ATE151436T1 - 2-beta-morpholino-substituierte androstanderivate - Google Patents
2-beta-morpholino-substituierte androstanderivateInfo
- Publication number
- ATE151436T1 ATE151436T1 AT94203468T AT94203468T ATE151436T1 AT E151436 T1 ATE151436 T1 AT E151436T1 AT 94203468 T AT94203468 T AT 94203468T AT 94203468 T AT94203468 T AT 94203468T AT E151436 T1 ATE151436 T1 AT E151436T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- morpholino
- substituted
- derivatives
- androman
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93309663 | 1993-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE151436T1 true ATE151436T1 (de) | 1997-04-15 |
Family
ID=8214625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94203468T ATE151436T1 (de) | 1993-12-02 | 1994-11-29 | 2-beta-morpholino-substituierte androstanderivate |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5593983A (de) |
| JP (1) | JPH07196684A (de) |
| KR (1) | KR950018038A (de) |
| AT (1) | ATE151436T1 (de) |
| AU (1) | AU681714B2 (de) |
| CA (1) | CA2136915A1 (de) |
| CZ (1) | CZ300694A3 (de) |
| DE (1) | DE69402514D1 (de) |
| FI (1) | FI945674A7 (de) |
| HU (1) | HUT69391A (de) |
| NO (1) | NO944626L (de) |
| NZ (1) | NZ270024A (de) |
| PL (1) | PL306065A1 (de) |
| RU (1) | RU94046107A (de) |
| ZA (1) | ZA949226B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6048859A (en) | 1992-06-29 | 2000-04-11 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
| US5719147A (en) * | 1992-06-29 | 1998-02-17 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
| US6787530B1 (en) | 1996-08-23 | 2004-09-07 | Monash University | Use of pregnane-diones as analgesic agents |
| AR031473A1 (es) * | 2000-11-20 | 2003-09-24 | Lundbeck & Co As H | Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide |
| GB2445746A (en) * | 2007-01-17 | 2008-07-23 | Texcontor Ets | Use of carbonated water as a solvent for freeze drying, and method of purification comprising dissolution of material in carbonated water and freeze drying |
| EP4717314A2 (de) | 2011-10-14 | 2026-04-01 | Sage Therapeutics, LLC | 3,3 disubstituierte 19-nor-pregnanverbindungen, zusammensetzungen und verwendungen davon |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| CN117304245A (zh) | 2013-04-17 | 2023-12-29 | 萨奇治疗股份有限公司 | 刺激神经活性的19-去甲类固醇及其使用方法 |
| SMT202100509T1 (it) | 2013-04-17 | 2021-11-12 | Sage Therapeutics Inc | Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia |
| CA2918735C (en) | 2013-07-19 | 2023-08-01 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| CN105579043B (zh) | 2013-08-23 | 2021-09-14 | 萨奇治疗股份有限公司 | 神经活性类固醇、组合物和其用途 |
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| MY190408A (en) | 2014-10-16 | 2022-04-21 | Sage Therapeutics Inc | Compositions and methods for treating cns disorders |
| US20170233433A1 (en) | 2014-10-16 | 2017-08-17 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| WO2016082789A1 (en) | 2014-11-27 | 2016-06-02 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| LT3250210T (lt) | 2015-01-26 | 2021-04-12 | Sage Therapeutics, Inc. | Kompozicijos ir būdai, skirti gydyti cns sutrikimus |
| DK3258939T3 (da) | 2015-02-20 | 2022-12-12 | Sage Therapeutics Inc | Neuroaktive steroider, sammensætninger og anvendelser heraf |
| CA3030420C (en) | 2016-07-11 | 2025-11-18 | Sage Therapeutics, Inc. | C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE |
| WO2018013613A1 (en) | 2016-07-11 | 2018-01-18 | Sage Therapeutics, Inc. | C17, c20, and c21 substituted neuroactive steroids and their methods of use |
| JP7670626B2 (ja) | 2019-05-31 | 2025-04-30 | セージ セラピューティクス， インコーポレイテッド | 神経刺激性ステロイド及びその組成物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL294500A (de) * | 1962-07-09 | |||
| GB1138605A (en) * | 1965-02-19 | 1969-01-01 | Organon Labor Ltd | Improvements in or relating to new 2-ß,16-ß-diamino-androstanes |
| GB1317184A (en) * | 1969-06-20 | 1973-05-16 | Glaxo Lab Ltd | Steroid-containing pharmaceutical preparations |
| US3816624A (en) * | 1970-06-17 | 1974-06-11 | Glaxo Lab Ltd | Anaesthetic steroids |
| GB1376892A (en) * | 1970-11-12 | 1974-12-11 | Glaxo Lab Ltd | 2beta-substituted-3alpha-hydroxysteroids and their esters |
| GB1377608A (en) * | 1970-12-17 | 1974-12-18 | Glaxo Lab Ltd | 3alpha-hydroxy or acyloxy pregnene-21-ethers |
| GB1380248A (en) * | 1970-12-17 | 1975-01-08 | Glaxo Lab Ltd | 3alpha-hydroxy steroids and esters thereof |
| US3983111A (en) * | 1972-05-05 | 1976-09-28 | Glaxo Laboratories Limited | Steroidal anaesthetics of the pregnane and 19-norpregnane series |
| GB1430932A (en) * | 1972-05-05 | 1976-04-07 | Glaxo Lab Ltd | 21-fluoro-pregnanes |
| GB1454749A (en) * | 1972-11-29 | 1976-11-03 | Akzo Nv | 2beta, 16beta-diamino-androstanes and their preparation |
| GB1570394A (en) * | 1976-01-06 | 1980-07-02 | Glaxo Lab Ltd | 11-acyloxy-3-hydroxy steroids |
| GB1581234A (en) * | 1976-04-05 | 1980-12-10 | Glaxo Operations Ltd | 11a - amino - 3a - hydroxysteroids |
| IE53463B1 (en) * | 1981-06-15 | 1988-11-23 | Akzo Nv | Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same |
| GB8708886D0 (en) * | 1987-04-14 | 1987-05-20 | Akzo Nv | 2beta-morpholino-androstane derivatives |
| GB8709565D0 (en) * | 1987-04-23 | 1987-05-28 | Akzo Nv | 2beta,16beta-diaminoandrostanes |
| ZA934972B (en) * | 1992-07-22 | 1994-02-01 | Akzo Nv | 21-Chloro-pregnane derivative |
-
1994
- 1994-11-02 CZ CZ943006A patent/CZ300694A3/cs unknown
- 1994-11-21 ZA ZA949226A patent/ZA949226B/xx unknown
- 1994-11-29 CA CA002136915A patent/CA2136915A1/en not_active Abandoned
- 1994-11-29 AT AT94203468T patent/ATE151436T1/de not_active IP Right Cessation
- 1994-11-29 DE DE69402514T patent/DE69402514D1/de not_active Expired - Lifetime
- 1994-11-30 NZ NZ270024A patent/NZ270024A/en unknown
- 1994-12-01 HU HU9403454A patent/HUT69391A/hu unknown
- 1994-12-01 PL PL94306065A patent/PL306065A1/xx unknown
- 1994-12-01 RU RU94046107/04A patent/RU94046107A/ru unknown
- 1994-12-01 FI FI945674A patent/FI945674A7/fi not_active Application Discontinuation
- 1994-12-01 KR KR1019940032747A patent/KR950018038A/ko not_active Withdrawn
- 1994-12-01 US US08/347,974 patent/US5593983A/en not_active Expired - Fee Related
- 1994-12-01 AU AU79175/94A patent/AU681714B2/en not_active Expired - Fee Related
- 1994-12-01 NO NO944626A patent/NO944626L/no unknown
- 1994-12-02 JP JP6299961A patent/JPH07196684A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PL306065A1 (en) | 1995-06-12 |
| NZ270024A (en) | 1995-10-26 |
| CA2136915A1 (en) | 1995-06-03 |
| AU7917594A (en) | 1995-06-08 |
| ZA949226B (en) | 1995-08-01 |
| RU94046107A (ru) | 1996-09-27 |
| FI945674A0 (fi) | 1994-12-01 |
| HUT69391A (en) | 1995-09-28 |
| KR950018038A (ko) | 1995-07-22 |
| NO944626L (no) | 1995-06-06 |
| FI945674L (fi) | 1995-06-03 |
| JPH07196684A (ja) | 1995-08-01 |
| NO944626D0 (no) | 1994-12-01 |
| HU9403454D0 (en) | 1995-02-28 |
| US5593983A (en) | 1997-01-14 |
| AU681714B2 (en) | 1997-09-04 |
| FI945674A7 (fi) | 1995-06-03 |
| CZ300694A3 (en) | 1996-05-15 |
| DE69402514D1 (de) | 1997-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |