ATE154513T1 - Augenarzneimittel enthaltend timolol hemihydrat - Google Patents

Augenarzneimittel enthaltend timolol hemihydrat

Info

Publication number: ATE154513T1
Authority: AT; Austria
Prior art keywords: compsn; adjusters; pref; contg; adjuvants
Prior art date: 1992-07-08

Application number

AT92850297T

Other languages

English (en)

Inventor

Markku Peraelampi

Kari Lehmussaari

Olli Oksala

Esko Pohjala

Timo Reunamaeki

Jarkko Ruohonen

Original Assignee

Leiras Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-08

Filing date

1992-12-16

Publication date

1997-07-15

1992-12-16 Application filed by Leiras Oy filed Critical Leiras Oy

1997-07-15 Application granted granted Critical

1997-07-15 Publication of ATE154513T1 publication Critical patent/ATE154513T1/de

Links

TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 title 1
229960000454 timolol hemihydrate Drugs 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 2
239000002671 adjuvant Substances 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 1
230000002708 enhancing effect Effects 0.000 abstract 1
239000002674 ointment Substances 0.000 abstract 1
239000003755 preservative agent Substances 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Ophthalmology & Optometry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT92850297T 1992-07-08 1992-12-16 Augenarzneimittel enthaltend timolol hemihydrat ATE154513T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US91066592A	1992-07-08	1992-07-08

Publications (1)

Publication Number	Publication Date
ATE154513T1 true ATE154513T1 (de)	1997-07-15

Family

ID=25429138

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92850297T ATE154513T1 (de)	1992-07-08	1992-12-16	Augenarzneimittel enthaltend timolol hemihydrat

Country Status (21)

Country	Link
EP (1)	EP0577913B1 (de)
JP (1)	JP3094233B2 (de)
KR (1)	KR100278851B1 (de)
AT (1)	ATE154513T1 (de)
AU (1)	AU678972B2 (de)
BR (1)	BR9306800A (de)
CA (1)	CA2139781C (de)
CZ (1)	CZ282168B6 (de)
DE (1)	DE69220484T2 (de)
DK (1)	DK0577913T3 (de)
EE (1)	EE03078B1 (de)
ES (1)	ES2106852T3 (de)
FI (1)	FI112321B (de)
GR (1)	GR3024648T3 (de)
HK (1)	HK1007503A1 (de)
HU (1)	HU221618B1 (de)
NO (1)	NO306535B1 (de)
NZ (1)	NZ253164A (de)
PL (1)	PL172503B1 (de)
SG (1)	SG49770A1 (de)
WO (1)	WO1994001115A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2317650T3 (es)	1996-10-28	2009-04-16	Senju Pharmaceutical Co., Ltd.	Farmacos para mejorar trastornos circulatorios oculares.
IT1298758B1 (it) *	1998-03-19	2000-02-02	Angelini Ricerche Spa	Soluzione umettante e lubrificante per uso oftalmico
UA72207C2 (uk) *	1998-04-07	2005-02-15	Брістол- Майєрс Сквібб Фарма Компані	Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення
WO2004098592A1 (ja) *	2003-05-06	2004-11-18	Senju Pharmaceutical Co. Ltd.	オキサゾリジノン誘導体含有組成物
US7862552B2 (en)	2005-05-09	2011-01-04	Boston Scientific Scimed, Inc.	Medical devices for treating urological and uterine conditions
JP2014024794A (ja) *	2012-07-27	2014-02-06	Nippon Tenganyaku Kenkyusho:Kk	チモロールまたはその薬学的に許容される塩を含有する水性組成物およびその光安定化方法
GR1008483B (el) *	2013-12-23	2015-05-12	Rafarm Α.Ε.Β.Ε.,	Οφθαλμικη φαρμακευτικη συνθεση και μεθοδος για την παρασκευη αυτης

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4195085A (en)	1975-09-26	1980-03-25	Merck & Co., Inc.	Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate
NZ196227A (en) *	1980-02-19	1984-09-28	Merck & Co Inc	1,2,5-thiadiazole derivative and ophthalmic compositions
US4752478A (en) *	1984-12-17	1988-06-21	Merck & Co., Inc.	Transdermal system for timolol
GB8822285D0 (en) *	1988-09-22	1988-10-26	Ddsa Pharmaceuticals Ltd	Opthalmic preparations
FI82240C (fi)	1988-10-20	1991-02-11	Huhtamaeki Oy	Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

1992
- 1992-12-16 DK DK92850297.0T patent/DK0577913T3/da active
- 1992-12-16 AT AT92850297T patent/ATE154513T1/de not_active IP Right Cessation
- 1992-12-16 SG SG1996005344A patent/SG49770A1/en unknown
- 1992-12-16 ES ES92850297T patent/ES2106852T3/es not_active Expired - Lifetime
- 1992-12-16 DE DE69220484T patent/DE69220484T2/de not_active Expired - Lifetime
- 1992-12-16 EP EP92850297A patent/EP0577913B1/de not_active Expired - Lifetime
1993
- 1993-06-23 WO PCT/FI1993/000269 patent/WO1994001115A1/en not_active Ceased
- 1993-06-23 KR KR1019950700060A patent/KR100278851B1/ko not_active Expired - Fee Related
- 1993-06-23 CA CA002139781A patent/CA2139781C/en not_active Expired - Fee Related
- 1993-06-23 AU AU43296/93A patent/AU678972B2/en not_active Ceased
- 1993-06-23 NZ NZ253164A patent/NZ253164A/en unknown
- 1993-06-23 BR BR9306800A patent/BR9306800A/pt not_active Application Discontinuation
- 1993-06-23 HU HU9500035A patent/HU221618B1/hu not_active IP Right Cessation
- 1993-06-23 JP JP06502994A patent/JP3094233B2/ja not_active Expired - Fee Related
- 1993-06-23 CZ CZ9544A patent/CZ282168B6/cs not_active IP Right Cessation
1994
- 1994-11-15 EE EE9400128A patent/EE03078B1/xx not_active IP Right Cessation
1995
- 1995-01-04 FI FI950050A patent/FI112321B/fi active
- 1995-01-05 PL PL93307051A patent/PL172503B1/pl not_active IP Right Cessation
- 1995-01-06 NO NO950059A patent/NO306535B1/no not_active IP Right Cessation
1997
- 1997-09-08 GR GR970402286T patent/GR3024648T3/el unknown
1998
- 1998-06-25 HK HK98106760A patent/HK1007503A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR9306800A (pt)	1998-12-08
NO950059D0 (no)	1995-01-06
CA2139781A1 (en)	1994-01-20
NO950059L (no)	1995-01-06
CA2139781C (en)	2003-09-23
HU9500035D0 (en)	1995-03-28
DE69220484T2 (de)	1998-02-05
DE69220484D1 (de)	1997-07-24
DK0577913T3 (da)	1998-01-26
HK1007503A1 (en)	1999-04-16
FI950050A0 (fi)	1995-01-04
NZ253164A (en)	1996-01-26
WO1994001115A1 (en)	1994-01-20
HUT72657A (en)	1996-05-28
EP0577913B1 (de)	1997-06-18
FI112321B (fi)	2003-11-28
GR3024648T3 (en)	1997-12-31
SG49770A1 (en)	1998-06-15
AU678972B2 (en)	1997-06-19
FI950050L (fi)	1995-01-04
JP3094233B2 (ja)	2000-10-03
KR100278851B1 (ko)	2001-01-15
HU221618B1 (hu)	2002-12-28
PL172503B1 (pl)	1997-10-31
CZ282168B6 (cs)	1997-05-14
EP0577913A1 (de)	1994-01-12
ES2106852T3 (es)	1997-11-16
PL307051A1 (en)	1995-05-02
CZ4495A3 (en)	1995-09-13
EE03078B1 (et)	1998-04-15
KR950702422A (ko)	1995-07-29
JPH07508745A (ja)	1995-09-28
AU4329693A (en)	1994-01-31
NO306535B1 (no)	1999-11-22

Legal Events

Date	Code	Title
1998-02-15	UEP	Publication of translation of european patent specification
1998-03-15	EEIH	Change in the person of patent owner
2011-09-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE151640T1 (de)	1997-05-15	Verwendung von protease-inhibitoren als antiexudative, antiphlogistische und antimikrobielle mittel
MX173433B (es)	1994-03-03	Composicion acuosa de ibuprofen y procedimiento para su preparacion
EP0527801A4 (en)	1993-03-10	Thiophene sulfonamides useful as carbonic anydrase inhibitors
MX173727B (es)	1994-03-24	Composicion farmaceutica oral con baja dosifica cion de inhibidor de plaquetas/anticoagulante
ES2184836T3 (es)	2003-04-16	Composiciones que contienen derivados de azol para aplicacion topica en la piel.
ES2098672T3 (es)	1997-05-01	Composiciones farmaceuticas estabilizadas que contienen derivados de vitaminas d2 y d3.
ES2178188T3 (es)	2002-12-16	Composiciones antitusigenas que contienen teobromina.
DE69629989D1 (de)	2003-10-23	Präparate zur äusserlichen anwendung zur behandlung von dermatosen
DK0577913T3 (da)	1998-01-26	Ophthalmisk præparat indeholdende timolol-hemihydrat
ES2113358T3 (es)	1998-05-01	Composiciones antidiarreicas.
ES2037829T3 (es)	1993-07-01	Agentes contra el glaucoma a base de tiofen sulfonamida.
ATE107853T1 (de)	1994-07-15	Orales, melatonin enthaltendes arzneimittel.
ES2069823T3 (es)	1995-05-16	Tratamiento de la hipertension ocular con una combinacion sinergica ocular.
KR930001903A (ko)	1993-02-22	유비데카레논 경구용 수용액 제제
JPS5714517A (en)	1982-01-25	Whitening cosmetic
DK0420798T3 (da)	1994-04-11	Antimikrobielle præparater
AU6922891A (en)	1991-07-11	Improvements in or relating to topical compositions containing 1 alpha 25-dihydroxycholecalciferol
KR880001290A (ko)	1988-04-22	β-차단제 및 필로카르핀-함유 제제
ES2092559T3 (es)	1996-12-01	Formulacion farmaceutica que contiene penciclovir.
ATE33759T1 (de)	1988-05-15	Antimykotische mittel in gelform zur behandlung von pilzinfektionen der mundhoehle.
KR880011161A (ko)	1988-10-26	Ll-f 28249 화합물의 모노-및 디에폭시드 유도체와 그의 사용방법 및 그 유도체를 포함하는 조성물
ES2179667T3 (es)	2003-01-16	Nuevas formulaciones inyectables que contienen ramoplanina.
MX9306467A (es)	1994-05-31	Formulacion novedosa.
IT227086Y1 (it)	1997-09-09	Confezione per sigarette e simili
KR890001567A (ko)	1989-03-27	디플루니살 및 트로메타민-함유 조성물