ATE155686T1 - Hemmung von metastasen bei krebspatienten mit pyridyloxazol-2-onen - Google Patents

Hemmung von metastasen bei krebspatienten mit pyridyloxazol-2-onen

Info

Publication number: ATE155686T1
Authority: AT; Austria
Prior art keywords: ones; metastasis; pyridyloxazole; inhibition; cancer patients
Prior art date: 1991-05-14

Application number

AT92913637T

Other languages

English (en)

Inventor

Alan J Bitonti

Original Assignee

Merrell Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-05-14

Filing date

1992-04-14

Publication date

1997-08-15

1992-04-14 Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc

1997-08-15 Application granted granted Critical

1997-08-15 Publication of ATE155686T1 publication Critical patent/ATE155686T1/de

Links

206010027476 Metastases Diseases 0.000 title abstract 3
206010028980 Neoplasm Diseases 0.000 title abstract 3
201000011510 cancer Diseases 0.000 title abstract 3
230000009401 metastasis Effects 0.000 title abstract 3
230000005764 inhibitory process Effects 0.000 title 1
KJRCCPXLMQDVHA-UHFFFAOYSA-N 4-pyridin-2-yl-3h-1,3-oxazol-2-one Chemical class O1C(=O)NC(C=2N=CC=CC=2)=C1 KJRCCPXLMQDVHA-UHFFFAOYSA-N 0.000 abstract 2
102000003923 Protein Kinase C Human genes 0.000 abstract 1
108090000315 Protein Kinase C Proteins 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT92913637T 1991-05-14 1992-04-14 Hemmung von metastasen bei krebspatienten mit pyridyloxazol-2-onen ATE155686T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US69982191A	1991-05-14	1991-05-14

Publications (1)

Publication Number	Publication Date
ATE155686T1 true ATE155686T1 (de)	1997-08-15

Family

ID=24811050

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92913637T ATE155686T1 (de)	1991-05-14	1992-04-14	Hemmung von metastasen bei krebspatienten mit pyridyloxazol-2-onen

Country Status (12)

Country	Link
US (1)	US5610171A (de)
EP (1)	EP0539575B1 (de)
AT (1)	ATE155686T1 (de)
AU (1)	AU645217B2 (de)
CA (1)	CA2087334A1 (de)
DE (1)	DE69221069T2 (de)
DK (1)	DK0539575T3 (de)
ES (1)	ES2106874T3 (de)
GR (1)	GR3024832T3 (de)
IE (1)	IE921524A1 (de)
NZ (1)	NZ242677A (de)
WO (1)	WO1992020337A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20070009529A1 (en) *	2002-03-26	2007-01-11	New York University	Agents that dissolve arterial thrombi
US8753631B2 (en) *	2009-05-01	2014-06-17	New York University	Therapeutic agents for inducing platelet fragmentation and treating thromboembolic disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2935902A1 (de) *	1979-09-05	1981-04-02	A. Nattermann & Cie GmbH, 5000 Köln	Oxazolinalkansaeuren, deren salze und ester, verfahren zu deren herstellung und diese enthaltende arzneimittel
US4698353A (en) *	1985-11-13	1987-10-06	Merrell Dow Pharmaceuticals Inc.	Cardiotonic heterocyclic oxazolones
US4728661A (en) *	1985-11-13	1988-03-01	Merrell Dow Pharmaceuticals Inc.	Cardiotonic phenyl oxazolones
US4670450A (en) *	1985-11-13	1987-06-02	Merrell Dow Pharmaceuticals Inc.	Cardiotonic thiazolones
DE3827974A1 (de) *	1988-08-18	1990-02-22	Boehringer Mannheim Gmbh	Kombinationspraeparate von proteinkinase-c-inhibitoren mit lipiden, lipid-analoga, cytostatica oder inhibitoren von phospholipasen
ZA908852B (en) *	1989-11-13	1991-09-25	Merrell Dow Pharma	Treatment of multi-drug resistant tumors with pyridyloxazole-2-ones
US5182293A (en) *	1989-11-13	1993-01-26	Merrell Dow Pharmaceuticals Inc.	Treatment of multi-drug resistant tumors with pyridyloxazole-2-ones

1992
- 1992-04-14 AU AU21676/92A patent/AU645217B2/en not_active Ceased
- 1992-04-14 DK DK92913637.2T patent/DK0539575T3/da active
- 1992-04-14 CA CA002087334A patent/CA2087334A1/en not_active Abandoned
- 1992-04-14 AT AT92913637T patent/ATE155686T1/de active
- 1992-04-14 DE DE69221069T patent/DE69221069T2/de not_active Expired - Fee Related
- 1992-04-14 EP EP92913637A patent/EP0539575B1/de not_active Expired - Lifetime
- 1992-04-14 ES ES92913637T patent/ES2106874T3/es not_active Expired - Lifetime
- 1992-04-14 WO PCT/US1992/003062 patent/WO1992020337A2/en not_active Ceased
- 1992-05-11 NZ NZ242677A patent/NZ242677A/en unknown
- 1992-07-01 IE IE152492A patent/IE921524A1/en not_active Application Discontinuation
1995
- 1995-01-03 US US08/368,253 patent/US5610171A/en not_active Expired - Fee Related
1997
- 1997-09-24 GR GR970402470T patent/GR3024832T3/el unknown

Also Published As

Publication number	Publication date
WO1992020337A3 (en)	1993-01-21
NZ242677A (en)	1997-06-24
DE69221069T2 (de)	1997-11-13
IE921524A1 (en)	1992-11-18
AU645217B2 (en)	1994-01-06
DK0539575T3 (da)	1997-10-27
ES2106874T3 (es)	1997-11-16
GR3024832T3 (en)	1998-01-30
DE69221069D1 (de)	1997-08-28
US5610171A (en)	1997-03-11
EP0539575A1 (de)	1993-05-05
AU2167692A (en)	1992-12-30
WO1992020337A2 (en)	1992-11-26
EP0539575B1 (de)	1997-07-23
CA2087334A1 (en)	1992-11-15

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