ATE146080T1 - Synergistische zusammensetzungen - Google Patents
Synergistische zusammensetzungenInfo
- Publication number
- ATE146080T1 ATE146080T1 AT91906872T AT91906872T ATE146080T1 AT E146080 T1 ATE146080 T1 AT E146080T1 AT 91906872 T AT91906872 T AT 91906872T AT 91906872 T AT91906872 T AT 91906872T AT E146080 T1 ATE146080 T1 AT E146080T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- synergistic compositions
- reductase
- alpha
- steroid
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000002195 synergetic effect Effects 0.000 title 1
- 108010029908 3-oxo-5-alpha-steroid 4-dehydrogenase Proteins 0.000 abstract 2
- 102000001779 3-oxo-5-alpha-steroid 4-dehydrogenase Human genes 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 230000002860 competitive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000036967 uncompetitive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909006023A GB9006023D0 (en) | 1990-03-16 | 1990-03-16 | Synergistic compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE146080T1 true ATE146080T1 (de) | 1996-12-15 |
Family
ID=10672772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91906872T ATE146080T1 (de) | 1990-03-16 | 1991-03-13 | Synergistische zusammensetzungen |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0521080B1 (de) |
| JP (1) | JPH05506019A (de) |
| AT (1) | ATE146080T1 (de) |
| AU (1) | AU648551B2 (de) |
| CA (1) | CA2076530A1 (de) |
| DE (1) | DE69123573T2 (de) |
| GB (1) | GB9006023D0 (de) |
| WO (1) | WO1991013550A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ283894A3 (en) * | 1992-05-20 | 1995-09-13 | Merck & Co Inc | 7beta-substituted 4-aza-5alpha-cholestanones, their use for the preparation of pharmaceutical preparations and pharmaceutical compositions containing thereof |
| EP0717618B1 (de) * | 1993-09-03 | 2002-11-06 | Smithkline Beecham Corporation | Stabilisierte tablettenformulierung |
| IL111467A0 (en) * | 1993-11-12 | 1994-12-29 | Merck & Co Inc | Pharmaceutical compositions comprising 7 beta -substituted -4-aza 5 alpha -cholestan-3-ones and 5 alpha reductase 1 inhibitors |
| GB9411103D0 (en) * | 1994-06-03 | 1994-07-27 | Smithkline Beecham Corp | Compounds |
| US5543417A (en) * | 1994-10-21 | 1996-08-06 | Merck & Co., Inc. | Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase inhibitors with anti-bacterial, keratolytic, or anti-inflammatory agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4317817A (en) * | 1979-08-27 | 1982-03-02 | Richardson-Merrell Inc. | Novel steroid 5α-reductase inhibitors |
| US4684635A (en) * | 1984-05-11 | 1987-08-04 | Norman Orentreich | Compositions and methods for inhibiting the action of androgens |
-
1990
- 1990-03-16 GB GB909006023A patent/GB9006023D0/en active Pending
-
1991
- 1991-03-13 DE DE69123573T patent/DE69123573T2/de not_active Expired - Fee Related
- 1991-03-13 JP JP91507241A patent/JPH05506019A/ja active Pending
- 1991-03-13 CA CA002076530A patent/CA2076530A1/en not_active Abandoned
- 1991-03-13 AU AU75738/91A patent/AU648551B2/en not_active Ceased
- 1991-03-13 EP EP91906872A patent/EP0521080B1/de not_active Expired - Lifetime
- 1991-03-13 WO PCT/US1991/001740 patent/WO1991013550A1/en not_active Ceased
- 1991-03-13 AT AT91906872T patent/ATE146080T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2076530A1 (en) | 1991-09-17 |
| HK1006542A1 (en) | 1999-03-05 |
| JPH05506019A (ja) | 1993-09-02 |
| DE69123573T2 (de) | 1997-04-17 |
| AU648551B2 (en) | 1994-04-28 |
| EP0521080A1 (de) | 1993-01-07 |
| DE69123573D1 (de) | 1997-01-23 |
| AU7573891A (en) | 1991-10-10 |
| EP0521080B1 (de) | 1996-12-11 |
| EP0521080A4 (en) | 1993-11-24 |
| WO1991013550A1 (en) | 1991-09-19 |
| GB9006023D0 (en) | 1990-05-09 |
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