ATE14318T1 - ANTAGONIST OF THE ANTIDIURETIC AND/OR VASOPRESSOR EFFECTS OF ARGININE VASOPRESSINE. - Google Patents

ANTAGONIST OF THE ANTIDIURETIC AND/OR VASOPRESSOR EFFECTS OF ARGININE VASOPRESSINE.

Info

Publication number: ATE14318T1
Authority: AT; Austria
Prior art keywords: vasopressine; antidiuretic; antagonist; arginine; vasopressor
Prior art date: 1981-03-24

Application number

AT82301555T

Other languages

German (de)

Inventor

Maurice Manning

Wilbur Henderson Sawyer

Original Assignee

Ohio Med College

Univ Columbia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-24

Filing date

1982-03-24

Publication date

1985-08-15

1981-03-24 Priority claimed from US06/247,008 external-priority patent/US4367225A/en

1981-11-16 Priority claimed from US06/322,071 external-priority patent/US4399125A/en

1982-03-24 Application filed by Ohio Med College, Univ Columbia filed Critical Ohio Med College

1985-08-15 Application granted granted Critical

1985-08-15 Publication of ATE14318T1 publication Critical patent/ATE14318T1/en

Links

JLTCWSBVQSZVLT-CDIPANDDSA-N (2s)-n-[(2s)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4r,7s,10s,13s,16s,19r)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosan Chemical compound NCCCC[C@@H](C(=O)NCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@@H](N)CSSC1.C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 JLTCWSBVQSZVLT-CDIPANDDSA-N 0.000 title 1
239000004475 Arginine Substances 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
230000002686 anti-diuretic effect Effects 0.000 title 1
229940124538 antidiuretic agent Drugs 0.000 title 1
239000003160 antidiuretic agent Substances 0.000 title 1
229940124572 antihypotensive agent Drugs 0.000 title 1
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title 1
230000000694 effects Effects 0.000 title 1
239000005526 vasoconstrictor agent Substances 0.000 title 1

AT82301555T 1981-03-24 1982-03-24 ANTAGONIST OF THE ANTIDIURETIC AND/OR VASOPRESSOR EFFECTS OF ARGININE VASOPRESSINE. ATE14318T1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US06/247,008 US4367225A (en)	1981-03-24	1981-03-24	Novel antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin
US06/322,071 US4399125A (en)	1981-03-24	1981-11-16	Novel antagonists of the antidiuretic action of arginine vasopressin
EP82301555A EP0061356B1 (en)	1981-03-24	1982-03-24	Antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin

Publications (1)

Publication Number	Publication Date
ATE14318T1 true ATE14318T1 (en)	1985-08-15

Family

ID=27225833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT82301555T ATE14318T1 (en)	1981-03-24	1982-03-24	ANTAGONIST OF THE ANTIDIURETIC AND/OR VASOPRESSOR EFFECTS OF ARGININE VASOPRESSINE.

Country Status (1)

Country	Link
AT (1)	ATE14318T1 (en)

1982
- 1982-03-24 AT AT82301555T patent/ATE14318T1/en not_active IP Right Cessation

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Legal Events

Date	Code	Title	Description
1985-11-15	UEP	Publication of translation of european patent specification
1990-12-15	REN	Ceased due to non-payment of the annual fee