ATE142203T1 - N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide - Google Patents

N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Info

Publication number: ATE142203T1
Authority: AT; Austria
Prior art keywords: alkyl; iodopropargyl; halogen; optionally substituted; microbicides
Prior art date: 1992-05-26

Application number

AT93303988T

Other languages

English (en)

Inventor

Adam Chi-Tung Hsu

Steven Howard Shaber

Enrique Luis Michelotti

Original Assignee

Rohm & Haas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-26

Filing date

1993-05-21

Publication date

1996-09-15

1993-05-21 Application filed by Rohm & Haas filed Critical Rohm & Haas

1996-09-15 Application granted granted Critical

1996-09-15 Publication of ATE142203T1 publication Critical patent/ATE142203T1/de

Links

MTJCBSAKBGOUDG-UHFFFAOYSA-N 1-iodo-3-prop-2-ynylimidazolidine-2,4-dione Chemical class IN1CC(=O)N(CC#C)C1=O MTJCBSAKBGOUDG-UHFFFAOYSA-N 0.000 title 1
229940124561 microbicide Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1
125000005843 halogen group Chemical group 0.000 abstract 4
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000006583 (C1-C3) haloalkyl group Chemical group 0.000 abstract 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
239000003429 antifungal agent Substances 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
150000001469 hydantoins Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
125000003003 spiro group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Agronomy & Crop Science (AREA)
Dentistry (AREA)
Wood Science & Technology (AREA)
Plant Pathology (AREA)
Zoology (AREA)
Pest Control & Pesticides (AREA)
Environmental Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Veterinary Medicine (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Apparatus For Disinfection Or Sterilisation (AREA)
Cosmetics (AREA)
Fodder In General (AREA)
Plural Heterocyclic Compounds (AREA)

AT93303988T 1992-05-26 1993-05-21 N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide ATE142203T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/888,572 US5346913A (en)	1992-05-26	1992-05-26	N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents

Publications (1)

Publication Number	Publication Date
ATE142203T1 true ATE142203T1 (de)	1996-09-15

Family

ID=25393441

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93303988T ATE142203T1 (de)	1992-05-26	1993-05-21	N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Country Status (8)

Country	Link
US (1)	US5346913A (de)
EP (1)	EP0572191B1 (de)
JP (1)	JPH0656796A (de)
AT (1)	ATE142203T1 (de)
BR (1)	BR9302068A (de)
CA (1)	CA2096395A1 (de)
DE (1)	DE69304420T2 (de)
MX (1)	MX9302944A (de)

Families Citing this family (32)

