ATE147791T1 - Festphasendiagnose von medizinischen konditionen - Google Patents

Festphasendiagnose von medizinischen konditionen

Info

Publication number
ATE147791T1
ATE147791T1 AT90904803T AT90904803T ATE147791T1 AT E147791 T1 ATE147791 T1 AT E147791T1 AT 90904803 T AT90904803 T AT 90904803T AT 90904803 T AT90904803 T AT 90904803T AT E147791 T1 ATE147791 T1 AT E147791T1
Authority
AT
Austria
Prior art keywords
dna
label
solid support
primer pair
pair
Prior art date
Application number
AT90904803T
Other languages
English (en)
Inventor
Mathias Uhlen
Original Assignee
Cemu Bioteknik Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898906642A external-priority patent/GB8906642D0/en
Priority claimed from GB898906641A external-priority patent/GB8906641D0/en
Application filed by Cemu Bioteknik Ab filed Critical Cemu Bioteknik Ab
Application granted granted Critical
Publication of ATE147791T1 publication Critical patent/ATE147791T1/de

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C33/00—Parts of bearings; Special methods for making bearings or parts thereof
    • F16C33/02—Parts of sliding-contact bearings
    • F16C33/04—Brasses; Bushes; Linings
    • F16C33/20—Sliding surface consisting mainly of plastics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6846—Common amplification features

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Mechanical Engineering (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Laminated Bodies (AREA)
  • Sliding-Contact Bearings (AREA)
AT90904803T 1989-03-22 1990-03-15 Festphasendiagnose von medizinischen konditionen ATE147791T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898906642A GB8906642D0 (en) 1989-03-22 1989-03-22 Amplification of target dna
GB898906641A GB8906641D0 (en) 1989-03-22 1989-03-22 Solid phase diagnosis of medical conditions

Publications (1)

Publication Number Publication Date
ATE147791T1 true ATE147791T1 (de) 1997-02-15

Family

ID=26295125

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90904803T ATE147791T1 (de) 1989-03-22 1990-03-15 Festphasendiagnose von medizinischen konditionen

Country Status (8)

Country Link
EP (1) EP0464067B1 (de)
JP (1) JP3152656B2 (de)
KR (1) KR920700360A (de)
AT (1) ATE147791T1 (de)
AU (1) AU646220B2 (de)
CA (1) CA2050681A1 (de)
DE (1) DE69029726T2 (de)
WO (1) WO1990011369A1 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753433A (en) * 1909-12-05 1998-05-19 Boehringer Mannheim Gmbh Method for the sensitive detection of nucleic acids
AU629845B2 (en) * 1988-08-30 1992-10-15 Abbott Laboratories Detection and amplification of target nucleic acid sequences
US5858652A (en) * 1988-08-30 1999-01-12 Abbott Laboratories Detection and amplification of target nucleic acid sequences
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
US5712125A (en) * 1990-07-24 1998-01-27 Cemv Bioteknik Ab Competitive PCR for quantitation of DNA
NZ240079A (en) * 1990-10-09 1993-07-27 Boehringer Mannheim Gmbh Method for the detection of a nucleic acid or part thereof
GB9107124D0 (en) * 1991-04-05 1991-05-22 Dynal As Chemical process
WO1993004199A2 (en) * 1991-08-20 1993-03-04 Scientific Generics Limited Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids
ATE175722T1 (de) * 1991-08-27 1999-01-15 Zeneca Ltd Verfahren zur charakterisierung genomischer dna
US5853989A (en) * 1991-08-27 1998-12-29 Zeneca Limited Method of characterisation of genomic DNA
AU667846B2 (en) * 1991-11-01 1996-04-18 Diatech Pty Ltd Solid phase amplification process
WO1993009250A1 (en) * 1991-11-01 1993-05-13 Adelaide Children's Hospital Solid phase amplification process
IT1252295B (it) * 1991-11-15 1995-06-08 Schiapparelli Diagnostici Ismu Metodo per rivelare acidi nucleici e relativo kit diagnostico
GB9127415D0 (en) * 1991-12-24 1992-02-19 Swordfish Int Ltd Solid support bound detection and diagnostic system
GB9210176D0 (en) * 1992-05-12 1992-06-24 Cemu Bioteknik Ab Chemical method
DE4301693A1 (de) * 1993-01-22 1994-07-28 Cytech Biomedical Inc Verfahren zur Amplifikation und Verfahren zum Nachweis von Polynucleotidsequenzen an fester Phase
JPH08507926A (ja) * 1993-03-19 1996-08-27 シーケノム・インコーポレーテツド エキソヌクレアーゼ分解を介した質量分析法によるｄｎａ配列決定
WO1995021271A1 (en) * 1994-02-07 1995-08-10 Molecular Tool, Inc. Ligase/polymerase-mediated genetic bit analysistm of single nucleotide polymorphisms and its use in genetic analysis
GB9408607D0 (en) * 1994-04-29 1994-06-22 Dynal As Assay
US6090592A (en) * 1994-08-03 2000-07-18 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid on supports
US5641658A (en) * 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
GB9422814D0 (en) * 1994-11-11 1995-01-04 Medinnova Sf Chemical method
DE19526431A1 (de) * 1995-07-21 1997-01-23 Boehringer Mannheim Gmbh Verfahren und Reagenz zur spezifischen Bestimmung von mRNA
GB2308188A (en) * 1995-12-14 1997-06-18 Tepnel Medical Ltd Assaying immobilised nucleic acid by primer extension
US5962271A (en) * 1996-01-03 1999-10-05 Cloutech Laboratories, Inc. Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
GB9604267D0 (en) * 1996-02-29 1996-05-01 Royal Infirmary Of Edinburgh N Mutation assay
IT1284635B1 (it) * 1996-04-24 1998-05-21 Clonit Spa Metodo per la rivelazione di acidi nucleici amplificati e kit per il suo uso.
DE19616750A1 (de) * 1996-04-26 1997-11-06 Newlab Diagnostic Systems Gmbh Verfahren zum Nachweis von Mikroorganismen in Gemischen
GB9624165D0 (en) * 1996-11-19 1997-01-08 Amdex A S Use of nucleic acids bound to carrier macromolecules
US6475724B1 (en) 1997-01-28 2002-11-05 The Regents Of The University Of California Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6171788B1 (en) 1997-01-28 2001-01-09 The Regents Of The University Of California Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US7138511B1 (en) 1997-01-28 2006-11-21 The Regents Of The University Of California Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
EP2327797B1 (de) 1997-04-01 2015-11-25 Illumina Cambridge Limited Verfahren zur Vervielfältigung von Nukleinsäuren
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US5945284A (en) * 1997-05-27 1999-08-31 The Perkin-Elmer Corporation Length determination of nucleic acid repeat sequences by discontinuous primer extension
US5919626A (en) * 1997-06-06 1999-07-06 Orchid Bio Computer, Inc. Attachment of unmodified nucleic acids to silanized solid phase surfaces
US5916776A (en) * 1997-08-27 1999-06-29 Sarnoff Corporation Amplification method for a polynucleotide
WO2001029248A2 (en) * 1999-10-19 2001-04-26 Bionex, Inc. Method for amplifying and detecting nucleic acid
US6642000B1 (en) * 1999-11-12 2003-11-04 University Of Chicago PCR amplification on microarrays of gel immobilized oligonucleotides
JP2001147230A (ja) 1999-11-19 2001-05-29 Hitachi Software Eng Co Ltd バイオチップ読取装置及び標識試薬
US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
ATE316581T1 (de) 2000-09-05 2006-02-15 Zeltz Patrick Dr Verfahren zur spezifischen bestimmung von dna- sequenzen mittels paralleler amplifikation
US7211414B2 (en) 2000-12-01 2007-05-01 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
AR031640A1 (es) 2000-12-08 2003-09-24 Applied Research Systems Amplificacion isotermica de acidos nucleicos en un soporte solido
EP1950305A1 (de) 2001-05-09 2008-07-30 Monsanto Technology, LLC Tyr-A-Gene und ihre Verwendung
JP2003189869A (ja) * 2001-12-27 2003-07-08 Nisshinbo Ind Inc 被検体中に含まれる生物種を判定する方法およびそれに用いるキット
CA2506654C (en) * 2002-11-07 2014-02-25 Yoichi Matsubara Method of detecting gene mutation
US7329490B2 (en) 2003-09-15 2008-02-12 Bristol-Myers Squibb Company Methods for diagnosing schizophrenia by detecting a polymorphism in the KalphaM1 gene
DE102005029810B4 (de) * 2005-06-27 2008-11-13 Siemens Ag Verfahren zum Nachweis von Nukleotidsequenzen, Verwendung des Verfahrens und Testbesteck
US8822670B2 (en) 2005-08-19 2014-09-02 Sumitomo Bakelite Company, Ltd. Method of synthesizing cDNA and method of synthesizing RNA chains, and nucleotide-immobilized carrier
EP2121983A2 (de) 2007-02-02 2009-11-25 Illumina Cambridge Limited Verfahren zur kennzeichnung von proben und sequenzierung mehrerer nukleotidmatrizen
US8455190B2 (en) 2007-08-01 2013-06-04 Dana-Farber Cancer Institute, Inc. Enrichment of a target sequence
EP2617831A3 (de) 2007-11-20 2013-08-07 E. I. du Pont de Nemours and Company Pflanzen mit veränderter Wurzelarchitektur, entsprechende Konstrukte und Verfahren mit für Genen zur Codierung von von Leucinreicher-Repeat-Polypetide und Homologa davon
US8728764B2 (en) 2008-10-02 2014-05-20 Illumina Cambridge Limited Nucleic acid sample enrichment for sequencing applications
US8182994B2 (en) 2009-09-15 2012-05-22 Illumina Cambridge Limited Centroid markers for image analysis of high denisty clusters in complex polynucleotide sequencing
EP2531603A2 (de) 2010-02-02 2012-12-12 E.I. Du Pont De Nemours And Company Pflanzen mit veränderter wurzelarchitektur, entsprechende konstrukte und verfahren mit für lectinproteinkinase (lpk)-polypeptide kodierenden genen und homologen davon
KR101550489B1 (ko) 2010-03-08 2015-09-07 다나-파버 캔서 인스티튜트 인크. 기준 차단 서열을 이용한 완전 ｃｏｌｄ－ｐｃｒ 풍부화
EP3333269B1 (de) 2011-03-31 2021-05-05 Dana-Farber Cancer Institute, Inc. Verfahren zur ermöglichung einer multiplex-kalt-pcr
US9133490B2 (en) 2012-05-16 2015-09-15 Transgenomic, Inc. Step-up method for COLD-PCR enrichment
US10913977B2 (en) 2013-07-24 2021-02-09 Dana-Farber Cancer Institute, Inc. Methods and compositions to enable enrichment of minor DNA alleles by limiting denaturation time in PCR or simply enable enrichment of minor DNA alleles by limiting the denaturation time in PCR
US10370673B2 (en) 2014-09-26 2019-08-06 Purecircle Sdn Bhd Single nucleotide polymorphism (SNP) markers for stevia
DE102015003951A1 (de) 2015-03-26 2016-09-29 Tokushin Denki Co., Ltd. Rohrschwingungs-Kontrollsystem
JP2018133998A (ja) * 2015-07-03 2018-08-30 株式会社カネカ 標的核酸の検出法
WO2018111835A1 (en) 2016-12-12 2018-06-21 Dana-Farber Cancer Institute, Inc. Compositions and methods for molecular barcoding of dna molecules prior to mutation enrichment and/or mutation detection
US20180265887A1 (en) 2017-03-16 2018-09-20 Jacobs Farm Del Cabo Basil Plants With High Tolerance to Downy Mildew
US11174511B2 (en) 2017-07-24 2021-11-16 Dana-Farber Cancer Institute, Inc. Methods and compositions for selecting and amplifying DNA targets in a single reaction mixture

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US200876A (en) * 1878-03-05 Improvement in canister-shot
CA1272443A (en) * 1985-02-22 1990-08-07 Nanibhushan Dattagupta Solution-phase dual hybridization assay for detecting polynucleotide sequences
GB8507706D0 (en) * 1985-03-25 1985-05-01 Genetics Int Inc Magnetic nucleic acid sequences

Also Published As

Publication number Publication date
EP0464067B1 (de) 1997-01-15
JPH04505999A (ja) 1992-10-22
DE69029726T2 (de) 1997-09-04
DE69029726D1 (de) 1997-02-27
WO1990011369A1 (en) 1990-10-04
CA2050681A1 (en) 1990-09-23
JP3152656B2 (ja) 2001-04-03
AU646220B2 (en) 1994-02-17
EP0464067A1 (de) 1992-01-08
AU5272890A (en) 1990-10-22
KR920700360A (ko) 1992-02-19

Similar Documents

Publication Publication Date Title
DE69029726D1 (de) Festphasendiagnose von medizinischen konditionen
AU685144B2 (en) Chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
KR900003379A (ko) 표적 핵산 서열의 증폭 및 검정법
DE69130501D1 (de) Polynukleotid-einfang-assay unter verwendung von in-vitro-amplifikation
EP0360940A3 (de) Polynukleotid-Bestimmung mit selektierbaren Spaltstellen
DE69622347D1 (de) Oligonukleotid-Primer für Amplifizierung von HCV-Nukleinsäure
AU9743398A (en) Detection and identification of human papillomavirus by pcr and type-specific r everse hybridization
GB9016163D0 (en) Chemical method
PL278176A1 (en) Method of detecting sequences of nucleotides and sets for carrying out diagnostic tests
ATE226983T1 (de) Gekoppeltes ampflikation- und ligationverfahren
AU650055B2 (en) Nucleotide sequences useful as type-specific probes, PCR primers and LCR probes for the amplification and detection of human papilloma virus, and related kits and methods
EP2149614A8 (de) Primer zum Nachweis von Mycobacterium tuberculosis
CA2268753A1 (en) Nucleic acid primers and probes for detecting oncogenic human papillomaviruses
EP0707075A3 (de) Spezies-spezifischer Nachweis von Mycobacterium Kansasii
WO1997046709A3 (en) NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING $i(CHLAMYDIA PNEUMONIAE)
ATE347618T1 (de) Verfahren zur amplifikation von nukleinsäuren, das mittel zur strangtrennung und universelle sequenzmarker bereitstellt
CA2213731A1 (en) Methods and reagents for typing hla class i genes
WO2005059505A3 (es) Método y kit para genotipificación de hla-b27 basados en la pcr en tiempo real
WO1998000565A3 (en) NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING $i(MYCOPLASMA PNEUMONIAE)
EP1705255A3 (de) Diagnostisches Verfahren und Kit zur Bestimmung des Kell-Blutgruppengenotyps
CA2093647A1 (en) Method for the sensitive detection of nucleic acids
WO1999024607A3 (en) DETECTION AND TYPING OF THE iceA GENE OF $i(HELICOBACTER PYLORI)