ATE141517T1 - Gen-sequenzentransfer und -exprimierung bei zellen des zentralen nervensystems mit mutierenden herpes-simplex-viren, die deletionen in viren-replikationsgenen enthalten - Google Patents

Gen-sequenzentransfer und -exprimierung bei zellen des zentralen nervensystems mit mutierenden herpes-simplex-viren, die deletionen in viren-replikationsgenen enthalten

Info

Publication number
ATE141517T1
ATE141517T1 AT91303387T AT91303387T ATE141517T1 AT E141517 T1 ATE141517 T1 AT E141517T1 AT 91303387 T AT91303387 T AT 91303387T AT 91303387 T AT91303387 T AT 91303387T AT E141517 T1 ATE141517 T1 AT E141517T1
Authority
AT
Austria
Prior art keywords
nervous system
central nervous
herpes simplex
expression
gene sequence
Prior art date
Application number
AT91303387T
Other languages
English (en)
Inventor
Xandra O Breakfield
Robert L Martuza
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24023846&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE141517(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE141517T1 publication Critical patent/ATE141517T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Wood Science & Technology (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91303387T 1990-04-16 1991-04-16 Gen-sequenzentransfer und -exprimierung bei zellen des zentralen nervensystems mit mutierenden herpes-simplex-viren, die deletionen in viren-replikationsgenen enthalten ATE141517T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50873190A 1990-04-16 1990-04-16

Publications (1)

Publication Number Publication Date
ATE141517T1 true ATE141517T1 (de) 1996-09-15

Family

ID=24023846

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91303387T ATE141517T1 (de) 1990-04-16 1991-04-16 Gen-sequenzentransfer und -exprimierung bei zellen des zentralen nervensystems mit mutierenden herpes-simplex-viren, die deletionen in viren-replikationsgenen enthalten

Country Status (8)

Country Link
EP (1) EP0453242B1 (de)
JP (1) JPH0795885A (de)
AT (1) ATE141517T1 (de)
CA (1) CA2039921A1 (de)
DE (1) DE69121452T2 (de)
DK (1) DK0453242T3 (de)
ES (1) ES2090243T3 (de)
GR (1) GR3021426T3 (de)

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Also Published As

Publication number Publication date
DE69121452D1 (de) 1996-09-26
ES2090243T3 (es) 1996-10-16
GR3021426T3 (en) 1997-01-31
DE69121452T2 (de) 1997-01-02
DK0453242T3 (da) 1996-09-16
JPH0795885A (ja) 1995-04-11
EP0453242A1 (de) 1991-10-23
CA2039921A1 (en) 1991-10-17
EP0453242B1 (de) 1996-08-21

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