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CA2216765A1 (en) *	1996-10-11	1998-04-11	Rohm And Haas Company	Halopropargyl compounds as marine antifouling agents
US6143204A (en) *	1998-06-19	2000-11-07	Lonza Inc.	Stabilization of iodopropynl compounds
WO2002067685A1 (en) *	2001-02-26	2002-09-06	Lonza Inc.	Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent
CA2450073C (en)	2001-07-25	2017-08-29	Biomarin Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
DE60234264D1 (de) *	2001-10-01	2009-12-17	Bristol Myers Squibb Co	Spiro-hydantoin-verbindungen, die sich als entzündungshemmende mittel eignen
JP2005104835A (ja) *	2001-10-10	2005-04-21	Kaneka Corp	新規５−置換ヒダントイン誘導体及びその製造方法
NZ550102A (en)	2004-02-24	2010-10-29	Univ California	Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives)
US20050203156A1 (en) *	2004-03-12	2005-09-15	Wyeth	Hydantoins having RNase modulatory activity
TW200616634A (en) *	2004-10-01	2006-06-01	Bristol Myers Squibb Co	Crystalline forms and process for preparing spiro-hydantoin compounds
US7186727B2 (en) *	2004-12-14	2007-03-06	Bristol-Myers Squibb Company	Pyridyl-substituted spiro-hydantoin compounds and use thereof
US20060142319A1 (en) *	2004-12-14	2006-06-29	Bang-Chi Chen	Pyridyl-substituted spiro-hydantoin crystalline forms and process
EP2671508B1 (de)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Pharma-Informatiksystem
US7709517B2 (en)	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
CN100397998C (zh) *	2006-03-16	2008-07-02	上海交通大学	复合型霉菌毒素吸附剂
BRPI0709771B1 (pt)	2006-03-27	2022-01-25	The Regents Of The University Of California	Composto e composição farmacêutica
NZ596260A (en)	2006-03-29	2013-05-31	Univ California	Diarylthiohydantoin compounds
US8168667B2 (en)	2006-05-31	2012-05-01	Galapagos Nv	Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such
CN101528711A (zh)	2006-08-31	2009-09-09	先灵公司	可用作抗细菌剂的乙内酰脲衍生物
JP2010503710A (ja)	2006-09-18	2010-02-04	ラプトールファーマシューティカルインコーポレイテッド	受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
TWI469971B (zh)	2007-10-26	2015-01-21	Univ California	二芳基乙內醯脲類化合物
GB2463514C (en)	2008-09-11	2018-09-26	Galapagos Nv	Imidazolidine compounds and uses therefor
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko)	2009-05-06	2018-10-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
EP3124481B1 (de)	2010-02-16	2018-03-28	Aragon Pharmaceuticals, Inc.	Androgenrezeptormodulatoren und verwendungen davon
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates
WO2014052237A1 (en)	2012-09-26	2014-04-03	Aragon Pharmaceuticals, Inc.	Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
EP2945628B1 (de)	2013-01-15	2020-04-15	Aragon Pharmaceuticals, Inc.	Androgenrezeptormodulator in kombination mit abirateronacetat und prednison zur behandlung von prostatkrebs
CN105399681A (zh) *	2014-08-22	2016-03-16	中国航天科工集团第六研究院四十六所	1,3-双(丙炔基)-5,5-二甲基海因及其合成方法和应用
TWI726969B (zh)	2016-01-11	2021-05-11	比利時商健生藥品公司	用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
KR20240096623A (ko)	2017-10-16	2024-06-26	아라곤 파마슈티컬스, 인코포레이티드	비-전이성 거세-저항성 전립선암의 치료를 위한 항-안드로겐
CN111533694B (zh) *	2020-06-05	2023-03-14	河南牧业经济学院	一种2-亚胺基乙内酰脲化合物的合成方法
RU2763731C1 (ru) *	2021-06-17	2021-12-30	Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ)	Применение 9-ароил-8-гидрокси-6-(2-гидроксиалкил)-1,3-диалкил-2-тиоксо-1,3,6-триазаспиро[4.4]нон-8-ен-4,7-дионов в качестве средств, обладающих противомикробной активностью

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JPS57197268A (en) *	1981-05-29	1982-12-03	Sumitomo Chem Co Ltd	Substituted phenylhydantoin derivative, its preparation, and herbicide containing the same as active ingredient
US4753957A (en) *	1981-09-28	1988-06-28	Rohm And Haas Company	Substituted 2,4-imidazolidinediones and fungicidal compositions
DE3241265A1 (de) *	1982-11-09	1984-05-10	Bayer Ag, 5090 Leverkusen	3-(3-jodpropargyl)-benzo-1,2,3-triazin-4-one, verfahren zu ihrer herstellung und ihre verwendung in mikrobiziden mitteln
US4616004A (en) *	1984-09-27	1986-10-07	Chevron Research Company	1-iodopropargyl-3,4-disubstituted-Δ2 -1,2,4-triazolidin-5-one fungicides
US4639460A (en) *	1985-08-05	1987-01-27	Chevron Research Company	Fungicidal substituted N-(1-iodopropargyl)thiazolidinones
US4827020A (en) *	1987-03-24	1989-05-02	Sumitomo Chemical Company, Limited	Propargyl amide precursor to 1-propargyl-2,4-dioxoimidazolidine
CA2019162A1 (en) *	1989-06-22	1990-12-22	Adam Chi-Tung Hsu	Halopropargyl compounds, compositions, uses and processes of preparation
IT1268325B1 (it) *	1994-08-05	1997-02-27	Sasib Spa	Macchina impacchettatrice per oggetti astiformi delicati, in particolare per sigarette, o simili.

1992
- 1992-05-26 US US07/888,572 patent/US5346913A/en not_active Expired - Fee Related
1993
- 1993-05-17 CA CA002096395A patent/CA2096395A1/en not_active Abandoned
- 1993-05-20 MX MX9302944A patent/MX9302944A/es not_active Application Discontinuation
- 1993-05-21 EP EP93303988A patent/EP0572191B1/de not_active Expired - Lifetime
- 1993-05-21 DE DE69304420T patent/DE69304420T2/de not_active Expired - Fee Related
- 1993-05-21 AT AT93303988T patent/ATE142203T1/de not_active IP Right Cessation
- 1993-05-26 BR BR9302068A patent/BR9302068A/pt not_active Application Discontinuation
- 1993-05-26 JP JP5146979A patent/JPH0656796A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
EP0572191A1 (de)	1993-12-01
US5346913A (en)	1994-09-13
JPH0656796A (ja)	1994-03-01
CA2096395A1 (en)	1993-11-27
BR9302068A (pt)	1993-11-30
MX9302944A (es)	1994-05-31
EP0572191B1 (de)	1996-09-04
DE69304420T2 (de)	1997-03-13
DE69304420D1 (de)	1996-10-10

Legal Events

Date	Code	Title	Description
1997-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69304420D1 (de)	1996-10-10	N-Iodopropargyl-Hydantoin-Verbindungen, Zusammensetzungen, Herstellung und Verwendung als Mikrobizide
AU643310B2 (en)	1993-11-11	Isoxazole derivatives
DE3786365D1 (de)	1993-08-05	5h-1,3,4-thiadiazolo(3,2-a)pyrimidin-5-on-derivate und diese enthaltende gartenbau- und landwirtschaftliche fungizidmittel.
ATE179707T1 (de)	1999-05-15	Tetrazolinon-herbizide
SE8002345L (sv)	1980-11-14	Terapeutiska medel
NO924783D0 (no)	1992-12-10	Terapeutiske midler
HUT56809A (en)	1991-10-28	Herbicidal composition comprising 2-(2', 3', 4'-trisubstituted benzoyl)-1,3-cyclohexanedione derivatives as active ingredient
FI872555A0 (fi)	1987-06-08	Antiallergiska och antiinflammatoriska aemnen.
GR3003776T3 (de)	1993-03-16
DK0841327T3 (da)	2002-01-21	Triazolantisvampemiddel
DK0436348T3 (da)	1997-04-14	Pyridylcyklopropanderivater med fungicid aktivitet
MY130817A (en)	2007-07-31	Herbicides
DE3061188D1 (en)	1983-01-05	2-sulfonyl-quinoxalines, processes for their preparation and their use as microbicides
ATE73759T1 (de)	1992-04-15	Fungizide.
IL98987A0 (en)	1992-07-15	Heterocyclic compounds,their preparation and their use as pesticides
JPS54115315A (en)	1979-09-07	Insecticide and tickicide intermediate and its manufacture
DE2961326D1 (en)	1982-01-14	New 1,2,4-triazole derivatives, a process for their manufacture and pharmaceutical compositions containing them
ATE148462T1 (de)	1997-02-15	Isoxazole derivate als lichtschutzmittel
BG96022A (bg)	1993-12-24	2-(2'метил-3',4'-тризаместени бензол)-1,3- циклохександиони, метод за борба срещу нежелана растителност и хербициден състав, използващ тези съединения