ATE148111T1 - Verfahren zur herstellung von taxanderivaten, die so erlangten neuen derivate und diese enthaltende zusammensetzungen - Google Patents

Verfahren zur herstellung von taxanderivaten, die so erlangten neuen derivate und diese enthaltende zusammensetzungen

Info

Publication number
ATE148111T1
ATE148111T1 AT94900862T AT94900862T ATE148111T1 AT E148111 T1 ATE148111 T1 AT E148111T1 AT 94900862 T AT94900862 T AT 94900862T AT 94900862 T AT94900862 T AT 94900862T AT E148111 T1 ATE148111 T1 AT E148111T1
Authority
AT
Austria
Prior art keywords
derivatives
pct
formula
date
taxand
Prior art date
Application number
AT94900862T
Other languages
English (en)
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of ATE148111T1 publication Critical patent/ATE148111T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT94900862T 1992-11-23 1993-11-22 Verfahren zur herstellung von taxanderivaten, die so erlangten neuen derivate und diese enthaltende zusammensetzungen ATE148111T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214023A FR2698363B1 (fr) 1992-11-23 1992-11-23 Nouveaux dérivés du taxane, leur préparation et les compositions qui les contiennent.

Publications (1)

Publication Number Publication Date
ATE148111T1 true ATE148111T1 (de) 1997-02-15

Family

ID=9435782

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94900862T ATE148111T1 (de) 1992-11-23 1993-11-22 Verfahren zur herstellung von taxanderivaten, die so erlangten neuen derivate und diese enthaltende zusammensetzungen

Country Status (23)

Country Link
US (1) US5606083A (de)
EP (1) EP0669916B1 (de)
JP (1) JPH08503486A (de)
KR (1) KR950704286A (de)
AT (1) ATE148111T1 (de)
AU (1) AU680455B2 (de)
CA (1) CA2149758A1 (de)
CZ (1) CZ131795A3 (de)
DE (1) DE69307730T2 (de)
DK (1) DK0669916T3 (de)
ES (1) ES2096440T3 (de)
FI (1) FI952482L (de)
FR (1) FR2698363B1 (de)
GR (1) GR3022359T3 (de)
HU (1) HUT74069A (de)
NO (1) NO952017D0 (de)
NZ (1) NZ258144A (de)
PL (1) PL309037A1 (de)
RU (1) RU95113421A (de)
SK (1) SK68195A3 (de)
TW (1) TW254938B (de)
WO (1) WO1994012484A1 (de)
ZA (1) ZA938728B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698582A (en) * 1991-07-08 1997-12-16 Rhone-Poulenc Rorer S.A. Compositions containing taxane derivatives
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US5677470A (en) 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
EP0773938B1 (de) * 1994-07-26 1999-02-03 INDENA S.p.A. Semisynthetisch taxal derivate mit antitumor wirkung
CA2170661A1 (en) * 1995-03-22 1996-09-23 John K. Thottathil Novel methods for the preparation of taxanes using oaxzolidine intermediates
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US20030157187A1 (en) * 1996-12-02 2003-08-21 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating or preventing inflammatory diseases
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US7288665B1 (en) 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
ATE234800T1 (de) 1997-08-21 2003-04-15 Univ Florida State Verfahren zur synthese von taxanen
HK1049787B (en) 1999-10-01 2014-07-25 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
WO2004033442A2 (en) * 2002-10-09 2004-04-22 Chatham Biotec Ltd. Novel taxanes and methods related to use and preparation thereof
US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
US20080161324A1 (en) * 2006-09-14 2008-07-03 Johansen Lisa M Compositions and methods for treatment of viral diseases
FR2986526A1 (fr) 2012-02-03 2013-08-09 Sanofi Sa Procede de preparation de derives du taxol et certains composes intermediaires
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FI952482L (fi) 1995-05-24
TW254938B (de) 1995-08-21
FR2698363B1 (fr) 1994-12-30
KR950704286A (ko) 1995-11-17
HUT74069A (en) 1996-10-28
CA2149758A1 (fr) 1994-06-09
ES2096440T3 (es) 1997-03-01
AU680455B2 (en) 1997-07-31
DE69307730T2 (de) 1997-06-05
EP0669916B1 (de) 1997-01-22
US5606083A (en) 1997-02-25
AU5565994A (en) 1994-06-22
CZ131795A3 (en) 1995-10-18
FI952482A0 (fi) 1995-05-22
NO952017L (no) 1995-05-22
JPH08503486A (ja) 1996-04-16
PL309037A1 (en) 1995-09-18
HU9501500D0 (en) 1995-07-28
FR2698363A1 (fr) 1994-05-27
DK0669916T3 (da) 1997-02-10
GR3022359T3 (en) 1997-04-30
RU95113421A (ru) 1997-03-20
FI952482A7 (fi) 1995-05-22
NO952017D0 (no) 1995-05-22
EP0669916A1 (de) 1995-09-06
WO1994012484A1 (fr) 1994-06-09
DE69307730D1 (de) 1997-03-06
NZ258144A (en) 1996-10-28
ZA938728B (en) 1994-06-28
SK68195A3 (en) 1995-10-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee