ATE152143T1 - Polyethylenglykol oder polypropylenglykol enthaltend polymer - Google Patents

Polyethylenglykol oder polypropylenglykol enthaltend polymer

Info

Publication number: ATE152143T1
Authority: AT; Austria
Prior art keywords: glycol; polymer; containing polymer; peptides; proteins
Prior art date: 1992-02-13

Application number

AT93903869T

Other languages

English (en)

Inventor

Morten Peter Meldal

Original Assignee

Carlsberg As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-13

Filing date

1993-02-12

Publication date

1997-05-15

1993-02-12 Application filed by Carlsberg As filed Critical Carlsberg As

1997-05-15 Application granted granted Critical

1997-05-15 Publication of ATE152143T1 publication Critical patent/ATE152143T1/de

Links

229920000642 polymer Polymers 0.000 title abstract 4
239000002202 Polyethylene glycol Substances 0.000 title 1
229920001223 polyethylene glycol Polymers 0.000 title 1
229920001451 polypropylene glycol Polymers 0.000 title 1
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 4
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 2
239000005977 Ethylene Substances 0.000 abstract 2
-1 hydroxy, carboxyl Chemical group 0.000 abstract 2
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 abstract 2
125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
239000007787 solid Substances 0.000 abstract 2
239000000758 substrate Substances 0.000 abstract 2
HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 abstract 1
108091034117 Oligonucleotide Proteins 0.000 abstract 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
150000001720 carbohydrates Chemical class 0.000 abstract 1
238000007334 copolymerization reaction Methods 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000000524 functional group Chemical group 0.000 abstract 1
150000002825 nitriles Chemical class 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
229920001542 oligosaccharide Polymers 0.000 abstract 1
150000002482 oligosaccharides Chemical class 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
239000011347 resin Substances 0.000 abstract 1
229920005989 resin Polymers 0.000 abstract 1
125000006850 spacer group Chemical group 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/062—Polyethers

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
Biophysics (AREA)
Polymers & Plastics (AREA)
Peptides Or Proteins (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicinal Preparation (AREA)
Polyethers (AREA)
Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Graft Or Block Polymers (AREA)
Polyesters Or Polycarbonates (AREA)
Materials For Medical Uses (AREA)

AT93903869T 1992-02-13 1993-02-12 Polyethylenglykol oder polypropylenglykol enthaltend polymer ATE152143T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US83527792A	1992-02-13	1992-02-13

Publications (1)

Publication Number	Publication Date
ATE152143T1 true ATE152143T1 (de)	1997-05-15

Family

ID=25269099

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93903869T ATE152143T1 (de)	1992-02-13	1993-02-12	Polyethylenglykol oder polypropylenglykol enthaltend polymer

Country Status (11)

Country	Link
US (1)	US5352756A (de)
EP (1)	EP0625996B1 (de)
JP (1)	JPH07503744A (de)
AT (1)	ATE152143T1 (de)
AU (1)	AU660534B2 (de)
BR (1)	BR9305894A (de)
CA (1)	CA2129442C (de)
DE (1)	DE69310148T2 (de)
DK (1)	DK0625996T3 (de)
ES (1)	ES2101300T3 (de)
WO (1)	WO1993016118A1 (de)

