ATE142203T1 - N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide - Google Patents

N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Info

Publication number: ATE142203T1
Authority: AT; Austria
Prior art keywords: alkyl; iodopropargyl; halogen; optionally substituted; microbicides
Prior art date: 1992-05-26

Application number

AT93303988T

Other languages

English (en)

Inventor

Adam Chi-Tung Hsu

Steven Howard Shaber

Enrique Luis Michelotti

Original Assignee

Rohm & Haas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-26

Filing date

1993-05-21

Publication date

1996-09-15

1993-05-21 Application filed by Rohm & Haas filed Critical Rohm & Haas

1996-09-15 Application granted granted Critical

1996-09-15 Publication of ATE142203T1 publication Critical patent/ATE142203T1/de

Links

MTJCBSAKBGOUDG-UHFFFAOYSA-N 1-iodo-3-prop-2-ynylimidazolidine-2,4-dione Chemical class IN1CC(=O)N(CC#C)C1=O MTJCBSAKBGOUDG-UHFFFAOYSA-N 0.000 title 1
229940124561 microbicide Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1
125000005843 halogen group Chemical group 0.000 abstract 4
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000006583 (C1-C3) haloalkyl group Chemical group 0.000 abstract 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
239000003429 antifungal agent Substances 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
150000001469 hydantoins Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
125000003003 spiro group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Plant Pathology (AREA)
Pest Control & Pesticides (AREA)
Engineering & Computer Science (AREA)
Dentistry (AREA)
Agronomy & Crop Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Oncology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Communicable Diseases (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Fodder In General (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Apparatus For Disinfection Or Sterilisation (AREA)
Cosmetics (AREA)

AT93303988T 1992-05-26 1993-05-21 N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide ATE142203T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/888,572 US5346913A (en)	1992-05-26	1992-05-26	N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents

Publications (1)

Publication Number	Publication Date
ATE142203T1 true ATE142203T1 (de)	1996-09-15

Family

ID=25393441

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93303988T ATE142203T1 (de)	1992-05-26	1993-05-21	N-iodopropargyl-hydantoin-verbindungen, zusammensetzungen, herstellung und verwendung als mikrobizide

Country Status (8)

Country	Link
US (1)	US5346913A (de)
EP (1)	EP0572191B1 (de)
JP (1)	JPH0656796A (de)
AT (1)	ATE142203T1 (de)
BR (1)	BR9302068A (de)
CA (1)	CA2096395A1 (de)
DE (1)	DE69304420T2 (de)
MX (1)	MX9302944A (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2216765A1 (en) *	1996-10-11	1998-04-11	Rohm And Haas Company	Halopropargyl compounds as marine antifouling agents
US6143204A (en) *	1998-06-19	2000-11-07	Lonza Inc.	Stabilization of iodopropynl compounds
WO2002067685A1 (en) *	2001-02-26	2002-09-06	Lonza Inc.	Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent
AU2002322720B2 (en)	2001-07-25	2008-11-13	Raptor Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
IL160990A0 (en) *	2001-10-01	2004-08-31	Bristol Myers Squibb Co	Spiro-hydantoin compounds useful as anti-inflammatory agents
JP2005104835A (ja) *	2001-10-10	2005-04-21	Kaneka Corp	新規５−置換ヒダントイン誘導体及びその製造方法
WO2005099693A2 (en)	2004-02-24	2005-10-27	The Regents Of The University Of California	Methods and materials for assessing prostate cancer therapies and compounds
US20050203156A1 (en) *	2004-03-12	2005-09-15	Wyeth	Hydantoins having RNase modulatory activity
TW200616634A (en) *	2004-10-01	2006-06-01	Bristol Myers Squibb Co	Crystalline forms and process for preparing spiro-hydantoin compounds
US7186727B2 (en) *	2004-12-14	2007-03-06	Bristol-Myers Squibb Company	Pyridyl-substituted spiro-hydantoin compounds and use thereof
US20060142319A1 (en) *	2004-12-14	2006-06-29	Bang-Chi Chen	Pyridyl-substituted spiro-hydantoin crystalline forms and process
CN102379684B (zh)	2005-04-28	2014-11-19	普罗透斯数字保健公司	药物信息系统
US7709517B2 (en)	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
CN100397998C (zh) *	2006-03-16	2008-07-02	上海交通大学	复合型霉菌毒素吸附剂
ES2689292T3 (es)	2006-03-27	2018-11-13	The Regents Of The University Of California	Modulador del receptor de andrógenos para el tratamiento del cáncer de próstata y enfermedades asociadas con el receptor de andrógenos
NZ572374A (en)	2006-03-29	2011-12-22	Univ California	Diarylthiohydantoin compounds
US8168667B2 (en)	2006-05-31	2012-05-01	Galapagos Nv	Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such
JP2010502617A (ja) *	2006-08-31	2010-01-28	シェーリングコーポレイション	抗菌物質として有用なヒダントイン誘導体
KR20090071598A (ko)	2006-09-18	2009-07-01	랩터 파마슈티컬 인코포레이티드	수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2220050A2 (de)	2007-10-26	2010-08-25	The Regents Of The University Of California	Diarylhydantoinverbindungen als androgenrezeptormodulatoren
GB2463514C (en)	2008-09-11	2018-09-26	Galapagos Nv	Imidazolidine compounds and uses therefor
EP2398500B1 (de)	2009-02-20	2019-03-13	2-BBB Medicines B.V.	Arzneiabgabesystem auf glutathion-basis
ES2942923T3 (es)	2009-05-06	2023-06-07	Laboratory Skin Care Inc	Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
SG10201907588XA (en)	2010-02-16	2019-09-27	Aragon Pharmaceuticals Inc	Androgen Receptor Modulators And Uses Thereof
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates
CN115737643A (zh)	2012-09-26	2023-03-07	阿拉贡药品公司	用于治疗非转移性去势抵抗性前列腺癌的抗雄激素
DK2945628T3 (da)	2013-01-15	2020-05-04	Aragon Pharmaceuticals Inc	Androgen receptormodulator i kombination med abirateronacetat og prednison til behandling af prostatacancer
CN105399681A (zh) *	2014-08-22	2016-03-16	中国航天科工集团第六研究院四十六所	1,3-双(丙炔基)-5,5-二甲基海因及其合成方法和应用
TWI726969B (zh)	2016-01-11	2021-05-11	比利時商健生藥品公司	用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
MX2020003845A (es)	2017-10-16	2020-11-06	Aragon Pharmaceuticals Inc	Antiandrógenos para el tratamiento de cáncer de próstata no metastásico resistente a la castración.
CN111533694B (zh) *	2020-06-05	2023-03-14	河南牧业经济学院	一种2-亚胺基乙内酰脲化合物的合成方法
RU2763731C1 (ru) *	2021-06-17	2021-12-30	Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ)	Применение 9-ароил-8-гидрокси-6-(2-гидроксиалкил)-1,3-диалкил-2-тиоксо-1,3,6-триазаспиро[4.4]нон-8-ен-4,7-дионов в качестве средств, обладающих противомикробной активностью

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57197268A (en) *	1981-05-29	1982-12-03	Sumitomo Chem Co Ltd	Substituted phenylhydantoin derivative, its preparation, and herbicide containing the same as active ingredient
US4753957A (en) *	1981-09-28	1988-06-28	Rohm And Haas Company	Substituted 2,4-imidazolidinediones and fungicidal compositions
DE3241265A1 (de) *	1982-11-09	1984-05-10	Bayer Ag, 5090 Leverkusen	3-(3-jodpropargyl)-benzo-1,2,3-triazin-4-one, verfahren zu ihrer herstellung und ihre verwendung in mikrobiziden mitteln
US4616004A (en) *	1984-09-27	1986-10-07	Chevron Research Company	1-iodopropargyl-3,4-disubstituted-Δ2 -1,2,4-triazolidin-5-one fungicides
US4639460A (en) *	1985-08-05	1987-01-27	Chevron Research Company	Fungicidal substituted N-(1-iodopropargyl)thiazolidinones
US4827020A (en) *	1987-03-24	1989-05-02	Sumitomo Chemical Company, Limited	Propargyl amide precursor to 1-propargyl-2,4-dioxoimidazolidine
CA2019162A1 (en) *	1989-06-22	1990-12-22	Adam Chi-Tung Hsu	Halopropargyl compounds, compositions, uses and processes of preparation
IT1268325B1 (it) *	1994-08-05	1997-02-27	Sasib Spa	Macchina impacchettatrice per oggetti astiformi delicati, in particolare per sigarette, o simili.

1992
- 1992-05-26 US US07/888,572 patent/US5346913A/en not_active Expired - Fee Related
1993
- 1993-05-17 CA CA002096395A patent/CA2096395A1/en not_active Abandoned
- 1993-05-20 MX MX9302944A patent/MX9302944A/es not_active Application Discontinuation
- 1993-05-21 EP EP93303988A patent/EP0572191B1/de not_active Expired - Lifetime
- 1993-05-21 AT AT93303988T patent/ATE142203T1/de not_active IP Right Cessation
- 1993-05-21 DE DE69304420T patent/DE69304420T2/de not_active Expired - Fee Related
- 1993-05-26 BR BR9302068A patent/BR9302068A/pt not_active Application Discontinuation
- 1993-05-26 JP JP5146979A patent/JPH0656796A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
JPH0656796A (ja)	1994-03-01
CA2096395A1 (en)	1993-11-27
EP0572191A1 (de)	1993-12-01
EP0572191B1 (de)	1996-09-04
DE69304420D1 (de)	1996-10-10
MX9302944A (es)	1994-05-31
US5346913A (en)	1994-09-13
DE69304420T2 (de)	1997-03-13
BR9302068A (pt)	1993-11-30

Legal Events

Date	Code	Title	Description
1997-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69304420D1 (de)	1996-10-10	N-Iodopropargyl-Hydantoin-Verbindungen, Zusammensetzungen, Herstellung und Verwendung als Mikrobizide
PH30440A (en)	1997-05-09	Isoxazole derivatives
DE3786365D1 (de)	1993-08-05	5h-1,3,4-thiadiazolo(3,2-a)pyrimidin-5-on-derivate und diese enthaltende gartenbau- und landwirtschaftliche fungizidmittel.
ATE179707T1 (de)	1999-05-15	Tetrazolinon-herbizide
SE8002345L (sv)	1980-11-14	Terapeutiska medel
NO924783D0 (no)	1992-12-10	Terapeutiske midler
HUT56809A (en)	1991-10-28	Herbicidal composition comprising 2-(2', 3', 4'-trisubstituted benzoyl)-1,3-cyclohexanedione derivatives as active ingredient
FI872555A0 (fi)	1987-06-08	Antiallergiska och antiinflammatoriska aemnen.
GR3003776T3 (de)	1993-03-16
DK0841327T3 (da)	2002-01-21	Triazolantisvampemiddel
DK0436348T3 (da)	1997-04-14	Pyridylcyklopropanderivater med fungicid aktivitet
MY130817A (en)	2007-07-31	Herbicides
DE3061188D1 (en)	1983-01-05	2-sulfonyl-quinoxalines, processes for their preparation and their use as microbicides
ATE73759T1 (de)	1992-04-15	Fungizide.
IL98987A0 (en)	1992-07-15	Heterocyclic compounds,their preparation and their use as pesticides
JPS54115315A (en)	1979-09-07	Insecticide and tickicide intermediate and its manufacture
DE2961326D1 (en)	1982-01-14	New 1,2,4-triazole derivatives, a process for their manufacture and pharmaceutical compositions containing them
ATE148462T1 (de)	1997-02-15	Isoxazole derivate als lichtschutzmittel
BG96022A (bg)	1993-12-24	2-(2'метил-3',4'-тризаместени бензол)-1,3- циклохександиони, метод за борба срещу нежелана растителност и хербициден състав, използващ тези съединения