ATE148633T1 - Verfahren und vorrichtung zur freisetzung von arzneimittel an die haut - Google Patents

Verfahren und vorrichtung zur freisetzung von arzneimittel an die haut

Info

Publication number
ATE148633T1
ATE148633T1 AT90906485T AT90906485T ATE148633T1 AT E148633 T1 ATE148633 T1 AT E148633T1 AT 90906485 T AT90906485 T AT 90906485T AT 90906485 T AT90906485 T AT 90906485T AT E148633 T1 ATE148633 T1 AT E148633T1
Authority
AT
Austria
Prior art keywords
clay
adhesiveness
drug
adhesive
skin
Prior art date
Application number
AT90906485T
Other languages
English (en)
Inventor
Steven Sablotsky
Joseph A Gentile
Original Assignee
Noven Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noven Pharma filed Critical Noven Pharma
Application granted granted Critical
Publication of ATE148633T1 publication Critical patent/ATE148633T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A61L15/585—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • A61L2300/222—Steroids, e.g. corticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Surgery (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
AT90906485T 1990-03-28 1990-03-28 Verfahren und vorrichtung zur freisetzung von arzneimittel an die haut ATE148633T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1990/001750 WO1991014463A1 (en) 1990-03-28 1990-03-28 Method and device for the release of drugs to the skin

Publications (1)

Publication Number Publication Date
ATE148633T1 true ATE148633T1 (de) 1997-02-15

Family

ID=22220767

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90906485T ATE148633T1 (de) 1990-03-28 1990-03-28 Verfahren und vorrichtung zur freisetzung von arzneimittel an die haut

Country Status (9)

Country Link
EP (1) EP0474647B1 (de)
AT (1) ATE148633T1 (de)
BR (1) BR9008012A (de)
DE (1) DE69029909T2 (de)
DK (1) DK0474647T3 (de)
ES (1) ES2097145T3 (de)
FI (1) FI924313L (de)
NO (1) NO923699L (de)
WO (1) WO1991014463A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
EP0708627B1 (de) * 1993-07-09 2000-02-02 Cygnus, Inc. Verfahren und vorrichtung für die transdermale oder transbuccale therapeutische verabreichung von nikotinsubstituten
JP2819236B2 (ja) * 1994-05-06 1998-10-30 日東電工株式会社 経皮吸収製剤
GB9409778D0 (en) 1994-05-16 1994-07-06 Dumex Ltd As Compositions
AU4761196A (en) * 1995-01-19 1996-08-07 Cygnus, Inc. Polymer adhesive formulation containing sorbent particles
US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US6461596B1 (en) * 1997-02-18 2002-10-08 Andrea Taylor Composition and method for promoting hair growth
US5948433A (en) * 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US7030155B2 (en) 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
WO2000040219A1 (en) 1998-12-30 2000-07-13 Dexcel Ltd. Dispersible concentrate for the delivery of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
EP1998756A2 (de) 2006-02-27 2008-12-10 Noven Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur abgabe von aminofunktionellen arzneimitteln
US20120280459A1 (en) * 2011-05-06 2012-11-08 Oatey Co. Stainfree plumber's putty
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
US10046151B2 (en) 2013-07-03 2018-08-14 Lts Lohmann Therapie-Systeme, Ag Transdermal therapeutic system with electronic component
US11633367B2 (en) 2014-05-20 2023-04-25 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system containing rotigotine
WO2015177212A1 (en) 2014-05-20 2015-11-26 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an interface mediator
WO2015177209A1 (en) 2014-05-20 2015-11-26 Lts Lohmann Therapie-Systeme Ag Method for adjusting the release of active agent in a transdermal delivery system
AU2016347548A1 (en) * 2015-10-28 2018-02-22 Technology Innovation Momentum Fund (Israel) Limited Partnership Composite bioadhesive sealant

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1051320A (en) 1964-01-13 1966-12-14 W.R. Grace & Co. Micro-porous polyethylene and a process for the manufacture thereof
US3948262A (en) 1969-04-01 1976-04-06 Alza Corporation Novel drug delivery device
US4144317A (en) 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
JPS56133381A (en) 1980-03-25 1981-10-19 Nippon Kayaku Co Ltd Pressure-sensitive adhesive tape or sheet containing nitroglycerin
US4379454A (en) 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4814168A (en) * 1988-03-04 1989-03-21 Noven Pharmaceuticals, Inc. Transdermal multipolymer drug delivery system
US4994267A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system

Also Published As

Publication number Publication date
DE69029909T2 (de) 1997-09-11
EP0474647B1 (de) 1997-02-05
FI924313A7 (fi) 1992-09-25
WO1991014463A1 (en) 1991-10-03
DE69029909D1 (de) 1997-03-20
BR9008012A (pt) 1992-12-01
NO923699D0 (no) 1992-09-24
ES2097145T3 (es) 1997-04-01
DK0474647T3 (da) 1997-08-18
EP0474647A1 (de) 1992-03-18
FI924313A0 (fi) 1992-09-25
FI924313L (fi) 1992-09-25
NO923699L (no) 1993-02-01

Similar Documents

Publication Publication Date Title
ATE148633T1 (de) Verfahren und vorrichtung zur freisetzung von arzneimittel an die haut
CA2027053A1 (en) Estrogen-Containing Active Substance Plaster
YU166388A (sh) Naprava za nanošenje na kožu nitroglicerina, i postupci za proizvodnju iste i primena iste
DE3879853D1 (de) Klebstoffzusammensetzung, zusammensetzung mit kontrollierter wirkstofffreisetzung und system zur transdermalen anwendung von arzneien.
IE800059L (en) Polymeric diffusion matrix
DE59010095D1 (de) Pflaster als therapeutisches System zur Verabreichung von Wirkstoffen an die Haut mit einer abgestuften Wirkstoffabgabe, Verfahren zu seiner Herstellung sowie Verwendung
PT737066E (pt) Dispositivo transdermico contendo polivinilpirrolidona como potenciador de solubilidade
KR900015761A (ko) 경피성 단일체 시스템
DE69325495D1 (de) Extrudierbare Zusammensetzungen zur topischen oder transdermalen Wirkstoffabgabe
MY109926A (en) Transdermal therapeutic system comprising galanthamine as active component
NL970007I1 (nl) Transdermaal oestradiotoedieningssysteem.
HU896714D0 (en) Process for producing of medical device containing fisostigmine as agent being absorbed by skin
JP2013163820A (ja) 経皮薬物送達システムにおいて有用な非反応型接着剤
ATE238778T1 (de) Transdermales therapeutisches system zur abgabe von hormonen
IL106512A (en) Plaster for the transdermal application of steroid hormones and process for the preparation thereof
ATE12731T1 (de) Polymere diffusionsmatrix und verfahren zu deren herstellung.
DE3485306D1 (de) Pharmazeutische zusammensetzung mit verzoegerter abgabe und verfahren zu deren herstellung.
YU49390A (sh) Postupak za izradu transdermalnog terapijskog sistema sa stupnjevitim otpuštanjem aktivne materije
MY110391A (en) Nitroglycerin-containing patch, a process for the production and the use thereof
DE68902105D1 (de) Vorrichtung zur gleichmaessigen abgabe von arzneimitteln fuer veterinaere anwendung.
ATE185069T1 (de) Flächenstabilisierte pharmazeutische zubereitung zur anwendung auf der haut
MD937C2 (ro) Sistem terapeutic transdermal pentru aplicarea cutanală a fizostigminei pe piele şi procedeu de obţinere a lui
ATE64539T1 (de) Dermale und transdermale therapeutische systeme mit musterfoermig aufgetragener klebschicht, sowie verfahren zur dessen herstellung.
DE602004018530D1 (de) Zusammensetzung, die als klebstoff verwendet werden kann, und verwendung einer derartigen zusammensetzung
JPS5813524B2 (ja) 動物用外用部材

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time