ATE143660T1 - Verfahren zur herstellung eines 4,6- bis(difluormethoxy)-2-alkylthiopyrimidins - Google Patents
Verfahren zur herstellung eines 4,6- bis(difluormethoxy)-2-alkylthiopyrimidinsInfo
- Publication number
- ATE143660T1 ATE143660T1 AT90114191T AT90114191T ATE143660T1 AT E143660 T1 ATE143660 T1 AT E143660T1 AT 90114191 T AT90114191 T AT 90114191T AT 90114191 T AT90114191 T AT 90114191T AT E143660 T1 ATE143660 T1 AT E143660T1
- Authority
- AT
- Austria
- Prior art keywords
- alkylthiopyrimidine
- difluoromethoxy
- bis
- base
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- VOPWNXZWBYDODV-UHFFFAOYSA-N Chlorodifluoromethane Chemical compound FC(F)Cl VOPWNXZWBYDODV-UHFFFAOYSA-N 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1013307A JPH0662588B2 (ja) | 1989-01-24 | 1989-01-24 | 4,6―ビス(ジフルオロメトキシ)―2―メチルチオピリミジンの製造法 |
| EP90114191A EP0468069B1 (de) | 1989-01-24 | 1990-07-24 | Verfahren zur Herstellung eines 4,6-Bis(difluormethoxy)-2-alkylthiopyrimidins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE143660T1 true ATE143660T1 (de) | 1996-10-15 |
Family
ID=40139217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90114191T ATE143660T1 (de) | 1989-01-24 | 1990-07-24 | Verfahren zur herstellung eines 4,6- bis(difluormethoxy)-2-alkylthiopyrimidins |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5071982A (de) |
| EP (1) | EP0468069B1 (de) |
| JP (1) | JPH0662588B2 (de) |
| AT (1) | ATE143660T1 (de) |
| DE (1) | DE69028774T2 (de) |
| ES (1) | ES2094130T3 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2208734C (en) * | 1996-07-24 | 2006-05-30 | Lonza Ag | Process for preparing 4,6-bis(difluoro-methoxy)pyrimidine derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4542216A (en) * | 1984-03-27 | 1985-09-17 | Ciba Geigy Corporation | Process for producing fluoroalkoxyaminopyrimidines |
| US4692524A (en) * | 1986-05-02 | 1987-09-08 | Ciba-Geigy Corporation | Process for the preparation of pyrimidine derivatives |
| US4900827A (en) * | 1988-12-22 | 1990-02-13 | Ciba-Geigy Corporation | Process for the preparation of pyrimidine derivatives |
-
1989
- 1989-01-24 JP JP1013307A patent/JPH0662588B2/ja not_active Expired - Lifetime
-
1990
- 1990-07-24 ES ES90114191T patent/ES2094130T3/es not_active Expired - Lifetime
- 1990-07-24 EP EP90114191A patent/EP0468069B1/de not_active Expired - Lifetime
- 1990-07-24 AT AT90114191T patent/ATE143660T1/de not_active IP Right Cessation
- 1990-07-24 DE DE69028774T patent/DE69028774T2/de not_active Expired - Lifetime
- 1990-07-26 US US07/558,297 patent/US5071982A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2094130T3 (es) | 1997-01-16 |
| EP0468069A1 (de) | 1992-01-29 |
| DE69028774T2 (de) | 1997-02-13 |
| JPH0662588B2 (ja) | 1994-08-17 |
| US5071982A (en) | 1991-12-10 |
| EP0468069B1 (de) | 1996-10-02 |
| JPH02196773A (ja) | 1990-08-03 |
| DE69028774D1 (de) | 1996-11-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE198741T1 (de) | Verfahren zur herstellung von uretdiongruppen aufweisenden polyisocyanaten | |
| ATE162529T1 (de) | Verfahren zur herstellung von verbrückten, chiralen metallocenkatalysatoren des types bisindenyl | |
| DE69123880D1 (de) | Verfahren zur Herstellung von Eicosapentaensäure oder von einem Esterderivat davon | |
| ATE277999T1 (de) | Verfahren zur herstellung von amin- umsetzungsprodukt-teilchen | |
| ATE204283T1 (de) | Verfahren zur herstellung von 2,2- difluorketensilylacetalen und alpha,alpha-difluor-beta -silyloxy-1,3-dioxolan-4-propansäureestern | |
| ATE117994T1 (de) | Verfahren zur herstellung von 2-chlor-5- chlormethylpyridin. | |
| PT86160A (de) | Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren zwischenprodukte dieses verfahrens sowie ein verfahrenzu deren herstellung | |
| DE3854948D1 (de) | Verfahren zur Herstellung von organobimetallischen Verbindungen | |
| ATE116641T1 (de) | Verfahren zur herstellung von uretdiongruppen aufweisenden polyisocyanaten. | |
| ATE114637T1 (de) | Verfahren zur herstellung von antikonvulsanten cyclischen aminosäureverbindungen. | |
| DE69615204D1 (de) | Verfahren zur herstellung von kaliumclavulanat | |
| ATE115542T1 (de) | Verfahren zur herstellung von wäscheweichspülmitteln mit hohem feststoffgehalt benutzend geringen lösungsmittelgehalt und beseitigend nebenreaktionen. | |
| ATE156134T1 (de) | Verfahren zur herstellung von alkylpolyglukosiden | |
| ATE143660T1 (de) | Verfahren zur herstellung eines 4,6- bis(difluormethoxy)-2-alkylthiopyrimidins | |
| ATE244225T1 (de) | Verfahren zur herstellung von chinolinderivaten | |
| DE3855002D1 (de) | Verfahren zur Herstellung von Dodecahydro-3a,6,6,9a-tetramethylnaphto(2,1-b)furan | |
| DE3774954D1 (de) | Verfahren zur herstellung von penemen. | |
| AT384222B (de) | Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren | |
| ATE271057T1 (de) | Verfahren zur herstellung von alendron-säure | |
| ATE71108T1 (de) | Verfahren zur herstellung von 21-hydroxy-20-keto- delta-16-steroiden und in diesem verfahren erhaltene zwischenprodukte. | |
| ATE130608T1 (de) | Verfahren zur herstellung von fluoromethyl substituierten pyridin-carbodithioaten. | |
| ATE233267T1 (de) | Verfahren zur herstellung von 3- vinylcephalosporinen | |
| ATE133409T1 (de) | Verfahren zur herstellung von 2-oxindol-1- carboxamiden | |
| DE59402632D1 (de) | Verfahren zur Herstellung von 3beta-Aminocholansäurederivaten | |
| DE69729631D1 (de) | Verfahren zur herstellung von granisetron |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |