ATE151880T1 - Verfahren und vorrichtung zum nachweis von kontaminationsspuren - Google Patents

Verfahren und vorrichtung zum nachweis von kontaminationsspuren

Info

Publication number
ATE151880T1
ATE151880T1 AT92914471T AT92914471T ATE151880T1 AT E151880 T1 ATE151880 T1 AT E151880T1 AT 92914471 T AT92914471 T AT 92914471T AT 92914471 T AT92914471 T AT 92914471T AT E151880 T1 ATE151880 T1 AT E151880T1
Authority
AT
Austria
Prior art keywords
trace solute
solute
trace
product
contamination
Prior art date
Application number
AT92914471T
Other languages
English (en)
Inventor
Noubar B Afeyan
Original Assignee
Perseptive Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perseptive Biosystems Inc filed Critical Perseptive Biosystems Inc
Application granted granted Critical
Publication of ATE151880T1 publication Critical patent/ATE151880T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/14—Preparation by elimination of some components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N2030/062—Preparation extracting sample from raw material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G01N2030/085—Preparation using an enricher using absorbing precolumn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/14—Preparation by elimination of some components
    • G01N2030/143—Preparation by elimination of some components selective absorption
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8872—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample impurities

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT92914471T 1991-06-26 1992-06-15 Verfahren und vorrichtung zum nachweis von kontaminationsspuren ATE151880T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72119291A 1991-06-26 1991-06-26

Publications (1)

Publication Number Publication Date
ATE151880T1 true ATE151880T1 (de) 1997-05-15

Family

ID=24896927

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92914471T ATE151880T1 (de) 1991-06-26 1992-06-15 Verfahren und vorrichtung zum nachweis von kontaminationsspuren

Country Status (8)

Country Link
US (1) US5306426A (de)
EP (1) EP0591407B1 (de)
JP (1) JP3431142B2 (de)
AT (1) ATE151880T1 (de)
AU (1) AU660480B2 (de)
CA (1) CA2111695A1 (de)
DE (1) DE69219125T2 (de)
WO (1) WO1993000584A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5492834A (en) * 1993-07-09 1996-02-20 Beckman Instruments, Inc. Method of sample preparation for urine protein analysis with capillary electrophoresis
AU5438796A (en) 1995-04-06 1996-10-23 Arqule, Inc. Method for rapid purification, analysis and characterization of collections of chemical compounds
US5670054A (en) * 1996-04-04 1997-09-23 Warner Lambert Company Method and system for identification, purification, and quantitation of reaction components
DE19914358C2 (de) * 1999-03-30 2001-05-17 Agilent Technologies Inc Vorrichtung und Verfahren zur Bereitstellung von Volumenströmen von Flüssigkeiten in Kapillaren
US6106710A (en) * 1999-09-10 2000-08-22 Agilent Technologies, Inc. Fraction collection delay calibration for liquid chromatography
US6767467B2 (en) * 2000-07-06 2004-07-27 Agilent Technologies, Inc. Fraction collection delay calibration for liquid chromatography
US6558624B1 (en) * 2000-07-25 2003-05-06 General Electric Company Method and analytical system for rapid screening of combinatorial libraries
EP1461620A4 (de) * 2001-12-05 2005-02-02 Large Scale Biology Corp Flexibles verfahren und gerät zur produktion und reinigung mehrerer proteine mit hohem durchsatz
US7473367B2 (en) * 2002-06-26 2009-01-06 Dionex Corporation Monolithic column
US20050061745A1 (en) * 2002-06-26 2005-03-24 Teledyne Isco, Inc. Separation system, components of a separation system and methods of making and using them
US6749749B2 (en) * 2002-06-26 2004-06-15 Isco, Inc. Separation system, components of a separation system and methods of making and using them
WO2004080576A1 (de) * 2003-03-12 2004-09-23 Ksb Aktiengesellschaft Armatur für anlagen mit drucktauschern
US7332087B2 (en) * 2003-11-26 2008-02-19 Waters Investments Limited Flow sensing apparatus used to monitor/provide feedback to a split flow pumping system
US7186336B2 (en) * 2003-11-26 2007-03-06 Waters Investments Limited Flow sensing apparatus
US7204264B2 (en) * 2004-04-21 2007-04-17 Waters Investments Ltd. High pressure capillary micro-fluidic valve device and a method of fabricating same
US8877051B2 (en) * 2006-07-21 2014-11-04 Waters Technologies Corporation Time delay for sample collection in chromatography systems
KR20130083490A (ko) * 2007-12-05 2013-07-22 올테크 어소시에이츠, 인크. 시료를 분석하고 시료 분획을 수집하기 위한 방법 및 장치
SG171929A1 (en) 2008-12-04 2011-07-28 Alltech Associates Inc Methods and apparatus for moving aliquot samples of fluid
KR20110104004A (ko) 2008-12-10 2011-09-21 올테크 어소시에이츠, 인크. 크로마토그래피 시스템용 기계 판독형 태그 리더, 크로마토그래피 시스템의 분별 수집 시스템, 및 크로마토그래피 시스템
US8314934B2 (en) 2009-09-01 2012-11-20 Alltech Associates, Inc. Methods and apparatus for analyzing samples and collecting sample fractions
DE102016003843B3 (de) * 2016-03-30 2017-03-09 Jörg-Helge Hein Vorrichtung und Verfahren zum Bestimmen einer Konzentration zumindest eines Stoffes in einem flüssigen Medium
CN107632057B (zh) * 2017-10-31 2024-06-21 湖南三码头食品有限公司 食品快速连续检测装置
US12210028B2 (en) 2019-05-03 2025-01-28 Gen-Probe Incorporated Receptacle delivery system

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2036525B2 (de) * 1970-07-23 1974-06-20 Boehringer Mannheim Gmbh Verfahren und Vorrichtung zur chromatographischen Auftrennung von Mehrstoffgemischen
US3701609A (en) * 1971-05-13 1972-10-31 David G Bailey Apparatus for automatically adding preselected patterns of eluent solutions to a chromatographic column and monitoring and collecting eluted fractions
US4070284A (en) * 1973-08-20 1978-01-24 Hitachi, Ltd. Liquid chromatography and apparatus for the same
US4003892A (en) * 1975-04-17 1977-01-18 Serva-Entwicklungslabor V. Grothe & Co. Method of separating thionine and its N-methyl derivatives from each other
US4229971A (en) * 1975-04-28 1980-10-28 Phillips Petroleum Company Liquid sampling system
US4271697A (en) * 1979-10-17 1981-06-09 Phillips Petroleum Company Chromatographic analysis
US4454043A (en) * 1980-11-17 1984-06-12 Monsanto Company Column switching procedure
US4500432A (en) * 1981-07-13 1985-02-19 Hewlett-Packard Company Automated sample concentrator for trace components
FR2527934A1 (fr) * 1982-06-03 1983-12-09 Elf Aquitaine Procede de fractionnement de melanges par chromatographie d'elution avec fluide en etat supercritique et installation pour sa mise en oeuvre
JPS60219554A (ja) * 1984-04-16 1985-11-02 Yokogawa Hokushin Electric Corp 多量成分中の微量成分を測定する方法およびその装置
US4597943A (en) * 1984-11-29 1986-07-01 Morinaga & Co., Ltd. Apparatus for analyzing solid sample with supercritical fluid
US4935145A (en) * 1985-01-25 1990-06-19 The Dow Chemical Company On-line coupled liquid and gas chromatography system
US4673733A (en) * 1985-04-11 1987-06-16 Sudhish Chandra Treatment of biological and pharmaceutical products adsorbed on a solid phase with virus and pyrogen inactivating agents
US4631129A (en) * 1985-10-04 1986-12-23 Suomen Sokeri Oy Production of pure sugars and lignosulfonates from sulfite spent liquor
JPS62138753A (ja) * 1985-12-12 1987-06-22 Hitachi Ltd 液体クロマトグラフイによる分画・分取方法および装置
US4699718A (en) * 1986-01-21 1987-10-13 Millipore Corporation Ion chromatography method and apparatus
FR2597980B1 (fr) * 1986-04-25 1990-11-16 Rhone Poulenc Rech Procede et installation d'analyse en ligne d'un produit liquide par chromatographie en phase liquide
US4826603A (en) * 1986-09-09 1989-05-02 United States Of America As Represented By The Secretary Of The Air Force Hydrocarbon group-type analyzer system
EP0297149A1 (de) * 1987-06-27 1989-01-04 Hewlett-Packard GmbH Verfahren und Vorrichtung zur Trennung von Substanzgemischen
US4872992A (en) * 1987-12-09 1989-10-10 Atlantic Richfield Company Method and apparatus for analyzing diluted and undiluted fluid samples
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
IL87004A (en) * 1988-07-06 1992-08-18 Technion Res & Dev Foundation Method and apparatus for bioaffinity separation
US5019270A (en) * 1989-07-06 1991-05-28 Perseptive Biosystems, Inc. Perfusive chromatography

Also Published As

Publication number Publication date
JPH06510600A (ja) 1994-11-24
DE69219125D1 (de) 1997-05-22
AU2238892A (en) 1993-01-25
AU660480B2 (en) 1995-06-29
CA2111695A1 (en) 1993-01-07
WO1993000584A1 (en) 1993-01-07
EP0591407B1 (de) 1997-04-16
DE69219125T2 (de) 1997-07-24
US5306426A (en) 1994-04-26
EP0591407A1 (de) 1994-04-13
JP3431142B2 (ja) 2003-07-28

Similar Documents

Publication Publication Date Title
DE69219125D1 (de) Verfahren und vorrichtung zum nachweis von kontaminationsspuren
DE60039179D1 (de) Verfahren und vorrichtung zur messung von flüssen men
DE3750058D1 (de) Vorrichtung zum Abtrennen von Gasblasen aus Flüssigkeiten.
DE3780282D1 (de) Verfahren zum messen von massendurchflussraten und vorrichtung dafuer.
ATE320069T1 (de) Verfahren und vorrichtung zur trennung der ionen von metallischen elementen in wässriger lösung
CH495291A (de) Verfahren und Vorrichtung zur Reinigung von Wasser aus einem Grundwasser-Brunnen
DE3877229D1 (de) Verfahren zum entfernen von nox aus fluidstroemen.
DE4392040D2 (de) Vorrichtung zum Abtrennen von Flüssigkeit aus Feststoff-Flüssigkeitsmischungen
DE69206136D1 (de) Vorrichtung und Verfahren zur Trennung von Flüssigkeitsproben.
DE3280399D1 (de) Verfahren und vorrichtung zum nachweis von neutrinos und anwendungen des neutrinodetektors.
CH540711A (de) Verfahren und Vorrichtung zum Abscheiden von Verunreinigungen aus strömenden Gasen
DE69008818D1 (de) Vorrichtung und verfahren zur kontinuierlichen entfernung von sauerstoff aus flüssigkeitsströmen.
AT365081B (de) Verfahren und vorrichtung zum kontinuierlichen schwerkrafttrennen von gemischen aus fluessigkeiten und feststoffen
DE69106099D1 (de) Verfahren und Vorrichtung zur Lieferung von einem Gas an einen sehr empfindlichen Analysator.
AT386400B (de) Verfahren und vorrichtung zum abtrennen von feststoffen aus fluessigkeiten
AT378361B (de) Vorrichtung zum ausscheiden von feststoffen aus fluessigkeiten
DE3860326D1 (de) Vorrichtung zum abscheiden von feststoffen aus fluessigkeiten in zahnaerztlichen einrichtungen.
DE58901256D1 (de) Vorrichtung zum aufbereiten von proben aus einem schuettgutstrom.
FR2718057B1 (fr) Procédé et appareil pour la séparation isotopique du bore dans des solutions aqueuses d'acide borique.
FI810787A7 (fi) Menetelmä ja laite kantajanesteen sisältämien tai siihen lisättyjen, liuenneiden tai liukenevien aineidemuuttamiseksi ja erottamiseksi.
EP0868932A3 (de) Verfahren zur Trennung von Bestandteilen einer flüssigen Probe und Vorrichtung
DE69510780D1 (de) Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographie
ATE534031T1 (de) Verfahren und vorrichtung für die chemische regenerierung mit verschiebung
DE69012734D1 (de) Verfahren zum Eluieren von adsorbiertem Gold aus Kohlenstoff.
DE3580656D1 (de) Verfahren und vorrichtung zum feststellen von phasenveraenderungen.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties