ATE150304T1 - Tricyclische verbindungen enthaltende salben - Google Patents

Tricyclische verbindungen enthaltende salben

Info

Publication number: ATE150304T1
Authority: AT; Austria
Prior art keywords: tricyclic compounds; ointments containing; containing tricyclic; ointment; octacos
Prior art date: 1990-09-04

Application number

AT91114598T

Other languages

English (en)

Inventor

Sotoo Asakura

Yoshio Murakami

Nobuto Kanagawa

Toshiomi Nakate

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-04

Filing date

1991-08-30

Publication date

1997-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16982211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE150304(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-08-30 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1997-04-15 Application granted granted Critical

1997-04-15 Publication of ATE150304T1 publication Critical patent/ATE150304T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 2
239000002674 ointment Substances 0.000 title abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 1
CFZGEMKIQUVTCC-UHFFFAOYSA-N octacos-18-ene-2,3,10,16-tetrone Chemical compound CCCCCCCCCC=CCC(=O)CCCCCC(=O)CCCCCCC(=O)C(C)=O CFZGEMKIQUVTCC-UHFFFAOYSA-N 0.000 abstract 1
239000003883 ointment base Substances 0.000 abstract 1
208000017520 skin disease Diseases 0.000 abstract 1
230000003381 solubilizing effect Effects 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
229920002554 vinyl polymer Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Transplantation (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT91114598T 1990-09-04 1991-08-30 Tricyclische verbindungen enthaltende salben ATE150304T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP23517790		1990-09-04

Publications (1)

Publication Number	Publication Date
ATE150304T1 true ATE150304T1 (de)	1997-04-15

Family

ID=16982211

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91114598T ATE150304T1 (de)	1990-09-04	1991-08-30	Tricyclische verbindungen enthaltende salben

Country Status (19)

Country	Link
US (1)	US5385907A (de)
EP (1)	EP0474126B1 (de)
JP (1)	JP2526752B2 (de)
KR (1)	KR100194240B1 (de)
CN (1)	CN1069193C (de)
AT (1)	ATE150304T1 (de)
AU (1)	AU656145B2 (de)
CA (1)	CA2050623C (de)
DE (1)	DE69125230T2 (de)
DK (1)	DK0474126T3 (de)
ES (1)	ES2099112T3 (de)
GR (1)	GR3022883T3 (de)
HU (2)	HUT59002A (de)
IE (1)	IE913085A1 (de)
PH (1)	PH31282A (de)
PT (1)	PT98862B (de)
RU (1)	RU2079303C1 (de)
SG (1)	SG46547A1 (de)
ZA (1)	ZA916983B (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2134860T3 (es) *	1992-11-18	1999-10-16	Fujisawa Pharmaceutical Co	Preparacion farmaceutica de accion prolongada.
JPH06345646A (ja) *	1993-06-08	1994-12-20	Fujisawa Pharmaceut Co Ltd	ローション剤
DK0786986T3 (da) *	1994-10-26	2002-04-29	Novartis Ag	Anvendelse af en umættet fedtalkohol
AU735106B2 (en) *	1994-10-26	2001-06-28	Novartis Ag	Pharmaceutical compositions
GB2327611B (en) *	1994-10-26	1999-06-02	Novartis Ag	Macrolide compositions
DE19549794B4 (de) *	1994-10-26	2009-07-30	Novartis Ag	Pharmazeutische Zusammensetzungen
GB2327610B (en) *	1994-11-04	1999-06-02	Novartis Ag	Macrolide compositions
AR004480A1 (es) *	1995-04-06	1998-12-16	Amico Derin C D	Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
US5993787A (en) *	1996-09-13	1999-11-30	Johnson & Johnson Consumer Products, Inc.	Composition base for topical therapeutic and cosmetic preparations
AU5340298A (en) *	1996-12-27	1998-07-31	Takeda Chemical Industries Ltd.	Stabilized tricyclic compound
TW450810B (en) *	1997-02-20	2001-08-21	Fujisawa Pharmaceutical Co	Macrolides antibiotic pharmaceutical composition for preventing and treating skin diseases
GB9723669D0 (en) *	1997-11-07	1998-01-07	Univ Aberdeen	Skin penetration enhancing components
RU2149635C1 (ru) *	1998-02-27	2000-05-27	Пермская государственная медицинская академия	Способ лечения аллергических дерматитов
TR200003108T2 (tr) *	1998-04-27	2001-02-21	Fujisawa Pharmaceutical Co., Ltd.	İlaç kompozisyonları
GB9817064D0 (en) *	1998-08-05	1998-10-07	Fujisawa Pharmaceutical Co	New use
US6300341B1 (en)	1998-09-30	2001-10-09	The Procter & Gamble Co.	2-substituted heterocyclic sulfonamides
US6307049B1 (en)	1998-09-30	2001-10-23	The Procter & Gamble Co.	Heterocyclic 2-substituted ketoamides
GB9826656D0 (en) *	1998-12-03	1999-01-27	Novartis Ag	Organic compounds
AUPR529701A0 (en) *	2001-05-28	2001-06-21	Fujisawa Pharmaceutical Co., Ltd.	Pharmaceutical composition
RU2183113C1 (ru) *	2001-06-28	2002-06-10	Новицкий Юрий Алексеевич	Средство-гидросульфат графита и способ лечения больных с доброкачественными и злокачественными опухолями кожи (варианты)
EP1406700A1 (de)	2001-07-06	2004-04-14	Sucampo AG	Zurbereitung zur topischen anwendung enthaltend einen interleukin-2 inhibitor und eine antimikrobielle substanz
AR038628A1 (es) *	2002-03-04	2005-01-19	Novartis Ag	Composicion oftalmica
CN101897662B (zh) *	2002-07-23	2013-05-22	诺瓦提斯公司	包含药物、软膏基质和增溶剂/分散剂的眼用软膏剂组合物
GB0218996D0 (en) *	2002-08-14	2002-09-25	Novartis Ag	Organic compounds
RU2231359C1 (ru) *	2002-12-11	2004-06-27	Государственное образовательное учреждение высшего профессионального образования Московская медицинская академия им. И.М.Сеченова	Способ лечения язвенных форм ангиитов кожи
EP2377532A1 (de) *	2004-08-18	2011-10-19	Ace ApS	Kosmetische und pharmazeutische Zusammensetzungen mit ACE-Hemmern und/oder Angiotensin-II-Rezeptorantagonisten zur Behandlung von Hauterkrankungen
AU2005232248B2 (en) *	2005-01-04	2011-08-04	Texas United Chemical Company, Llc	Compounded hydrocarbon oil and oil base drilling fluids prepared therefrom
EP1852120A1 (de) *	2005-02-14	2007-11-07	Taisho Pharmaceutical Co., Ltd	Salbe
WO2006098353A1 (ja) *	2005-03-15	2006-09-21	Kyowa Hakko Kogyo Co., Ltd.	外用剤
BRPI0616898A2 (pt) *	2005-10-05	2011-07-05	Mitsubishi Tanabe Pharma Corp	agente de tratamento de dermatite tópica e uso do mesmo
WO2007097317A1 (ja)	2006-02-21	2007-08-30	Eisai R & D Management Co., Ltd.	４－（３－ベンゾイルアミノフェニル）－６，７－ジメトキシ－２－メチルアミノキナゾリン誘導体
US8530654B2 (en)	2007-02-16	2013-09-10	Eisai R&D Management Co., Ltd.	Crystals, amorphous substances or salts of methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl) phenyl] terephthalamic acid
US10265265B2 (en)	2007-03-15	2019-04-23	Drug Delivery Solutions Limited	Topical composition
ATE538102T1 (de)	2007-08-17	2012-01-15	Eisai R&D Man Co Ltd	Verfahren zur herstellung eines chinazolinderivats
CN101687819B (zh)	2007-08-17	2013-03-20	卫材R&D管理有限公司	外用剂
CA2738831C (en)	2008-10-08	2016-05-24	Takata Seiyaku Co., Ltd.	Tacrolimus preparation for external applications
JP2010132607A (ja) *	2008-12-05	2010-06-17	Taisho Pharm Ind Ltd	アトピー性皮膚炎治療用軟膏剤
JP2010202546A (ja) *	2009-03-02	2010-09-16	Taisho Pharm Ind Ltd	アトピー性皮膚炎の治療用軟膏製剤
JP5652795B2 (ja) *	2011-01-31	2015-01-14	国立大学法人大阪大学	皮膚疾患を処置するための外用薬およびその製造方法
CN102885761B (zh) *	2012-09-24	2015-08-05	浙江万晟药业有限公司	一种制备他克莫司软膏的方法
RU2538680C2 (ru) *	2013-03-12	2015-01-10	Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН")	Фармацевтическая композиция для лечения атопического дерматита и способ ее получения
RU2553600C2 (ru) *	2013-05-16	2015-06-20	Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН")	Фармацевтическая композиция для лечения заболеваний кожи
CN104127369A (zh) *	2014-07-02	2014-11-05	人福医药集团股份公司	他克莫司软膏及其制备方法
US10143682B2 (en)	2014-10-28	2018-12-04	Koushi Yamaguchi	Medicine for improving state of pregnancy, and use thereof
CN106309353A (zh) *	2015-06-19	2017-01-11	江苏吉贝尔药业股份有限公司	一种治疗银屑病的软膏剂及其制备方法
CN109069418B (zh)	2016-04-04	2026-03-13	Mc2疗法有限公司	包含他克莫司的局部组合物
CN105769752B (zh) *	2016-04-08	2018-12-11	湖北人福成田药业有限公司	制备他克莫司软膏的方法及他克莫司软膏
EP3542788A1 (de)	2018-03-19	2019-09-25	MC2 Therapeutics Limited	Topische zusammensetzung enthaltend calcipotriol und betamethason dipropionat
AU2019318035A1 (en)	2018-08-10	2021-03-04	Koushi Yamaguchi	Therapeutic agent for humoral immunity-related diseases in materno-fetal relationship
WO2020117134A1 (en) *	2018-12-04	2020-06-11	İlko İlaç Sanayi̇ Ve Ti̇caret A.Ş.	Stable tacrolimus ointment formulation for topical treatment of skin conditions
CN113226331A (zh)	2018-12-18	2021-08-06	山口晃史	用于改善不孕不育症或妊娠状态的药物
CN112439071B (zh) *	2019-09-04	2022-05-20	武汉科福新药有限责任公司	透皮促渗组合物及其在噻吗洛尔制剂中的应用
CN116056687B (zh)	2020-03-02	2025-10-10	上海奥科达医药科技股份有限公司	含有mtor抑制剂的外用制剂
CN112022798B (zh) *	2020-08-11	2022-04-29	四川大学华西医院	一种速效他克莫司软膏、制备方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH26083A (en) *	1987-11-09	1992-02-06	Sandoz Ltd	11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
KR0159766B1 (ko) *	1989-10-16	1998-12-01	후지사와 토모키치로	양모제 조성물
US5061700A (en) *	1989-11-16	1991-10-29	Gordon Jay Dow	Glyceryl acetate ointment vehicles

1991
- 1991-08-30 ES ES91114598T patent/ES2099112T3/es not_active Expired - Lifetime
- 1991-08-30 AT AT91114598T patent/ATE150304T1/de not_active IP Right Cessation
- 1991-08-30 SG SG1996005797A patent/SG46547A1/en unknown
- 1991-08-30 AU AU83515/91A patent/AU656145B2/en not_active Expired
- 1991-08-30 DE DE69125230T patent/DE69125230T2/de not_active Expired - Lifetime
- 1991-08-30 DK DK91114598.5T patent/DK0474126T3/da active
- 1991-08-30 EP EP91114598A patent/EP0474126B1/de not_active Expired - Lifetime
- 1991-09-02 KR KR1019910015225A patent/KR100194240B1/ko not_active Expired - Lifetime
- 1991-09-02 IE IE308591A patent/IE913085A1/en not_active IP Right Cessation
- 1991-09-03 RU SU5001707/14A patent/RU2079303C1/ru active Protection Beyond IP Right Term
- 1991-09-03 PH PH43041A patent/PH31282A/en unknown
- 1991-09-03 HU HU912846A patent/HUT59002A/hu unknown
- 1991-09-03 ZA ZA916983A patent/ZA916983B/xx unknown
- 1991-09-04 JP JP3224418A patent/JP2526752B2/ja not_active Expired - Lifetime
- 1991-09-04 PT PT98862A patent/PT98862B/pt not_active IP Right Cessation
- 1991-09-04 CA CA002050623A patent/CA2050623C/en not_active Expired - Lifetime
- 1991-09-04 CN CN91108796A patent/CN1069193C/zh not_active Expired - Lifetime
1993
- 1993-05-17 US US08/062,330 patent/US5385907A/en not_active Expired - Lifetime
1995
- 1995-06-22 HU HU95P/P00363P patent/HU211470A9/hu unknown
1997
- 1997-03-21 GR GR970400563T patent/GR3022883T3/el unknown

Also Published As

Publication number	Publication date
CN1059468A (zh)	1992-03-18
CN1069193C (zh)	2001-08-08
ES2099112T3 (es)	1997-05-16
CA2050623C (en)	2002-02-05
HU211470A9 (en)	1995-11-28
DE69125230D1 (de)	1997-04-24
SG46547A1 (en)	1998-02-20
HK1000006A1 (en)	1997-10-03
EP0474126B1 (de)	1997-03-19
RU2079303C1 (ru)	1997-05-20
PH31282A (en)	1998-07-06
AU656145B2 (en)	1995-01-27
ZA916983B (en)	1992-05-27
DE69125230T2 (de)	1997-07-10
KR100194240B1 (ko)	1999-06-15
HUT59002A (en)	1992-04-28
KR920005987A (ko)	1992-04-27
CA2050623A1 (en)	1992-03-05
EP0474126A1 (de)	1992-03-11
JP2526752B2 (ja)	1996-08-21
GR3022883T3 (en)	1997-06-30
AU8351591A (en)	1992-03-12
IE913085A1 (en)	1992-03-11
PT98862A (pt)	1992-08-31
US5385907A (en)	1995-01-31
JPH0517481A (ja)	1993-01-26
PT98862B (pt)	1999-02-26
DK0474126T3 (de)	1997-04-07

Legal Events

Date	Code	Title	Description
1997-10-15	UEP	Publication of translation of european patent specification
2011-11-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
DE69125230D1 (de)	1997-04-24	Tricyclische Verbindungen enthaltende Salben
AU653556B2 (en)	1994-10-06	Suspendible composition and process for preparing the same
DE3777223D1 (de)	1992-04-16	Feste dispersion der substanz fr-900506.
ES2134860T3 (es)	1999-10-16	Preparacion farmaceutica de accion prolongada.
DK0406791T3 (da)	1995-03-27	Vandigt flydende præparat til ekstern anvendelse
ES2068312T3 (es)	1995-04-16	Formulaciones liquidas acuosas.