ATE145559T1 - Reinigung von verunreinigtem ioversol mittel kontinuierlicher deionisierung - Google Patents
Reinigung von verunreinigtem ioversol mittel kontinuierlicher deionisierungInfo
- Publication number
- ATE145559T1 ATE145559T1 AT92920635T AT92920635T ATE145559T1 AT E145559 T1 ATE145559 T1 AT E145559T1 AT 92920635 T AT92920635 T AT 92920635T AT 92920635 T AT92920635 T AT 92920635T AT E145559 T1 ATE145559 T1 AT E145559T1
- Authority
- AT
- Austria
- Prior art keywords
- ioversol
- cleaning contaminated
- continuous deionization
- deionization
- continuous
- Prior art date
Links
- 238000002242 deionisation method Methods 0.000 title abstract 2
- AMDBBAQNWSUWGN-UHFFFAOYSA-N Ioversol Chemical class OCCN(C(=O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I AMDBBAQNWSUWGN-UHFFFAOYSA-N 0.000 title 1
- 238000004140 cleaning Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
- Cleaning Implements For Floors, Carpets, Furniture, Walls, And The Like (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/765,605 US5210300A (en) | 1991-09-25 | 1991-09-25 | Purification of crude ioversol using continuous deionization |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE145559T1 true ATE145559T1 (de) | 1996-12-15 |
Family
ID=25073987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92920635T ATE145559T1 (de) | 1991-09-25 | 1992-09-22 | Reinigung von verunreinigtem ioversol mittel kontinuierlicher deionisierung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5210300A (de) |
| EP (1) | EP0646021B1 (de) |
| JP (1) | JPH06511240A (de) |
| AT (1) | ATE145559T1 (de) |
| AU (1) | AU658349B2 (de) |
| CA (1) | CA2116223A1 (de) |
| DE (1) | DE69215540D1 (de) |
| WO (1) | WO1993005820A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811581A (en) * | 1994-08-04 | 1998-09-22 | Dibra S.P.A. | Process for the purification of opacifying contrast agents |
| IT1282653B1 (it) * | 1996-02-20 | 1998-03-31 | Bracco Spa | Dispositivo e metodo per la rigenerazione di letti misti di resine a scambio ionico |
| ES2680019T3 (es) * | 2010-12-21 | 2018-09-03 | Ge Healthcare As | Desalinización de una composición que comprende un agente de contraste |
| FR3084668A1 (fr) | 2018-08-02 | 2020-02-07 | Guerbet | Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol |
| CN117756660B (zh) * | 2024-01-19 | 2026-03-17 | 重庆圣华曦药业股份有限公司 | 一种碘佛醇杂质的去除方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
| US4826673A (en) * | 1985-01-09 | 1989-05-02 | Mallinckrodt, Inc. | Methods and compositions for enhancing magnetic resonance imaging |
| IT1248741B (it) * | 1991-02-26 | 1995-01-26 | Bracco Spa | Processo di concentrazione e di purificazione di composti organici |
| US5160437A (en) * | 1991-12-03 | 1992-11-03 | Mallinckrodt Medical, Inc. | Purification of crude Ioversol using reverse osmosis |
-
1991
- 1991-09-25 US US07/765,605 patent/US5210300A/en not_active Expired - Lifetime
-
1992
- 1992-09-02 US US07/940,270 patent/US5322934A/en not_active Expired - Fee Related
- 1992-09-22 WO PCT/US1992/007932 patent/WO1993005820A1/en not_active Ceased
- 1992-09-22 AU AU26524/92A patent/AU658349B2/en not_active Expired - Fee Related
- 1992-09-22 DE DE69215540T patent/DE69215540D1/de not_active Expired - Lifetime
- 1992-09-22 EP EP92920635A patent/EP0646021B1/de not_active Expired - Lifetime
- 1992-09-22 AT AT92920635T patent/ATE145559T1/de not_active IP Right Cessation
- 1992-09-22 JP JP5506268A patent/JPH06511240A/ja active Pending
- 1992-09-22 CA CA002116223A patent/CA2116223A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US5322934A (en) | 1994-06-21 |
| US5210300A (en) | 1993-05-11 |
| AU2652492A (en) | 1993-04-27 |
| JPH06511240A (ja) | 1994-12-15 |
| EP0646021A1 (de) | 1995-04-05 |
| CA2116223A1 (en) | 1993-04-01 |
| EP0646021A4 (de) | 1994-10-07 |
| DE69215540D1 (de) | 1997-01-09 |
| WO1993005820A1 (en) | 1993-04-01 |
| AU658349B2 (en) | 1995-04-06 |
| EP0646021B1 (de) | 1996-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |