ATE155996T1 - Polyurethan-biopolymer verbindung - Google Patents
Polyurethan-biopolymer verbindungInfo
- Publication number
- ATE155996T1 ATE155996T1 AT91911897T AT91911897T ATE155996T1 AT E155996 T1 ATE155996 T1 AT E155996T1 AT 91911897 T AT91911897 T AT 91911897T AT 91911897 T AT91911897 T AT 91911897T AT E155996 T1 ATE155996 T1 AT E155996T1
- Authority
- AT
- Austria
- Prior art keywords
- polyurethane
- biopolymer compound
- bioactive agent
- biopolymer
- compound
- Prior art date
Links
- 229920001222 biopolymer Polymers 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 239000012867 bioactive agent Substances 0.000 abstract 2
- 238000013270 controlled release Methods 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
- A61L15/325—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6415—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63 having nitrogen
- C08G18/6446—Proteins and derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6484—Polysaccharides and derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00902—Plasters containing means
- A61F2013/00906—Plasters containing means for transcutaneous or transdermal drugs application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00902—Plasters containing means
- A61F2013/0091—Plasters containing means with disinfecting or anaesthetics means, e.g. anti-mycrobic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Polyurethanes Or Polyureas (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53999090A | 1990-06-14 | 1990-06-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE155996T1 true ATE155996T1 (de) | 1997-08-15 |
Family
ID=24153514
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91911897T ATE155996T1 (de) | 1990-06-14 | 1991-06-14 | Polyurethan-biopolymer verbindung |
| AT96203619T ATE204151T1 (de) | 1990-06-14 | 1991-06-14 | Wundverband und katheterhalterung aus einem polyurethan-biopolymer kompositmaterial |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96203619T ATE204151T1 (de) | 1990-06-14 | 1991-06-14 | Wundverband und katheterhalterung aus einem polyurethan-biopolymer kompositmaterial |
Country Status (8)
| Country | Link |
|---|---|
| EP (3) | EP0533809B1 (de) |
| JP (1) | JP3046623B2 (de) |
| AT (2) | ATE155996T1 (de) |
| CA (1) | CA2085255C (de) |
| DE (2) | DE69132692T2 (de) |
| DK (1) | DK0533809T3 (de) |
| ES (1) | ES2160207T3 (de) |
| WO (1) | WO1991019470A1 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5833665A (en) * | 1990-06-14 | 1998-11-10 | Integra Lifesciences I, Ltd. | Polyurethane-biopolymer composite |
| GB9213773D0 (en) * | 1992-06-29 | 1992-08-12 | Cv Lab Ltd | Dual release alginate fibre |
| US5503844A (en) * | 1993-05-18 | 1996-04-02 | Mli Acquisition Corp. Ii | Foam laminate transdermal patch |
| US7662409B2 (en) | 1998-09-25 | 2010-02-16 | Gel-Del Technologies, Inc. | Protein matrix materials, devices and methods of making and using thereof |
| JP3557356B2 (ja) * | 1998-11-04 | 2004-08-25 | 株式会社大塚製薬工場 | 血管カテーテル刺入部の衛生管理用パッチ |
| US6309454B1 (en) | 2000-05-12 | 2001-10-30 | Johnson & Johnson Medical Limited | Freeze-dried composite materials and processes for the production thereof |
| CA2349989A1 (en) * | 2001-06-07 | 2002-12-07 | Paul J. Santerre | Bioactive surface modifiers for polymers and articles made therefrom |
| GB0215023D0 (en) * | 2002-06-28 | 2002-08-07 | Bristol Myers Squibb Co | Wound dressing |
| CA2518408A1 (en) | 2003-03-14 | 2004-09-23 | Sartomer Technology Co., Inc. | Controlled release polymeric gels |
| US8465537B2 (en) | 2003-06-17 | 2013-06-18 | Gel-Del Technologies, Inc. | Encapsulated or coated stent systems |
| WO2005055945A2 (en) | 2003-12-08 | 2005-06-23 | Gel-Del Technologies, Inc. | Mucoadhesive drug delivery devices and methods of making and using thereof |
| DE102004031955A1 (de) * | 2004-06-24 | 2006-01-12 | Paul Hartmann Ag | Wundauflage |
| EP1771490B1 (de) * | 2004-07-26 | 2019-01-02 | Synthes GmbH | Biokompatible, bioabbaubare polyurethan werkstoffe mit kontrolliertem hydrophob zu hydrophil verhältnis |
| JP4786189B2 (ja) * | 2005-02-01 | 2011-10-05 | リンテック株式会社 | 皮膚貼付用粘着剤組成物および皮膚貼付用粘着シート |
| US11890371B2 (en) | 2007-12-26 | 2024-02-06 | Petvivo Holdings, Inc. | Biocompatible protein-based particles and methods thereof |
| EP2403888B1 (de) | 2009-03-06 | 2021-05-12 | Evertree | Proteinhaltige emulsionen und haftstoffe sowie ihre herstellung und verwendung |
| CN102439058B (zh) * | 2009-03-06 | 2015-07-29 | 生物高聚物技术有限公司 | 含有蛋白的泡沫材料,它们的制造与用途 |
| CA2801262C (en) | 2010-06-07 | 2021-02-09 | Biopolymer Technologies, Ltd. | Protein-containing adhesives, and manufacture and use thereof |
| JP5631783B2 (ja) * | 2011-03-11 | 2014-11-26 | 株式会社イノアック技術研究所 | 抗菌用ポリウレタン |
| EP3181577A1 (de) | 2011-09-09 | 2017-06-21 | Evertree | Proteinhaltige haftstoffe und herstellung und verwendung davon |
| US20130065012A1 (en) | 2011-09-09 | 2013-03-14 | Anthony A. Parker | Protein-containing adhesives, and manufacture and use thereof |
| EP2880116B1 (de) | 2012-07-30 | 2020-02-05 | Evertree | Proteinklebstoffe mit einer anhydrid-, carbonsäure- und/oder carboxylatsalzverbindung und ihre verwendung |
| US8969649B2 (en) * | 2012-08-10 | 2015-03-03 | Ethicon, Inc. | Integrated dressing device |
| US10422158B2 (en) | 2012-12-20 | 2019-09-24 | SafeHandles, LLC | Replaceable antimicrobial system |
| EP2907502A1 (de) * | 2014-02-17 | 2015-08-19 | Ferrari S.r.l. | Schnittstellenmembran für Kontakt mit der Haut |
| EP2944565B1 (de) | 2014-05-13 | 2017-09-27 | Entrotech, Inc. | Erosionsschutzhülle |
| EP3600441A1 (de) | 2017-03-22 | 2020-02-05 | Genentech, Inc. | Hydrogelvernetzte hyaluronsäure-prodrug-zusammensetzungen und verfahren |
| EP3706689A4 (de) * | 2017-11-08 | 2021-12-01 | University Of Massachusetts | Postoperativer hybridverband zur optimierung von hautimplantatverfahren in der rekonstruktionschirurgie |
| CN113425501A (zh) * | 2021-05-31 | 2021-09-24 | 振德医疗用品股份有限公司 | 一种负压引流护创敷料及负压引流护创装置 |
| WO2023053884A1 (ja) * | 2021-09-29 | 2023-04-06 | テルモ株式会社 | 貼着デバイス及び貼着方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2748882A1 (de) * | 1977-11-02 | 1979-05-03 | Arnis Dr Med Rava | Pflaster fuer einen antibakteriellen wundschutz insbesondere beim anlegen von intravenoesen kathetern |
| CA1190855A (en) * | 1980-09-03 | 1985-07-23 | Rolf W. Pfirrmann | Treatment of osteitis |
| EP0119248B1 (de) * | 1982-09-13 | 1989-04-12 | Hydromer, Inc. | Antibakteriell wirkender medizinischer werkstoff und vorrichtung |
| GB8319766D0 (en) * | 1983-07-22 | 1983-08-24 | Graham N B | Controlled release device |
| EP0161043A3 (de) * | 1984-03-02 | 1986-04-16 | The Dow Chemical Company | Verfahren zur Immobilisierung von Enzymen |
| DE3684887D1 (de) * | 1985-11-29 | 1992-05-21 | Biomatrix Inc | Arzneistoffabgabesysteme auf basis von hyaluronan, dessen derivaten und salzen sowie verfahren zu deren herstellung. |
| US4847049A (en) | 1985-12-18 | 1989-07-11 | Vitaphore Corporation | Method of forming chelated collagen having bactericidal properties |
| US4915694A (en) * | 1987-10-02 | 1990-04-10 | Vitaphore Corporation | Antimicrobial wound dressing and skin fixator for percutaneous conduits |
| US4861652A (en) * | 1987-10-13 | 1989-08-29 | Kimberly-Clark Corporation | Diaper article with elasticized waist panel |
| IT1219587B (it) * | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | Polisaccaridi carbossiilici autoreticolati |
| DE3836828A1 (de) * | 1988-10-28 | 1990-05-03 | Pfrimmer Kabi Gmbh & Co Kg | Haftverband fuer intravenoese periphere kanuelen |
| US5162430A (en) * | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
-
1991
- 1991-06-14 ES ES96203619T patent/ES2160207T3/es not_active Expired - Lifetime
- 1991-06-14 JP JP3511258A patent/JP3046623B2/ja not_active Expired - Lifetime
- 1991-06-14 DK DK91911897.6T patent/DK0533809T3/da active
- 1991-06-14 EP EP91911897A patent/EP0533809B1/de not_active Expired - Lifetime
- 1991-06-14 CA CA002085255A patent/CA2085255C/en not_active Expired - Lifetime
- 1991-06-14 EP EP01200967A patent/EP1120112A3/de not_active Withdrawn
- 1991-06-14 DE DE69132692T patent/DE69132692T2/de not_active Expired - Lifetime
- 1991-06-14 WO PCT/US1991/004095 patent/WO1991019470A1/en not_active Ceased
- 1991-06-14 AT AT91911897T patent/ATE155996T1/de not_active IP Right Cessation
- 1991-06-14 EP EP96203619A patent/EP0797965B1/de not_active Expired - Lifetime
- 1991-06-14 DE DE69127081T patent/DE69127081T2/de not_active Expired - Lifetime
- 1991-06-14 AT AT96203619T patent/ATE204151T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0797965B1 (de) | 2001-08-16 |
| DE69127081T2 (de) | 1998-02-05 |
| EP1120112A2 (de) | 2001-08-01 |
| DE69127081D1 (de) | 1997-09-04 |
| CA2085255C (en) | 2001-10-09 |
| CA2085255A1 (en) | 1991-12-15 |
| EP0533809B1 (de) | 1997-07-30 |
| ATE204151T1 (de) | 2001-09-15 |
| EP0797965A1 (de) | 1997-10-01 |
| DK0533809T3 (da) | 1997-08-25 |
| JP3046623B2 (ja) | 2000-05-29 |
| JPH05507925A (ja) | 1993-11-11 |
| EP1120112A3 (de) | 2001-11-14 |
| EP0533809A1 (de) | 1993-03-31 |
| WO1991019470A1 (en) | 1991-12-26 |
| DE69132692T2 (de) | 2002-07-04 |
| ES2160207T3 (es) | 2001-11-01 |
| DE69132692D1 (de) | 2001-09-20 |
| EP0533809A4 (en) | 1994-09-07 |
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