ATE143377T1 - Schimäre immunoglobuline für cd4-rezeptoren - Google Patents

Schimäre immunoglobuline für cd4-rezeptoren

Info

Publication number
ATE143377T1
ATE143377T1 AT91903980T AT91903980T ATE143377T1 AT E143377 T1 ATE143377 T1 AT E143377T1 AT 91903980 T AT91903980 T AT 91903980T AT 91903980 T AT91903980 T AT 91903980T AT E143377 T1 ATE143377 T1 AT E143377T1
Authority
AT
Austria
Prior art keywords
receptors
chimeric immunoglobulins
receptor
human origin
antibodies
Prior art date
Application number
AT91903980T
Other languages
English (en)
Inventor
John Ghrayeb
David M Knight
James E Looney
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23816533&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE143377(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Centocor Inc filed Critical Centocor Inc
Application granted granted Critical
Publication of ATE143377T1 publication Critical patent/ATE143377T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT91903980T 1989-12-27 1990-12-27 Schimäre immunoglobuline für cd4-rezeptoren ATE143377T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45738989A 1989-12-27 1989-12-27

Publications (1)

Publication Number Publication Date
ATE143377T1 true ATE143377T1 (de) 1996-10-15

Family

ID=23816533

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91903980T ATE143377T1 (de) 1989-12-27 1990-12-27 Schimäre immunoglobuline für cd4-rezeptoren

Country Status (6)

Country Link
EP (1) EP0511308B2 (de)
JP (1) JPH05502586A (de)
AT (1) ATE143377T1 (de)
CA (1) CA2070182C (de)
DE (1) DE69028713T3 (de)
WO (1) WO1991010722A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037496B2 (en) 1989-12-27 2006-05-02 Centocor, Inc. Chimeric immunoglobulin for CD4 receptors
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
EP0610447B1 (de) * 1991-10-15 1998-12-16 Btg International Limited VERWENDUNG EINES CDw52-SPEZIFISCHEN ANTIKÖRPERS ZUR BEHANDLUNG VON DURCH T-ZELLEN VERMITTELTEN GELENKENTZÜNDUNGEN
US6270766B1 (en) 1992-10-08 2001-08-07 The Kennedy Institute Of Rheumatology Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
EP0676965B1 (de) * 1992-11-16 2007-07-25 Centocor Inc. Verfahren zur Reduzierung der Immunogenizität der variablen Regionen von Antikörpern
PL320610A1 (en) * 1994-12-07 1997-10-13 Hoffmann La Roche Fragments of monoclonal antibodies of immunosuppressive activity
WO2003086457A2 (en) * 2002-04-08 2003-10-23 The John P. Robarts Research Institute Method of treating or preventing autoimmune disease
AT503889B1 (de) * 2006-07-05 2011-12-15 Star Biotechnologische Forschungs Und Entwicklungsges M B H F Multivalente immunglobuline
CN115197320A (zh) * 2021-04-07 2022-10-18 中美冠科生物技术(太仓)有限公司 新型抗cd4抗体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE122237T1 (de) * 1987-05-29 1995-05-15 Tanox Biosystems Inc Hiv-1 neutralisierende monoklonale antikörper.
CA2051107A1 (en) * 1989-04-25 1990-10-26 William N. Sun Antibodies specific for cd4-binding domain of hiv
EP0394827A1 (de) * 1989-04-26 1990-10-31 F. Hoffmann-La Roche Ag Chimärische CD4-Immunoglobulin-Polypeptide

Also Published As

Publication number Publication date
WO1991010722A2 (en) 1991-07-25
JPH05502586A (ja) 1993-05-13
EP0511308B2 (de) 2003-07-09
EP0511308A1 (de) 1992-11-04
WO1991010722A3 (en) 1991-09-05
CA2070182C (en) 2002-12-24
CA2070182A1 (en) 1991-06-28
EP0511308B1 (de) 1996-09-25
DE69028713T2 (de) 1997-02-06
DE69028713T3 (de) 2004-05-13
DE69028713D1 (de) 1996-10-31

Similar Documents

Publication Publication Date Title
ATE143052T1 (de) Chimärisches murine-mensch-immunoglobulin, spezifisch für tumorassoziertes 17-1a antigen
DE69636748D1 (de) Bispezifischer antikörper zur effektiven behandlung von b-zell lymphomen und zellinien
ES2106195T3 (es) Anticuerpo igg aglicosilado anti cd3.
NL300387I1 (nl) Antilichaam tegen menselijke interleukine-6-receptor
FI963004L (fi) Vasta-aineen muodostumista kiihottavia monoklonaalivasta-aineita
DE69535459D1 (de) Monoklonale antikörper spezifisch gegen vegf-rezeptoren und ihre verwendung
NL300350I1 (nl) Geneesmiddelen met monoclonale antilichamen, die specifiek zijn voor de menselijk epidermale groeifactorreceptor
DE59107756D1 (de) Monoklonale Antikörper gegen Melanom
DE69233125D1 (de) Inhibitorische immunglobulin-polypeptide gegen den pdgf beta-rezeptor
FR2794461B1 (fr) Procede de preparation de nouvelles fractions d'ig humaines possedant une activite immunomodulatrice
DE69028713D1 (de) Schimäre immunoglobuline für cd4-rezeptoren
PT954333E (pt) Receptores soluveis de linfotoxina-beta, anticorpos de receptores de anti-linfotoxina e anticorpos de ligandos de anti-linfotoxina como agentes terapeuticos para o tratamento de doencas imunologicas
DE58907058D1 (de) Monoklonaler Antikörper und seine Verwendung.
DK355483A (da) Monoklonale antistoffer til krydsafstemning af humant vaev
DE3884646D1 (de) Humanes Karcinom-assoziertes Antigen und an dieses Antigen bindende Antikörper.
EP1283217A3 (de) Antikörper gegen den IL-8 Rezeptor und deren therapeutische Verwendungen
SE8800886D0 (sv) Immunoglobulin conjugates
DK69690A (da) Humane anti-rh(d) monoklonale antistoffer
ATE184315T1 (de) Neuartiges endothelzell-molekül, das die bindung von lymphozyten im menschen vermittelt
BR9702101A (pt) Hibridoma e anticorpo monoclonal
CS347090A3 (en) Murine lymphocyte hybridoma tsh-51 producing monoclonal antibody of the class igg 2a against human thyrostimulative hormone
CS347190A3 (en) Murine lymphocyte hybridoma tsh-116 producing monoclonal antibody of the class igg 2a against human thyrostimulative hormone
CS338590A3 (en) Murine lymphocyte hybridoma tsh-61 producing a monoclonal antibody of the igg1 class against human thyreostimulating hormone
IT1194260B (it) Linfochine e anticorpi monoclonali umani