ATE149310T1 - Methode und lösung zur bestimmung der wirkungsdauer einer auf die hornhaut aufgebrachten substanz - Google Patents
Methode und lösung zur bestimmung der wirkungsdauer einer auf die hornhaut aufgebrachten substanzInfo
- Publication number
- ATE149310T1 ATE149310T1 AT92921102T AT92921102T ATE149310T1 AT E149310 T1 ATE149310 T1 AT E149310T1 AT 92921102 T AT92921102 T AT 92921102T AT 92921102 T AT92921102 T AT 92921102T AT E149310 T1 ATE149310 T1 AT E149310T1
- Authority
- AT
- Austria
- Prior art keywords
- formulation
- eye
- fluorescently labelled
- thin film
- cornea
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 7
- 239000000203 mixture Substances 0.000 abstract 7
- 239000010409 thin film Substances 0.000 abstract 3
- 206010023644 Lacrimation increased Diseases 0.000 abstract 1
- 230000004397 blinking Effects 0.000 abstract 1
- 230000004317 lacrimation Effects 0.000 abstract 1
- 229920002521 macromolecule Polymers 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/13—Ophthalmic microscopes
- A61B3/135—Slit-lamp microscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
- A61B3/1241—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes specially adapted for observation of ocular blood flow, e.g. by fluorescein angiography
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Eye Examination Apparatus (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/759,530 US5323775A (en) | 1991-09-13 | 1991-09-13 | Diagnostic method for determining precorneal retention time of ophthalmic formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE149310T1 true ATE149310T1 (de) | 1997-03-15 |
Family
ID=25056002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92921102T ATE149310T1 (de) | 1991-09-13 | 1992-09-08 | Methode und lösung zur bestimmung der wirkungsdauer einer auf die hornhaut aufgebrachten substanz |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5323775A (de) |
| EP (1) | EP0603338B1 (de) |
| AT (1) | ATE149310T1 (de) |
| AU (1) | AU2670892A (de) |
| DE (1) | DE69217969T2 (de) |
| ES (1) | ES2100362T3 (de) |
| WO (1) | WO1993005699A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT101290B (pt) * | 1993-06-18 | 2000-10-31 | Fernandes Jose Guilherme Da Cu | Fluorometro para medicao da concentracao de fluoroforos de localizacao ocular |
| US5553617A (en) * | 1995-01-20 | 1996-09-10 | Hughes Aircraft Company | Noninvasive method and apparatus for determining body chemistry |
| US6179779B1 (en) | 1997-12-22 | 2001-01-30 | Ffhk Development Company Llc | Replaceable prism system for applanation tonometer |
| US6736778B2 (en) | 1997-12-22 | 2004-05-18 | Francis Y. Falck, Jr. | Replaceable prism for applanation tonometer |
| JP2004500197A (ja) | 2000-02-08 | 2004-01-08 | コーネル リサーチ ファンデーション インコーポレーテッド | 光ファイバーを通じた蛍光分光用の多光子励起 |
| AU2002251682A1 (en) * | 2000-11-02 | 2002-08-28 | Cornell Research Foundation, Inc. | In vivo multiphoton diagnostic detection and imaging of a neurodegenerative disease |
| JP4823906B2 (ja) * | 2003-08-19 | 2011-11-24 | コーネル リサーチ ファンデーション インコーポレーティッド | 多光子顕微鏡観察、分光法、および内視鏡観察などの生物学的用途のための光ファイバー送集光システム |
| US20070089231A1 (en) * | 2005-10-24 | 2007-04-26 | Fendall, Inc. | Emergency eyewash station having a peircing mechanism to puncture a sealed fluid bladder |
| WO2007050524A1 (en) * | 2005-10-24 | 2007-05-03 | Sperian Eye & Face Protection, Inc. | Pump assembly for an emergency eyewash station |
| WO2007050525A1 (en) * | 2005-10-24 | 2007-05-03 | Sperian Eye & Face Protection, Inc. | Emergency eyewash station having an expandable bellows waste collection system |
| US8316477B2 (en) * | 2005-10-24 | 2012-11-27 | Sperian Eye & Face Protection, Inc. | Cartridge assembly for a self-contained emergency eyewash station |
| US8313472B2 (en) * | 2006-03-15 | 2012-11-20 | Sperian Eye & Face Protection, Inc. a Delaware corporation | Emergency eyewash station and dispensing structure therefor |
| AU2008247423B2 (en) | 2007-05-04 | 2013-10-31 | Abbott Medical Optics Inc. | Methods and devices for measuring tear film and diagnosing tear disorders |
| US7989404B2 (en) * | 2008-02-11 | 2011-08-02 | Clearwater International, Llc | Compositions and methods for gas well treatment |
| GB2493568B (en) * | 2011-08-09 | 2018-08-29 | Zeiss Carl Meditec Ag | Opthalmologic composition comprising an aqueous solution of at least one viscoelastic polysaccharide |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4003991A (en) * | 1974-08-27 | 1977-01-18 | National Patent Development Corporation | Ophthalmic formulation |
| US4120792A (en) * | 1977-08-15 | 1978-10-17 | Thiokol Corporation | Combined filter and incinerator |
| US4120949A (en) * | 1977-10-05 | 1978-10-17 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4409205A (en) * | 1979-03-05 | 1983-10-11 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4407792A (en) * | 1979-05-09 | 1983-10-04 | Alcon Laboratories, Inc. | Sustained release ophthalmic drug dosage |
| US4597965A (en) * | 1979-06-06 | 1986-07-01 | Holles Laboratories, Inc. | Method and composition for controlling corneal hydration |
| US4412543A (en) * | 1981-04-09 | 1983-11-01 | Xanar, Inc. | Apparatus for determining the concentration of a fluorescent material in an eye |
| US5025785A (en) * | 1982-09-10 | 1991-06-25 | Weiss Jeffrey N | Diabetes detection method |
| US4883351A (en) * | 1982-09-10 | 1989-11-28 | Weiss Jeffrey N | Apparatus for the detection of diabetes and other abnormalities affecting the lens of the eye |
| US4895159A (en) * | 1982-09-10 | 1990-01-23 | Weiss Jeffrey N | Diabetes detection method |
| US4540568A (en) * | 1982-10-14 | 1985-09-10 | Trager Seymour F | Injectionable viscoelastic ophthalmic gel |
| US4573778A (en) * | 1983-03-16 | 1986-03-04 | Boston University | Aqueous fluorophotometer |
| US4594326A (en) * | 1983-05-09 | 1986-06-10 | Wade Stephen E | Time-integrated measurement for determining substances in biological fluids |
| US4474751A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Ophthalmic drug delivery system utilizing thermosetting gels |
| US4711540A (en) * | 1984-01-04 | 1987-12-08 | Tokyo Kogaku Kikai Kabushiki Kaisha | Eye disease inspecting instrument |
| US4711541A (en) * | 1984-02-02 | 1987-12-08 | Tokyo Kogaku Kikai Kabushiki Kaisha | Slit lamp and accessory device thereof |
| SE454842B (sv) * | 1984-11-01 | 1988-06-06 | Pharmacia Ab | Komposition for anvendning vid oftalmologiska applikationer innehallande en vattenlosning av en hogmolekyler polymer och ett lost polymert fergemne |
| US4702576A (en) * | 1985-09-27 | 1987-10-27 | Cambridge Instruments Inc. | Ocular scattering analyzer |
| DE3542167A1 (de) * | 1985-11-29 | 1987-06-04 | Wolfgang Prof Dr Lohmann | Verfahren zur messung der augen-linsen-truebung und anordnung zur durchfuehrung des verfahrens |
| CH671329A5 (de) * | 1986-01-21 | 1989-08-31 | Interzeag Ag | |
| US4883658A (en) * | 1986-04-28 | 1989-11-28 | Holly Frank J | Ophthalmic solution for treatment of dry-eye syndrome |
| US4744980A (en) * | 1986-04-28 | 1988-05-17 | Holly Frank J | Ophthalmic solution for treatment of dry eye syndrome |
| US4966773A (en) * | 1986-11-25 | 1990-10-30 | Alcon Laboratories, Inc. | Topical ophthalmic compositions containing microfine retinoid particles |
| US4842401A (en) * | 1987-06-15 | 1989-06-27 | The Board Of Trustees Of The Leland Stanford Jr. University | Eye diagnosis process |
| US5171526A (en) * | 1990-01-05 | 1992-12-15 | Allergan, Inc. | Ophthalmic compositions and methods for preserving and using same |
-
1991
- 1991-09-13 US US07/759,530 patent/US5323775A/en not_active Expired - Fee Related
-
1992
- 1992-09-08 AU AU26708/92A patent/AU2670892A/en not_active Abandoned
- 1992-09-08 AT AT92921102T patent/ATE149310T1/de not_active IP Right Cessation
- 1992-09-08 ES ES92921102T patent/ES2100362T3/es not_active Expired - Lifetime
- 1992-09-08 WO PCT/US1992/007567 patent/WO1993005699A1/en not_active Ceased
- 1992-09-08 EP EP92921102A patent/EP0603338B1/de not_active Expired - Lifetime
- 1992-09-08 DE DE69217969T patent/DE69217969T2/de not_active Expired - Fee Related
-
1993
- 1993-12-30 US US08/176,768 patent/US5634458A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0603338A1 (de) | 1994-06-29 |
| DE69217969D1 (de) | 1997-04-10 |
| EP0603338B1 (de) | 1997-03-05 |
| US5323775A (en) | 1994-06-28 |
| US5634458A (en) | 1997-06-03 |
| ES2100362T3 (es) | 1997-06-16 |
| WO1993005699A1 (en) | 1993-04-01 |
| AU2670892A (en) | 1993-04-27 |
| DE69217969T2 (de) | 1997-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE149310T1 (de) | Methode und lösung zur bestimmung der wirkungsdauer einer auf die hornhaut aufgebrachten substanz | |
| ATE76288T1 (de) | Feste pharmaceutische zubereitung mit verlaengerter wirkstofffreigabe und verfahren zur herstellung. | |
| ATE89723T1 (de) | Retinoide zur behandlung lichtgeschaedigter haut. | |
| ATE133336T1 (de) | Verwendung von rapamycin zur herstellung eines arzneimittels zur behandlung von augenentzündungen | |
| ATE61935T1 (de) | Verfahren zur herstellung von mikrokapseln. | |
| FR2422402A1 (fr) | Composition a base d'ester 3-b-methoxyethylique et 5-isopropylique de 1,4-dihydro-2,6-dimethyl-4-(3'-nitrophenyl) pyridine, destinee a la therapeutique cerebrale | |
| ATE103914T1 (de) | Neue thienylcarbonsaeureester von aminoalkoholen, ihre quaternierungsprodukte sowie die herstellung und verwendung dieser verbindungen. | |
| ATE29207T1 (de) | Beleuchtungseinrichtung zum sichtbaren nachweis von karies. | |
| BG92179A (bg) | Метод за получаване на 7-заместена-хепт-6-еноена и -хептаноена киселина и техни производни и междинни съединения | |
| ATE191849T1 (de) | Verwendung von (s)-(-)-alpha-ethyl-2-oxo-1- pyrrolidinacetamid zur herstellung eines medikaments zur behandlung von angst | |
| BG46600A3 (en) | Method for preparing derivatives of dihydrobenzofuran and of chromancarboxamides | |
| ATA540478A (de) | Verfahren zur herstellung von optisch aktiven alpha-hydroxycarbonsaeuren | |
| AT363936B (de) | Verfahren zur herstellung von neuen cyproheptadinderivaten und von deren pharmazeutisch verwendbaren salzen sowie optischen isomeren | |
| DE3764700D1 (de) | Verfahren zur herstellung einer waessrigen pharmazeutischen loesung einer organischen saeure als wirkstoff. | |
| SE8801710L (sv) | New ophtalmological composition of matter | |
| PT88383A (pt) | Verfahren fuer die herstellung von 2-[4-<2-(4-chlorbenzamido)-ethyl-phenoxy]-2-methylpropionsaeure enthaltenden pharmazeutischen zusammensetzungen zur behandlung von diabetes geeignet | |
| ATE116849T1 (de) | Pharmazeutische verwendung von fettsäuren. | |
| ATA147676A (de) | Verfahren zur herstellung von reiner traubensaure und von mesoweinsaure | |
| DE69115687D1 (de) | Verwendung von spezifischen Fettsäuren zur Herstellung eines Medikaments zur Verabreichung durch Iontophorese | |
| DE3862017D1 (de) | Pharmazeutische zubereitung zur behandlung von tinea pedis. | |
| FR2390157A1 (fr) | Produit et procede pour le traitement de l'ivoire dentaire par le cerium | |
| DE3686097D1 (de) | Verwendung von dopamin-agonisten zur herstellung eines arzneimittels zur behandlung von psychostimulant-sucht. | |
| ATE49402T1 (de) | Verfahren zur herstellung von zirkoniumcarboxylat. | |
| ATE122886T1 (de) | Verwendung von 1,4-dihydropyridin-derivaten in der behandlung von alkoholsucht. | |
| DE3881484D1 (de) | Optisch aktive produkte von 20,21-dinoreburnamenin-derivaten, verfahren zur herstellung, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammenstellungen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |