ATE143696T1 - Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung - Google Patents

Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung

Info

Publication number
ATE143696T1
ATE143696T1 AT90103830T AT90103830T ATE143696T1 AT E143696 T1 ATE143696 T1 AT E143696T1 AT 90103830 T AT90103830 T AT 90103830T AT 90103830 T AT90103830 T AT 90103830T AT E143696 T1 ATE143696 T1 AT E143696T1
Authority
AT
Austria
Prior art keywords
forming
oligonucleotides
double stranded
pair
stranded oligonucleotide
Prior art date
Application number
AT90103830T
Other languages
English (en)
Inventor
Nobuko Yamamoto
Kinya Kato
Harumi Iwashita
Masanori Sakuranaga
Original Assignee
Canon Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP26695689A external-priority patent/JPH03127999A/ja
Priority claimed from JP34313489A external-priority patent/JPH037583A/ja
Priority claimed from JP02003338A external-priority patent/JP3122106B2/ja
Priority claimed from JP2765390A external-priority patent/JPH03232489A/ja
Priority claimed from JP2930090A external-priority patent/JPH03232490A/ja
Application filed by Canon Kk filed Critical Canon Kk
Application granted granted Critical
Publication of ATE143696T1 publication Critical patent/ATE143696T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA

Landscapes

  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90103830T 1989-02-28 1990-02-27 Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung ATE143696T1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP4890889 1989-02-28
JP5073889 1989-03-01
JP26695689A JPH03127999A (ja) 1989-10-12 1989-10-12 オリゴヌクレオチドの形成方法
JP34313489A JPH037583A (ja) 1989-02-28 1989-12-29 部分的二本鎖オリゴヌクレオチド及びオリゴヌクレオチドの形成方法
JP02003338A JP3122106B2 (ja) 1990-01-12 1990-01-12 標的核酸の検出方法及びプローブの製造方法
JP2765390A JPH03232489A (ja) 1990-02-06 1990-02-06 部分的二本鎖オリゴヌクレオチド及びオリゴヌクレオチドの形成方法
JP2930090A JPH03232490A (ja) 1990-02-07 1990-02-07 オリゴヌクレオチドの形成方法

Publications (1)

Publication Number Publication Date
ATE143696T1 true ATE143696T1 (de) 1996-10-15

Family

ID=27563223

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90103830T ATE143696T1 (de) 1989-02-28 1990-02-27 Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung

Country Status (4)

Country Link
US (1) US5830643A (de)
EP (1) EP0385410B1 (de)
AT (1) ATE143696T1 (de)
DE (1) DE69028725T2 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994002500A1 (en) * 1992-07-17 1994-02-03 Aprogenex, Inc. Oligonucleotide probes and primers for detecting chromosomal translocation
WO1994012632A1 (en) * 1992-11-27 1994-06-09 University College London Improvements in nucleic acid synthesis by pcr
US6372424B1 (en) * 1995-08-30 2002-04-16 Third Wave Technologies, Inc Rapid detection and identification of pathogens
US6673616B1 (en) * 1992-12-07 2004-01-06 Third Wave Technologies, Inc. Methods and compositions for characterizing nucleic acids
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
IL120338A0 (en) * 1997-02-27 1997-06-10 Gesher Israel Advanced Biotecs Single step DNA fragments assembly
IL120337A0 (en) * 1997-02-27 1997-06-10 Gesher Israel Advanced Biotecs Method for joining DNA fragments
IL120339A0 (en) 1997-02-27 1997-06-10 Gesher Israel Advanced Biotecs Improved DNA assembly method
DE19736591A1 (de) * 1997-08-22 1999-02-25 Peter Prof Dr Hegemann Verfahren zum Herstellen von Nukleinsäurepolymeren
PT1015576E (pt) 1997-09-16 2005-09-30 Egea Biosciences Llc Metodo para a sintese quimica completa e montagem de genes e de genomas
US6670127B2 (en) 1997-09-16 2003-12-30 Egea Biosciences, Inc. Method for assembly of a polynucleotide encoding a target polypeptide
EP1115424A1 (de) 1998-08-28 2001-07-18 Febit Ferrarius Biotechnology GmbH Verfahren und messeinrichtung zur bestimmung einer vielzahl von analyten in einer probe
WO2000049142A1 (de) * 1999-02-19 2000-08-24 Febit Ferrarius Biotechnology Gmbh Verfahren zur herstellung von polymeren
EP1385950B1 (de) * 2001-01-19 2008-07-02 Centocor, Inc. Computer vermitteltes assembly von polynucleotiden kodierend für ein zielgerichtetes polypeptide
DE10164197A1 (de) * 2001-04-12 2003-07-17 Vladimir M Mirsky Steuerbare Verstärkung der Empfindlichkeit beim Hybridisierungsnachweis
US7563600B2 (en) 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides
JP4458327B2 (ja) * 2003-08-28 2010-04-28 キヤノン株式会社 標的物質の定量方法および該方法に用いるプローブ担体
JP2007508825A (ja) * 2003-10-15 2007-04-12 ブルー ヘロン バイオテクノロジー インコーポレイテッド ポリヌクレオチド生成のための固相方法
JP2006094760A (ja) * 2004-09-29 2006-04-13 Canon Inc 細胞のスクリーニング方法および口腔癌細胞検出方法
US8535914B2 (en) * 2005-01-21 2013-09-17 Canon Kabushiki Kaisha Probe, probe set and information acquisition method using the same
US20090011413A1 (en) * 2005-12-14 2009-01-08 Canon Kabushiki Kaisha Method for screening colon cancer cells and gene set used for examination of colon cancer
DE102006039479A1 (de) 2006-08-23 2008-03-06 Febit Biotech Gmbh Programmierbare Oligonukleotidsynthese
EP2398915B1 (de) 2009-02-20 2016-08-24 Synthetic Genomics, Inc. Synthese von nukleinsäuren mit verifizierter sequenz
JP5729904B2 (ja) 2009-06-02 2015-06-03 キヤノン株式会社 細胞から蛋白質、ｄｎａ、ｒｎａを調製する方法
CA2772298A1 (en) * 2009-08-26 2011-03-03 Research Development Foundation Methods for creating antibody libraries
US20130196318A1 (en) 2010-04-16 2013-08-01 Shawn Mark O'Hara Methods for measuring enzyme activity useful in determining cell viability in non-purified samples
SG11201600853UA (en) 2013-08-05 2016-03-30 Twist Bioscience Corp De novo synthesized gene libraries
US10669304B2 (en) 2015-02-04 2020-06-02 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
EP3350314A4 (de) 2015-09-18 2019-02-06 Twist Bioscience Corporation Oligonukleinsäurevariantenbibliotheken variante und synthese davon
KR102794025B1 (ko) 2015-09-22 2025-04-09 트위스트 바이오사이언스 코포레이션 핵산 합성을 위한 가요성 기판
CN115920796A (zh) 2015-12-01 2023-04-07 特韦斯特生物科学公司 功能化表面及其制备
EP3500672A4 (de) 2016-08-22 2020-05-20 Twist Bioscience Corporation De-novo-synthetisierte nukleinsäure-bibliotheken
US10417457B2 (en) 2016-09-21 2019-09-17 Twist Bioscience Corporation Nucleic acid based data storage
CN110177887B (zh) 2016-11-10 2024-10-29 达丽斯生物医学公司 用于扩增和检测沙眼衣原体的多核苷酸
GB2573069A (en) 2016-12-16 2019-10-23 Twist Bioscience Corp Variant libraries of the immunological synapse and synthesis thereof
EP4556433A3 (de) 2017-02-22 2025-08-06 Twist Bioscience Corporation Nukleinsäurebasierte datenspeicherung
WO2018170169A1 (en) 2017-03-15 2018-09-20 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
WO2018231872A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
US11407837B2 (en) 2017-09-11 2022-08-09 Twist Bioscience Corporation GPCR binding proteins and synthesis thereof
GB2566986A (en) 2017-09-29 2019-04-03 Evonetix Ltd Error detection during hybridisation of target double-stranded nucleic acid
CN111565834B (zh) 2017-10-20 2022-08-26 特韦斯特生物科学公司 用于多核苷酸合成的加热的纳米孔
KR102804057B1 (ko) 2018-01-04 2025-05-07 트위스트 바이오사이언스 코포레이션 Dna 기반 디지털 정보 저장
CA3100739A1 (en) 2018-05-18 2019-11-21 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
WO2020139871A1 (en) 2018-12-26 2020-07-02 Twist Bioscience Corporation Highly accurate de novo polynucleotide synthesis
JP2022522668A (ja) 2019-02-26 2022-04-20 ツイスト バイオサイエンス コーポレーション 抗体を最適化するための変異体核酸ライブラリ
CN113766930B (zh) 2019-02-26 2025-07-22 特韦斯特生物科学公司 Glp1受体的变异核酸文库
US11332738B2 (en) 2019-06-21 2022-05-17 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
JP2022548783A (ja) 2019-09-23 2022-11-21 ツイスト バイオサイエンス コーポレーション 単一ドメイン抗体のバリアント核酸ライブラリー
EP4034566A4 (de) 2019-09-23 2024-01-24 Twist Bioscience Corporation Variante nukleinsäurebibliotheken für crth2
US11891662B2 (en) 2019-12-02 2024-02-06 Talis Biomedical Corporation Polynucleotides for amplification and detection of human beta actin
BR112022011235A2 (pt) 2019-12-09 2022-12-13 Twist Bioscience Corp Bibliotecas de variantes de ácido nucleico para receptores de adenosina
US11047007B1 (en) 2020-03-23 2021-06-29 Talis Biomedical Corporation Polynucleotides for amplification and detection of SARS-CoV-2
WO2024175780A1 (en) 2023-02-23 2024-08-29 Micropep Technologies S.A. Micropeptides to improve plant immunity and application thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US4605735A (en) * 1983-02-14 1986-08-12 Wakunaga Seiyaku Kabushiki Kaisha Oligonucleotide derivatives
SE8303626D0 (sv) * 1983-06-23 1983-06-23 Kabigen Ab A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced
DE3583361D1 (de) * 1984-06-14 1991-08-08 Ucp Gen Pharma Ag Verfahren zur herstellung von thrombin-inhibitoren.
US4734363A (en) * 1984-11-27 1988-03-29 Molecular Diagnostics, Inc. Large scale production of DNA probes
EP0196762A1 (de) * 1985-03-29 1986-10-08 Cetus Corporation Rekombinante Ricinfragmente, diese exprimierende Vektoren und transformierte Wirte, die Modifikation von DNS-Sequenzen und Isolierung von mRNS
EP0316018A3 (de) * 1985-03-29 1989-07-26 Cetus Oncology Corporation Modifikation von DNS-Sequenzen
US4767699A (en) * 1985-05-02 1988-08-30 Allied Corporation Diagnostic reagent, kit and method employing polynucleotide displacement, separation, enzymatic cleavage and adenosine phosphate detection
US4797355A (en) * 1985-06-13 1989-01-10 Amgen Inc. Methods for attaching polynucleotides to supports
US4806631A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on solvolyzed nylon supports
US4752566A (en) * 1985-12-17 1988-06-21 Genetics Institute, Inc. Displacement polynucleotide method and reagent complex employing labeled probe polynucleotide
GB8612087D0 (en) * 1986-05-19 1986-06-25 Ici Plc Hybridisation probes
CA1317535C (en) * 1987-06-30 1993-05-11 Nanibhushan Dattagupta Assay of sequences using amplified genes
US4963602A (en) * 1989-11-13 1990-10-16 Hi-Tek Polymers, Inc. Aqueous epoxy resin-acrylic resin coating compositions containing also phenoxy, novolac and resole resin combination

Also Published As

Publication number Publication date
EP0385410A2 (de) 1990-09-05
DE69028725D1 (de) 1996-11-07
DE69028725T2 (de) 1997-03-13
EP0385410B1 (de) 1996-10-02
EP0385410A3 (de) 1991-07-17
US5830643A (en) 1998-11-03

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