ATE150448T1 - Ornithine-decarboxylase hemmende cyclische aminooxy-verbindungen - Google Patents

Ornithine-decarboxylase hemmende cyclische aminooxy-verbindungen

Info

Publication number: ATE150448T1
Authority: AT; Austria
Prior art keywords: pct; ornithine decarboxylase; compounds; aminooxy compounds; inhibiting cyclic
Prior art date: 1993-04-13

Application number

AT94913516T

Other languages

English (en)

Inventor

Joerg Frei

Jaroslav Stanek

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-13

Filing date

1994-04-02

Publication date

1997-04-15

1994-04-02 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1997-04-15 Application granted granted Critical

1997-04-15 Publication of ATE150448T1 publication Critical patent/ATE150448T1/de

Links

-1 AMINOOXY COMPOUNDS Chemical class 0.000 title 1
102000052812 Ornithine decarboxylases Human genes 0.000 title 1
108700005126 Ornithine decarboxylases Proteins 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000002993 cycloalkylene group Chemical group 0.000 abstract 1
239000002818 ornithine decarboxylase inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
- C07C239/08—Hydroxylamino compounds or their ethers or esters
- C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Enzymes And Modification Thereof (AREA)

AT94913516T 1993-04-13 1994-04-02 Ornithine-decarboxylase hemmende cyclische aminooxy-verbindungen ATE150448T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH112893		1993-04-13

Publications (1)

Publication Number	Publication Date
ATE150448T1 true ATE150448T1 (de)	1997-04-15

Family

ID=4203148

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94913516T ATE150448T1 (de)	1993-04-13	1994-04-02	Ornithine-decarboxylase hemmende cyclische aminooxy-verbindungen

Country Status (18)

Country	Link
US (1)	US5516806A (de)
EP (1)	EP0644872B1 (de)
JP (1)	JPH07508045A (de)
CN (1)	CN1034929C (de)
AT (1)	ATE150448T1 (de)
AU (1)	AU673736B2 (de)
CA (1)	CA2135782A1 (de)
CZ (1)	CZ7895A3 (de)
DE (1)	DE69402142T2 (de)
DK (1)	DK0644872T3 (de)
ES (1)	ES2100060T3 (de)
GR (1)	GR3023430T3 (de)
HU (1)	HUT70522A (de)
NZ (1)	NZ265252A (de)
PL (1)	PL306764A1 (de)
RU (1)	RU95110887A (de)
SK (1)	SK3695A3 (de)
WO (1)	WO1994024093A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5610195A (en) *	1993-04-13	1997-03-11	Ciba-Geigy Corporation	Ornithine decarboxylase inhibiting branched aminooxy amino alkane derivatives
US6602862B1 (en) *	2000-09-19	2003-08-05	Merz Pharma Gmbh & Co., Kgaa	1-Amino-alkylcyclohexanes as trypanocidal agents
CN100357262C (zh) *	2002-05-10	2007-12-26	中国农业大学	(E)－O－(烃基)－α－氧代环十二酮肟,其制备方法和作为杀真菌剂的用途
US7230002B2 (en)	2004-02-03	2007-06-12	Glenmark Pharmaceuticals Ltd.	Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof
WO2005075426A1 (en) *	2004-02-03	2005-08-18	Glenmark Pharmaceuticals Ltd.	Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof
WO2009073620A2 (en)	2007-11-30	2009-06-11	Newlink Genetics	Ido inhibitors
US20170268066A1 (en) *	2016-03-15	2017-09-21	Chalmers Ventures Ab	Cancer biomarkers
CN109776502B (zh) *	2018-08-29	2021-06-08	湖北工业大学	一种含异吲哚二酮小分子抑制剂
CN118698279B (zh) *	2024-05-31	2025-04-22	江苏科创石化有限公司	一种位阻胺高效复合脱硫溶剂及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3192110A (en) *	1962-04-24	1965-06-29	Colgate Palmolive Co	Therapeutic aryl and thienyl hydroxylamines
US4390534A (en) *	1978-12-29	1983-06-28	Fujisawa Pharmaceutical Co., Ltd.	Cephem and cepham compounds
FR2520194A1 (fr) *	1982-01-28	1983-07-29	Roussel Uclaf	Application, comme facteur de croissance des vegetaux de la 4-nitrophenyl hydroxylamine
US4853467A (en) *	1987-05-19	1989-08-01	Bristol-Myers Company	Nitrogen containing derivatives of epipodophyllotoxin glucosides
EP0369944A1 (de) *	1988-11-18	1990-05-23	Ciba-Geigy Ag	Substituierte Oxadiaminobutane
DE3934208C2 (de) *	1989-10-13	1994-02-17	Kuesters Eduard Maschf	Spulenkörper für die induktive Beheizung von Walzen
EP0495750A3 (en) *	1991-01-14	1992-09-16	Ciba-Geigy Ag	Heterocyclic hydroxylamine
DE4105160A1 (de) *	1991-02-20	1992-08-27	Basf Ag	Imino-substiuierte phenylderivate, ihre herstellung und diese enthaltende fungizide
US5610195A (en) *	1993-04-13	1997-03-11	Ciba-Geigy Corporation	Ornithine decarboxylase inhibiting branched aminooxy amino alkane derivatives

