ATE142203T1 - N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide - Google Patents

N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Info

Publication number: ATE142203T1
Authority: AT; Austria
Prior art keywords: alkyl; iodopropargyl; halogen; optionally substituted; microbicides
Prior art date: 1992-05-26

Application number

AT93303988T

Other languages

English (en)

Inventor

Adam Chi-Tung Hsu

Steven Howard Shaber

Enrique Luis Michelotti

Original Assignee

Rohm & Haas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-26

Filing date

1993-05-21

Publication date

1996-09-15

1993-05-21 Application filed by Rohm & Haas filed Critical Rohm & Haas

1996-09-15 Application granted granted Critical

1996-09-15 Publication of ATE142203T1 publication Critical patent/ATE142203T1/de

Links

MTJCBSAKBGOUDG-UHFFFAOYSA-N 1-iodo-3-prop-2-ynylimidazolidine-2,4-dione Chemical class IN1CC(=O)N(CC#C)C1=O MTJCBSAKBGOUDG-UHFFFAOYSA-N 0.000 title 1
229940124561 microbicide Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1
125000005843 halogen group Chemical group 0.000 abstract 4
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000006583 (C1-C3) haloalkyl group Chemical group 0.000 abstract 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
239000003429 antifungal agent Substances 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
150000001469 hydantoins Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
125000003003 spiro group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Dentistry (AREA)
Engineering & Computer Science (AREA)
Plant Pathology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Pest Control & Pesticides (AREA)
Agronomy & Crop Science (AREA)
Oncology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Communicable Diseases (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Fodder In General (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Apparatus For Disinfection Or Sterilisation (AREA)
Cosmetics (AREA)
Plural Heterocyclic Compounds (AREA)

AT93303988T 1992-05-26 1993-05-21 N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide ATE142203T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/888,572 US5346913A (en)	1992-05-26	1992-05-26	N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents

Publications (1)

Publication Number	Publication Date
ATE142203T1 true ATE142203T1 (de)	1996-09-15

Family

ID=25393441

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93303988T ATE142203T1 (de)	1992-05-26	1993-05-21	N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Country Status (8)

Country	Link
US (1)	US5346913A (de)
EP (1)	EP0572191B1 (de)
JP (1)	JPH0656796A (de)
AT (1)	ATE142203T1 (de)
BR (1)	BR9302068A (de)
CA (1)	CA2096395A1 (de)
DE (1)	DE69304420T2 (de)
MX (1)	MX9302944A (de)

Families Citing this family (32)

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Publication number	Priority date	Publication date	Assignee	Title
CA2216765A1 (en) *	1996-10-11	1998-04-11	Rohm And Haas Company	Halopropargyl compounds as marine antifouling agents
US6143204A (en) *	1998-06-19	2000-11-07	Lonza Inc.	Stabilization of iodopropynl compounds
WO2002067685A1 (en) *	2001-02-26	2002-09-06	Lonza Inc.	Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent
WO2003009815A2 (en)	2001-07-25	2003-02-06	Biomarin Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
ES2339107T3 (es) *	2001-10-01	2010-05-17	Bristol-Myers Squibb Company	Compuestos de espiro hidantoina utiles como agentes anti-inflamatorios.
JP2005104835A (ja) *	2001-10-10	2005-04-21	Kaneka Corp	新規５−置換ヒダントイン誘導体及びその製造方法
WO2005099693A2 (en)	2004-02-24	2005-10-27	The Regents Of The University Of California	Methods and materials for assessing prostate cancer therapies and compounds
US20050203156A1 (en) *	2004-03-12	2005-09-15	Wyeth	Hydantoins having RNase modulatory activity
TW200616634A (en) *	2004-10-01	2006-06-01	Bristol Myers Squibb Co	Crystalline forms and process for preparing spiro-hydantoin compounds
US7186727B2 (en) *	2004-12-14	2007-03-06	Bristol-Myers Squibb Company	Pyridyl-substituted spiro-hydantoin compounds and use thereof
US20060142319A1 (en) *	2004-12-14	2006-06-29	Bang-Chi Chen	Pyridyl-substituted spiro-hydantoin crystalline forms and process
SI1889198T1 (sl)	2005-04-28	2015-02-27	Proteus Digital Health, Inc.	Farma-informacijski sistem
US7709517B2 (en)	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
CN100397998C (zh) *	2006-03-16	2008-07-02	上海交通大学	复合型霉菌毒素吸附剂
ES2593379T3 (es)	2006-03-27	2016-12-09	The Regents Of The University Of California	Modulador del receptor de andrógenos para el tratamiento del cáncer de próstata y enfermedades asociadas con el receptor de andrógenos
EP2439196A1 (de)	2006-03-29	2012-04-11	The Regents of The University of California	Diarylthiohydantoin-Verbindungen zur Anwendung in einem Verfahren zur Behandlung einer hyperproliferativen Erkrankung
US8168667B2 (en)	2006-05-31	2012-05-01	Galapagos Nv	Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such
WO2008027466A1 (en) *	2006-08-31	2008-03-06	Schering Corporation	Hydantoin derivatives useful as antibacterial agents
EP2063905B1 (de)	2006-09-18	2014-07-30	Raptor Pharmaceutical Inc	Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
US8680291B2 (en)	2007-10-26	2014-03-25	The Regents Of The University Of California	Diarylhydantoin compounds
GB2463514C (en)	2008-09-11	2018-09-26	Galapagos Nv	Imidazolidine compounds and uses therefor
DK2398500T3 (da)	2009-02-20	2019-05-13	2 Bbb Medicines B V	Glutathion-baseret lægemiddelafgivelsessystem
SG175896A1 (en)	2009-05-06	2011-12-29	Lab Skin Care Inc	Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
KR101819199B1 (ko)	2010-02-16	2018-01-16	아라곤 파마슈티컬스, 인코포레이티드	안드로겐 수용체 조절제 및 이의 용도
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates
SG10201902568YA (en)	2012-09-26	2019-04-29	Aragon Pharmaceuticals Inc	Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
LT2945628T (lt)	2013-01-15	2020-05-25	Aragon Pharmaceuticals, Inc.	Androgeno receptoriaus moduliatorius derinyje su abiraterono acetatu ir prednizonu, skirtas prostatos vėžio gydymui
CN105399681A (zh) *	2014-08-22	2016-03-16	中国航天科工集团第六研究院四十六所	1,3-双(丙炔基)-5,5-二甲基海因及其合成方法和应用
TWI726969B (zh)	2016-01-11	2021-05-11	比利時商健生藥品公司	用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
WO2019078920A1 (en)	2017-10-16	2019-04-25	Aragon Pharmaceuticals, Inc.	ANTI-ANDROGENS FOR THE TREATMENT OF NON-METASTATIC RESISTANT PROSTATE CANCER
CN111533694B (zh) *	2020-06-05	2023-03-14	河南牧业经济学院	一种2-亚胺基乙内酰脲化合物的合成方法
RU2763731C1 (ru) *	2021-06-17	2021-12-30	Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ)	Применение 9-ароил-8-гидрокси-6-(2-гидроксиалкил)-1,3-диалкил-2-тиоксо-1,3,6-триазаспиро[4.4]нон-8-ен-4,7-дионов в качестве средств, обладающих противомикробной активностью

