ATE142483T1 - Verfahren zur behandlung infizierter gewebe - Google Patents

Verfahren zur behandlung infizierter gewebe

Info

Publication number
ATE142483T1
ATE142483T1 AT93908585T AT93908585T ATE142483T1 AT E142483 T1 ATE142483 T1 AT E142483T1 AT 93908585 T AT93908585 T AT 93908585T AT 93908585 T AT93908585 T AT 93908585T AT E142483 T1 ATE142483 T1 AT E142483T1
Authority
AT
Austria
Prior art keywords
liposomes
entrapped
infected region
vesicle
liposomal composition
Prior art date
Application number
AT93908585T
Other languages
English (en)
Inventor
Martin C Woodle
Irma A J M Bakker-Woudenberg
Francis J Martin
Original Assignee
Sequus Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequus Pharm Inc filed Critical Sequus Pharm Inc
Application granted granted Critical
Publication of ATE142483T1 publication Critical patent/ATE142483T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5537—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93908585T 1992-03-27 1993-03-24 Verfahren zur behandlung infizierter gewebe ATE142483T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/858,171 US5843473A (en) 1989-10-20 1992-03-27 Method of treatment of infected tissues

Publications (1)

Publication Number Publication Date
ATE142483T1 true ATE142483T1 (de) 1996-09-15

Family

ID=25327664

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93908585T ATE142483T1 (de) 1992-03-27 1993-03-24 Verfahren zur behandlung infizierter gewebe

Country Status (7)

Country Link
US (1) US5843473A (de)
EP (1) EP0632719B1 (de)
AT (1) ATE142483T1 (de)
DE (1) DE69304685T2 (de)
DK (1) DK0632719T3 (de)
ES (1) ES2092296T3 (de)
WO (1) WO1993019738A1 (de)

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US5820873A (en) * 1994-09-30 1998-10-13 The University Of British Columbia Polyethylene glycol modified ceramide lipids and liposome uses thereof
US5885613A (en) * 1994-09-30 1999-03-23 The University Of British Columbia Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
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US6673364B1 (en) 1995-06-07 2004-01-06 The University Of British Columbia Liposome having an exchangeable component
US20060089751A1 (en) * 1997-01-27 2006-04-27 Ewa Herbst Electronic delivery systems and methods with feedback
US20110230857A1 (en) * 1997-01-27 2011-09-22 Ewa Herbst Electronic delivery systems and methods with feedback
US5827533A (en) * 1997-02-06 1998-10-27 Duke University Liposomes containing active agents aggregated with lipid surfactants
WO1998046275A2 (en) * 1997-04-11 1998-10-22 The Board Of Regents Of The University Of Michigan Blood-pool carrier for lipophilic imaging agents
US6734171B1 (en) 1997-10-10 2004-05-11 Inex Pharmaceuticals Corp. Methods for encapsulating nucleic acids in lipid bilayers
US20010003580A1 (en) * 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
AU4196099A (en) * 1998-05-21 1999-12-06 Isis Pharmaceuticals, Inc. Long-circulating liposomal compositions
CA2335638A1 (en) * 1998-06-19 1999-12-23 Ronald K. Scheule Cationic amphiphile micellar complexes
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
US20030021792A1 (en) * 2001-06-08 2003-01-30 Roben Paul W. Tissue-specific endothelial membrane proteins
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US20030147944A1 (en) * 1999-12-10 2003-08-07 Mayer Lawrence D Lipid carrier compositions with protected surface reactive functions
WO2001085131A2 (en) * 2000-05-11 2001-11-15 Celator Technologies Inc. Lipid carrier compositions for improved drug retention
JP2005525992A (ja) * 2001-06-25 2005-09-02 イサム・リサーチ・デベロツプメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシテイ・オブ・エルサレム 生物学的物質を充填した小胞の調製法およびそれらの様々な使用
ES2387886T3 (es) * 2001-11-13 2012-10-03 Celator Pharmaceuticals, Inc. Composiciones que transportan lípidos con una mejor estabilidad sanguínea
JP2006502968A (ja) * 2002-02-21 2006-01-26 ユニヴエルシタ デリ スツディ ディ パヴィア 細菌性コラーゲン結合タンパク質に対して交差反応性のモノクロナール抗体
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ， インク． 細胞内感染を予防及び治療するための吸入システム
AR036316A1 (es) * 2002-08-29 2004-08-25 Monte Verde S A Una composicion farmaceutica de liposomas de tamano pequeno y metodo de preparacion
PT1581236E (pt) * 2002-10-29 2013-12-24 Insmed Inc Libertação prolongada de anti-infecciosos
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
WO2006039369A1 (en) * 2004-09-29 2006-04-13 Alza Corporation Microparticles and nanoparticles containing a lipopolymer
US20070105757A1 (en) * 2005-10-31 2007-05-10 May Thomas B Vancomycin formulations having reduced amount of histamine
EP3067047B1 (de) 2005-12-08 2022-04-20 Insmed Incorporated Antiinfektive zusammensetzungen auf lipidbasis zur behandlung von lungeninfekten
DK2019683T4 (da) 2006-04-25 2022-08-29 Univ California Indgivelse af vækstfaktorer til behandling af CNS-lidelser
US20070259031A1 (en) * 2006-04-26 2007-11-08 The Regents Of The University Of California Compositions and methods for convection enhanced delivery of high molecular weight neurotherapeutics
JP5333970B2 (ja) * 2007-03-20 2013-11-06 国立大学法人大阪大学 心筋梗塞の予防および／または治療薬
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
EP3486653A1 (de) 2007-05-24 2019-05-22 The United States Government as represented by The Department of Veterans Affairs Nutzung des ent2 transporters für die beahndlung von skeletaler muskelerkrankung
WO2011160110A1 (en) * 2010-06-19 2011-12-22 Western University Of Health Sciences Novel formulation of pegylated-liposome encapsulated glycopeptide antibiotics
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
US20140023696A1 (en) * 2012-07-20 2014-01-23 Frederick Timothy Guilford Treatment for idiopathic pulmonary fibrosis
US10124066B2 (en) 2012-11-29 2018-11-13 Insmed Incorporated Stabilized vancomycin formulations
US20140234397A1 (en) * 2013-02-15 2014-08-21 Lou Ann Brown Treatment of klebsiella pneumoniae with liposomally formulated glutathione
US10039716B2 (en) * 2013-03-13 2018-08-07 Mallinckrodt Llc Liposomal cisplatin compositions for cancer therapy
LT3466432T (lt) 2014-05-15 2020-12-28 Insmed Incorporated Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti
US20170281541A1 (en) * 2014-09-05 2017-10-05 The Johns Hopkins University Liposome-based mucus-penetrating particles for mucosal delivery
EP4154915A1 (de) 2014-12-31 2023-03-29 Lantheus Medical Imaging, Inc. Lipidverkapselte gasmikrosphärenzusammensetzungen und zugehörige verfahren
KR20180133527A (ko) 2016-05-04 2018-12-14 랜티우스 메디컬 이메징, 인크. 초음파 조영제의 제조 방법 및 장치
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
US11052158B2 (en) * 2016-08-18 2021-07-06 Troy Bremer Delivery of urea to cells of the macula and retina using liposome constructs
EP3731846A4 (de) * 2017-12-29 2022-03-02 Wayne State University Wirkstoffabgabesysteme zur behandlung von infektionen
EP3773505B1 (de) 2018-03-30 2026-04-29 Insmed Incorporated Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten
JP7449275B2 (ja) 2018-05-02 2024-03-13 インスメッド インコーポレイテッド リポソーム薬物製剤の製造方法
US20220339136A1 (en) * 2019-08-30 2022-10-27 United States Government As Represented By The Department Of Veterans Affairs Liposomal troponoid compound formulations

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US4885172A (en) * 1985-06-26 1989-12-05 The Liposome Company, Inc. Composition for targeting, storing and loading of liposomes
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JPS6376862A (ja) * 1986-09-17 1988-04-07 Nippon Denso Co Ltd 表面硬化層を有するアルミニウム部材
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US4837028A (en) * 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US4920016A (en) * 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
JP2666345B2 (ja) * 1987-04-16 1997-10-22 武田薬品工業株式会社 リポソーム製剤およびその製造法
JPH04234841A (ja) * 1988-07-08 1992-08-24 Mitsubishi Rayon Co Ltd 光学活性化合物及び液晶組成物
GB8824593D0 (en) * 1988-10-20 1988-11-23 Royal Free Hosp School Med Liposomes
US5153000A (en) * 1988-11-22 1992-10-06 Kao Corporation Phosphate, liposome comprising the phosphate as membrane constituent, and cosmetic and liposome preparation comprising the liposome
US4906476A (en) * 1988-12-14 1990-03-06 Liposome Technology, Inc. Novel liposome composition for sustained release of steroidal drugs in lungs
US5079234A (en) * 1989-03-23 1992-01-07 Bristol-Myers Squibb Co. Inhibitors of aminoglycoside nephrotoxicity
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time

Also Published As

Publication number Publication date
WO1993019738A1 (en) 1993-10-14
EP0632719B1 (de) 1996-09-11
DK0632719T3 (da) 1997-09-15
ES2092296T3 (es) 1996-11-16
EP0632719A1 (de) 1995-01-11
DE69304685D1 (de) 1996-10-17
US5843473A (en) 1998-12-01
DE69304685T2 (de) 1997-04-03

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee