ATE145911T1 - Inositol-phosphat-analog als kalzium- antagonistische substanz - Google Patents

Inositol-phosphat-analog als kalzium- antagonistische substanz

Info

Publication number: ATE145911T1
Authority: AT; Austria
Prior art keywords: inositol phosphate; calcium antagonist; phosphate analog; antagonist substance; substance
Prior art date: 1991-06-26

Application number

AT92110563T

Other languages

English (en)

Inventor

Werner Dr Schiebler

Elke Deckert

Eric Dr Dreef

D Marel Geijs Dr V

Boom Jacques Prof Von

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-26

Filing date

1992-06-23

Publication date

1996-12-15

1992-06-23 Application filed by Hoechst Ag filed Critical Hoechst Ag

1996-12-15 Application granted granted Critical

1996-12-15 Publication of ATE145911T1 publication Critical patent/ATE145911T1/de

Links

229940127291 Calcium channel antagonist Drugs 0.000 title abstract 2
INAPMGSXUVUWAF-GCVPSNMTSA-N [(2r,3s,5r,6r)-2,3,4,5,6-pentahydroxycyclohexyl] dihydrogen phosphate Chemical class OC1[C@H](O)[C@@H](O)C(OP(O)(O)=O)[C@H](O)[C@@H]1O INAPMGSXUVUWAF-GCVPSNMTSA-N 0.000 title 1
239000000480 calcium channel blocker Substances 0.000 title 1
239000000126 substance Substances 0.000 title 1
229910019142 PO4 Inorganic materials 0.000 abstract 2
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
239000010452 phosphate Substances 0.000 abstract 2
208000024172 Cardiovascular disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4081—Esters with cycloaliphatic alcohols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)

AT92110563T 1991-06-26 1992-06-23 Inositol-phosphat-analog als kalzium- antagonistische substanz ATE145911T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP91110546		1991-06-26

Publications (1)

Publication Number	Publication Date
ATE145911T1 true ATE145911T1 (de)	1996-12-15

Family

ID=8206868

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92110563T ATE145911T1 (de)	1991-06-26	1992-06-23	Inositol-phosphat-analog als kalzium- antagonistische substanz

Country Status (11)

Country	Link
US (1)	US5395828A (de)
EP (1)	EP0520372B1 (de)
JP (1)	JP3161813B2 (de)
KR (1)	KR930000527A (de)
AT (1)	ATE145911T1 (de)
CA (1)	CA2072303A1 (de)
DE (1)	DE69215588T2 (de)
DK (1)	DK0520372T3 (de)
ES (1)	ES2095985T3 (de)
GR (1)	GR3022546T3 (de)
HU (2)	HUT64081A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996000586A2 (en) *	1994-06-30	1996-01-11	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Methods for treating cell proliferative disorders by modulating signal transduction
US6716826B2 (en)	2000-05-12	2004-04-06	Rodaris Pharmaceuticals Limited	Compounds and their uses
US6953781B2 (en)	2000-05-12	2005-10-11	Rodaris Pharmaceuticals Limited	Compounds and their uses
US6759390B2 (en)	2000-05-12	2004-07-06	Manuel Martin-Lomas	Compounds and their uses
US6939857B2 (en)	2000-05-12	2005-09-06	Rodaris Pharmaceuticals Limited	Compounds and their uses
AU2002214886A1 (en) *	2000-11-09	2002-05-21	Contrimmune Biotechnology Inc	Therapeutic uses for IP3 receptor-mediated calcium channel modulators

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4515722A (en) *	1982-03-30	1985-05-07	Merck & Co., Inc.	Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
US4474806A (en)	1982-05-10	1984-10-02	Merck & Co., Inc.	Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents
DE3783694T2 (de) *	1986-03-11	1993-05-19	Mitsui Toatsu Chemicals	Verfahren zur herstellung von myoinositolabkoemmlingen.
SE8605063D0 (sv) *	1986-11-26	1986-11-26	Matti Siren	Derivatives of cyclohexane

1992
- 1992-06-23 DE DE69215588T patent/DE69215588T2/de not_active Expired - Lifetime
- 1992-06-23 DK DK92110563.1T patent/DK0520372T3/da active
- 1992-06-23 AT AT92110563T patent/ATE145911T1/de active
- 1992-06-23 EP EP92110563A patent/EP0520372B1/de not_active Expired - Lifetime
- 1992-06-23 ES ES92110563T patent/ES2095985T3/es not_active Expired - Lifetime
- 1992-06-24 HU HU9202103A patent/HUT64081A/hu unknown
- 1992-06-24 US US07/903,485 patent/US5395828A/en not_active Expired - Lifetime
- 1992-06-25 KR KR1019920011075A patent/KR930000527A/ko not_active Abandoned
- 1992-06-25 CA CA002072303A patent/CA2072303A1/en not_active Abandoned
- 1992-06-25 JP JP16740192A patent/JP3161813B2/ja not_active Expired - Lifetime
1995
- 1995-06-28 HU HU95P/P00494P patent/HU211491A9/hu unknown
1997
- 1997-02-12 GR GR970400235T patent/GR3022546T3/el unknown

Also Published As

Publication number	Publication date
JP3161813B2 (ja)	2001-04-25
KR930000527A (ko)	1993-01-15
CA2072303A1 (en)	1992-12-27
ES2095985T3 (es)	1997-03-01
GR3022546T3 (en)	1997-05-31
HU211491A9 (en)	1995-11-28
HUT64081A (en)	1993-11-29
DE69215588T2 (de)	1997-05-15
DE69215588D1 (de)	1997-01-16
HU9202103D0 (en)	1992-10-28
US5395828A (en)	1995-03-07
JPH05213975A (ja)	1993-08-24
EP0520372B1 (de)	1996-12-04
EP0520372A1 (de)	1992-12-30
DK0520372T3 (da)	1997-05-12

Legal Events

Date	Code	Title	Description
1997-06-15	UEP	Publication of translation of european patent specification

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EP0896533A4 (de)	1999-04-28	Pentafluorobenzensulfonamiden und analoge
MX9102407A (es)	1994-05-31	4 arilpiperazinas y 4-arilpiperidinas novedosas.
NO2011026I2 (no)	2012-06-11	Eribulin eller et farmasøytisk akseptabelt salt derav
DK0582788T3 (da)	1999-02-01	7-(Substituerede)-9-[(substitueret glycyl)-amido]-demethyl-6-deoxytetracycliner
EP0486948A3 (en)	1993-08-25	Retroviral protease inhibiting compounds
ATE119774T1 (de)	1995-04-15	Imidazopyridinderivate und ihre verwendung.
NO931917L (no)	1993-11-30	Farmas!ytiske forbindelser
DE69716810D1 (de)	2002-12-12	2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
DE69229442D1 (de)	1999-07-22	Substituierte dibenzooxazepin-verbindungen, pharmazeutische zusammensetzungen und verfahren zur verwendung
DK0409435T3 (da)	1994-11-21	Heteroarylpiperaziner som antipsykotiske midler
SE9100920D0 (sv)	1991-03-27	New active compounds
ATE179169T1 (de)	1999-05-15	Prostaglandinanaloge
ES556864A0 (es)	1987-08-01	Procedimiento para la obtencion de benzopiranos sustituidos.
ZA883444B (de)	1988-11-16
EP0328634A4 (en)	1991-08-21	Pharmaceutical compositions for the treatment of psoriasis
ATE145911T1 (de)	1996-12-15	Inositol-phosphat-analog als kalzium- antagonistische substanz
ES2062389T3 (es)	1994-12-16	Acidos glutaramicos sustituidos y sus derivados.
ES2123728T3 (es)	1999-01-16	Derivados de pirrolo-pirazina de actividad 5-ht3.
GB9202139D0 (en)	1992-03-18	Improvements in or relating to organic compounds
DK656889A (da)	1990-06-24	Azabicykliske derivater
NO995132D0 (no)	1999-10-21	Fremgangsmåte for reduksjon av fibrinogen
ATE100710T1 (de)	1994-02-15	Eperisone als hypotonikum.
DE69707793D1 (de)	2001-12-06	Alkynylaminosäure Derivate und ihre Verwendung als pharmazeutische Verbindungen