ATE148794T1 - Messvorrichtung und messystem für proben - Google Patents

Messvorrichtung und messystem für proben

Info

Publication number
ATE148794T1
ATE148794T1 AT92120175T AT92120175T ATE148794T1 AT E148794 T1 ATE148794 T1 AT E148794T1 AT 92120175 T AT92120175 T AT 92120175T AT 92120175 T AT92120175 T AT 92120175T AT E148794 T1 ATE148794 T1 AT E148794T1
Authority
AT
Austria
Prior art keywords
flow passage
passage portion
sample
measuring position
measuring
Prior art date
Application number
AT92120175T
Other languages
English (en)
Inventor
Takeshi C O Canon Kab Miyazaki
Matsuomi C O Canon K Nishimura
Takayuki C O Canon Kabush Yagi
Kazumi C O Canon Kabush Tanaka
Toshikazu C O Canon Ka Ohnishi
Masanori C O Canon Sakuranaga
Yoshito C O Canon Kab Yoneyama
Hidehito C O Canon Ka Takayama
Kazuo C O Canon Kabushik Isaka
Original Assignee
Canon Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4264895A external-priority patent/JP2832117B2/ja
Application filed by Canon Kk filed Critical Canon Kk
Application granted granted Critical
Publication of ATE148794T1 publication Critical patent/ATE148794T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442—Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0466—Evaporation to induce underpressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1039—Micropipettes, e.g. microcapillary tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1041—Ink-jet like dispensers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
AT92120175T 1991-11-29 1992-11-26 Messvorrichtung und messystem für proben ATE148794T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31648191 1991-11-29
JP4264895A JP2832117B2 (ja) 1991-11-29 1992-10-02 サンプル測定デバイス及びサンプル測定システム

Publications (1)

Publication Number Publication Date
ATE148794T1 true ATE148794T1 (de) 1997-02-15

Family

ID=26546730

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92120175T ATE148794T1 (de) 1991-11-29 1992-11-26 Messvorrichtung und messystem für proben

Country Status (4)

Country Link
US (1) US5370842A (de)
EP (1) EP0545284B1 (de)
AT (1) ATE148794T1 (de)
DE (1) DE69217331T2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112672641A (zh) * 2018-09-24 2021-04-16 莱利专利股份有限公司 带有检测系统的挤奶系统

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1316666C (en) * 1987-10-22 1993-04-27 Robert E. Duthie, Jr. Sterilization method and apparatus
JPH0610900A (ja) * 1992-04-27 1994-01-21 Canon Inc 液体移動方法及び移動装置ならびにこれを利用した測定装置
JP3083037B2 (ja) * 1993-03-16 2000-09-04 キヤノン株式会社 マスク製造方法及び製造装置、ならびにこれを用いて作製されたマスクと、該マスクを用いたデバイス製造方法
US6203759B1 (en) 1996-05-31 2001-03-20 Packard Instrument Company Microvolume liquid handling system
US6537817B1 (en) 1993-05-31 2003-03-25 Packard Instrument Company Piezoelectric-drop-on-demand technology
US6521187B1 (en) 1996-05-31 2003-02-18 Packard Instrument Company Dispensing liquid drops onto porous brittle substrates
AU1911795A (en) * 1994-02-09 1995-08-29 Abbott Laboratories Diagnostic flow cell device
DE4417079C2 (de) * 1994-05-17 1998-06-10 Fraunhofer Ges Forschung Objektträger zum Beobachten von biologischem Material
US5602039A (en) * 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
US5602349A (en) * 1994-10-14 1997-02-11 The University Of Washington Sample introduction system for a flow cytometer
US6861265B1 (en) * 1994-10-14 2005-03-01 University Of Washington Flow cytometer droplet formation system
DE69532416T2 (de) * 1994-10-14 2004-12-02 University Of Washington, Seattle Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie
DK0725267T3 (da) * 1995-02-01 1999-08-02 Rossendorf Forschzent Elektrisk styrbar mikropipette
DE19512117A1 (de) 1995-04-04 1996-10-10 Itt Ind Gmbh Deutsche Meßeinrichtung
FR2734637B1 (fr) * 1995-05-24 1997-08-14 Abx Sa Dispositif d'inspection optique d'un fluide, notamment pour analyses hematologiques
DE69610218T2 (de) * 1995-11-17 2001-01-25 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno, Den Haag/S'gravenhage Photometrisches messsystem und halter für ein solches system
AT403745B (de) * 1996-02-29 1998-05-25 Avl Verbrennungskraft Messtech Messanordnung mit einem für anregungs- und messstrahlung transparentem trägerelement
US6083762A (en) * 1996-05-31 2000-07-04 Packard Instruments Company Microvolume liquid handling system
DE69727422T2 (de) * 1996-05-31 2004-07-01 Packard Instrument Co., Inc., Downers Grove Vorrichtung zur Handhabung von Mikroflüssigkeitsmengen
US5779868A (en) * 1996-06-28 1998-07-14 Caliper Technologies Corporation Electropipettor and compensation means for electrophoretic bias
JP3361530B2 (ja) 1996-06-28 2003-01-07 カリパー・テクノロジーズ・コープ. 電子ピペッタおよび電気泳動バイアスのための補償手段
US6280967B1 (en) * 1996-08-02 2001-08-28 Axiom Biotechnologies, Inc. Cell flow apparatus and method for real-time of cellular responses
US5804436A (en) 1996-08-02 1998-09-08 Axiom Biotechnologies, Inc. Apparatus and method for real-time measurement of cellular response
US6558916B2 (en) 1996-08-02 2003-05-06 Axiom Biotechnologies, Inc. Cell flow apparatus and method for real-time measurements of patient cellular responses
DE69830598T2 (de) 1997-01-31 2006-05-18 The Horticulture And Food Research Institute Of New Zealand Limited Optische vorrichtung und methode
AU6963798A (en) * 1997-04-08 1998-10-30 Packard Instrument Company Inc. Microvolume liquid handling system
DE19737173B4 (de) * 1997-08-26 2007-04-05 Eppendorf Ag Mikrodosiersystem
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
EP1619491B1 (de) * 1998-05-16 2009-03-11 Applera Corporation Optisches Gerät insbesondere zur Überwachung von DNS-Polymerasekettenreaktionen
US6830729B1 (en) * 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
CA2320296A1 (en) 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
NZ509434A (en) 1998-07-30 2004-03-26 Univ Colorado State Res Found Equine system for non-surgical artificial insemination
DE19933458B4 (de) * 1999-07-15 2015-08-20 Eppendorf Ag Einrichtungen und Systeme zum Handhaben von Flüssigkeitsproben
ES2158808B1 (es) * 1999-10-15 2002-04-01 Consejo Superior Investigacion Sistema electromagnetico para la manipulacion de fluidos.
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US6699713B2 (en) * 2000-01-04 2004-03-02 The Regents Of The University Of California Polymerase chain reaction system
EP1738829A1 (de) * 2000-01-04 2007-01-03 The Regents of the University of California Polymerase-Kettenreaktionssystem
AU2711201A (en) * 2000-01-31 2001-08-14 Matsushita Seiko Kk Kit for detecting microorganisms, apparatus for quanitifying microorganisms and method for quantifying microorganisms
WO2001077640A2 (en) * 2000-04-05 2001-10-18 Alexion Pharmaceuticals, Inc. Methods and devices for storing and dispensing liquids
EP2258170B1 (de) 2000-05-09 2017-07-12 Xy, Llc Hochreines X-Chromosom-Lager und Y-Chromosom-Lagerpopulationen von Spermatozoiden
US6875402B2 (en) * 2000-10-16 2005-04-05 Ngk Insulators, Ltd. Micropipette, dispenser and method for producing biochip
AU2002237689B2 (en) 2000-11-29 2008-01-10 Xy, Llc. System to separate frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
ES2405320T3 (es) 2001-05-17 2013-05-30 Beckman Coulter, Inc. Citómetro de flujo con un sistema de alienación óptica automatizado activo
US6844563B2 (en) * 2001-05-22 2005-01-18 Matsushita Electric Industrial Co., Ltd. Fluorescence detecting device with integrated circuit and photodiode, and detection method
JP2004534226A (ja) * 2001-06-29 2004-11-11 メソ スケイル テクノロジーズ,エルエルシー 発光試験測定用のアッセイプレート、リーダシステム及び方法
US6767733B1 (en) * 2001-10-10 2004-07-27 Pritest, Inc. Portable biosensor apparatus with controlled flow
FI115343B (fi) * 2001-10-22 2005-04-15 Filtronic Lk Oy Sisäinen monikaista-antenni
US20040020993A1 (en) * 2001-12-28 2004-02-05 Green Larry R. Method for luminescent identification and calibration
EP1323474A1 (de) * 2001-12-31 2003-07-02 Corning Incorporated Vorrichtung und Verfahren zum simultanen Transfer von Flüssigkeiten
DE10206464A1 (de) * 2002-02-16 2003-08-28 Micronas Gmbh Verfahren zur Herstellung einer Sensor- oder Aktuatoranordnung sowie Sensor- oder Aktuatoranordnung
JP2004000144A (ja) 2002-03-29 2004-01-08 Aisin Seiki Co Ltd 細胞分離選別装置、細胞整列用基板
US20040060987A1 (en) * 2002-05-07 2004-04-01 Green Larry R. Digital image analysis method for enhanced and optimized signals in fluorophore detection
DE10222228A1 (de) * 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Mikropumpe mit Heizelementen für einen pulsierten Betrieb
US6982166B2 (en) 2002-05-16 2006-01-03 Applera Corporation Lens assembly for biological testing
US9157860B2 (en) 2002-05-16 2015-10-13 Applied Biosystems, Llc Achromatic lens array
US20040129579A1 (en) * 2002-07-23 2004-07-08 Crooks Richard M. Photonic signal reporting of electrochemical events
CA2532376C (en) 2002-08-01 2015-05-12 Colorado State University Research Foundation Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
BRPI0313476B1 (pt) 2002-08-15 2015-06-23 Xy Llc Citômetro de fluxo de alta resolução
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US7294312B2 (en) * 2003-02-20 2007-11-13 Medtronic, Inc. Test cartridge holder for blood samples
US6861251B2 (en) 2003-02-24 2005-03-01 Pritest, Inc. Translucent solid matrix assay device for microarray analysis
DK2308419T3 (da) 2003-03-28 2016-06-06 Inguran Llc Fremgangsmåde til bedømmelse af farvningstilstandene for dyresperm, som skal sorteres.
EP1473084B1 (de) * 2003-03-31 2015-07-29 Canon Kabushiki Kaisha Behälter für biochemische Reaktionen
WO2004101151A1 (en) 2003-05-08 2004-11-25 Nanostream, Inc. Sample preparation for parallel chromatography
NZ544103A (en) 2003-05-15 2010-10-29 Xy Llc Efficient haploid cell sorting for flow cytometer systems
US20040258563A1 (en) 2003-06-23 2004-12-23 Applera Corporation Caps for sample wells and microcards for biological materials
US7276351B2 (en) 2003-09-10 2007-10-02 Seahorse Bioscience Method and device for measuring multiple physiological properties of cells
US8658349B2 (en) 2006-07-13 2014-02-25 Seahorse Bioscience Cell analysis apparatus and method
US7396512B2 (en) 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
US7981362B2 (en) 2003-11-04 2011-07-19 Meso Scale Technologies, Llc Modular assay plates, reader systems and methods for test measurements
JP4632400B2 (ja) * 2003-12-16 2011-02-16 キヤノン株式会社 細胞培養用基板、その製造方法、それを用いた細胞スクリーニング法
WO2005059086A1 (en) * 2003-12-16 2005-06-30 Canon Kabushiki Kaisha Biologically active substance transfer sheet, cell culture kit constituted of cell culture plate and biologically active substance transfer sheet, producing method thereof and method for screening cell culture conditions utilizing the same
JP4464158B2 (ja) * 2004-02-13 2010-05-19 キヤノン株式会社 生化学反応カートリッジ
DE102004008685A1 (de) * 2004-02-21 2005-09-29 Roche Diagnostics Gmbh Transmissionsspektrometer zur Untersuchung einer flüssigen Probe
JP2007531523A (ja) 2004-03-29 2007-11-08 モンサント テクノロジー エルエルシー Xまたはy染色体担持豊富化集団に仕分けるための精子懸濁液
WO2005108960A1 (ja) * 2004-05-06 2005-11-17 Matsushita Electric Industrial Co., Ltd. センサ、測定装置および測定方法
JP4515162B2 (ja) * 2004-06-15 2010-07-28 キヤノン株式会社 Dnaインターカレート物質類の吸着用構造物
CA2574499C (en) 2004-07-22 2016-11-29 Monsanto Technology Llc Process for enriching a population of sperm cells
ES2607527T3 (es) 2004-07-27 2017-03-31 Beckman Coulter, Inc. Mejora de la discriminación en citometría de flujo con transformación geométrica implementada por ordenador
US7291824B2 (en) * 2005-12-22 2007-11-06 Palo Alto Research Center Incorporated Photosensing throughout energy range and in subranges
JP4147235B2 (ja) * 2004-09-27 2008-09-10 キヤノン株式会社 吐出用液体、吐出方法、液滴化方法、液体吐出カートリッジ及び吐出装置
JP4683633B2 (ja) * 2004-11-09 2011-05-18 キヤノン株式会社 液体の分析システムおよびカートリッジ
JP4689340B2 (ja) * 2005-05-02 2011-05-25 キヤノン株式会社 吐出用液体医薬組成物
US7618770B2 (en) 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US20090170210A1 (en) * 2005-10-28 2009-07-02 Atsushi Fukunaga Measuring device, measuring apparatus and method of measuring
CN101233407B (zh) * 2005-10-28 2011-01-12 松下电器产业株式会社 测定仪器、测定装置和测定方法
US7386199B2 (en) * 2005-12-22 2008-06-10 Palo Alto Research Center Incorporated Providing light to channels or portions
US7358476B2 (en) * 2005-12-22 2008-04-15 Palo Alto Research Center Incorporated Sensing photons from objects in channels
US7547904B2 (en) * 2005-12-22 2009-06-16 Palo Alto Research Center Incorporated Sensing photon energies emanating from channels or moving objects
US7420677B2 (en) * 2005-12-22 2008-09-02 Palo Alto Research Center Incorporated Sensing photon energies of optical signals
JP2007286045A (ja) * 2006-03-20 2007-11-01 Canon Inc 検出装置、検出素子用基板、検出素子、検出素子用キット及び検出方法
ATE499984T1 (de) 2007-01-10 2011-03-15 Hoffmann La Roche Vorrichtung zum bestimmen eines analyts in einer flüssigkeit und verfahren
US9164037B2 (en) 2007-01-26 2015-10-20 Palo Alto Research Center Incorporated Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances
US8821799B2 (en) 2007-01-26 2014-09-02 Palo Alto Research Center Incorporated Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity
US7554673B2 (en) * 2007-02-05 2009-06-30 Palo Alto Research Center Incorporated Obtaining information about analytes using optical cavity output light
US7633629B2 (en) 2007-02-05 2009-12-15 Palo Alto Research Center Incorporated Tuning optical cavities
US7817276B2 (en) 2007-02-05 2010-10-19 Palo Alto Research Center Incorporated Distinguishing objects
US7936463B2 (en) 2007-02-05 2011-05-03 Palo Alto Research Center Incorporated Containing analyte in optical cavity structures
US7545513B2 (en) * 2007-02-05 2009-06-09 Palo Alto Research Center Incorporated Encoding optical cavity output light
EP2570811B1 (de) 2007-02-09 2014-11-26 Advanced Liquid Logic, Inc. Tröpfchenaktuatorvorrichtungen und Verfahren mit magnetischen Beads
EP1985994A1 (de) * 2007-04-27 2008-10-29 Radiometer Medical ApS Optisches Sensorsystem
DE102007021544A1 (de) * 2007-05-08 2008-11-13 Siemens Ag Messeinheit und Verfahren zur optischen Untersuchung einer Flüssigkeit auf eine Analytkonzentration
US7522811B2 (en) * 2007-07-13 2009-04-21 Palo Alto Research Center Incorporated Producing sandwich waveguides
US7529438B2 (en) * 2007-07-13 2009-05-05 Palo Alto Research Center Incorporated Producing fluidic waveguides
CN101910821B (zh) * 2007-12-04 2012-09-05 粒子监测系统有限公司 非正交粒子检测系统和方法
US8320983B2 (en) 2007-12-17 2012-11-27 Palo Alto Research Center Incorporated Controlling transfer of objects affecting optical characteristics
US8153949B2 (en) * 2008-12-18 2012-04-10 Palo Alto Research Center Incorporated Obtaining sensing results indicating time variation
US7763856B2 (en) * 2008-01-31 2010-07-27 Palo Alto Research Center Incorporated Producing time variation in emanating light
US8153950B2 (en) * 2008-12-18 2012-04-10 Palo Alto Research Center Incorporated Obtaining sensing results and/or data in response to object detection
US7817254B2 (en) * 2008-01-30 2010-10-19 Palo Alto Research Center Incorporated Obtaining information from time variation of sensing results
US7894068B2 (en) * 2008-02-04 2011-02-22 Palo Alto Research Center Incorporated Producing filters with combined transmission and/or reflection functions
US8263955B2 (en) * 2008-12-18 2012-09-11 Palo Alto Research Center Incorporated Causing relative motion
US7701580B2 (en) * 2008-02-01 2010-04-20 Palo Alto Research Center Incorporated Transmitting/reflecting emanating light with time variation
US8629981B2 (en) 2008-02-01 2014-01-14 Palo Alto Research Center Incorporated Analyzers with time variation based on color-coded spatial modulation
US8373860B2 (en) * 2008-02-01 2013-02-12 Palo Alto Research Center Incorporated Transmitting/reflecting emanating light with time variation
EP2370111B1 (de) 2008-12-25 2014-11-05 Canon Kabushiki Kaisha Sonde für eine biologische probe und markierungsverfahren und screeningverfahren unter verwendung der sonde
JP5487638B2 (ja) 2009-02-17 2014-05-07 ソニー株式会社 微小粒子分取のための装置及びマイクロチップ
WO2011008233A1 (en) * 2009-05-07 2011-01-20 President And Fellows Of Harvard College Methods and apparatus for fluorescence sensing employing fresnel zone plates
CN102762971B (zh) 2009-11-27 2015-05-27 洛桑联邦理工学院 纳米流体生物传感器及其对于快速测量溶液中的生物分子相互作用的应用及方法
USD673287S1 (en) 2010-11-24 2012-12-25 Sony Corporation Micro flow channel chip
USD673286S1 (en) * 2010-04-29 2012-12-25 Sony Corporation Micro flow channel chip
USD869308S1 (en) 2010-04-29 2019-12-10 Sony Corporation Micro flow channel chip
US9029800B2 (en) 2011-08-09 2015-05-12 Palo Alto Research Center Incorporated Compact analyzer with spatial modulation and multiple intensity modulated excitation sources
US8723140B2 (en) 2011-08-09 2014-05-13 Palo Alto Research Center Incorporated Particle analyzer with spatial modulation and long lifetime bioprobes
EP2920292B1 (de) 2012-11-13 2017-01-11 Agilent Technologies, Inc. Vorrichtung und verfahren für dreidimensionale gewebemessungen auf basis eines kontrollierten medienstroms
GB201312035D0 (en) 2013-07-04 2013-08-21 Cytomos Ltd Biological sensing apparatus
CN116809131A (zh) 2014-06-02 2023-09-29 安捷伦科技有限公司 用于分析生物样本的单列微板系统和载体
JPWO2016063912A1 (ja) 2014-10-24 2017-08-03 国立大学法人 東京大学 粒子検出方法、粒子検出装置および粒子検出システム
JP2018508767A (ja) * 2015-01-30 2018-03-29 ヒューレット−パッカード デベロップメント カンパニー エル.ピー.Hewlett‐Packard Development Company, L.P. マイクロ流体検出
WO2023191806A1 (en) * 2022-04-01 2023-10-05 Hewlett-Packard Development Company, L.P. Cell-isolating dispensers
LU502135B1 (de) * 2022-05-21 2023-11-30 Cytena Gmbh Vorrichtung mit Dispenser zum Dispensieren einer flüssigen Probe

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3705771A (en) * 1970-01-14 1972-12-12 Bio Physics Systems Inc Photoanalysis apparatus
US3661460A (en) * 1970-08-28 1972-05-09 Technicon Instr Method and apparatus for optical analysis of the contents of a sheathed stream
US3992109A (en) * 1973-03-15 1976-11-16 Calspan Corporation Cyclic colorimetry method and apparatus
SE394910B (sv) * 1975-10-29 1977-07-18 Pharmacia Fine Chemicals Ab Sett och anordning for optisk analys
CA1127227A (en) * 1977-10-03 1982-07-06 Ichiro Endo Liquid jet recording process and apparatus therefor
AT377493B (de) * 1979-09-19 1985-03-25 Wiedmer Ernst Schraubverschluss mit einem garantiering fuer einen behaelter zur anzeige der erstmaligen oeffnung des behaelters
JPS576338A (en) * 1980-06-12 1982-01-13 Kyoto Daiichi Kagaku:Kk Method and device for measuring degree of flocculation of finely divided particles quantitatively
JPS5821141A (ja) * 1981-07-30 1983-02-07 Olympus Optical Co Ltd 粒子凝集反応判定方法および判定容器
US4683212A (en) * 1982-09-30 1987-07-28 Technicon Instruments Corporation Random access single channel sheath stream apparatus
US4566791A (en) * 1983-10-31 1986-01-28 Pacific Scientific Company Fluid sample cell comprising Fresnel sectors
US4637729A (en) * 1983-12-14 1987-01-20 Carrier Corporation Fiber optic moisture analysis probe
JP2727316B2 (ja) * 1986-09-12 1998-03-11 株式会社 アドバンス 流体集積素子
US4794806A (en) * 1987-02-13 1989-01-03 Nicoli David F Automatic dilution system
JPS63307332A (ja) * 1987-06-08 1988-12-15 Hitachi Ltd 光計測式生体細胞分析装置
US4867559A (en) * 1988-01-06 1989-09-19 Amoco Corporation Liquid/liquid fiber-optic fluorescence detector and absorbance analyzer
DE3802545A1 (de) * 1988-01-28 1989-08-10 Fraunhofer Ges Forschung Mikropumpe zur foerderung kleinster gasmengen
EP0347579B1 (de) * 1988-06-01 1994-03-30 Daimler-Benz Aerospace Aktiengesellschaft Vorrichtung mit Träger besonderer Struktur zur Aufnahme, Untersuchung und Behandlung von Proben
JP2732685B2 (ja) * 1989-10-31 1998-03-30 株式会社東芝 圧縮機における冷媒溶け込み量検出方法
US4999582A (en) * 1989-12-15 1991-03-12 Boehringer Mannheim Corp. Biosensor electrode excitation circuit
US5171132A (en) * 1989-12-27 1992-12-15 Seiko Epson Corporation Two-valve thin plate micropump
US5183740A (en) * 1990-02-23 1993-02-02 The United States Of America As Represented By The Secretary Of The Navy Flow immunosensor method and apparatus
US5125747A (en) * 1990-10-12 1992-06-30 Tytronics, Inc. Optical analytical instrument and method having improved calibration

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112672641A (zh) * 2018-09-24 2021-04-16 莱利专利股份有限公司 带有检测系统的挤奶系统

Also Published As

Publication number Publication date
DE69217331D1 (de) 1997-03-20
EP0545284B1 (de) 1997-02-05
DE69217331T2 (de) 1997-07-10
EP0545284A1 (de) 1993-06-09
US5370842A (en) 1994-12-06

Similar Documents

Publication Publication Date Title
DE69217331D1 (de) Messvorrichtung und Messystem für Proben
US4865811A (en) Apparatus for automatic chemical analysis
US4920056A (en) Apparatus and method for automated microbatch reaction
US6001231A (en) Methods and systems for monitoring and controlling fluid flow rates in microfluidic systems
US7473400B2 (en) Microfluid handling device
Kim et al. Spatially-resolved fluorescence spectroscopic study on liquid/liquid extraction processes in polymer microchannels
ATE287761T1 (de) Verfahren und vorrichtung zum mischen kleinster flüssigkeitsmengen
DE3874759D1 (de) Rohrbuendelreaktor.
CA2618105A1 (en) Microfluidic reduction of diffusion and complience effect in a fluid mixing region
ATE67860T1 (de) Geraet zur fliess-injektionsanalyse.
BR0207258A (pt) Processo usando modo de condensação em leitos fluidizados, com enriquecimento de fase lìquida e injeção de leito
GB1150501A (en) Improvements in or relating to Devices for Analyzing Liquids Flowing through Capillary Tubes
IT1303451B1 (it) Metodo e dispositivi per migliorare la reazione di combustionedinamica a flash accopppiata alla gascromatografia per l'analisi
EP2420846B1 (de) Chemische Analysevorrichtung
KR930702223A (ko) 과산화산의 제조
ITTO920592A1 (it) Proccedimento per la produzione di ittrio-90 e generatore di ittrio-90
SE8604150D0 (sv) Kernbrenslepatron
DK0419365T3 (da) Indretning til injektion af slam i en forbrændingsovn
KR101174821B1 (ko) 굴절률 변화를 이용한 유체센서 및 이를 이용한 유량 측정방법
US20060034736A1 (en) Microreactor
ATE105733T1 (de) Vorrichtung zum dosieren und mischen von zwei flüssigen komponenten.
KR920014508A (ko) 시약 혼합 방법
SE8801366L (sv) Saett och apparat foer floedesinjektion
GB1150613A (en) A method and apparatus for Determining the Inorganic Carbon Content of Liquids
US7224449B2 (en) Optical fluidic system with a capillary having a drilled through hole