ATE147978T1 - Verwendung von (e) - 2 - (p -fluorophenethyl)- 3 - fluoroallylamine zur behandlung der alzheimerschen krankheit - Google Patents

Verwendung von (e) - 2 - (p -fluorophenethyl)- 3 - fluoroallylamine zur behandlung der alzheimerschen krankheit

Info

Publication number
ATE147978T1
ATE147978T1 AT93909326T AT93909326T ATE147978T1 AT E147978 T1 ATE147978 T1 AT E147978T1 AT 93909326 T AT93909326 T AT 93909326T AT 93909326 T AT93909326 T AT 93909326T AT E147978 T1 ATE147978 T1 AT E147978T1
Authority
AT
Austria
Prior art keywords
fluoroallylamine
fluorophenethyl
alzheimer
disease
treatment
Prior art date
Application number
AT93909326T
Other languages
English (en)
Inventor
Ian A Mcdonald
Michael G Palfreyman
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE147978T1 publication Critical patent/ATE147978T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93909326T 1992-05-27 1993-04-14 Verwendung von (e) - 2 - (p -fluorophenethyl)- 3 - fluoroallylamine zur behandlung der alzheimerschen krankheit ATE147978T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88867192A 1992-05-27 1992-05-27

Publications (1)

Publication Number Publication Date
ATE147978T1 true ATE147978T1 (de) 1997-02-15

Family

ID=25393634

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93909326T ATE147978T1 (de) 1992-05-27 1993-04-14 Verwendung von (e) - 2 - (p -fluorophenethyl)- 3 - fluoroallylamine zur behandlung der alzheimerschen krankheit

Country Status (15)

Country Link
EP (1) EP0642338B1 (de)
JP (1) JPH07507299A (de)
KR (1) KR950701518A (de)
AT (1) ATE147978T1 (de)
AU (1) AU672401B2 (de)
CA (1) CA2135752C (de)
DE (1) DE69307702T2 (de)
DK (1) DK0642338T3 (de)
ES (1) ES2101311T3 (de)
GR (1) GR3022608T3 (de)
HU (1) HUT72316A (de)
MX (1) MX9303074A (de)
NO (1) NO944524D0 (de)
WO (1) WO1993024120A1 (de)
ZA (1) ZA933567B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0720475A1 (de) * 1993-09-24 1996-07-10 Merrell Pharmaceuticals Inc. Transdermales system enthaltend (e)-2-(p-fluorophenethyl)-3-fluoroallylamin zur behandlung der alzheimerschen krankheit
US5488188A (en) * 1994-09-29 1996-01-30 Merrell Dow Pharmaceuticals Inc. Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof
US5599986A (en) * 1994-09-29 1997-02-04 Hoechst Marion Roussel Inc. Process for the preparation of alkali metal salts of diformylamide
US20070293548A1 (en) * 2006-03-31 2007-12-20 Wang Eric Y Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment and prevention of diseases
EP1870097A1 (de) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidederivate zur Behandlung von kognitiven Störungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR243493A1 (es) * 1987-06-16 1993-08-31 Merrell Dow Pharma Procedimiento para preparar (e)-2-(p-fluorfenetil)-3-fluoralilamina y sus sales farmaceuticamente aceptables, util como inhibidor de mao-b irreversible y activado por enzimas.

Also Published As

Publication number Publication date
NO944524L (no) 1994-11-25
JPH07507299A (ja) 1995-08-10
ES2101311T3 (es) 1997-07-01
EP0642338A1 (de) 1995-03-15
MX9303074A (es) 1994-01-31
WO1993024120A1 (en) 1993-12-09
HUT72316A (en) 1996-04-29
DK0642338T3 (da) 1997-02-10
NO944524D0 (no) 1994-11-25
EP0642338B1 (de) 1997-01-22
DE69307702D1 (de) 1997-03-06
CA2135752C (en) 1998-07-14
AU672401B2 (en) 1996-10-03
GR3022608T3 (en) 1997-05-31
ZA933567B (en) 1993-12-13
HU9403384D0 (en) 1995-02-28
AU3978293A (en) 1993-12-30
CA2135752A1 (en) 1993-12-09
KR950701518A (ko) 1995-04-28
DE69307702T2 (de) 1997-05-28

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