ATE147260T1 - Verfahren zur herstellung ölgefüllter paucilamellarer lipidvesikeln - Google Patents

Verfahren zur herstellung ölgefüllter paucilamellarer lipidvesikeln

Info

Publication number
ATE147260T1
ATE147260T1 AT91920355T AT91920355T ATE147260T1 AT E147260 T1 ATE147260 T1 AT E147260T1 AT 91920355 T AT91920355 T AT 91920355T AT 91920355 T AT91920355 T AT 91920355T AT E147260 T1 ATE147260 T1 AT E147260T1
Authority
AT
Austria
Prior art keywords
lipid vesicles
paucilamellar lipid
producing oil
loading
cold
Prior art date
Application number
AT91920355T
Other languages
English (en)
Inventor
Donald F H Wallach
Rajiv Mathur
Original Assignee
Micro Vesicular Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micro Vesicular Systems filed Critical Micro Vesicular Systems
Application granted granted Critical
Publication of ATE147260T1 publication Critical patent/ATE147260T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0008—Detergent materials or soaps characterised by their shape or physical properties aqueous liquid non soap compositions
    • C11D17/0017—Multi-phase liquid compositions
    • C11D17/0021—Aqueous microemulsions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0008—Detergent materials or soaps characterised by their shape or physical properties aqueous liquid non soap compositions
    • C11D17/0026—Structured liquid compositions, e.g. liquid crystalline phases or network containing non-Newtonian phase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Fats And Perfumes (AREA)
  • Medicinal Preparation (AREA)
AT91920355T 1990-10-16 1991-10-15 Verfahren zur herstellung ölgefüllter paucilamellarer lipidvesikeln ATE147260T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/598,120 US5160669A (en) 1988-03-03 1990-10-16 Method of making oil filled paucilamellar lipid vesicles

Publications (1)

Publication Number Publication Date
ATE147260T1 true ATE147260T1 (de) 1997-01-15

Family

ID=24394319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91920355T ATE147260T1 (de) 1990-10-16 1991-10-15 Verfahren zur herstellung ölgefüllter paucilamellarer lipidvesikeln

Country Status (8)

Country Link
US (1) US5160669A (de)
EP (1) EP0558571B1 (de)
JP (1) JP3359031B2 (de)
AT (1) ATE147260T1 (de)
AU (1) AU8947691A (de)
CA (1) CA2093526C (de)
DE (1) DE69124108T2 (de)
WO (1) WO1992006676A1 (de)

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US5405615A (en) * 1991-09-17 1995-04-11 Micro Vesicular Systems, Inc. Sucrose distearate lipid vesicles
DE4221255C2 (de) * 1992-06-26 1994-09-15 Lancaster Group Ag Phospholipide enthaltendes Kosmetikum
DE4221268C2 (de) * 1992-06-26 1997-06-12 Lancaster Group Ag Verwendung eines Dermatikums zur Unterstützung des Sauerstofftransportes in der Haut
US5290542A (en) * 1993-04-08 1994-03-01 The Procter & Gamble Company Oral compositions for treating plaque and gingivitis
US5474761A (en) * 1993-04-08 1995-12-12 The Procter & Gamble Company Oral compositions for treating plaque and gingivitis
US5283056A (en) * 1993-07-01 1994-02-01 International Flavors & Fragrances Inc. Transparent oil-in-water microemulsion flavor or fragrance concentrate, process for preparing same, mouthwash or perfume composition containing said transparent microemulsion concentrate, and process for preparing same
US5853755A (en) * 1993-07-28 1998-12-29 Pharmaderm Laboratories Ltd. Biphasic multilamellar lipid vesicles
DE69425750T2 (de) * 1993-07-28 2001-04-26 Pharmaderm Laboratories Ltd., Saskatoon Zweiphasige multilamellare lipidvesikel
WO1995016437A1 (en) * 1993-12-17 1995-06-22 Micro-Pak, Inc. Method of transmitting a biologically active material to a cell
AU3969595A (en) * 1994-11-03 1996-05-31 Micro-Pak, Inc. Epoxy ester vesicles and paints
US5846551A (en) * 1996-06-10 1998-12-08 E-L Management Corp. Water-based makeup compositions and methods for their preparation
US5776536A (en) * 1996-12-23 1998-07-07 Igen, Inc. Reduced fat chocolate and method of manufacture
US5827533A (en) * 1997-02-06 1998-10-27 Duke University Liposomes containing active agents aggregated with lipid surfactants
US6039960A (en) 1997-05-28 2000-03-21 E-L Management Corp. Water containing wax-based product
DE19813773A1 (de) * 1998-03-27 1999-09-30 Clemens Unger Verfahren zur Herstellung von liposomalen Wirkstoffformulierungen
TW476788B (en) 1998-04-08 2002-02-21 Kimberly Clark Co A cleanser and the making process thereof
US6251425B1 (en) 1998-10-02 2001-06-26 Igen, Inc. Glucoside paucilamellar vesicles
US6080211A (en) * 1999-02-19 2000-06-27 Igen, Inc. Lipid vesicle-based fuel additives and liquid energy sources containing same
US6309664B1 (en) 1999-09-15 2001-10-30 Igen, Incorporated Methods, uses and compositions of fluid petrolatum
EP1304103B1 (de) * 2001-10-22 2008-12-31 Viroblock SA Non-phospholipid Vesikel (npLV) und ihre Verwendung in kosmetischen, therapeutischen und prophylaktischen Anwendungen
FR2840532B1 (fr) * 2002-06-11 2005-05-06 Ethypharm Sa Nanocapsules lipidiques furtives, procede de preparation et utilisation comme vecteur de principes(s) actif(s)
US20040087564A1 (en) * 2002-10-31 2004-05-06 Wright D. Craig Delivery composition and method
KR100854832B1 (ko) 2004-04-05 2008-08-27 각고우호우진 가나가와 다이가쿠 유화 분산제 및 이를 이용한 유화 분산 방법, 유화물, 및에멀젼 연료
US20050232973A1 (en) * 2004-04-19 2005-10-20 Makarand Gore Systems and methods for preparation of pharmaceutical dosage using compositions containing aqueous vesicles
WO2006071659A1 (en) * 2004-12-29 2006-07-06 Trustees Of Boston University Delivery of h2 antagonists
US10251839B2 (en) * 2008-01-22 2019-04-09 Igi Laboratories, Inc. Lipid vesicles derived from olive oil fatty acids
DE102009026718A1 (de) 2009-06-04 2010-04-15 Henkel Ag & Co. Kgaa Hautbehandlung zur Porenverfeinerung II
CA2803282C (en) 2009-07-06 2018-05-01 David E. Anderson Methods for preparing vesicles and formulations produced therefrom
JP5854559B2 (ja) 2009-07-06 2016-02-09 ヴァリエーション バイオテクノロジーズ インコーポレイテッド 小胞を調製する方法及びこれから製造される製剤
EP2576813A1 (de) * 2010-05-28 2013-04-10 Diagon Kft. Verfahren für die zweiphasige zubereitung von liposomen und anwendung dafür bei der herstellung von diagnostischen reagenzien
WO2012006367A2 (en) 2010-07-06 2012-01-12 Variation Biotechnologies, Inc. Compositions and methods for treating influenza
BR112013018074A2 (pt) * 2011-01-13 2020-12-01 Variation Biotechnologies, Inc. métodos para a preparação de vesículas e formulações produzidas a partir dessas
US10736844B2 (en) 2011-01-13 2020-08-11 Variation Biotechnologies Inc. Compositions and methods for treating viral infections
AU2013208693B2 (en) 2012-01-12 2017-12-07 Variation Biotechnologies Inc. Compositions and methods for treating viral infections
EP2806894A4 (de) 2012-01-27 2015-11-04 Variation Biotechnologies Inc Verfahren und zusammensetzungen für therapeutika

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CA795288A (en) * 1966-11-12 1968-09-24 Chapuis Jacques Encapsulated synthetic liquid detergent and process for preparing the same
US3957971A (en) * 1974-07-29 1976-05-18 Lever Brothers Company Moisturizing units and moisturizing compositions containing the same
FR2315991A1 (fr) * 1975-06-30 1977-01-28 Oreal Procede de fabrication de dispersions aqueuses de spherules lipidiques et nouvelles compositions correspondantes
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FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
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Also Published As

Publication number Publication date
DE69124108T2 (de) 1997-04-17
EP0558571A4 (en) 1993-10-27
JP3359031B2 (ja) 2002-12-24
CA2093526C (en) 2002-12-24
CA2093526A1 (en) 1992-04-17
WO1992006676A1 (en) 1992-04-30
DE69124108D1 (de) 1997-02-20
AU8947691A (en) 1992-05-20
US5160669A (en) 1992-11-03
EP0558571B1 (de) 1997-01-08
JPH06504715A (ja) 1994-06-02
EP0558571A1 (de) 1993-09-08

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