ATE143257T1 - Arzneiabgabesystem, verfahren zu dessen herstellung sowie dessen verwendung - Google Patents
Arzneiabgabesystem, verfahren zu dessen herstellung sowie dessen verwendungInfo
- Publication number
- ATE143257T1 ATE143257T1 AT90916175T AT90916175T ATE143257T1 AT E143257 T1 ATE143257 T1 AT E143257T1 AT 90916175 T AT90916175 T AT 90916175T AT 90916175 T AT90916175 T AT 90916175T AT E143257 T1 ATE143257 T1 AT E143257T1
- Authority
- AT
- Austria
- Prior art keywords
- delivery system
- drug delivery
- active substances
- production
- matrix
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 238000012377 drug delivery Methods 0.000 abstract 2
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 230000004931 aggregating effect Effects 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Processing Or Creating Images (AREA)
- Image Processing (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8903503A SE465950B (sv) | 1989-10-23 | 1989-10-23 | Kombination av ett aggregat partikelformat, kristallint eller frystorkat laekemedel med en pseudoplastisk gel foer beredning av ett injicerbart preparat samt foerfarande foer dess framstaellning |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE143257T1 true ATE143257T1 (de) | 1996-10-15 |
Family
ID=20377242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90916175T ATE143257T1 (de) | 1989-10-23 | 1990-10-22 | Arzneiabgabesystem, verfahren zu dessen herstellung sowie dessen verwendung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5614221A (de) |
| EP (1) | EP0497846B1 (de) |
| JP (1) | JP3017801B2 (de) |
| AT (1) | ATE143257T1 (de) |
| AU (1) | AU632634B2 (de) |
| CA (1) | CA2067228C (de) |
| DE (1) | DE69028710T2 (de) |
| SE (1) | SE465950B (de) |
| WO (1) | WO1991005544A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0784487A1 (de) * | 1993-03-19 | 1997-07-23 | Medinvent | Ein präparat und ein verfahren zur gewebevermehrung |
| US5716631A (en) * | 1995-09-29 | 1998-02-10 | Rdn Therapeutics Inc. | Long acting narcotic analgesics and antagonists |
| US6193994B1 (en) * | 1996-05-23 | 2001-02-27 | Samyang Corporation | Locally administrable, biodegradable and sustained-release pharmaceutical composition for periodontitis and process for preparation thereof |
| ES2256898T3 (es) * | 1996-12-20 | 2006-07-16 | Alza Corporation | Composicion de gel y procedimientos. |
| US7258869B1 (en) * | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| US7651703B2 (en) | 1999-10-15 | 2010-01-26 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| US7582311B1 (en) * | 1999-10-15 | 2009-09-01 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| DK1397155T3 (en) | 2001-06-21 | 2015-12-07 | Genentech Inc | Prolonged release formulation |
| EP1539193A4 (de) * | 2002-07-03 | 2010-05-05 | Pericor Science Inc | Zusammensetzungen von hyaluronsäure und verwendungsverfahren |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2007140416A2 (en) | 2006-05-30 | 2007-12-06 | Intarcia Therapeutics, Inc. | Two-piece, internal-channel osmotic delivery system flow modulator |
| PT2359808E (pt) | 2006-08-09 | 2013-08-28 | Intarcia Therapeutics Inc | Sistemas de entrega osmótica e montagens de pistão |
| ES2402172T3 (es) | 2007-04-23 | 2013-04-29 | Intarcia Therapeutics, Inc | Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos |
| EP2170283B1 (de) | 2007-06-22 | 2019-01-09 | Board of Regents, The University of Texas System | Bildung eines stabilen submikron-peptids oder von proteinteilchen durch dünnfilm-gefrieren |
| WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| JP5711138B2 (ja) | 2008-11-16 | 2015-04-30 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 高濃度の低粘度懸濁液 |
| EP3735944A1 (de) | 2009-09-28 | 2020-11-11 | Intarcia Therapeutics, Inc. | Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| KR102650751B1 (ko) | 2015-06-03 | 2024-03-22 | 인타르시아 세라퓨틱스 인코포레이티드 | 임플란트 배치 및 제거 시스템들 |
| CN109310743A (zh) | 2016-05-16 | 2019-02-05 | 因塔西亚制药公司 | 胰高血糖素受体选择性多肽及其使用方法 |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| AU2018206539A1 (en) | 2017-01-03 | 2019-07-18 | Intarcia Therapeutics, Inc. | Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3663685A (en) * | 1968-04-01 | 1972-05-16 | Minnesota Mining & Mfg | Biodegradable radioactive particles |
| US4169804A (en) * | 1976-08-19 | 1979-10-02 | Minnesota Mining And Manufacturing Company | Magnetically responsive composite microparticle |
| US4474752A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
| DE3484584D1 (de) * | 1983-10-14 | 1991-06-20 | Sumitomo Pharma | Injektionen mit verzoegerter abgabe. |
| US4624665A (en) * | 1984-10-01 | 1986-11-25 | Biotek, Inc. | Method of transdermal drug delivery |
| IT1186766B (it) * | 1985-11-08 | 1987-12-16 | Sclavo Spa | Metodo per la preparazione di immunoglobuline per uso endovenoso |
| DE3684887D1 (de) * | 1985-11-29 | 1992-05-21 | Biomatrix Inc | Arzneistoffabgabesysteme auf basis von hyaluronan, dessen derivaten und salzen sowie verfahren zu deren herstellung. |
| JPS63624A (ja) * | 1986-06-19 | 1988-01-05 | Nec Corp | 正規乱数発生方法 |
| DE3626868A1 (de) * | 1986-08-08 | 1988-02-11 | Bayer Ag | Parenterale loesung |
-
1989
- 1989-10-23 SE SE8903503A patent/SE465950B/sv not_active IP Right Cessation
-
1990
- 1990-10-22 JP JP2514918A patent/JP3017801B2/ja not_active Expired - Lifetime
- 1990-10-22 DE DE69028710T patent/DE69028710T2/de not_active Expired - Lifetime
- 1990-10-22 AT AT90916175T patent/ATE143257T1/de not_active IP Right Cessation
- 1990-10-22 AU AU66237/90A patent/AU632634B2/en not_active Expired
- 1990-10-22 CA CA002067228A patent/CA2067228C/en not_active Expired - Lifetime
- 1990-10-22 EP EP90916175A patent/EP0497846B1/de not_active Expired - Lifetime
- 1990-10-22 WO PCT/SE1990/000683 patent/WO1991005544A1/en not_active Ceased
-
1994
- 1994-11-21 US US08/344,707 patent/US5614221A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69028710T2 (de) | 1997-04-17 |
| EP0497846B1 (de) | 1996-09-25 |
| JP3017801B2 (ja) | 2000-03-13 |
| WO1991005544A1 (en) | 1991-05-02 |
| EP0497846A1 (de) | 1992-08-12 |
| SE465950B (sv) | 1991-11-25 |
| SE8903503L (sv) | 1991-04-24 |
| DE69028710D1 (de) | 1996-10-31 |
| JPH05503921A (ja) | 1993-06-24 |
| CA2067228C (en) | 2002-01-08 |
| AU632634B2 (en) | 1993-01-07 |
| US5614221A (en) | 1997-03-25 |
| SE8903503D0 (sv) | 1989-10-23 |
| CA2067228A1 (en) | 1991-04-24 |
| AU6623790A (en) | 1991-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |