ATE149846T1 - Apparat zur einbringung von medikamenten in rote blutkörperchen - Google Patents

Apparat zur einbringung von medikamenten in rote blutkörperchen

Info

Publication number
ATE149846T1
ATE149846T1 AT92915621T AT92915621T ATE149846T1 AT E149846 T1 ATE149846 T1 AT E149846T1 AT 92915621 T AT92915621 T AT 92915621T AT 92915621 T AT92915621 T AT 92915621T AT E149846 T1 ATE149846 T1 AT E149846T1
Authority
AT
Austria
Prior art keywords
suspension
unit
resealing
pct
temperature
Prior art date
Application number
AT92915621T
Other languages
English (en)
Inventor
Etienne Pages
Christophe Bailleul
Claude Ropars
Original Assignee
Europ Communities
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europ Communities filed Critical Europ Communities
Application granted granted Critical
Publication of ATE149846T1 publication Critical patent/ATE149846T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692—Washing or rinsing blood or blood constituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/369—Temperature treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0429—Red blood cells; Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/366—General characteristics of the apparatus related to heating or cooling by liquid heat exchangers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Centrifugal Separators (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
AT92915621T 1991-07-03 1992-07-02 Apparat zur einbringung von medikamenten in rote blutkörperchen ATE149846T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9108302A FR2678512B1 (fr) 1991-07-03 1991-07-03 Machine a internaliser.

Publications (1)

Publication Number Publication Date
ATE149846T1 true ATE149846T1 (de) 1997-03-15

Family

ID=9414655

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92915621T ATE149846T1 (de) 1991-07-03 1992-07-02 Apparat zur einbringung von medikamenten in rote blutkörperchen

Country Status (13)

Country Link
US (1) US5589389A (de)
EP (1) EP0679101B1 (de)
JP (1) JP3148239B2 (de)
AT (1) ATE149846T1 (de)
CA (1) CA2112685A1 (de)
DE (1) DE69218265T2 (de)
DK (1) DK0679101T3 (de)
ES (1) ES2098519T3 (de)
FI (1) FI935940L (de)
FR (1) FR2678512B1 (de)
GR (1) GR3023360T3 (de)
NO (1) NO306327B1 (de)
WO (1) WO1993000940A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882448B1 (de) * 1997-05-05 2005-01-12 DIDECO S.r.l. Verfahren zur Verkapselung von biologisch aktiven Stoffen in Erythrocyten und Gerät dafür
EP1857547B2 (de) 2002-08-05 2020-12-02 Silence Therapeutics GmbH Weitere neue Formen von interferierenden RNA-Molekülen
FR2873925B1 (fr) * 2004-08-05 2006-10-13 Erytech Pharma Soc Par Actions Procede et dispositif de lyse-rescellement pour l'incorporation de principe actif notamment asparaginase ou inositol hexaphosphate, dans des erythrocytes
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
FR2919804B1 (fr) 2007-08-08 2010-08-27 Erytech Pharma Composition et vaccin therapeutique anti-tumoral
ES2405258T3 (es) * 2008-02-13 2013-05-30 Erytech Pharma Formulación y procedimiento para la prevención y el tratamiento de la manifestación esquelética de la enfermedad de Gaucher
FR2928270B1 (fr) * 2008-03-10 2011-01-21 Erytech Pharma Formulation methode pour la prevention ou le traitement des metastases osseuses et autres maladies de l'os
FR2940087B1 (fr) 2008-12-18 2011-05-06 Lab Francais Du Fractionnement Erythrocytes contenant du facteur viii, preparation et utilisations.
IT1399590B1 (it) * 2010-04-26 2013-04-26 Erydel Spa Apparato e kit per incapsulare almeno un composto ad uso terapeutico e/o diagnostico all'interno di eritrociti
US20150086521A1 (en) 2012-03-21 2015-03-26 Erytech Pharma Medicament for the Treatment of Acute Myeloid Leukemia (AML)
FR3005420B1 (fr) 2013-05-07 2015-09-18 Erytech Pharma Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues.
EP2813234A1 (de) 2013-06-11 2014-12-17 Erytech Pharma Zusammensetzung basierend auf Erythrocyten, in die Phenylalanin-Hydroxylase verkapselt ist, und therapeutische Verwendungen davon
US11613759B2 (en) 2015-09-04 2023-03-28 Sqz Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
CN109415741A (zh) 2016-05-03 2019-03-01 Sqz生物技术公司 细胞内递送生物分子以诱导耐受性
IT202100023375A1 (it) * 2021-09-09 2023-03-09 Yang Shunfa Dispositivo per la produzione di vescicole bioingegnerizzate dedicate e metodo correlato

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1501134B2 (de) * 1966-02-02 1976-08-12 Siemens AG, 1000 Berlin und 8000 München Vorrichtung zur veraenderung der temperatur von blut
US3839204A (en) * 1972-04-27 1974-10-01 Gen Electric Integral blood heat and component exchange device and two flow path membrane blood gas exchanger
US3853479A (en) * 1972-06-23 1974-12-10 Sherwood Medical Ind Inc Blood oxygenating device with heat exchanger
US4327710A (en) * 1980-06-18 1982-05-04 The United States Of America As Represented By The Secretary Of Agriculture Process for encapsulating additives in resealed erythrocytes for disseminating chemicals via the circulatory system
US4517080A (en) * 1980-06-18 1985-05-14 The United States Of America As Represented By The Secretary Of Agriculture Apparatus for encapsulating additives in resealed erythrocytes
FR2529463B1 (fr) * 1982-07-05 1986-01-10 Centre Nat Rech Scient Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus
US4668214A (en) * 1986-06-09 1987-05-26 Electromedics, Inc. Method of washing red blood cells
NL8701233A (nl) * 1987-05-22 1988-12-16 Medistad Holland Bloedverwarmingstoestel.

Also Published As

Publication number Publication date
US5589389A (en) 1996-12-31
FI935940A0 (fi) 1993-12-30
NO934899L (no) 1994-03-01
JPH06509250A (ja) 1994-10-20
FI935940A7 (fi) 1994-02-17
FR2678512A1 (fr) 1993-01-08
DK0679101T3 (da) 1997-09-22
JP3148239B2 (ja) 2001-03-19
DE69218265T2 (de) 1997-08-14
NO934899D0 (no) 1993-12-29
NO306327B1 (no) 1999-10-25
ES2098519T3 (es) 1997-05-01
WO1993000940A1 (fr) 1993-01-21
GR3023360T3 (en) 1997-08-29
EP0679101B1 (de) 1997-03-12
CA2112685A1 (fr) 1993-01-21
FI935940L (fi) 1994-02-17
DE69218265D1 (de) 1997-04-17
FR2678512B1 (fr) 1995-06-30
EP0679101A1 (de) 1995-11-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee