ATE157365T1 - Thiophenverbindungen und ihre pharmazeutischen verwendungen - Google Patents

Thiophenverbindungen und ihre pharmazeutischen verwendungen

Info

Publication number: ATE157365T1
Authority: AT; Austria
Prior art keywords: alkyl; thiophene compounds; alkanoyl; heteroaryl; aryl
Prior art date: 1989-10-31

Application number

AT90120538T

Other languages

English (en)

Inventor

Tohru Nakao

Hiroshi Tanaka

Yasuto Morimoto

Shuzo Takehara

Original Assignee

Yoshitiomi Pharmaceutical Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-31

Filing date

1990-10-26

Publication date

1997-09-15

1990-10-26 Application filed by Yoshitiomi Pharmaceutical Ind filed Critical Yoshitiomi Pharmaceutical Ind

1997-09-15 Application granted granted Critical

1997-09-15 Publication of ATE157365T1 publication Critical patent/ATE157365T1/de

Links

YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical class C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 13
125000002252 acyl group Chemical group 0.000 abstract 5
150000003577 thiophenes Chemical class 0.000 abstract 4
125000003118 aryl group Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 3
150000002367 halogens Chemical class 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
-1 nitro, amino Chemical group 0.000 abstract 3
125000004765 (C1-C4) haloalkyl group Chemical group 0.000 abstract 2
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
125000001072 heteroaryl group Chemical group 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000005236 alkanoylamino group Chemical group 0.000 abstract 1
229940125713 antianxiety drug Drugs 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
239000003326 hypnotic agent Substances 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
239000002664 nootropic agent Substances 0.000 abstract 1
230000001777 nootropic effect Effects 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT90120538T 1989-10-31 1990-10-26 Thiophenverbindungen und ihre pharmazeutischen verwendungen ATE157365T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP28549589		1989-10-31
JP32683989		1989-12-15
JP7158290		1990-03-20

Publications (1)

Publication Number	Publication Date
ATE157365T1 true ATE157365T1 (de)	1997-09-15

Family

ID=27300695

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90120538T ATE157365T1 (de)	1989-10-31	1990-10-26	Thiophenverbindungen und ihre pharmazeutischen verwendungen

Country Status (6)

Country	Link
US (2)	US5175162A (de)
EP (2)	EP0426018B1 (de)
JP (1)	JP2969911B2 (de)
AT (1)	ATE157365T1 (de)
CA (1)	CA2028496A1 (de)
DE (1)	DE69031331D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5597918A (en) *	1991-08-27	1997-01-28	Yoshitomi Pharmaceutical Industries, Ltd.	Fused pyridazine compound
WO1993004069A1 (fr) *	1991-08-27	1993-03-04	Yoshitomi Pharmaceutical Industries, Ltd.	Compose de pyridazine lie par fusion et utilisation pharmaceutique d'un tel compose
US6673692B2 (en)	2000-06-28	2004-01-06	Micron Technology, Inc.	Method and apparatus for marking microelectronic dies and microelectronic devices
US7138394B2 (en) *	2002-09-27	2006-11-21	Alpharx Inc.	Vehicle for topical delivery of anti-inflammatory compounds
US20060241175A1 (en) *	2002-09-27	2006-10-26	Joseph Schwarz	Vehicle for topical delivery of anti-inflammatory compounds
US20100300564A1 (en) *	2009-06-02	2010-12-02	Ward David P	Ammonia application system including an ammonia dividing manifold with vapor stripper venturi

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4092325A (en) *	1976-12-10	1978-05-30	Warner-Lambert Company	5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof
JPH06763B2 (ja) *	1984-08-28	1994-01-05	吉富製薬株式会社	ベンゾ〔ｈ〕シンノリン誘導体
US4863922A (en) *	1984-12-12	1989-09-05	Merck & Co., Inc.	Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
JPH0633277B2 (ja) *	1986-01-10	1994-05-02	吉富製薬株式会社	ベンゾチオピラノ〔４，３−ｃ〕ピリダジン化合物
DE3867086D1 (de) *	1987-03-02	1992-02-06	Yoshitomi Pharmaceutical	Benzothiepino(5,4-c)pyridazin-verbindungen und ihre pharmazeutischen wirkungen.
EP0308515B1 (de) *	1987-03-25	1994-01-26	Yoshitomi Pharmaceutical Industries, Ltd.	Thienocinnolinverbindungen und deren verwendung als heilmittel
US5153194A (en) *	1988-09-21	1992-10-06	Yoshitomi Pharmaceutical Industries, Ltd.	Thienocycloheptapyridazine compounds and their pharmaceutical use

1990
- 1990-10-24 CA CA002028496A patent/CA2028496A1/en not_active Abandoned
- 1990-10-26 DE DE69031331T patent/DE69031331D1/de not_active Expired - Lifetime
- 1990-10-26 EP EP90120538A patent/EP0426018B1/de not_active Expired - Lifetime
- 1990-10-26 AT AT90120538T patent/ATE157365T1/de not_active IP Right Cessation
- 1990-10-26 EP EP96106520A patent/EP0729960A1/de not_active Withdrawn
- 1990-10-29 JP JP2292562A patent/JP2969911B2/ja not_active Expired - Lifetime
- 1990-10-30 US US07/605,301 patent/US5175162A/en not_active Expired - Fee Related
1992
- 1992-07-30 US US07/921,725 patent/US5329016A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2969911B2 (ja)	1999-11-02
EP0426018A3 (en)	1991-12-11
US5175162A (en)	1992-12-29
CA2028496A1 (en)	1991-05-01
EP0729960A1 (de)	1996-09-04
EP0426018A2 (de)	1991-05-08
EP0426018B1 (de)	1997-08-27
JPH03279386A (ja)	1991-12-10
DE69031331D1 (de)	1997-10-02
US5329016A (en)	1994-07-12

Legal Events

Date	Code	Title	Description
1998-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69617788D1 (de)	2002-01-24	Aromatische Hydroxamsäure-Verbindungen, ihre Herstellung und Verwendung
PT747374E (pt)	2002-05-31	Benzopiranos substituidos com sulfonamido activadores dos canais do potassio
NL300034I2 (nl)	2001-05-01	Gesubstitueerde thiahzolidinedionderivaten.
BR1100970A (pt)	1999-12-07	Composto, e, composição farmacêutica útil no tratamento de doença cardiovascular, tal como hipertensão e deficiência cardìaca congestiva
PT976748E (pt)	2004-03-31	Derivados de pirrolidina com actividade inibidora de fosfolipase a2
ATE307122T1 (de)	2005-11-15	Isoxazolderivate und ihre verwendung als herbizide
HUT70194A (en)	1995-09-28	Quinoline- or quinazoline derivatives, process for producing them and pharmaceutical compositions containing them
AU652981B2 (en)	1994-09-15	Condensed benzoxa ring compound, production thereof, and pharmaceutical composition containing the same
FI895185A0 (fi)	1989-11-01	Mevalonolaktoner av tienopyridintyp.
AU755654C (en)	2007-03-29	Novel amide compounds and drugs containing the same
ATE228518T1 (de)	2002-12-15	Amid derivate
EP0861831A4 (de)	1998-11-11	Heteroaryl substituierte acryloylguanidin-derivate und ihre medizinische zusammensetsungen
DE69031331D1 (de)	1997-10-02	Thiophenverbindungen und ihre pharmazeutischen Verwendungen
PT1057827E (pt)	2003-11-28	Derivados da espiropiperidina
NO934760L (no)	1994-06-24	Arylsubstituerte heterosykliske forbindelser
HUT70446A (en)	1995-10-30	Pyridine derivatives, process for producing them and pharmaceutical compositions comprising them
EP1020451A4 (de)	2001-06-13	Neue anilidverbindungen und medikamente, die diese enthalten
HUT69392A (en)	1995-09-28	Alkylenediamine derivatives, pharmaceutical compositions containing them and process for their preparation
NZ329604A (en)	2000-03-27	Isoxazole derivatives substituted by an amino, guanidinyl or azacycloalkyl-oxy, -sulphinyl or -sulphenyl group, pharmaceutical compositions comprising them