ATE143696T1 - Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung - Google Patents
Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildungInfo
- Publication number
- ATE143696T1 ATE143696T1 AT90103830T AT90103830T ATE143696T1 AT E143696 T1 ATE143696 T1 AT E143696T1 AT 90103830 T AT90103830 T AT 90103830T AT 90103830 T AT90103830 T AT 90103830T AT E143696 T1 ATE143696 T1 AT E143696T1
- Authority
- AT
- Austria
- Prior art keywords
- forming
- oligonucleotides
- double stranded
- pair
- stranded oligonucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
Landscapes
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4890889 | 1989-02-28 | ||
| JP5073889 | 1989-03-01 | ||
| JP26695689A JPH03127999A (ja) | 1989-10-12 | 1989-10-12 | オリゴヌクレオチドの形成方法 |
| JP34313489A JPH037583A (ja) | 1989-02-28 | 1989-12-29 | 部分的二本鎖オリゴヌクレオチド及びオリゴヌクレオチドの形成方法 |
| JP02003338A JP3122106B2 (ja) | 1990-01-12 | 1990-01-12 | 標的核酸の検出方法及びプローブの製造方法 |
| JP2765390A JPH03232489A (ja) | 1990-02-06 | 1990-02-06 | 部分的二本鎖オリゴヌクレオチド及びオリゴヌクレオチドの形成方法 |
| JP2930090A JPH03232490A (ja) | 1990-02-07 | 1990-02-07 | オリゴヌクレオチドの形成方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE143696T1 true ATE143696T1 (de) | 1996-10-15 |
Family
ID=27563223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90103830T ATE143696T1 (de) | 1989-02-28 | 1990-02-27 | Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5830643A (de) |
| EP (1) | EP0385410B1 (de) |
| AT (1) | ATE143696T1 (de) |
| DE (1) | DE69028725T2 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0672185A4 (de) * | 1992-07-17 | 1997-04-23 | Aprogenex Inc | Nukleinsäure-probe und ihre verwendung in nachweis von doppelsträngiger nukleinsäuren. |
| WO1994012632A1 (en) * | 1992-11-27 | 1994-06-09 | University College London | Improvements in nucleic acid synthesis by pcr |
| US6673616B1 (en) * | 1992-12-07 | 2004-01-06 | Third Wave Technologies, Inc. | Methods and compositions for characterizing nucleic acids |
| US6372424B1 (en) * | 1995-08-30 | 2002-04-16 | Third Wave Technologies, Inc | Rapid detection and identification of pathogens |
| US6335160B1 (en) * | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US6406855B1 (en) | 1994-02-17 | 2002-06-18 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US6537776B1 (en) | 1999-06-14 | 2003-03-25 | Diversa Corporation | Synthetic ligation reassembly in directed evolution |
| IL120337A0 (en) * | 1997-02-27 | 1997-06-10 | Gesher Israel Advanced Biotecs | Method for joining DNA fragments |
| IL120339A0 (en) * | 1997-02-27 | 1997-06-10 | Gesher Israel Advanced Biotecs | Improved DNA assembly method |
| IL120338A0 (en) * | 1997-02-27 | 1997-06-10 | Gesher Israel Advanced Biotecs | Single step DNA fragments assembly |
| DE19736591A1 (de) * | 1997-08-22 | 1999-02-25 | Peter Prof Dr Hegemann | Verfahren zum Herstellen von Nukleinsäurepolymeren |
| DK1015576T3 (da) | 1997-09-16 | 2005-08-29 | Egea Biosciences Llc | Fremgangsmåde til fuldstændig kemisk syntese og aggregering af gener og genomer |
| US6670127B2 (en) | 1997-09-16 | 2003-12-30 | Egea Biosciences, Inc. | Method for assembly of a polynucleotide encoding a target polypeptide |
| JP2002525590A (ja) | 1998-08-28 | 2002-08-13 | フェビット フェラリウス バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング | 分析物測定法のための支持体および該支持体を製造する方法 |
| JP2002536977A (ja) | 1999-02-19 | 2002-11-05 | フェビット フェラリウス バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング | ポリマーの製法 |
| PT1385950E (pt) | 2001-01-19 | 2008-08-12 | Centocor Inc | Montagem dirigida por computador de um polinucleótido que codifica um polipéptido alvo |
| DE10164197A1 (de) * | 2001-04-12 | 2003-07-17 | Vladimir M Mirsky | Steuerbare Verstärkung der Empfindlichkeit beim Hybridisierungsnachweis |
| US7563600B2 (en) | 2002-09-12 | 2009-07-21 | Combimatrix Corporation | Microarray synthesis and assembly of gene-length polynucleotides |
| JP4458327B2 (ja) * | 2003-08-28 | 2010-04-28 | キヤノン株式会社 | 標的物質の定量方法および該方法に用いるプローブ担体 |
| WO2005037850A2 (en) * | 2003-10-15 | 2005-04-28 | Blue Heron Biotechnology, Inc. | Solid phase methods for polynucleotide production |
| JP2006094760A (ja) * | 2004-09-29 | 2006-04-13 | Canon Inc | 細胞のスクリーニング方法および口腔癌細胞検出方法 |
| US8535914B2 (en) * | 2005-01-21 | 2013-09-17 | Canon Kabushiki Kaisha | Probe, probe set and information acquisition method using the same |
| US20090011413A1 (en) * | 2005-12-14 | 2009-01-08 | Canon Kabushiki Kaisha | Method for screening colon cancer cells and gene set used for examination of colon cancer |
| DE102006039479A1 (de) | 2006-08-23 | 2008-03-06 | Febit Biotech Gmbh | Programmierbare Oligonukleotidsynthese |
| WO2010094772A1 (en) | 2009-02-20 | 2010-08-26 | Febit Holding Gmbh | Synthesis of sequence-verified nucleic acids |
| JP5729904B2 (ja) | 2009-06-02 | 2015-06-03 | キヤノン株式会社 | 細胞から蛋白質、dna、rnaを調製する方法 |
| CA2772298A1 (en) * | 2009-08-26 | 2011-03-03 | Research Development Foundation | Methods for creating antibody libraries |
| JP2013537399A (ja) | 2010-04-16 | 2013-10-03 | ゼウス・サイエンティフィック・インコーポレイテッド | 非精製サンプル中の細胞生存能力を決定することにおいて有用な酵素活性を測定するための方法 |
| TWI805996B (zh) | 2013-08-05 | 2023-06-21 | 美商扭轉生物科技有限公司 | 重新合成之基因庫 |
| WO2016126882A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| HK1258869A1 (zh) | 2015-09-18 | 2019-11-22 | Twist Bioscience Corporation | 寡核酸变体文库及其合成 |
| CN108698012A (zh) | 2015-09-22 | 2018-10-23 | 特韦斯特生物科学公司 | 用于核酸合成的柔性基底 |
| CN108603307A (zh) | 2015-12-01 | 2018-09-28 | 特韦斯特生物科学公司 | 功能化表面及其制备 |
| WO2018038772A1 (en) | 2016-08-22 | 2018-03-01 | Twist Bioscience Corporation | De novo synthesized nucleic acid libraries |
| EP3516528B1 (de) | 2016-09-21 | 2025-10-15 | Atlas Data Storage, Inc. | Nukleinsäurebasierte datenspeicherung |
| EP3538668B8 (de) | 2016-11-10 | 2025-04-23 | Talis Biomedical Corporation | Polynukleotide zur verstärkung und detektion von chlamydia trachomatis |
| WO2018112426A1 (en) | 2016-12-16 | 2018-06-21 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| KR20240158370A (ko) | 2017-02-22 | 2024-11-04 | 트위스트 바이오사이언스 코포레이션 | 핵산 기반 데이터 저장 |
| CA3056388A1 (en) | 2017-03-15 | 2018-09-20 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| KR102628876B1 (ko) | 2017-06-12 | 2024-01-23 | 트위스트 바이오사이언스 코포레이션 | 심리스 핵산 어셈블리를 위한 방법 |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| CN111566125A (zh) | 2017-09-11 | 2020-08-21 | 特韦斯特生物科学公司 | Gpcr结合蛋白及其合成 |
| GB2566986A (en) | 2017-09-29 | 2019-04-03 | Evonetix Ltd | Error detection during hybridisation of target double-stranded nucleic acid |
| US10894242B2 (en) | 2017-10-20 | 2021-01-19 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
| EP3735459B1 (de) | 2018-01-04 | 2026-03-04 | Atlas Data Storage, Inc. | Digitale informationsspeicherung auf dna-basis |
| SG11202011467RA (en) | 2018-05-18 | 2020-12-30 | Twist Bioscience Corp | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| CN113692409B (zh) | 2018-12-26 | 2025-01-10 | 特韦斯特生物科学公司 | 高度准确的从头多核苷酸合成 |
| US11492728B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| EP3930753A4 (de) | 2019-02-26 | 2023-03-29 | Twist Bioscience Corporation | Variante nukleinsäurebibliotheken für glp1-rezeptor |
| CA3144644A1 (en) | 2019-06-21 | 2020-12-24 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| EP4464827A3 (de) | 2019-09-23 | 2025-02-26 | Twist Bioscience Corporation | Varianten von nukleinsäurebibliotheken für crth2 |
| CN115023440B (zh) | 2019-09-23 | 2025-09-12 | 特韦斯特生物科学公司 | 结合CD3ε的抗体 |
| US11891662B2 (en) | 2019-12-02 | 2024-02-06 | Talis Biomedical Corporation | Polynucleotides for amplification and detection of human beta actin |
| US12570750B2 (en) | 2019-12-09 | 2026-03-10 | Twist Bioscience Corporation | Antibodies that bind adenosine A2A receptors and methods of use thereof to treat cancer and neurological diseases |
| US12264365B2 (en) | 2020-03-23 | 2025-04-01 | Talis Biomedical Corporation | Polynucleotides for amplification and detection of SARS-CoV-2 |
| EP4669656A1 (de) | 2023-02-23 | 2025-12-31 | Micropep Technologies S.A. | Mikropeptide zur verbesserung der pflanzenimmunität und anwendung davon |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2422956A1 (fr) * | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
| US4711955A (en) * | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| CA1223831A (en) * | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| US4605735A (en) * | 1983-02-14 | 1986-08-12 | Wakunaga Seiyaku Kabushiki Kaisha | Oligonucleotide derivatives |
| SE8303626D0 (sv) * | 1983-06-23 | 1983-06-23 | Kabigen Ab | A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced |
| ATE64956T1 (de) * | 1984-06-14 | 1991-07-15 | Ciba Geigy Ag | Verfahren zur herstellung von thrombininhibitoren. |
| US4734363A (en) * | 1984-11-27 | 1988-03-29 | Molecular Diagnostics, Inc. | Large scale production of DNA probes |
| EP0196762A1 (de) * | 1985-03-29 | 1986-10-08 | Cetus Corporation | Rekombinante Ricinfragmente, diese exprimierende Vektoren und transformierte Wirte, die Modifikation von DNS-Sequenzen und Isolierung von mRNS |
| EP0316018A3 (de) * | 1985-03-29 | 1989-07-26 | Cetus Oncology Corporation | Modifikation von DNS-Sequenzen |
| US4767699A (en) * | 1985-05-02 | 1988-08-30 | Allied Corporation | Diagnostic reagent, kit and method employing polynucleotide displacement, separation, enzymatic cleavage and adenosine phosphate detection |
| US4797355A (en) * | 1985-06-13 | 1989-01-10 | Amgen Inc. | Methods for attaching polynucleotides to supports |
| US4806631A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on solvolyzed nylon supports |
| US4752566A (en) * | 1985-12-17 | 1988-06-21 | Genetics Institute, Inc. | Displacement polynucleotide method and reagent complex employing labeled probe polynucleotide |
| GB8612087D0 (en) * | 1986-05-19 | 1986-06-25 | Ici Plc | Hybridisation probes |
| CA1317535C (en) * | 1987-06-30 | 1993-05-11 | Nanibhushan Dattagupta | Assay of sequences using amplified genes |
| US4963602A (en) * | 1989-11-13 | 1990-10-16 | Hi-Tek Polymers, Inc. | Aqueous epoxy resin-acrylic resin coating compositions containing also phenoxy, novolac and resole resin combination |
-
1990
- 1990-02-27 AT AT90103830T patent/ATE143696T1/de active
- 1990-02-27 DE DE69028725T patent/DE69028725T2/de not_active Expired - Fee Related
- 1990-02-27 EP EP90103830A patent/EP0385410B1/de not_active Expired - Lifetime
-
1992
- 1992-11-10 US US07/974,303 patent/US5830643A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0385410A2 (de) | 1990-09-05 |
| US5830643A (en) | 1998-11-03 |
| EP0385410B1 (de) | 1996-10-02 |
| DE69028725T2 (de) | 1997-03-13 |
| EP0385410A3 (de) | 1991-07-17 |
| DE69028725D1 (de) | 1996-11-07 |
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