1994
- 1994-04-02 AT AT94913516T patent/ATE150448T1/de not_active IP Right Cessation
- 1994-04-02 CZ CZ9578A patent/CZ7895A3/cs unknown
- 1994-04-02 WO PCT/EP1994/001035 patent/WO1994024093A1/en not_active Ceased
- 1994-04-02 ES ES94913516T patent/ES2100060T3/es not_active Expired - Lifetime
- 1994-04-02 SK SK36-95A patent/SK3695A3/sk unknown
- 1994-04-02 CN CN94190173A patent/CN1034929C/zh not_active Expired - Fee Related
- 1994-04-02 PL PL94306764A patent/PL306764A1/xx unknown
- 1994-04-02 CA CA002135782A patent/CA2135782A1/en not_active Abandoned
- 1994-04-02 DK DK94913516.4T patent/DK0644872T3/da active
- 1994-04-02 JP JP6522689A patent/JPH07508045A/ja active Pending
- 1994-04-02 EP EP94913516A patent/EP0644872B1/de not_active Expired - Lifetime
- 1994-04-02 NZ NZ265252A patent/NZ265252A/en unknown
- 1994-04-02 DE DE69402142T patent/DE69402142T2/de not_active Expired - Fee Related
- 1994-04-02 AU AU65645/94A patent/AU673736B2/en not_active Ceased
- 1994-04-02 US US08/351,337 patent/US5516806A/en not_active Expired - Fee Related
- 1994-04-02 HU HU9403220A patent/HUT70522A/hu unknown
- 1994-04-02 RU RU95110887/04A patent/RU95110887A/ru unknown
1997
- 1997-05-15 GR GR970401079T patent/GR3023430T3/el unknown

Also Published As

Publication number	Publication date
US5516806A (en)	1996-05-14
AU6564594A (en)	1994-11-08
NZ265252A (en)	1996-09-25
ES2100060T3 (es)	1997-06-01
WO1994024093A1 (en)	1994-10-27
CA2135782A1 (en)	1994-10-27
AU673736B2 (en)	1996-11-21
GR3023430T3 (en)	1997-08-29
DE69402142T2 (de)	1997-11-27
CZ7895A3 (en)	1995-10-18
HUT70522A (en)	1995-10-30
SK3695A3 (en)	1995-07-11
DE69402142D1 (de)	1997-04-24
DK0644872T3 (da)	1997-10-06
RU95110887A (ru)	1996-10-27
CN1034929C (zh)	1997-05-21
CN1104411A (zh)	1995-06-28
EP0644872A1 (de)	1995-03-29
JPH07508045A (ja)	1995-09-07
EP0644872B1 (de)	1997-03-19
PL306764A1 (en)	1995-04-18

Legal Events

Date	Code	Title	Description
1998-06-15	UEP	Publication of translation of european patent specification
1999-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
NO975129D0 (no)	1997-11-07	<alfa>- substituerte pyrimidin-thioalkyl og alkyleterforbindelser som inhibitorer av viral revers transkriptase
PL307527A1 (en)	1995-05-29	Crosslinked polymeric ammonium salts
DE69402142D1 (de)	1997-04-24	Ornithine-decarboxylase hemmende cyclische aminooxy-verbindungen
SE8702550D0 (sv)	1987-06-18	Cysteinproteashemmare
ES2088574T3 (es)	1996-08-16	Derivado de anilida.
NO940135L (no)	1994-07-18	Substituerte dialkyltioetere
DK0883405T3 (da)	2004-06-28	Aminoproteaseinhibitorer
DK0678105T3 (da)	1998-08-10	Oligomere, sterisk hindrede polyamintværbindere ogovertræksammensætninger indeholdende disse
MX9801292A (es)	1998-05-31	Derivados de benzoilo.
NZ503586A (en)	2002-03-28	Thioalkyl alpha substituted pyrimidine compounds for treating HIV.
ES2118394T3 (es)	1998-09-16	Procedimiento para la preparacion de derivados de beta-fenilisoserina.
MX9303587A (es)	1994-01-31	Producto para el cuidado de lentes de contacto, para lentes de contacto duros o blandos.
DK0888379T3 (da)	2001-01-29	Forbindelser tilhørende amidinium-familien, farmaceutiske præparater indeholdende disse forbindelser og anvendelsen deraf
ATE134646T1 (de)	1996-03-15	C63-amidderivate von 34-de(acetylglucosaminyl)-34-deoxy-teicoplanine
GR3023429T3 (en)	1997-08-29	Ornithine decarboxylase inhibiting branched aminooxy amino alkane derivatives.
NO304792B1 (no)	1999-02-15	Nye asykliske amidingruppeinneholdende difosfonsyrederivater, anvendelse derav for fremstilling av le gemidler samt legemidler inneholdende slike
ATE112570T1 (de)	1994-10-15	Von dialkylaminoalkyl-26-sulfonylpristinamycin iib abgeleitete salze.
ATE113843T1 (de)	1994-11-15	Verwendung eines prolylendopeptidase-inhibitors zur behandlung von aids.
GB9304632D0 (en)	1993-04-21	Amide derivatives
KR960700053A (ko)	1996-01-19	방사선회복제로서 리루졸의 이용(application of riluzole as a radiorestorer)
GB190300181A (en)	1903-03-12	An Arrangement for Packing Furniture and like Articles.
NZ516133A (en)	2003-08-29	Alpha substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase
MX9802268A (es)	1998-08-30	Nuevos derivados de la substancia pf1022 de ciclodepsipeptido.
IT1263041B (it)	1996-07-24	Derivati di s,s'-bis(carbossammidofenil)-disolfuro ad attivita' cardiovascolare