ATE141271T1 - Aminosäure-derivate von chinolin und naphthyridin - Google Patents

Aminosäure-derivate von chinolin und naphthyridin

Info

Publication number
ATE141271T1
ATE141271T1 AT89117428T AT89117428T ATE141271T1 AT E141271 T1 ATE141271 T1 AT E141271T1 AT 89117428 T AT89117428 T AT 89117428T AT 89117428 T AT89117428 T AT 89117428T AT E141271 T1 ATE141271 T1 AT E141271T1
Authority
AT
Austria
Prior art keywords
amino acid
naphthyridine
quinoline
acid derivatives
amino
Prior art date
Application number
AT89117428T
Other languages
English (en)
Inventor
Daniel Tim-Wo Chu
Robert Hallas
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/400,111 external-priority patent/US5057520A/en
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE141271T1 publication Critical patent/ATE141271T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0827Tripeptides containing heteroatoms different from O, S, or N
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1027Tetrapeptides containing heteroatoms different from O, S, or N
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT89117428T 1988-09-22 1989-09-21 Aminosäure-derivate von chinolin und naphthyridin ATE141271T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24799088A 1988-09-22 1988-09-22
US31326089A 1989-02-21 1989-02-21
US32840189A 1989-03-24 1989-03-24
US07/400,111 US5057520A (en) 1989-03-24 1989-09-01 7-(peptidylpyrolidinyl)naphthyridine antibacterial compounds

Publications (1)

Publication Number Publication Date
ATE141271T1 true ATE141271T1 (de) 1996-08-15

Family

ID=27500274

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89117428T ATE141271T1 (de) 1988-09-22 1989-09-21 Aminosäure-derivate von chinolin und naphthyridin

Country Status (12)

Country Link
EP (1) EP0360258B1 (de)
JP (1) JP2938898B2 (de)
KR (1) KR100189474B1 (de)
AT (1) ATE141271T1 (de)
AU (1) AU616053B2 (de)
DE (1) DE68926941T2 (de)
DK (1) DK173511B1 (de)
ES (1) ES2092991T3 (de)
GR (1) GR3021342T3 (de)
IE (1) IE76284B1 (de)
IL (1) IL91648A (de)
NZ (1) NZ230727A (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676445B1 (fr) * 1991-05-16 1995-02-03 Esteve Labor Dr Derives de pyridone amino acide azetidinyl substitues, leur preparation et leur application en tant que medicaments.
JP3113440B2 (ja) * 1992-03-25 2000-11-27 日本臓器製薬株式会社 ピリジニウム誘導体
TW252107B (de) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
JP3242792B2 (ja) * 1994-08-05 2001-12-25 日本臓器製薬株式会社 ナフチリジニウム誘導体
KR19980701625A (ko) * 1995-01-24 1998-06-25 이토 마사노리 퀴놀린카르본산유도체
US6613537B2 (en) 2000-02-29 2003-09-02 Nippon Zoki Pharmaceutical Co., Ltd. Pyrrolopyridinium derivatives
US7067148B2 (en) 2001-02-15 2006-06-27 King Pharmaceutical Research & Development, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US7589233B2 (en) 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
US8173840B2 (en) 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
KR101029764B1 (ko) * 2010-12-01 2011-04-19 라현수 축산분뇨, 하수슬러지를 토양미생물을 이용하여 발효시키는 장치 및 이를 이용한 발효퇴비 제조방법
CN103396396B (zh) * 2013-08-12 2015-09-09 西南大学 胺基烷酰克林沙星及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4479898A (en) * 1982-05-18 1984-10-30 Smithkline Beckman Corporation Oligopeptide prodrugs
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
US4604401A (en) * 1984-07-20 1986-08-05 Warner-Lambert Company Antibacterial agents III
US4962112A (en) * 1987-08-04 1990-10-09 Abbott Laboratories 7-(2-methyl-4-aminopyrrolidinyl)naphthryidine and quinoline compounds
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent

Also Published As

Publication number Publication date
DE68926941T2 (de) 1997-03-20
JP2938898B2 (ja) 1999-08-25
EP0360258A3 (de) 1991-06-05
EP0360258B1 (de) 1996-08-14
DE68926941D1 (de) 1996-09-19
AU616053B2 (en) 1991-10-17
GR3021342T3 (en) 1997-01-31
KR900004732A (ko) 1990-04-12
IE76284B1 (en) 1997-10-08
JPH02142786A (ja) 1990-05-31
EP0360258A2 (de) 1990-03-28
DK466889A (da) 1990-03-23
IL91648A (en) 1997-03-18
DK466889D0 (da) 1989-09-21
IE892964L (en) 1990-03-22
IL91648A0 (en) 1990-04-29
AU4172489A (en) 1990-04-26
ES2092991T3 (es) 1996-12-16
NZ230727A (en) 1991-08-27
DK173511B1 (da) 2001-01-15
KR100189474B1 (ko) 1999-06-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee