ATE141493T1 - Knochenersatzwerkstoff und verfahren zu seiner herstellung - Google Patents

Knochenersatzwerkstoff und verfahren zu seiner herstellung

Info

Publication number
ATE141493T1
ATE141493T1 AT93101970T AT93101970T ATE141493T1 AT E141493 T1 ATE141493 T1 AT E141493T1 AT 93101970 T AT93101970 T AT 93101970T AT 93101970 T AT93101970 T AT 93101970T AT E141493 T1 ATE141493 T1 AT E141493T1
Authority
AT
Austria
Prior art keywords
sheet
mixture
animal
bone
producing
Prior art date
Application number
AT93101970T
Other languages
English (en)
Inventor
Michio Ito
Hiroshi Yagasaki
Original Assignee
Matsumoto Dental College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP02411192A external-priority patent/JP3208586B2/ja
Priority claimed from JP02410692A external-priority patent/JP3208585B2/ja
Application filed by Matsumoto Dental College filed Critical Matsumoto Dental College
Application granted granted Critical
Publication of ATE141493T1 publication Critical patent/ATE141493T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/54—Filling; Sealing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/876—Calcium oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Dental Preparations (AREA)
AT93101970T 1992-02-10 1993-02-09 Knochenersatzwerkstoff und verfahren zu seiner herstellung ATE141493T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP02411192A JP3208586B2 (ja) 1992-02-10 1992-02-10 シート状骨補填剤の製造方法
JP02410692A JP3208585B2 (ja) 1992-02-10 1992-02-10 硬化型中性骨形成物の製造方法

Publications (1)

Publication Number Publication Date
ATE141493T1 true ATE141493T1 (de) 1996-09-15

Family

ID=26361594

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93101970T ATE141493T1 (de) 1992-02-10 1993-02-09 Knochenersatzwerkstoff und verfahren zu seiner herstellung

Country Status (4)

Country Link
US (1) US6214048B1 (de)
EP (1) EP0555807B1 (de)
AT (1) ATE141493T1 (de)
DE (1) DE69304092T2 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5507813A (en) * 1993-12-09 1996-04-16 Osteotech, Inc. Shaped materials derived from elongate bone particles
IT1295308B1 (it) * 1997-10-10 1999-05-04 Gentili Ist Spa Complessi amorfi di chitosani e sali insolubili di metalli alcalino terrosi e loro uso come medicamenti utili nella osteogenesi
JP3143660B2 (ja) * 1997-11-27 2001-03-07 工業技術院長 亜鉛含有リン酸三カルシウムからなるセラミックス及び亜鉛徐放性生体用セラミックス
US6030635A (en) * 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
KR100563476B1 (ko) * 1998-07-03 2006-03-27 이진용 골재생재료
WO2000023123A1 (en) * 1998-10-19 2000-04-27 Synthes Ag Chur Hardenable ceramic hydraulic cement
US7168952B2 (en) * 1999-05-12 2007-01-30 Pentron Clinical Technologies, Llc Endodontic post and obturating system
US7163401B2 (en) * 1999-05-12 2007-01-16 Pentron Clinical Technologies, Llc Endodontic post and obturating system
US7086864B2 (en) * 1999-05-12 2006-08-08 Pentron Clinical Technologies, Llc Endodontic post system
JP4472804B2 (ja) * 1999-05-18 2010-06-02 学校法人松本歯科大学 骨補填剤及びその製造方法
CA2377435A1 (en) 1999-06-29 2001-01-04 J. Alexander Marchosky Compositions and methods for forming and strengthening bone
US20030228288A1 (en) 1999-10-15 2003-12-11 Scarborough Nelson L. Volume maintaining osteoinductive/osteoconductive compositions
US9387094B2 (en) 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
ES2169681B1 (es) * 2000-08-10 2003-10-01 Osfarma S L Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.
US7323193B2 (en) 2001-12-14 2008-01-29 Osteotech, Inc. Method of making demineralized bone particles
JP4197157B2 (ja) * 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 軟骨修復再生装置および方法
JP4302515B2 (ja) * 2001-07-16 2009-07-29 デピュイ・プロダクツ・インコーポレイテッド 単体型外科装置および方法
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US20030032961A1 (en) * 2001-07-16 2003-02-13 Pelo Mark Joseph Devices from naturally occurring biologically derived materials
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
AU2002316694B2 (en) * 2001-07-16 2007-09-06 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
US8092529B2 (en) * 2001-07-16 2012-01-10 Depuy Products, Inc. Meniscus regeneration device
EP1434608B1 (de) 2001-10-12 2018-08-22 Warsaw Orthopedic, Inc. Verbessertes knochenimplantat
US7204874B2 (en) * 2001-10-24 2007-04-17 Pentron Clinical Technologies, Llc Root canal filling material
US7303817B2 (en) * 2001-10-24 2007-12-04 Weitao Jia Dental filling material
US7204875B2 (en) * 2001-10-24 2007-04-17 Pentron Clinical Technologies, Llc Dental filling material
JP2003128704A (ja) 2001-10-24 2003-05-08 Matsumoto Shika Univ キチン・キトサンの低分子化方法及び骨伝導物の製造方法
US7211136B2 (en) * 2001-10-24 2007-05-01 Pentron Clinical Technologies, Llc Dental filling material
US7750063B2 (en) 2001-10-24 2010-07-06 Pentron Clinical Technologies, Llc Dental filling material
AU2002362220A1 (en) 2001-12-27 2003-07-24 Osteotech Inc. Bone fasteners and method for stabilizing vertebral bone facets using the bone fasteners
NZ544050A (en) 2003-06-11 2009-03-31 Osteotech Inc Osteoimplants and methods for their manufacture
DE602004031847D1 (de) * 2003-08-08 2011-04-28 Argonne Nat Lab Argonne Verfahren und produkt für eine phosphosilikataufschlämmung zur verwendung in der zahnmedizin und knochenzemente in verbindung damit
JP2005087440A (ja) * 2003-09-17 2005-04-07 Matsumoto Shika Univ 海洋生物の原料を含む組成物、及びその組成物の製造方法
US7569233B2 (en) 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
SE528360C2 (sv) * 2004-09-10 2006-10-24 Doxa Ab Resorberbara keramiska kompositioner avsedda för medicinska implantat
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
WO2007056671A1 (en) 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
EP1962713A2 (de) * 2005-11-25 2008-09-03 Lietzau, Markus Verwendung von knochenklebstoff zur abdichtung eines apikalen foramens
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US8722075B2 (en) 2008-10-24 2014-05-13 Warsaw Orthopedic, Inc. Compositions and methods for promoting bone formation
US20100268341A1 (en) * 2009-04-16 2010-10-21 WARSAW ORTHOPEDIC, INC., An Indian Corporation Minimally invasive expandable vertebral implant and method
CO6530149A1 (es) * 2011-03-28 2012-09-28 Sur Occidental De Aceites Biocompuesto ceramico para regeneracion osea
US9040093B2 (en) * 2013-03-13 2015-05-26 Orthovita, Inc. Bone graft materials containing calcium phosphate and chitosan
CN103656753B (zh) * 2013-12-04 2015-04-22 上海纳米技术及应用国家工程研究中心有限公司 磷酸钙系中性骨水泥及其制备方法
EP3388092A1 (de) 2017-04-13 2018-10-17 Septodont ou Septodont SAS ou Specialites Septodont Bindegewebe, wie knochen, dentin oder zellstoff, regeneratives material mit kalziumsilikat
WO2018189384A1 (en) 2017-04-13 2018-10-18 Septodont Ou Septodont Sas Ou Specialites Septodont Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate
CN112220964A (zh) * 2020-10-19 2021-01-15 西安点云生物科技有限公司 一种复合生物陶瓷粉及其制备的复合生物陶瓷人工骨和制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2101036A1 (en) * 1970-08-12 1972-03-31 Meyer Jean Dentine treatment - using compsn contg trioxymethylene
JPS585861B2 (ja) 1975-08-13 1983-02-02 ミサワホ−ム株式会社 キカイテキキヨウドノ スグレタスイコウセイムキブツシツノ セイゾウホウホウ
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
US4772591A (en) 1985-09-25 1988-09-20 Peritain, Ltd. Method for accelerated wound healing
US5180426A (en) * 1987-12-28 1993-01-19 Asahi Kogaku Kogyo K.K. Composition for forming calcium phosphate type setting material and process for producing setting material
JPH0735281B2 (ja) 1988-02-16 1995-04-19 学校法人松本歯科大学 硬化性組成物
GB8813033D0 (en) * 1988-06-02 1988-07-06 Geistlich Soehne Ag Chemical compound
EP0389629B1 (de) * 1988-08-10 1994-05-11 Nitta Gelatin Inc. Ärztliches und zahnärztliches vernetzbares material
JPH02241460A (ja) 1989-03-16 1990-09-26 Asahi Optical Co Ltd 骨修復用複合材料
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair

Also Published As

Publication number Publication date
US6214048B1 (en) 2001-04-10
EP0555807B1 (de) 1996-08-21
DE69304092T2 (de) 1997-01-02
DE69304092D1 (de) 1996-09-26
EP0555807A1 (de) 1993-08-18

Similar Documents

Publication Publication Date Title
DE69304092D1 (de) Knochenersatzwerkstoff und Verfahren zu seiner Herstellung
ATE74751T1 (de) Oestradiol-implantat und verfahren zu seiner herstellung.
ES2188139T3 (es) Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico.
CA2147766A1 (en) Process for treating a metallic surgical implant
ATE279950T1 (de) Zusammensetzung zur implantation in den menschlichen und tierischen körper
EP0280519A3 (en) Bacterial inhibiting compositions and use thereof
PL292095A1 (en) Pesticides and method of obtaining them
DE69032848D1 (de) Dosierungsmittel und dessen Verwendung
GR3024277T3 (en) Tgf-beta formulation for inducing bone growth.
ZA821949B (en) Process and composition for conditioning an aqueous system
DE3266525D1 (en) Collagen inclusion containing an active substance for introduction in bone or soft tissues, and method for its preparation
AU8434898A (en) Hydroxylapatite gel
IL98464A0 (en) Dibenzoylalkylcyano-hydrazines,their preparation and their use as pesticides
IL72886A0 (en) Biopolymer formulations and their preparation
WO1998043685A3 (de) Antibiotikumhaltige knochenzementpaste
IL121917A0 (en) Method of preventing animal diseases and promoting animal growth and development
HUT62758A (en) Herbicides comprising substituted pyrimidine derivative as active ingredient and process for producing the active ingredients
ES8506062A1 (es) Un procedimiento para producir un lodo no peligroso para el medio ambiente a partir de una solucion acuosa que contiene metales pesados
SE9302672L (sv) Cement för medicinskt bruk, förfarande för framställning av cementet samt användning av cementet
IE802697L (en) Treatment of hazardous waste.
HU9302534D0 (en) Aqueous coating compositions and aqueous emulsions, method for producing them and their applications
EP0493737A3 (de) Einen basischen Fibroblastwachstumsfaktor enthaltende Mittel zur Behandlung von Knochenkrankheiten
DE3267766D1 (en) N-cyclohexyl-chloroacetamides, their preparation and their use in combating undesired plant growth
HUT46842A (en) Biocompatible layered body containing calcium phosphate and method for producing same
HUT53616A (en) Herbicides comprising n-phenyl tetrahydroindazole derivatives as active ingredient and process for producing the active ingredients