ATE143257T1 - Arzneiabgabesystem, verfahren zu dessen herstellung sowie dessen verwendung - Google Patents
Arzneiabgabesystem, verfahren zu dessen herstellung sowie dessen verwendungInfo
- Publication number
- ATE143257T1 ATE143257T1 AT90916175T AT90916175T ATE143257T1 AT E143257 T1 ATE143257 T1 AT E143257T1 AT 90916175 T AT90916175 T AT 90916175T AT 90916175 T AT90916175 T AT 90916175T AT E143257 T1 ATE143257 T1 AT E143257T1
- Authority
- AT
- Austria
- Prior art keywords
- delivery system
- drug delivery
- active substances
- production
- matrix
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 238000012377 drug delivery Methods 0.000 abstract 2
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 230000004931 aggregating effect Effects 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Processing Or Creating Images (AREA)
- Image Processing (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8903503A SE465950B (sv) | 1989-10-23 | 1989-10-23 | Kombination av ett aggregat partikelformat, kristallint eller frystorkat laekemedel med en pseudoplastisk gel foer beredning av ett injicerbart preparat samt foerfarande foer dess framstaellning |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE143257T1 true ATE143257T1 (de) | 1996-10-15 |
Family
ID=20377242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90916175T ATE143257T1 (de) | 1989-10-23 | 1990-10-22 | Arzneiabgabesystem, verfahren zu dessen herstellung sowie dessen verwendung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5614221A (de) |
| EP (1) | EP0497846B1 (de) |
| JP (1) | JP3017801B2 (de) |
| AT (1) | ATE143257T1 (de) |
| AU (1) | AU632634B2 (de) |
| CA (1) | CA2067228C (de) |
| DE (1) | DE69028710T2 (de) |
| SE (1) | SE465950B (de) |
| WO (1) | WO1991005544A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5633001A (en) * | 1993-03-19 | 1997-05-27 | Medinvent | Composition and a method for tissue augmentation |
| US5716631A (en) * | 1995-09-29 | 1998-02-10 | Rdn Therapeutics Inc. | Long acting narcotic analgesics and antagonists |
| CN1126537C (zh) * | 1996-05-23 | 2003-11-05 | 株式会社三养社 | 可局部给药,可生物降解和持续释放的用于治疗牙周炎的药物组合物及其制备方法 |
| JP4642946B2 (ja) * | 1996-12-20 | 2011-03-02 | アルザ コーポレイション | ゲル組成物および方法 |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| US7258869B1 (en) * | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7651703B2 (en) | 1999-10-15 | 2010-01-26 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| US7582311B1 (en) * | 1999-10-15 | 2009-09-01 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| JP4460892B2 (ja) | 2001-06-21 | 2010-05-12 | ジェネンテック インコーポレイテッド | 徐放性組成物 |
| RU2005102604A (ru) * | 2002-07-03 | 2005-09-10 | Перикор Сайенс, Инк. (Us) | Композиция гиалуроновой кислоты и способы применения |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| KR101106510B1 (ko) | 2006-05-30 | 2012-01-20 | 인타르시아 세라퓨틱스 인코포레이티드 | 투피스, 내부채널 삼투압 전달 시스템 유동 조절기 |
| EP2359808B1 (de) | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotisches Verabreichungssystem mit Kolbenanordnung |
| WO2008133908A2 (en) | 2007-04-23 | 2008-11-06 | Intarcia Therapeutics, Inc. | Suspension formulations of insulinotropic peptides and uses thereof |
| CA2691531C (en) | 2007-06-22 | 2016-11-01 | Board Of Regents,The University Of Texas System | Formation of stable submicron peptide or protein particles by thin film freezing |
| CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| EP2376522A4 (de) | 2008-11-16 | 2013-12-25 | Univ Texas | Niederviskose hochkonzentrierte suspensionen |
| RU2547990C2 (ru) | 2009-09-28 | 2015-04-10 | Интарсия Терапьютикс, Инк. | Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| RU2730996C2 (ru) | 2015-06-03 | 2020-08-26 | Интарсия Терапьютикс, Инк. | Системы установки и извлечения имплантата |
| KR102574993B1 (ko) | 2016-05-16 | 2023-09-06 | 인타르시아 세라퓨틱스 인코포레이티드 | 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법 |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| JP7286542B2 (ja) | 2017-01-03 | 2023-06-05 | インターシア セラピューティクス,インコーポレイティド | Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3663685A (en) * | 1968-04-01 | 1972-05-16 | Minnesota Mining & Mfg | Biodegradable radioactive particles |
| US4169804A (en) * | 1976-08-19 | 1979-10-02 | Minnesota Mining And Manufacturing Company | Magnetically responsive composite microparticle |
| US4474752A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
| EP0140255B1 (de) * | 1983-10-14 | 1991-05-15 | Sumitomo Pharmaceuticals Company, Limited | Injektionen mit verzögerter Abgabe |
| US4624665A (en) * | 1984-10-01 | 1986-11-25 | Biotek, Inc. | Method of transdermal drug delivery |
| IT1186766B (it) * | 1985-11-08 | 1987-12-16 | Sclavo Spa | Metodo per la preparazione di immunoglobuline per uso endovenoso |
| DE3684887D1 (de) * | 1985-11-29 | 1992-05-21 | Biomatrix Inc | Arzneistoffabgabesysteme auf basis von hyaluronan, dessen derivaten und salzen sowie verfahren zu deren herstellung. |
| JPS63624A (ja) * | 1986-06-19 | 1988-01-05 | Nec Corp | 正規乱数発生方法 |
| DE3626868A1 (de) * | 1986-08-08 | 1988-02-11 | Bayer Ag | Parenterale loesung |
-
1989
- 1989-10-23 SE SE8903503A patent/SE465950B/sv not_active IP Right Cessation
-
1990
- 1990-10-22 WO PCT/SE1990/000683 patent/WO1991005544A1/en not_active Ceased
- 1990-10-22 CA CA002067228A patent/CA2067228C/en not_active Expired - Lifetime
- 1990-10-22 AU AU66237/90A patent/AU632634B2/en not_active Expired
- 1990-10-22 EP EP90916175A patent/EP0497846B1/de not_active Expired - Lifetime
- 1990-10-22 JP JP2514918A patent/JP3017801B2/ja not_active Expired - Lifetime
- 1990-10-22 AT AT90916175T patent/ATE143257T1/de not_active IP Right Cessation
- 1990-10-22 DE DE69028710T patent/DE69028710T2/de not_active Expired - Lifetime
-
1994
- 1994-11-21 US US08/344,707 patent/US5614221A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2067228A1 (en) | 1991-04-24 |
| CA2067228C (en) | 2002-01-08 |
| AU6623790A (en) | 1991-05-16 |
| EP0497846B1 (de) | 1996-09-25 |
| EP0497846A1 (de) | 1992-08-12 |
| US5614221A (en) | 1997-03-25 |
| DE69028710D1 (de) | 1996-10-31 |
| WO1991005544A1 (en) | 1991-05-02 |
| JPH05503921A (ja) | 1993-06-24 |
| JP3017801B2 (ja) | 2000-03-13 |
| SE8903503L (sv) | 1991-04-24 |
| AU632634B2 (en) | 1993-01-07 |
| DE69028710T2 (de) | 1997-04-17 |
| SE465950B (sv) | 1991-11-25 |
| SE8903503D0 (sv) | 1989-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |