ATE152631T1 - Vorvaskularisierte polymerimplantate für organtransplantation - Google Patents

Vorvaskularisierte polymerimplantate für organtransplantation

Info

Publication number
ATE152631T1
ATE152631T1 AT92924131T AT92924131T ATE152631T1 AT E152631 T1 ATE152631 T1 AT E152631T1 AT 92924131 T AT92924131 T AT 92924131T AT 92924131 T AT92924131 T AT 92924131T AT E152631 T1 ATE152631 T1 AT E152631T1
Authority
AT
Austria
Prior art keywords
cells
vascular
matrix
connective tissue
patient
Prior art date
Application number
AT92924131T
Other languages
English (en)
Inventor
James E Stein
James C Gilbert
Donald E Ingber
Robert S Langer
Joseph P Vacanti
Original Assignee
Massachusetts Inst Technology
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Childrens Medical Center filed Critical Massachusetts Inst Technology
Application granted granted Critical
Publication of ATE152631T1 publication Critical patent/ATE152631T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
AT92924131T 1991-10-30 1992-10-28 Vorvaskularisierte polymerimplantate für organtransplantation ATE152631T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78502191A 1991-10-30 1991-10-30

Publications (1)

Publication Number Publication Date
ATE152631T1 true ATE152631T1 (de) 1997-05-15

Family

ID=25134239

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92924131T ATE152631T1 (de) 1991-10-30 1992-10-28 Vorvaskularisierte polymerimplantate für organtransplantation

Country Status (6)

Country Link
EP (1) EP0610423B1 (de)
JP (2) JP3524919B2 (de)
AT (1) ATE152631T1 (de)
CA (1) CA2121040A1 (de)
DE (1) DE69219613T2 (de)
WO (1) WO1993008850A1 (de)

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DE69431295T2 (de) 1993-04-21 2003-05-15 Institut Pasteur, Paris Biokompatibles implantat zur in vivo expression und sekretion von therapeutischer verbindung
FR2708202B1 (fr) * 1993-07-26 1996-03-29 Pasteur Institut Implant biocompatible pour l'expression chez l'homme ou chez l'animal de substances déterminées.
WO1994025079A1 (en) * 1993-04-23 1994-11-10 Massachusetts Institute Of Technology Porous biodegradable polymeric materials for cell transplantation
WO1995001810A1 (en) * 1993-07-07 1995-01-19 Smith & Nephew Plc Implantable prosthesis, kit and device for manufacturing the same
AU678843B2 (en) * 1993-08-10 1997-06-12 W.L. Gore & Associates, Inc. Cell encapsulating device
US6176874B1 (en) * 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US5549675A (en) * 1994-01-11 1996-08-27 Baxter International, Inc. Method for implanting tissue in a host
WO1995024929A2 (en) 1994-03-15 1995-09-21 Brown University Research Foundation Polymeric gene delivery system
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5648088A (en) 1995-03-06 1997-07-15 Ethicon, Inc. Blends of absorbable polyoxaesters containing amines and/or amide groups
US6123727A (en) 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
WO1997010807A1 (en) * 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
EP0771849B1 (de) 1995-11-06 2004-01-28 Ethicon, Inc. Polymermischungen die Polyoxaestern und Lactonpolymeren enthalten
WO1998021312A1 (en) * 1996-11-08 1998-05-22 Rpms Technology Limited Human hepatocytes in three-dimensional support systems
US6316522B1 (en) 1997-08-18 2001-11-13 Scimed Life Systems, Inc. Bioresorbable hydrogel compositions for implantable prostheses
US6129757A (en) 1998-05-18 2000-10-10 Scimed Life Systems Implantable members for receiving therapeutically useful compositions
WO2000021470A1 (en) 1998-10-12 2000-04-20 Therics, Inc. Composites for tissue regeneration and methods of manufacture thereof
NZ524234A (en) * 2000-08-21 2004-10-29 Bernard O Brien Inst Of Micros Vascularised tissue graft
US7998735B2 (en) 2000-08-21 2011-08-16 Victorian Tissue Engineering Centre Pty. Ltd. Vascularized tissue graft
KR20010044624A (ko) * 2001-03-12 2001-06-05 정재호 연골조직공학을 위한 연골지지체의 제조방법 및 이연골지지체를 사용하여 제조한 인공연골
US7034037B2 (en) 2001-06-29 2006-04-25 Ethicon, Inc. Compositions and medical devices utilizing bioabsorbable polymeric waxes and rapamycin
US6967234B2 (en) 2002-12-18 2005-11-22 Ethicon, Inc. Alkyd-lactone copolymers for medical applications
US7030127B2 (en) 2001-06-29 2006-04-18 Ethicon, Inc. Composition and medical devices utilizing bioabsorbable polymeric waxes
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US7005136B2 (en) 2002-03-29 2006-02-28 Ethicon, Inc. Bone replacement materials utilizing bioabsorbable liquid polymers
US7368125B2 (en) 2002-06-05 2008-05-06 Ethicon, Inc. Amphiphilic polymers for medical applications
US7026374B2 (en) 2002-06-25 2006-04-11 Aruna Nathan Injectable microdispersions for medical applications
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US6872799B2 (en) 2002-12-18 2005-03-29 Ethicon, Inc. Functionalized polymers for medical applications
US6866860B2 (en) 2002-12-19 2005-03-15 Ethicon, Inc. Cationic alkyd polyesters for medical applications
EP2335650B1 (de) 2003-12-11 2012-10-03 Isto Technologies Inc. Teilchenförmiges Knorpelsystem
JP4422719B2 (ja) * 2004-04-12 2010-02-24 大日本印刷株式会社 人工組織およびその製造方法
US8512730B2 (en) 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
AU2006252402B2 (en) * 2005-06-02 2010-11-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Prevascularized devices and related methods
WO2007025290A2 (en) 2005-08-26 2007-03-01 Isto Technologies, Inc. Implants and methods for repair, replacement and treatment of joint disease
SI1948259T1 (sl) 2005-10-26 2017-07-31 Genesis Technologies Limited Acelularni bioabsorbljivi tkivni regeneracijski matriksi, proizvedeni z inkubiranjem acelularnih proizvodov krvi
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
EP2134297B1 (de) 2007-04-12 2017-03-08 Zimmer, Inc. Vorrichtung zur gewebereparatur
DK2470228T3 (en) * 2009-08-28 2018-01-02 Sernova Corp METHODS AND DEVICES FOR CELLULAR TRANSPLANTATION
WO2011098367A2 (en) 2010-02-12 2011-08-18 Universität Zürich Method for in-vitro production of tissue engineered auto- and allografts suitable for guarded cryopreservation
US9877822B2 (en) 2012-04-24 2018-01-30 Biostage, Inc. Engineered tissue scaffolds and supports therefor
US10245306B2 (en) 2012-11-16 2019-04-02 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
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Also Published As

Publication number Publication date
EP0610423B1 (de) 1997-05-07
CA2121040A1 (en) 1993-05-13
DE69219613D1 (de) 1997-06-12
JP3524919B2 (ja) 2004-05-10
EP0610423A1 (de) 1994-08-17
WO1993008850A1 (en) 1993-05-13
JPH07508663A (ja) 1995-09-28
DE69219613T2 (de) 1997-11-27
JP2002200162A (ja) 2002-07-16

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UEP Publication of translation of european patent specification