ATE149284T1 - Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen - Google Patents

Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen

Info

Publication number
ATE149284T1
ATE149284T1 AT91909847T AT91909847T ATE149284T1 AT E149284 T1 ATE149284 T1 AT E149284T1 AT 91909847 T AT91909847 T AT 91909847T AT 91909847 T AT91909847 T AT 91909847T AT E149284 T1 ATE149284 T1 AT E149284T1
Authority
AT
Austria
Prior art keywords
lyophilized
new compositions
cells
restored cells
matter
Prior art date
Application number
AT91909847T
Other languages
English (en)
Inventor
Raymond P Goodrich Jr
Victoria A Wong
Original Assignee
Cobe Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Lab filed Critical Cobe Lab
Application granted granted Critical
Publication of ATE149284T1 publication Critical patent/ATE149284T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/124—Disinfecting agents, e.g. antimicrobials
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91909847T 1990-05-17 1991-05-17 Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen ATE149284T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/525,392 US5213814A (en) 1989-04-10 1990-05-17 Lyophilized and reconstituted blood platelet compositions

Publications (1)

Publication Number Publication Date
ATE149284T1 true ATE149284T1 (de) 1997-03-15

Family

ID=24093064

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91909847T ATE149284T1 (de) 1990-05-17 1991-05-17 Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen

Country Status (10)

Country Link
US (1) US5213814A (de)
EP (1) EP0483329B1 (de)
JP (1) JPH05500231A (de)
AT (1) ATE149284T1 (de)
AU (1) AU7888391A (de)
CA (1) CA2064228C (de)
DE (1) DE69124915D1 (de)
IL (1) IL98182A0 (de)
WO (1) WO1991017655A1 (de)
ZA (1) ZA913774B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5428008A (en) * 1989-04-14 1995-06-27 Prp, Inc. Therapeutic composition of micellar structures capable of promoting hemotasis
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US6187572B1 (en) * 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
JPH05501419A (ja) * 1990-05-25 1993-03-18 コーブ　ラボラトリーズ　インコーポレイテッド 生体適合性、両親媒性ポリマー混合物中の細胞、細胞―様物質および小板の凍結乾燥法
US5569579A (en) * 1991-04-01 1996-10-29 Thomas Jefferson University Synthetic-based platelet storage media
US5376524A (en) * 1991-04-01 1994-12-27 Thomas Jefferson University Platelet storage medium containing acetate and phosphate
DE69333924T2 (de) * 1992-05-29 2006-08-17 University Of North Carolina At Chapel Hill Im immobilisierten Zustand getrocknete pharmazeutisch verträgliche menschliche Blutplättchen
US5690963A (en) * 1995-06-30 1997-11-25 The United States Of America As Represented By The Secretary Of The Navy Freeze dried red blood cells
US5736313A (en) * 1995-10-20 1998-04-07 The United States Of America As Represented By The Secretary Of The Navy Method of lyophilizing platelets by incubation with high carbohydrate concentrations and supercooling prior to freezing
US5891692A (en) 1996-03-29 1999-04-06 Life Technologies, Inc. Method for increasing the viability and transformation ability of bacteria during or after storage at low temperatures
DE19634313A1 (de) * 1996-08-24 1998-02-26 Behringwerke Ag Methode zur Stabilisierung von Plättchen
DK1005529T3 (da) 1997-02-12 2005-06-13 Invitrogen Corp Fremgangsmåder til lyofilisering af kompetente celler
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
US6139878A (en) * 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
US6413713B1 (en) 1998-10-30 2002-07-02 Hyperbaric Systems Method for preserving blood platelets
AU6875900A (en) * 1999-09-08 2001-04-10 Chugai Seiyaku Kabushiki Kaisha Protein solution preparation and method of stabilizing the same
DE10085291T1 (de) 1999-12-21 2003-05-08 Bioenergy Inc Zusammensetzungen für die Lagerung von Blutplättchen
US6770478B2 (en) 2000-02-10 2004-08-03 The Regents Of The University Of California Erythrocytic cells and method for preserving cells
CA2397362A1 (en) * 2000-02-10 2001-08-16 The Regents Of The University Of California Therapeutic platelets and methods
EP1399018A1 (de) * 2001-06-26 2004-03-24 Human Biosystems Konservierung von blutplättchen bei kalten temperaturen
GB0230152D0 (en) * 2002-12-24 2003-02-05 Sinvent As Product
CA2522941A1 (en) 2003-04-23 2004-11-04 Human Biosystems Improved methods and solutions for storing donor organs
US20040229205A1 (en) * 2003-05-16 2004-11-18 Ericson Daniel G. Compositions for the storage of platelets
JP2007501255A (ja) 2003-08-04 2007-01-25 ヒューマン バイオシステムズ 血液細胞の保存
CN101072506B (zh) 2004-08-12 2010-05-12 塞尔菲乐有限公司 制备冻干血小板的方法、包括冻干血小板的组合物和使用方法
KR101368924B1 (ko) 2005-11-17 2014-03-04 니뽄젠야쿠코교 가부시키가이샤 세포 보존용 수용액
US20090117057A1 (en) * 2007-11-06 2009-05-07 Shanbrom Technologies, Llc Grape Polyphenolics for Platelet and Bacterial Control
AU2013365623B2 (en) 2012-12-20 2017-08-24 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture
JP6659591B2 (ja) 2014-06-09 2020-03-04 テルモ ビーシーティー、インコーポレーテッド 凍結乾燥
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー 凍結乾燥方法
CA3121200A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
WO2020112963A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
CN113597532B (zh) 2019-03-14 2023-02-17 泰尔茂比司特生物技术有限公司 冻干容器填充固定装置、系统及使用方法
IL322149A (en) 2019-05-03 2025-09-01 Cellphire Inc Materials and methods for manufacturing blood products
CN114450066A (zh) 2019-08-16 2022-05-06 塞尔菲乐有限公司 作为抗血小板剂逆转剂的血栓小体
CA3170196A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc. Anti-fibrinolytic loaded platelets
TW202245814A (zh) 2021-02-17 2022-12-01 美商賽菲爾公司 用於治療抗血小板誘導的凝血病之凍乾血小板衍生物組成物
CN114617903B (zh) * 2022-03-15 2024-05-24 中国人民解放军总医院第一医学中心 一种用于血浆冻干的组合物及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786014A (en) * 1952-09-10 1957-03-19 James L Tullis Platelet preservation
US3303662A (en) * 1963-03-01 1967-02-14 Union Carbide Corp Process for cell preservation
BE643051A (de) * 1963-05-31 1964-05-15
DE2546166A1 (de) * 1975-10-15 1977-04-28 Behringwerke Ag Gegerbte thrombozyten
US4059967A (en) * 1976-02-19 1977-11-29 The Community Blood Council Of Greater New York, Inc. Process for freezing blood platelets
US4961928A (en) * 1986-03-19 1990-10-09 American Red Cross Synthetic, plasma-free, transfusible storage medium for red blood cells and platelets
US4764463A (en) * 1986-10-30 1988-08-16 The University Of Tennessee Research Corporation Platelet cyropreservation
US5153004A (en) * 1989-06-02 1992-10-06 Cryopharm Corporation Freezing and thawing of erythrocytes
US5178884A (en) * 1988-05-18 1993-01-12 Cryopharm Corporation Lyophilized and reconstituted red blood cell compositions
EP0356258A3 (de) * 1988-08-26 1990-06-06 Cryopharm Corporation Gefriertrocknungsmethode für rote Blutkörperchen und Mittel dafür
US4874690A (en) * 1988-08-26 1989-10-17 Cryopharm Corporation Lyophilization of red blood cells
US4973327A (en) * 1989-11-01 1990-11-27 Cryopharm Blood bag for lyophilization
AU653337B2 (en) * 1990-04-16 1994-09-29 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
JPH05501419A (ja) * 1990-05-25 1993-03-18 コーブ　ラボラトリーズ　インコーポレイテッド 生体適合性、両親媒性ポリマー混合物中の細胞、細胞―様物質および小板の凍結乾燥法
CA2078004A1 (en) * 1991-02-15 1992-08-16 Christine M. Williams Method of lyophilization and reconstitution of mixtures of nucleated non-mammalian cells and blood matter

Also Published As

Publication number Publication date
US5213814A (en) 1993-05-25
CA2064228A1 (en) 1991-11-18
WO1991017655A1 (en) 1991-11-28
CA2064228C (en) 1999-04-06
DE69124915D1 (de) 1997-04-10
ZA913774B (en) 1992-02-26
JPH05500231A (ja) 1993-01-21
AU7888391A (en) 1991-12-10
IL98182A0 (en) 1992-06-21
EP0483329A4 (en) 1993-08-11
EP0483329B1 (de) 1997-03-05
EP0483329A1 (de) 1992-05-06

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