ATE146879T1 - Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen. - Google Patents
Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen.Info
- Publication number
- ATE146879T1 ATE146879T1 AT91904565T AT91904565T ATE146879T1 AT E146879 T1 ATE146879 T1 AT E146879T1 AT 91904565 T AT91904565 T AT 91904565T AT 91904565 T AT91904565 T AT 91904565T AT E146879 T1 ATE146879 T1 AT E146879T1
- Authority
- AT
- Austria
- Prior art keywords
- flow cytometer
- microbead
- microbeads
- channels
- reference standard
- Prior art date
Links
- 239000011325 microbead Substances 0.000 title abstract 7
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1012—Calibrating particle analysers; References therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1012—Calibrating particle analysers; References therefor
- G01N2015/1014—Constitution of reference particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/465,792 US5073497A (en) | 1989-06-30 | 1990-01-16 | Microbead reference standard and method of adjusting a flow cytometer to obtain reproducible results using the microbeads |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE146879T1 true ATE146879T1 (de) | 1997-01-15 |
Family
ID=23849170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91904565T ATE146879T1 (de) | 1990-01-16 | 1991-01-10 | Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5073497A (de) |
| EP (1) | EP0511314B1 (de) |
| AT (1) | ATE146879T1 (de) |
| DE (1) | DE69123835T2 (de) |
| WO (1) | WO1991010893A1 (de) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993002360A1 (en) * | 1991-07-16 | 1993-02-04 | Transmed Biotech Incorporated | Methods and compositions for simultaneous analysis of multiple analytes |
| WO1994002642A1 (en) * | 1992-07-17 | 1994-02-03 | Aprogenex, Inc. | Background-reducing compounds for probe-mediated in-situ fluorimetric assays |
| DE69326731T2 (de) * | 1992-09-04 | 2000-05-18 | Becton Dickinson And Co., Franklin Lakes | Kontroll-Teilchen für die Zellzählung und Instrumentenlinearität |
| US6613535B1 (en) * | 1992-10-29 | 2003-09-02 | Becton, Dickinson Andcompany | HLA-B27 assay |
| US5288642A (en) * | 1992-12-09 | 1994-02-22 | Flockton Analytical Management Inc. | Shelf-stable milk calibration standards |
| FR2707658B1 (fr) * | 1993-07-12 | 1995-11-24 | Prolabo Sa | Latex fluorescent comportant au moins deux fluorochromes, procédé d'obtention et application dudit latex comme marqueur, notamment en biologie. |
| AU6295794A (en) * | 1994-01-14 | 1995-08-01 | Aprogenex, Inc. | Background-reducing compounds for probe-mediated (in-situ) fluorimetric assays |
| US5891734A (en) * | 1994-08-01 | 1999-04-06 | Abbott Laboratories | Method for performing automated analysis |
| US5656499A (en) * | 1994-08-01 | 1997-08-12 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
| US5631165A (en) * | 1994-08-01 | 1997-05-20 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
| JP3875754B2 (ja) * | 1995-11-17 | 2007-01-31 | シスメックス株式会社 | フローサイトメータ用標準液 |
| US5837547A (en) * | 1995-12-27 | 1998-11-17 | Caribbean Microparticles Corporation | Flow cytometer calibration method |
| US5747349A (en) * | 1996-03-20 | 1998-05-05 | University Of Washington | Fluorescent reporter beads for fluid analysis |
| US6449562B1 (en) | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| US6074879A (en) * | 1997-06-23 | 2000-06-13 | Bayer Corporation | Synthetic polymer particles for use as standards and calibrators in flow cytometry |
| US6214563B1 (en) | 1997-08-01 | 2001-04-10 | Aurora Biosciences Corporation | Photon reducing agents for reducing undesired light emission in assays |
| US6221612B1 (en) * | 1997-08-01 | 2001-04-24 | Aurora Biosciences Corporation | Photon reducing agents for use in fluorescence assays |
| US6200762B1 (en) | 1997-08-01 | 2001-03-13 | Aurora Biosciences Corporation | Photon reducing agents and compositions for fluorescence assays |
| DK176174B1 (da) | 1997-09-12 | 2006-11-20 | Foss Analytical As | Fremgangsmåde og standardkit til at kontrollere funktionen af et flowcytometer, samt apparat til udövelse af fremgangsmåden |
| US6897031B1 (en) * | 1998-04-17 | 2005-05-24 | Rigel Pharmaceuticals, Inc. | Multiparameter FACS assays to detect alterations in exocytosis |
| WO2000051814A1 (en) * | 1999-03-05 | 2000-09-08 | Bio-Rad Laboratories, Inc. | Simultaneous analysis of an analyte and an interfering substance using flow cytometry |
| US7098042B2 (en) * | 1999-09-02 | 2006-08-29 | Btf Pty Ltd. | Internal quality control |
| AU2001265419B2 (en) * | 2000-06-02 | 2007-03-01 | Cytometry Applications, Inc. | No wash bead assay, kit and procedure |
| AU2001290197A1 (en) * | 2000-10-05 | 2002-04-15 | Yoram Palti | Geometrically efficient particle agglutination, particularly to detect low affinity binding |
| US7479630B2 (en) | 2004-03-25 | 2009-01-20 | Bandura Dmitry R | Method and apparatus for flow cytometry linked with elemental analysis |
| DK2184346T3 (en) | 2001-09-06 | 2017-06-26 | Rapid Micro Biosystems Inc | Rapid detection of replicating cells |
| US20040058333A1 (en) * | 2002-09-23 | 2004-03-25 | Bell Michael L. | Assay products and procedures |
| US7326573B2 (en) * | 2003-01-10 | 2008-02-05 | Beckman Coulter, Inc. | Assay procedures and apparatus |
| KR100576364B1 (ko) * | 2003-11-21 | 2006-05-03 | 삼성전자주식회사 | 시편 검사장치의 기준값설정장치 및 이를 이용한 기준값설정방법 |
| CN101528912B (zh) | 2005-09-26 | 2014-08-27 | 快速微型生物系统公司 | 包含生长培养基的盒 |
| WO2008058004A2 (en) | 2006-11-02 | 2008-05-15 | Winnik Mitchell A | Particles containing detectable elemental code |
| CN102224410B (zh) | 2008-09-24 | 2017-02-08 | 施特劳斯控股公司 | 用于测试分析物的成像分析仪 |
| US8187885B2 (en) * | 2009-05-07 | 2012-05-29 | Nodality, Inc. | Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument |
| HUE049333T2 (hu) | 2011-11-07 | 2020-09-28 | Rapid Micro Biosystems Inc | Kazetta sterilitási vizsgálathoz |
| EP2839021B1 (de) | 2012-04-16 | 2022-02-23 | Rapid Micro Biosystems, Inc. | Zellkultivierungsvorrichtung |
| AU2014228537A1 (en) | 2013-03-15 | 2015-08-20 | Beckman Coulter, Inc. | Systems and methods for panel design in flow cytometry |
| FR3022347B1 (fr) * | 2014-06-17 | 2018-01-12 | Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris | Particules liquides biomimetiques, procede et dispositif de mesure en cytometrie en flux |
| JP7347849B2 (ja) | 2018-04-19 | 2023-09-20 | ファースト ライト ダイアグノスティクス, インコーポレイテッド | 標的の検出 |
| EP3803339B1 (de) * | 2018-06-08 | 2025-02-19 | Revvity Health Sciences, Inc. | Kalibrierung von multispektralen analysesystemen |
| JP7659314B2 (ja) | 2018-10-04 | 2025-04-09 | ファースト ライト ダイアグノスティックス, インコーポレイテッド | 分析機器 |
| WO2024258932A1 (en) * | 2023-06-12 | 2024-12-19 | The General Hospital Corporation | Spectrally distinct microbeads using laser particles |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035316A (en) * | 1975-11-24 | 1977-07-12 | California Institute Of Technology | Cell specific, variable density, polymer microspheres |
| US4162282A (en) * | 1976-04-22 | 1979-07-24 | Coulter Electronics, Inc. | Method for producing uniform particles |
| US4157323A (en) * | 1976-06-09 | 1979-06-05 | California Institute Of Technology | Metal containing polymeric functional microspheres |
| US4102282A (en) * | 1977-04-01 | 1978-07-25 | Union Special Corporation | Metering device for sewing machines |
| US4247434A (en) * | 1978-12-29 | 1981-01-27 | Lovelace Alan M Administrator | Process for preparation of large-particle-size monodisperse |
| US4254096A (en) * | 1979-10-04 | 1981-03-03 | Bio-Rad Laboratories, Inc. | Reagent combination for solid phase immunofluorescent assay |
| CA1177751A (en) * | 1980-12-09 | 1984-11-13 | Shuntaro Hosaka | Immunoparticles and process for preparing same |
| US4438239A (en) * | 1981-03-30 | 1984-03-20 | California Institute Of Technology | Microsphere coated substrate containing reactive aldehyde groups |
| US4511662A (en) * | 1982-06-18 | 1985-04-16 | Bio-Rad Laboratories, Inc. | Simultaneous assay for T and B lymphocyte populations and subpopulations |
| US4552633A (en) * | 1982-09-29 | 1985-11-12 | Japan Atomic Energy Research Institute | Fine particulate for use in clinical testing and a process for producing thereof |
| DE3238353A1 (de) * | 1982-10-15 | 1984-04-19 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur simultanen quantitativen bestimmung der blutzellen und reagenz hierfuer |
| US4605630A (en) * | 1983-07-27 | 1986-08-12 | Cooper Lipotech Inc. | Large-liposome agglutination reagent and method |
| US4698262A (en) * | 1984-04-27 | 1987-10-06 | Becton, Dickinson And Company | Fluorescently labeled microbeads |
| US4699828A (en) * | 1984-04-27 | 1987-10-13 | Becton, Dickinson And Company | Fluorescently labeled microbeads |
| US4699826A (en) * | 1984-04-27 | 1987-10-13 | Becton, Dickinson And Company | Fluorescently labeled microbeads |
| US4609689A (en) * | 1984-04-27 | 1986-09-02 | Becton, Dickinson And Company | Method of preparing fluorescently labeled microbeads |
| US4665020A (en) * | 1984-05-30 | 1987-05-12 | United States Department Of Energy | Flow cytometer measurement of binding assays |
| US5093234A (en) * | 1984-12-24 | 1992-03-03 | Caribbean Microparticles Corporation | Method of aligning, compensating, and calibrating a flow cytometer for analysis of samples, and microbead standards kit therefor |
| US4774189A (en) * | 1984-12-24 | 1988-09-27 | Flow Cytometry Standards Corp. | Fluorescent calibration microbeads simulating stained cells |
| US4767206A (en) * | 1984-12-24 | 1988-08-30 | Flow Cytometry Standards Corporation | Calibration method for flow cytometry using fluorescent microbeads and synthesis thereof |
| US4918004A (en) * | 1984-12-24 | 1990-04-17 | Caribbean Microparticles Corporation | Method of calibrating a flow cytometer or fluorescence microscope for quantitating binding antibodies on a selected sample, and microbead calibration kit therefor |
| US4857451A (en) * | 1984-12-24 | 1989-08-15 | Flow Cytometry Standards Corporation | Method of compensating and calibrating a flow cytometer, and microbead standards kit therefor |
| US4828984A (en) * | 1986-04-11 | 1989-05-09 | Flow Cytometry Standards Corporation | Composition, synthesis and use of simulated cells |
| NO860171L (no) * | 1985-01-30 | 1986-07-31 | Japan Synthetic Rubber Co Ltd | Fremgangsmaate for fremstilling av store polymerpartikler. |
| US4714682A (en) * | 1985-12-11 | 1987-12-22 | Flow Cytometry Standards Corporation | Fluorescent calibration microbeads simulating stained cells |
| US4868126A (en) * | 1985-12-11 | 1989-09-19 | Flow Cytometry Standards Corporation | Method of calibrating a fluorescent microscope using fluorescent calibration microbeads simulating stained cells |
-
1990
- 1990-01-16 US US07/465,792 patent/US5073497A/en not_active Expired - Lifetime
-
1991
- 1991-01-10 WO PCT/US1991/000221 patent/WO1991010893A1/en not_active Ceased
- 1991-01-10 EP EP91904565A patent/EP0511314B1/de not_active Expired - Lifetime
- 1991-01-10 DE DE69123835T patent/DE69123835T2/de not_active Expired - Fee Related
- 1991-01-10 AT AT91904565T patent/ATE146879T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0511314B1 (de) | 1996-12-27 |
| WO1991010893A1 (en) | 1991-07-25 |
| DE69123835D1 (de) | 1997-02-06 |
| EP0511314A1 (de) | 1992-11-04 |
| DE69123835T2 (de) | 1997-04-10 |
| US5073497A (en) | 1991-12-17 |
| EP0511314A4 (en) | 1993-08-04 |
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