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Publication number	Priority date	Publication date	Assignee	Title
JPS57197268A (en) *	1981-05-29	1982-12-03	Sumitomo Chem Co Ltd	Substituted phenylhydantoin derivative, its preparation, and herbicide containing the same as active ingredient
US4753957A (en) *	1981-09-28	1988-06-28	Rohm And Haas Company	Substituted 2,4-imidazolidinediones and fungicidal compositions
DE3241265A1 (de) *	1982-11-09	1984-05-10	Bayer Ag, 5090 Leverkusen	3-(3-jodpropargyl)-benzo-1,2,3-triazin-4-one, verfahren zu ihrer herstellung und ihre verwendung in mikrobiziden mitteln
US4616004A (en) *	1984-09-27	1986-10-07	Chevron Research Company	1-iodopropargyl-3,4-disubstituted-Δ2 -1,2,4-triazolidin-5-one fungicides
US4639460A (en) *	1985-08-05	1987-01-27	Chevron Research Company	Fungicidal substituted N-(1-iodopropargyl)thiazolidinones
US4827020A (en) *	1987-03-24	1989-05-02	Sumitomo Chemical Company, Limited	Propargyl amide precursor to 1-propargyl-2,4-dioxoimidazolidine
CA2019162A1 (en) *	1989-06-22	1990-12-22	Adam Chi-Tung Hsu	Halopropargyl compounds, compositions, uses and processes of preparation
IT1268325B1 (it) *	1994-08-05	1997-02-27	Sasib Spa	Macchina impacchettatrice per oggetti astiformi delicati, in particolare per sigarette, o simili.

1992
- 1992-05-26 US US07/888,572 patent/US5346913A/en not_active Expired - Fee Related
1993
- 1993-05-17 CA CA002096395A patent/CA2096395A1/en not_active Abandoned
- 1993-05-20 MX MX9302944A patent/MX9302944A/es not_active Application Discontinuation
- 1993-05-21 DE DE69304420T patent/DE69304420T2/de not_active Expired - Fee Related
- 1993-05-21 AT AT93303988T patent/ATE142203T1/de not_active IP Right Cessation
- 1993-05-21 EP EP93303988A patent/EP0572191B1/de not_active Expired - Lifetime
- 1993-05-26 JP JP5146979A patent/JPH0656796A/ja not_active Withdrawn
- 1993-05-26 BR BR9302068A patent/BR9302068A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2096395A1 (en)	1993-11-27
JPH0656796A (ja)	1994-03-01
EP0572191B1 (de)	1996-09-04
DE69304420T2 (de)	1997-03-13
EP0572191A1 (de)	1993-12-01
MX9302944A (es)	1994-05-31
DE69304420D1 (de)	1996-10-10
BR9302068A (pt)	1993-11-30
US5346913A (en)	1994-09-13

Legal Events

Date	Code	Title	Description
1997-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE142203T1 (de)	1996-09-15	N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide
IL99132A0 (en)	1992-07-15	Isoxazole derivatives
DE3786365D1 (de)	1993-08-05	5h-1,3,4-thiadiazolo(3,2-a)pyrimidin-5-on-derivate und diese enthaltende gartenbau- und landwirtschaftliche fungizidmittel.
ATE179707T1 (de)	1999-05-15	Tetrazolinon-herbizide
SE8002345L (sv)	1980-11-14	Terapeutiska medel
NO924783L (no)	1993-02-23	Terapeutiske midler
HUT56809A (en)	1991-10-28	Herbicidal composition comprising 2-(2', 3', 4'-trisubstituted benzoyl)-1,3-cyclohexanedione derivatives as active ingredient
FI872555A0 (fi)	1987-06-08	Antiallergiska och antiinflammatoriska aemnen.
ATE71619T1 (de)	1992-02-15	Pyridazinon-derivate.
DK0841327T3 (da)	2002-01-21	Triazolantisvampemiddel
DK0436348T3 (da)	1997-04-14	Pyridylcyklopropanderivater med fungicid aktivitet
MY130817A (en)	2007-07-31	Herbicides
DE3061188D1 (en)	1983-01-05	2-sulfonyl-quinoxalines, processes for their preparation and their use as microbicides
DE3869194D1 (de)	1992-04-23	Fungizide.
IL98987A0 (en)	1992-07-15	Heterocyclic compounds,their preparation and their use as pesticides
JPS54115315A (en)	1979-09-07	Insecticide and tickicide intermediate and its manufacture
BG96022A (bg)	1993-12-24	2-(2'метил-3',4'-тризаместени бензол)-1,3- циклохександиони, метод за борба срещу нежелана растителност и хербициден състав, използващ тези съединения