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US5656707A (en) *	1995-06-16	1997-08-12	Regents Of The University Of Minnesota	Highly cross-linked polymeric supports
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DE19741356C2 (de) *	1997-09-19	2001-02-15	Cognis Deutschland Gmbh	Verwendung von Glucoprotaminen
CZ296517B6 (cs)	1998-09-28	2006-04-12	Carlsberg A/S	Makromonomery na bázi polyethylenglykolu, chemicky inertní polymery pripravené z techto makromonomeru a pouzití techto polymeru pro organické syntézya enzymatické reakce
US6722054B2 (en)	1998-11-12	2004-04-20	Atrix Laboratories, Inc.	Process and delivery container for lyophilizing active agent
US6907679B2 (en) *	1998-11-12	2005-06-21	Qlt Usa, Inc.	Method for lyophilizing an active agent
GB9926435D0 (en) *	1999-11-08	2000-01-12	Polymer Lab Ltd	Method
US6566144B1 (en) *	2000-03-27	2003-05-20	Atrix Laboratories	Cover plate for use in lyophilization
MXPA03000310A (es) *	2000-07-12	2004-12-13	Gryphon Therapeutics Inc	Quimiocinas sinteticas bioactivas, modificadas con polimeros y metodos para su elaboracion y uso.
US7118737B2 (en) *	2000-09-08	2006-10-10	Amylin Pharmaceuticals, Inc.	Polymer-modified synthetic proteins
US20030191291A1 (en) *	2000-09-08	2003-10-09	Kochendoerfer Gerd G.	Synthetic erythropoiesis stimulating proteins
AU2002218089A1 (en) *	2000-11-20	2002-05-27	Matrix Innovation Inc.	Amphiphile solid support for peptide synthesis, bioorganic and organic chemistry
US6979530B2 (en) *	2001-05-21	2005-12-27	Applera Corporation	Peptide conjugates and fluorescence detection methods for intracellular caspase assay
US20040077835A1 (en) *	2001-07-12	2004-04-22	Robin Offord	Chemokine receptor modulators, production and use
US20030138880A1 (en) *	2001-08-24	2003-07-24	University Of British Columbia	Solid-phase synthesis of oligosaccharides and glycopeptides using glycosynthases
WO2003031489A2 (en) *	2001-10-12	2003-04-17	Carlsberg A/S	Matrix for solid-phase organic synthesis
US8034900B2 (en) *	2002-12-30	2011-10-11	Amylin Pharmaceuticals, Inc.	Water-soluble thioester and selenoester compounds and methods for making and using the same
EP1687343B1 (de)	2003-08-04	2014-07-23	Matrix Innovation Inc.	Neue polyetherbasierte monomere und hochvernetzte amphiphile harze
EP1868652A2 (de)	2005-04-05	2007-12-26	Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A.	Verfahren zur abschirmung von funktionalen stellen oder epitopen auf proteinen
US7985783B2 (en)	2006-09-21	2011-07-26	The Regents Of The University Of California	Aldehyde tags, uses thereof in site-specific protein modification
AU2012278944B2 (en)	2011-07-05	2015-09-17	Bioasis Technologies Inc.	p97-antibody conjugates and methods of use
WO2014022515A1 (en)	2012-07-31	2014-02-06	Bioasis Technologies, Inc.	Dephosphorylated lysosomal storage disease proteins and methods of use thereof
CN104884056A (zh)	2012-11-12	2015-09-02	雷德伍德生物科技股份有限公司	用于制备缀合物的化合物和方法
WO2014078733A1 (en)	2012-11-16	2014-05-22	The Regents Of The University Of California	Pictet-spengler ligation for protein chemical modification
US9310374B2 (en)	2012-11-16	2016-04-12	Redwood Bioscience, Inc.	Hydrazinyl-indole compounds and methods for producing a conjugate
NZ711373A (en)	2013-03-13	2020-07-31	Bioasis Technologies Inc	Fragments of p97 and uses thereof
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CN115504924A (zh)	2013-11-27	2022-12-23	雷德伍德生物科技股份有限公司	肼基-吡咯并化合物及用于生成缀合物的方法
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WO2019133399A1 (en)	2017-12-26	2019-07-04	Becton, Dickinson And Company	Deep ultraviolet-excitable water-solvated polymeric dyes
CN112384573A (zh)	2018-03-30	2021-02-19	贝克顿·迪金森公司	含侧基发色团的水溶性聚合染料
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1993
- 1993-02-12 EP EP93903869A patent/EP0625996B1/de not_active Expired - Lifetime
- 1993-02-12 DE DE69310148T patent/DE69310148T2/de not_active Expired - Lifetime
- 1993-02-12 AU AU34934/93A patent/AU660534B2/en not_active Ceased
- 1993-02-12 AT AT93903869T patent/ATE152143T1/de not_active IP Right Cessation
- 1993-02-12 ES ES93903869T patent/ES2101300T3/es not_active Expired - Lifetime
- 1993-02-12 DK DK93903869.1T patent/DK0625996T3/da active
- 1993-02-12 WO PCT/DK1993/000051 patent/WO1993016118A1/en not_active Ceased
- 1993-02-12 CA CA002129442A patent/CA2129442C/en not_active Expired - Fee Related
- 1993-02-12 BR BR9305894A patent/BR9305894A/pt not_active Application Discontinuation
- 1993-02-12 JP JP5513684A patent/JPH07503744A/ja active Pending
- 1993-06-11 US US08/075,758 patent/US5352756A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0625996B1 (de)	1997-04-23
BR9305894A (pt)	1997-08-19
DE69310148T2 (de)	1997-07-31
AU660534B2 (en)	1995-06-29
ES2101300T3 (es)	1997-07-01
DE69310148D1 (de)	1997-05-28
US5352756A (en)	1994-10-04
AU3493493A (en)	1993-09-03
JPH07503744A (ja)	1995-04-20
CA2129442A1 (en)	1993-08-14
DK0625996T3 (da)	1997-06-02
CA2129442C (en)	2003-05-27
WO1993016118A1 (en)	1993-08-19
EP0625996A1 (de)	1994-11-30

Legal Events

Date	Code	Title	Description
1997-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69310148D1 (de)	1997-05-28	Polyethylenglykol oder polypropylenglykol enthaltend polymer
AU556670B2 (en)	1986-11-13	Absorbent panel for absorbent products
ATE352801T1 (de)	2007-02-15	Ethylen-vinylacetat-kohlenmonoxyd-terpolymer enthaltendes bildaufzeichnungsmedium
MX169277B (es)	1993-06-28	Peliculas termoplasticas para usarse en aplicaciones de alargamiento/adherencia
BR8501408A (pt)	1985-11-26	Composicao de revestimento liquida
KR960703956A (ko)	1996-08-31	아크릴릭-포화 고무 하이브리드 감압 접착제
KR880012719A (ko)	1988-11-28	점착성 아크릴계 감압성 접착제
EP0819746A3 (de)	2000-08-23	Ein vernetzbares druckempfindliches Klebmittel im Plattenform
DE69302107D1 (de)	1996-05-15	Durch Wasser inaktivierbarer, druckempfindlicher Klebstoff
DK42687D0 (da)	1987-01-27	Polymeranalog-modificerede polymerisater
KR910019769A (ko)	1991-12-19	고무제품에 사용하는 장식용 필름
TW343989B (en)	1998-11-01	Coating composition for a plastic film
ATE77631T1 (de)	1992-07-15	Strahlenhaertbare harzzusammensetzung.
KR950005868A (ko)	1995-03-20	생분해성 수지 조성물 및 방오 도료 조성물
ES2053870T3 (es)	1994-08-01	Substancias de carga.
AU3309989A (en)	1989-10-19	Crosslinked polymer compositions, a process for their production and moulded articles obtained
EP0335410A3 (de)	1991-03-13	Wasserquellfähige Harzzusammensetzung
JPS5614565A (en)	1981-02-12	Self-adhesive for surface protecting film
ATE224434T1 (de)	2002-10-15	Druckempfindliche klebmittelzusammensetzung enthaltend styrol-maleinsäure-copolymerisate
KR870006132A (ko)	1987-07-09	고무 조성물
EP0389429A3 (de)	1991-11-27	Azoverbindungen mit einer sterisch gehinderten Aminogruppe geringer Basizität
EP0801117A3 (de)	1998-04-15	Anwuchsverhindernde Harzzusammensetzung
EP0458481A3 (de)	1991-12-18	Polymerfilm
KR920018187A (ko)	1992-10-21	변성 폴리올레핀계 접착성 수지조성물
ATE268350T1 (de)	2004-06-15	Klebstoffzusammensetzung für methacrylat- copolymere