ATE144527T1 - Verfahren zur reinigung von 3-alpha-7-beta- dihydroxycholansäure - Google Patents

Verfahren zur reinigung von 3-alpha-7-beta- dihydroxycholansäure

Info

Publication number: ATE144527T1
Authority: AT; Austria
Prior art keywords: alpha; beta; purifying; acid; dihydroxycholanic
Prior art date: 1989-03-06

Application number

AT90103426T

Other languages

English (en)

Inventor

Antonio Bonaldi

Egidio Molinari

Original Assignee

Erregierre Ind Chim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-06

Filing date

1990-02-22

Publication date

1996-11-15

1990-02-22 Application filed by Erregierre Ind Chim filed Critical Erregierre Ind Chim

1996-11-15 Application granted granted Critical

1996-11-15 Publication of ATE144527T1 publication Critical patent/ATE144527T1/de

Links

OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
239000003849 aromatic solvent Substances 0.000 abstract 2
SMEROWZSTRWXGI-UHFFFAOYSA-N Lithocholsaeure Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 SMEROWZSTRWXGI-UHFFFAOYSA-N 0.000 abstract 1
239000012043 crude product Substances 0.000 abstract 1
SMEROWZSTRWXGI-HVATVPOCSA-N lithocholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 SMEROWZSTRWXGI-HVATVPOCSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT90103426T 1989-03-06 1990-02-22 Verfahren zur reinigung von 3-alpha-7-beta- dihydroxycholansäure ATE144527T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8919666A IT1228972B (it)	1989-03-06	1989-03-06	Procedimento per la preparazione di acido 3 alfa 7 beta diidrossicolanico di elevata purezza.

Publications (1)

Publication Number	Publication Date
ATE144527T1 true ATE144527T1 (de)	1996-11-15

Family

ID=11160224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90103426T ATE144527T1 (de)	1989-03-06	1990-02-22	Verfahren zur reinigung von 3-alpha-7-beta- dihydroxycholansäure

Country Status (7)

Country	Link
US (1)	US5117017A (de)
EP (1)	EP0386538B1 (de)
JP (1)	JPH02279696A (de)
AT (1)	ATE144527T1 (de)
CA (1)	CA2011273A1 (de)
DE (1)	DE69028938D1 (de)
IT (1)	IT1228972B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100658511B1 (ko) *	2005-12-12	2006-12-19	주식회사 대웅제약	케노데옥시콜린산의 정제 방법
KR100658512B1 (ko) *	2005-12-30	2006-12-19	주식회사 대웅제약	케노데옥시콜린산의 정제 방법
EP2105500A1 (de)	2008-03-26	2009-09-30	Pharmazell GmbH	Neue 12alpha-Hydroxysteroiddehydrogenasen, deren Herstellung und deren Verwendung
EP2333101A1 (de)	2009-12-11	2011-06-15	PharmaZell GmbH	NAD(P)+-Cofaktorregenerierungssystem und dessen Anwendungen
CN103097400B (zh)	2010-05-27	2015-12-16	细胞制药有限公司	新的7α-羟类固醇脱氢酶敲除突变体及其用途
EP2441771A1 (de)	2010-10-13	2012-04-18	PharmaZell GmbH	Neue 12alpha-Hydroxysteroid- dehydrogenase-Mutanten, deren Herstellung deren Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH459997A (de) *	1963-12-05	1968-07-31	Shalom Prof Sarel	Verfahren zur Herstellung von Cardenoliden
US4186143A (en) *	1977-06-20	1980-01-29	Canada Packers Limited	Chenodeoxycholic acid recovery process

1989
- 1989-03-06 IT IT8919666A patent/IT1228972B/it active
1990
- 1990-02-22 DE DE69028938T patent/DE69028938D1/de not_active Expired - Lifetime
- 1990-02-22 EP EP90103426A patent/EP0386538B1/de not_active Expired - Lifetime
- 1990-02-22 AT AT90103426T patent/ATE144527T1/de not_active IP Right Cessation
- 1990-03-01 CA CA002011273A patent/CA2011273A1/en not_active Abandoned
- 1990-03-06 JP JP2052885A patent/JPH02279696A/ja active Pending
1991
- 1991-09-06 US US07/758,513 patent/US5117017A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IT8919666A0 (it)	1989-03-06
US5117017A (en)	1992-05-26
JPH02279696A (ja)	1990-11-15
EP0386538A2 (de)	1990-09-12
DE69028938D1 (de)	1996-11-28
EP0386538A3 (de)	1992-05-20
EP0386538B1 (de)	1996-10-23
IT1228972B (it)	1991-07-11
CA2011273A1 (en)	1990-09-06

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Legal Events

Date	Code	Title	Description
1997-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties