017972U (ko)	1991-11-28	연마조립체
DE69203169D1 (de)	1995-08-03	Konstantstromquelle.
NO905425D0 (no)	1990-12-17	Seismisk kilde.
DK1211250T3 (da)	2004-10-25	C10-Taxanderivater samt farmaceutiske præparater
FI925302A7 (fi)	1992-11-20	Spindeldrivanordning
DE69123374D1 (de)	1997-01-16	Roboter vom Direkt-Teach-In-Typ
FI930068A7 (fi)	1993-01-08	Venttiililäppäjärjestely
NO943974D0 (no)	1994-10-20	Seismisk kilde
ATA189391A (de)	1995-10-15	Selbstladewagen
EP0664779A4 (de)	1995-06-16	Antibiotische mittel.
DE69502703D1 (de)	1998-07-02	Pneumatischer bremskraftverstärker mit symmetrischem gehäuse
YU48719B (sh)	1999-07-28	Lizin so 6-hloro-5-fluoro-3-(2-tenoil)-2-oksindol-1-karboksamida
FI916012A7 (fi)	1992-06-25	Overheadprojektor.
FI930010A0 (fi)	1993-01-04	Madrass
KR930020888U (ko)	1993-10-15	조립가구용 신축지주
FR2703260B1 (fr)	1995-06-30	Labyrinthe coulissant.