ATE155343T1 - Verwendung von 2-(4-(-chlorophenyl)cyclohexyl>-3- hydroxy-1,4-naphtoquinon zur behandlung von krebs - Google Patents

Verwendung von 2-(4-(-chlorophenyl)cyclohexyl>-3- hydroxy-1,4-naphtoquinon zur behandlung von krebs

Info

Publication number: ATE155343T1
Authority: AT; Austria
Prior art keywords: treatment; pct; tumours; chlorophenyl; cyclohexyl
Prior art date: 1992-08-07

Application number

AT94906748T

Other languages

English (en)

Inventor

Alan Thomas Hudson

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-08-07

Filing date

1993-08-06

Publication date

1997-08-15

1993-08-06 Application filed by Wellcome Found filed Critical Wellcome Found

1997-08-15 Application granted granted Critical

1997-08-15 Publication of ATE155343T1 publication Critical patent/ATE155343T1/de

Links

206010028980 Neoplasm Diseases 0.000 title abstract 5
201000011510 cancer Diseases 0.000 title 1
241001465754 Metazoa Species 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
BSJMWHQBCZFXBR-UHFFFAOYSA-N 3-[4-(p-chlorophenyl)cyclohexyl]-4-hydroxy-1,2-naphthoquinone Chemical compound O=C1C(=O)C2=CC=CC=C2C(O)=C1C(CC1)CCC1C1=CC=C(Cl)C=C1 BSJMWHQBCZFXBR-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT94906748T 1992-08-07 1993-08-06 Verwendung von 2-(4-(-chlorophenyl)cyclohexyl>-3- hydroxy-1,4-naphtoquinon zur behandlung von krebs ATE155343T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB929216859A GB9216859D0 (en)	1992-08-07	1992-08-07	Medicaments

Publications (1)

Publication Number	Publication Date
ATE155343T1 true ATE155343T1 (de)	1997-08-15

Family

ID=10720039

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94906748T ATE155343T1 (de)	1992-08-07	1993-08-06	Verwendung von 2-(4-(-chlorophenyl)cyclohexyl>-3- hydroxy-1,4-naphtoquinon zur behandlung von krebs

Country Status (11)

Country	Link
US (1)	US5567738A (de)
EP (1)	EP0653936B1 (de)
JP (1)	JPH07509710A (de)
KR (1)	KR950702413A (de)
AT (1)	ATE155343T1 (de)
AU (1)	AU676687B2 (de)
CA (1)	CA2141274A1 (de)
DE (1)	DE69312297T2 (de)
ES (1)	ES2105643T3 (de)
GB (1)	GB9216859D0 (de)
WO (1)	WO1994003163A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5883270A (en) *	1996-02-20	1999-03-16	Wisconsin Alumni Research Foundation	4-substituted-1, 2-naphthoquinones and their use in the inhibition of neoplastic cell growth
AU2001228454A1 (en) *	2000-01-13	2001-07-24	Merck Patent G.M.B.H	Pharmaceutical preparations containing 2-pyrrolidone as the dissolving intermediary
WO2012153162A1 (en)	2011-05-12	2012-11-15	Lupin Limited	Novel method for preparation of atovaquone
WO2013014486A1 (en)	2011-07-28	2013-01-31	Lupin Limited	Improved synthesis of 2-(4-(4-chlorophenyl) cyclohex-1-enyl) -3, 4-dihydronaphthalen-1 (2h)-one; an intermediate for atovaquone
KR101990054B1 (ko) *	2017-04-25	2019-06-17	대구대학교 산학협력단	로손을 유효성분으로 포함하는 항암 조성물
KR20250130660A (ko) *	2023-01-19	2025-09-02	루미스타 바이오테크놀로지 아이엔씨.	칼슘 방출-활성화 칼슘 채널 또는 디스코이딘 도메인 수용체 2 관련 장애 또는 병태의 치료 또는 예방에서의 사용을 위한 약학적 조성물

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2533648A (en) *	1949-03-05	1950-12-12	Joseph H Warburg	Circular saw making
US3347742A (en) *	1965-05-28	1967-10-17	Merck & Co Inc	2-(4-cyclohexylcyclohexyl)-3-hydroxy-1, 4-naphthoquinone in controlling coccidiosis in poultry
US3367830A (en) *	1965-06-23	1968-02-06	Merck & Co Inc	Controlling coccidiosis in poultry with 1,4-naphthoquinones
GB1141735A (en) *	1966-11-23	1969-01-29	Pfizer & Co C	Pharmaceutical anti-tumor composition
US3655699A (en) *	1970-03-02	1972-04-11	Pfizer	Analogues of lapachol as antitumor agents
GB1553424A (en) *	1976-02-10	1979-09-26	Wellcome Found	Method of treating protozal diseases
IL56013A (en) *	1977-11-22	1983-06-15	Wellcome Found	2-cycloalkyl-3-hydroxy-1,4-naphthoquinone derivatives,their preparation and therapeutic compositions containing them
US4485116A (en) *	1981-10-16	1984-11-27	Hudson Alan T	Antiprotozoal compounds
US4485117A (en) *	1981-10-16	1984-11-27	Hudson Alan T	Antiprotozoal compounds
GB8310141D0 (en) *	1983-04-14	1983-05-18	Wellcome Found	Naphthoquinone derivatives
GB8310140D0 (en) *	1983-04-14	1983-05-18	Wellcome Found	Antiprotozoal agents
US5053432A (en) *	1983-04-14	1991-10-01	Burroughs Wellcome Co.	Naphthoquinone derivatives
US5206268A (en) *	1988-08-16	1993-04-27	Burroughs Wellcome Co.	Medicaments
GB8819477D0 (en) *	1988-08-16	1988-09-21	Wellcome Found	Medicaments
NZ230313A (en) *	1988-08-16	1992-07-28	Wellcome Found	Pharmaceutical formulations comprising a naphthoquinone adapted for nasal administration, naphthoquinone derivatives, preparation and use thereof
DE68912262T2 (de) *	1988-10-07	1994-05-11	Sakai Chemical Industry Co	Katalysatoren und Verfahren zur Denitrierung.

1992
- 1992-08-07 GB GB929216859A patent/GB9216859D0/en active Pending
1993
- 1993-08-06 US US08/379,617 patent/US5567738A/en not_active Expired - Lifetime
- 1993-08-06 DE DE69312297T patent/DE69312297T2/de not_active Expired - Lifetime
- 1993-08-06 KR KR1019950700123A patent/KR950702413A/ko not_active Withdrawn
- 1993-08-06 JP JP6505142A patent/JPH07509710A/ja active Pending
- 1993-08-06 AU AU47224/93A patent/AU676687B2/en not_active Ceased
- 1993-08-06 EP EP94906748A patent/EP0653936B1/de not_active Expired - Lifetime
- 1993-08-06 WO PCT/GB1993/001669 patent/WO1994003163A1/en not_active Ceased
- 1993-08-06 AT AT94906748T patent/ATE155343T1/de not_active IP Right Cessation
- 1993-08-06 ES ES94906748T patent/ES2105643T3/es not_active Expired - Lifetime
- 1993-08-06 CA CA002141274A patent/CA2141274A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU4722493A (en)	1994-03-03
EP0653936B1 (de)	1997-07-16
KR950702413A (ko)	1995-07-29
DE69312297D1 (de)	1997-08-21
US5567738A (en)	1996-10-22
CA2141274A1 (en)	1994-02-17
GB9216859D0 (en)	1992-09-23
ES2105643T3 (es)	1997-10-16
WO1994003163A1 (en)	1994-02-17
DE69312297T2 (de)	1997-10-30
EP0653936A1 (de)	1995-05-24
AU676687B2 (en)	1997-03-20
JPH07509710A (ja)	1995-10-26

Legal Events

Date	Code	Title	Description
1998-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
FI971951A0 (fi)	1997-05-07	2,2-dikloroalkaanikarboksyylihapot, menetelmät niiden valmistamiseksi, niitä sisältävät lääkkeet, ja niiden käyttö insuliiniresistanssin hoitoon
DE59401401D1 (de)	1997-02-06	Pharmazeutische formulierung zur behandlung der nicotinabhängigkeit
DE59508961D1 (de)	2001-02-15	Verwendung von weihrauch zur behandlung der alzheimer-krankheit
FI950403A0 (fi)	1995-01-30	Neurosuojaavia yhdisteitä
ATE155343T1 (de)	1997-08-15	Verwendung von 2-(4-(-chlorophenyl)cyclohexyl>-3- hydroxy-1,4-naphtoquinon zur behandlung von krebs
DE69516110D1 (de)	2000-05-11	Verwendung von riluzol zur behandlung mitochondrialer erkrankungen
ATE205399T1 (de)	2001-09-15	Eine lagerstabile wässrige lösung zur infusion die einen thrombininhibitor enthält
ATE190484T1 (de)	2000-04-15	Arzneimittel zur behandlung von durch babesia verursachten protozoeninfektionen
DE68916651D1 (de)	1994-08-11	Heilmittel zur behandlung von toxoplasmose.
DE68916443D1 (de)	1994-07-28	Arzneimittel zur behandlung von kryptosporidiose.
ATE194076T1 (de)	2000-07-15	Verwendung von n,s-diacetylcystein-ethylester (dacee) zur herstellung eines medikaments zur behandlung viraler erkrankungen
GEP19970834B (en)	1997-02-10	2-(4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone
CY1105545T1 (el)	2010-07-28	Θεραπεια στατινης για ενισχυση της διατηρησης νοητικης λειτουργιας
ATE172118T1 (de)	1998-10-15	Verwendung von östriol zur herstellung einen transdermalen therapeutischen systeme zur behandlung von klimakterischer osteoporose
DE60113895D1 (de)	2006-02-23	Verwendung von Tiludronsäure beim Geflügel zur Herstellung eines Arzneimittels zur Prophylaxe und Behandlung von Osteoporose