ATE141093T1 - Polypeptid - Google Patents
PolypeptidInfo
- Publication number
- ATE141093T1 ATE141093T1 AT91116017T AT91116017T ATE141093T1 AT E141093 T1 ATE141093 T1 AT E141093T1 AT 91116017 T AT91116017 T AT 91116017T AT 91116017 T AT91116017 T AT 91116017T AT E141093 T1 ATE141093 T1 AT E141093T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptide
- amino acid
- acid sequence
- mutein
- asp
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 5
- 239000013612 plasmid Substances 0.000 abstract 2
- IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical compound NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 abstract 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 108010072041 arginyl-glycyl-aspartic acid Proteins 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25004690 | 1990-09-21 | ||
| JP3240131A JPH04368398A (ja) | 1991-06-17 | 1991-06-17 | ポリペプチド |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE141093T1 true ATE141093T1 (de) | 1996-08-15 |
Family
ID=26534592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91116017T ATE141093T1 (de) | 1990-09-21 | 1991-09-20 | Polypeptid |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0477791B1 (de) |
| AT (1) | ATE141093T1 (de) |
| DE (1) | DE69121227T2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06263650A (ja) * | 1991-12-02 | 1994-09-20 | Chiba Seifun Kk | Lpsを含む抗腫瘍剤及び動物用抗腫瘍剤 |
| AU6001094A (en) * | 1993-02-03 | 1994-08-29 | N.V. Innogenetics S.A. | Tnf-alpha muteins and a process for preparing them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4959314A (en) * | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| WO1988006625A2 (en) * | 1987-02-26 | 1988-09-07 | Cetus Corporation | Arginine-depleted human tumor necrosis factor |
-
1991
- 1991-09-20 AT AT91116017T patent/ATE141093T1/de not_active IP Right Cessation
- 1991-09-20 DE DE69121227T patent/DE69121227T2/de not_active Expired - Fee Related
- 1991-09-20 EP EP91116017A patent/EP0477791B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0477791A3 (en) | 1993-05-05 |
| DE69121227D1 (de) | 1996-09-12 |
| EP0477791B1 (de) | 1996-08-07 |
| DE69121227T2 (de) | 1997-02-20 |
| EP0477791A2 (de) | 1992-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |