ATE146879T1 - Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen. - Google Patents

Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen.

Info

Publication number
ATE146879T1
ATE146879T1 AT91904565T AT91904565T ATE146879T1 AT E146879 T1 ATE146879 T1 AT E146879T1 AT 91904565 T AT91904565 T AT 91904565T AT 91904565 T AT91904565 T AT 91904565T AT E146879 T1 ATE146879 T1 AT E146879T1
Authority
AT
Austria
Prior art keywords
flow cytometer
microbead
microbeads
channels
reference standard
Prior art date
Application number
AT91904565T
Other languages
English (en)
Inventor
Abraham Schwartz
Original Assignee
Caribbean Microparticles Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caribbean Microparticles Corp filed Critical Caribbean Microparticles Corp
Application granted granted Critical
Publication of ATE146879T1 publication Critical patent/ATE146879T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/1012Calibrating particle analysers; References therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/1012Calibrating particle analysers; References therefor
    • G01N2015/1014Constitution of reference particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT91904565T 1990-01-16 1991-01-10 Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen. ATE146879T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/465,792 US5073497A (en) 1989-06-30 1990-01-16 Microbead reference standard and method of adjusting a flow cytometer to obtain reproducible results using the microbeads

Publications (1)

Publication Number Publication Date
ATE146879T1 true ATE146879T1 (de) 1997-01-15

Family

ID=23849170

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91904565T ATE146879T1 (de) 1990-01-16 1991-01-10 Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen.

Country Status (5)

Country Link
US (1) US5073497A (de)
EP (1) EP0511314B1 (de)
AT (1) ATE146879T1 (de)
DE (1) DE69123835T2 (de)
WO (1) WO1991010893A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993002360A1 (en) * 1991-07-16 1993-02-04 Transmed Biotech Incorporated Methods and compositions for simultaneous analysis of multiple analytes
WO1994002642A1 (en) * 1992-07-17 1994-02-03 Aprogenex, Inc. Background-reducing compounds for probe-mediated in-situ fluorimetric assays
DE69326731T2 (de) * 1992-09-04 2000-05-18 Becton Dickinson And Co., Franklin Lakes Kontroll-Teilchen für die Zellzählung und Instrumentenlinearität
US6613535B1 (en) * 1992-10-29 2003-09-02 Becton, Dickinson Andcompany HLA-B27 assay
US5288642A (en) * 1992-12-09 1994-02-22 Flockton Analytical Management Inc. Shelf-stable milk calibration standards
FR2707658B1 (fr) * 1993-07-12 1995-11-24 Prolabo Sa Latex fluorescent comportant au moins deux fluorochromes, procédé d'obtention et application dudit latex comme marqueur, notamment en biologie.
AU6295794A (en) * 1994-01-14 1995-08-01 Aprogenex, Inc. Background-reducing compounds for probe-mediated (in-situ) fluorimetric assays
US5891734A (en) * 1994-08-01 1999-04-06 Abbott Laboratories Method for performing automated analysis
US5656499A (en) * 1994-08-01 1997-08-12 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5631165A (en) * 1994-08-01 1997-05-20 Abbott Laboratories Method for performing automated hematology and cytometry analysis
JP3875754B2 (ja) * 1995-11-17 2007-01-31 シスメックス株式会社 フローサイトメータ用標準液
US5837547A (en) * 1995-12-27 1998-11-17 Caribbean Microparticles Corporation Flow cytometer calibration method
US5747349A (en) * 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US6074879A (en) * 1997-06-23 2000-06-13 Bayer Corporation Synthetic polymer particles for use as standards and calibrators in flow cytometry
US6214563B1 (en) 1997-08-01 2001-04-10 Aurora Biosciences Corporation Photon reducing agents for reducing undesired light emission in assays
US6221612B1 (en) * 1997-08-01 2001-04-24 Aurora Biosciences Corporation Photon reducing agents for use in fluorescence assays
US6200762B1 (en) 1997-08-01 2001-03-13 Aurora Biosciences Corporation Photon reducing agents and compositions for fluorescence assays
DK176174B1 (da) 1997-09-12 2006-11-20 Foss Analytical As Fremgangsmåde og standardkit til at kontrollere funktionen af et flowcytometer, samt apparat til udövelse af fremgangsmåden
US6897031B1 (en) * 1998-04-17 2005-05-24 Rigel Pharmaceuticals, Inc. Multiparameter FACS assays to detect alterations in exocytosis
WO2000051814A1 (en) * 1999-03-05 2000-09-08 Bio-Rad Laboratories, Inc. Simultaneous analysis of an analyte and an interfering substance using flow cytometry
US7098042B2 (en) * 1999-09-02 2006-08-29 Btf Pty Ltd. Internal quality control
AU2001265419B2 (en) * 2000-06-02 2007-03-01 Cytometry Applications, Inc. No wash bead assay, kit and procedure
AU2001290197A1 (en) * 2000-10-05 2002-04-15 Yoram Palti Geometrically efficient particle agglutination, particularly to detect low affinity binding
US7479630B2 (en) 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
DK2184346T3 (en) 2001-09-06 2017-06-26 Rapid Micro Biosystems Inc Rapid detection of replicating cells
US20040058333A1 (en) * 2002-09-23 2004-03-25 Bell Michael L. Assay products and procedures
US7326573B2 (en) * 2003-01-10 2008-02-05 Beckman Coulter, Inc. Assay procedures and apparatus
KR100576364B1 (ko) * 2003-11-21 2006-05-03 삼성전자주식회사 시편 검사장치의 기준값설정장치 및 이를 이용한 기준값설정방법
CN101528912B (zh) 2005-09-26 2014-08-27 快速微型生物系统公司 包含生长培养基的盒
WO2008058004A2 (en) 2006-11-02 2008-05-15 Winnik Mitchell A Particles containing detectable elemental code
CN102224410B (zh) 2008-09-24 2017-02-08 施特劳斯控股公司 用于测试分析物的成像分析仪
US8187885B2 (en) * 2009-05-07 2012-05-29 Nodality, Inc. Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument
HUE049333T2 (hu) 2011-11-07 2020-09-28 Rapid Micro Biosystems Inc Kazetta sterilitási vizsgálathoz
EP2839021B1 (de) 2012-04-16 2022-02-23 Rapid Micro Biosystems, Inc. Zellkultivierungsvorrichtung
AU2014228537A1 (en) 2013-03-15 2015-08-20 Beckman Coulter, Inc. Systems and methods for panel design in flow cytometry
FR3022347B1 (fr) * 2014-06-17 2018-01-12 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris Particules liquides biomimetiques, procede et dispositif de mesure en cytometrie en flux
JP7347849B2 (ja) 2018-04-19 2023-09-20 ファースト ライト ダイアグノスティクス, インコーポレイテッド 標的の検出
EP3803339B1 (de) * 2018-06-08 2025-02-19 Revvity Health Sciences, Inc. Kalibrierung von multispektralen analysesystemen
JP7659314B2 (ja) 2018-10-04 2025-04-09 ファースト ライト ダイアグノスティックス, インコーポレイテッド 分析機器
WO2024258932A1 (en) * 2023-06-12 2024-12-19 The General Hospital Corporation Spectrally distinct microbeads using laser particles

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035316A (en) * 1975-11-24 1977-07-12 California Institute Of Technology Cell specific, variable density, polymer microspheres
US4162282A (en) * 1976-04-22 1979-07-24 Coulter Electronics, Inc. Method for producing uniform particles
US4157323A (en) * 1976-06-09 1979-06-05 California Institute Of Technology Metal containing polymeric functional microspheres
US4102282A (en) * 1977-04-01 1978-07-25 Union Special Corporation Metering device for sewing machines
US4247434A (en) * 1978-12-29 1981-01-27 Lovelace Alan M Administrator Process for preparation of large-particle-size monodisperse
US4254096A (en) * 1979-10-04 1981-03-03 Bio-Rad Laboratories, Inc. Reagent combination for solid phase immunofluorescent assay
CA1177751A (en) * 1980-12-09 1984-11-13 Shuntaro Hosaka Immunoparticles and process for preparing same
US4438239A (en) * 1981-03-30 1984-03-20 California Institute Of Technology Microsphere coated substrate containing reactive aldehyde groups
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
US4552633A (en) * 1982-09-29 1985-11-12 Japan Atomic Energy Research Institute Fine particulate for use in clinical testing and a process for producing thereof
DE3238353A1 (de) * 1982-10-15 1984-04-19 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verfahren zur simultanen quantitativen bestimmung der blutzellen und reagenz hierfuer
US4605630A (en) * 1983-07-27 1986-08-12 Cooper Lipotech Inc. Large-liposome agglutination reagent and method
US4698262A (en) * 1984-04-27 1987-10-06 Becton, Dickinson And Company Fluorescently labeled microbeads
US4699828A (en) * 1984-04-27 1987-10-13 Becton, Dickinson And Company Fluorescently labeled microbeads
US4699826A (en) * 1984-04-27 1987-10-13 Becton, Dickinson And Company Fluorescently labeled microbeads
US4609689A (en) * 1984-04-27 1986-09-02 Becton, Dickinson And Company Method of preparing fluorescently labeled microbeads
US4665020A (en) * 1984-05-30 1987-05-12 United States Department Of Energy Flow cytometer measurement of binding assays
US5093234A (en) * 1984-12-24 1992-03-03 Caribbean Microparticles Corporation Method of aligning, compensating, and calibrating a flow cytometer for analysis of samples, and microbead standards kit therefor
US4774189A (en) * 1984-12-24 1988-09-27 Flow Cytometry Standards Corp. Fluorescent calibration microbeads simulating stained cells
US4767206A (en) * 1984-12-24 1988-08-30 Flow Cytometry Standards Corporation Calibration method for flow cytometry using fluorescent microbeads and synthesis thereof
US4918004A (en) * 1984-12-24 1990-04-17 Caribbean Microparticles Corporation Method of calibrating a flow cytometer or fluorescence microscope for quantitating binding antibodies on a selected sample, and microbead calibration kit therefor
US4857451A (en) * 1984-12-24 1989-08-15 Flow Cytometry Standards Corporation Method of compensating and calibrating a flow cytometer, and microbead standards kit therefor
US4828984A (en) * 1986-04-11 1989-05-09 Flow Cytometry Standards Corporation Composition, synthesis and use of simulated cells
NO860171L (no) * 1985-01-30 1986-07-31 Japan Synthetic Rubber Co Ltd Fremgangsmaate for fremstilling av store polymerpartikler.
US4714682A (en) * 1985-12-11 1987-12-22 Flow Cytometry Standards Corporation Fluorescent calibration microbeads simulating stained cells
US4868126A (en) * 1985-12-11 1989-09-19 Flow Cytometry Standards Corporation Method of calibrating a fluorescent microscope using fluorescent calibration microbeads simulating stained cells

Also Published As

Publication number Publication date
EP0511314B1 (de) 1996-12-27
WO1991010893A1 (en) 1991-07-25
DE69123835D1 (de) 1997-02-06
EP0511314A1 (de) 1992-11-04
DE69123835T2 (de) 1997-04-10
US5073497A (en) 1991-12-17
EP0511314A4 (en) 1993-08-04

Similar Documents

Publication Publication Date Title
ATE146879T1 (de) Methode zum einstellen eines strömungzytometers unter verwendung von mikroperlen zum erhalten von reproduzierbaren ergebnissen.
DK296889D0 (da) Fremgangsmaade til analyse af cellekomponenter i en vaeske
DK0461166T3 (da) Fremgangsmåde til styring og/eller overvågning af biologiske processer
DE3750421D1 (de) Lebensfähige Zelle-Markierung.
DE68917879D1 (de) Verfahren und Vorrichtung zur Analyse von Polynucleotid-Sequenzen.
DE69221306D1 (de) Methode zur photometrischen (in vitro) bestimmung des gehaltes eines analyts in einer probe
DK0659055T3 (da) Fremgangsmåde og apparat til analyse af glukose i en biologisk matrix
ATE37238T1 (de) Eine methode zur durchfuehrung eines festphasenimmunoassays unter einbeziehung einer luminiszierenden markierung.
DK0477220T3 (da) Fremgangsmåde til mærkning og sporing af materialer med nukleinsyrer
DE68910730D1 (de) Verfahren zur Unterscheidung zwischen intakten und beschädigten Zellen in einer Probe.
BR9707214A (pt) Processo para analisar uma amostra de constituição desconhecida por meio de um aparelho analìtico.
DK237584D0 (da) Testmateriale til bestemmelse af naervaerelsen af en ion i en testproeve samt dettes anvendelse
ES2118062T3 (es) Composiciones reactivas, metodos y reactivos para la valoracion cuantitativa de magnesio o de calcio y magnesio.
ATE249630T1 (de) Reagent-system und verfahren für differentiation und identifikation von retikulocyten
DE3587510D1 (de) Geraet zur messung von endotoxin.
Lörincz et al. Identification of proteins whose synthesis is modulated during the cell cycle of Saccharomyces cerevisiae
ATE219148T1 (de) Methode zum nachweis von bioindividuen mittels einer nukleinsäureprobe nicht-natürlichen typs und probe zur verwendung hierin
DK0603107T3 (da) Fremgangsmåde til samtidig kvantificering af de vigtigste typer af humane lymfocytter og deres deltyper
EP0301699A3 (de) Verfahren und Gerät zur Bestimmung der Bioaktivität biologischer Proben
Hirsch et al. Comparison of abundant cytosol proteins in rat liver, Novikoff hepatoma, and Morris hepatoma by two-dimensional gel electrophoresis
DK0434319T3 (da) Fremgangsmåde til afprøvning af virkningen af et stof på hårvækst
DE69928250D1 (de) Analytisches verfahren unter verwendung von multipelviren-markierung
ATE142332T1 (de) Verfahren zum sichten von zellen oder geformten körpern mit ausgewählten eigenschaften unter benutzung eines nachweisparameters
DE68915437D1 (de) Verfahren zur bestimmung des typs und des schweregrades von krankheitszuständen des zahnfleisches.
Homma et al. Phase of the circadian clock is accurately transferred from mother to daughter cells in the dinoflagellate Gonyaulax polyedra