ATE157769T1 - Strömungssteuermittel für flüssigkeiten - Google Patents

Strömungssteuermittel für flüssigkeiten

Info

Publication number
ATE157769T1
ATE157769T1 AT94917683T AT94917683T ATE157769T1 AT E157769 T1 ATE157769 T1 AT E157769T1 AT 94917683 T AT94917683 T AT 94917683T AT 94917683 T AT94917683 T AT 94917683T AT E157769 T1 ATE157769 T1 AT E157769T1
Authority
AT
Austria
Prior art keywords
liquids
control means
flow control
liquid
small
Prior art date
Application number
AT94917683T
Other languages
English (en)
Inventor
Christopher David Bevan
Ian Martin Mutton
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939311651A external-priority patent/GB9311651D0/en
Priority claimed from GB9401711A external-priority patent/GB9401711D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE157769T1 publication Critical patent/ATE157769T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16LPIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L55/00Devices or appurtenances for use in, or in connection with, pipes or pipe systems
    • F16L55/10Means for stopping flow in pipes or hoses
    • F16L55/103Means for stopping flow in pipes or hoses by temporarily freezing liquid sections in the pipe
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1888Pipettes or dispensers with temperature control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/30Control of physical parameters of the fluid carrier of temperature
    • G01N2030/3038Control of physical parameters of the fluid carrier of temperature temperature control of column exit, e.g. of restrictors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/16Injection
    • G01N30/20Injection using a sampling valve
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6095Micromachined or nanomachined, e.g. micro- or nanosize
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S366/00Agitating
    • Y10S366/03Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/0318Processes
    • Y10T137/0391Affecting flow by the addition of material or energy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Pipe Accessories (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Vehicle Body Suspensions (AREA)
  • Gas Separation By Absorption (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • External Artificial Organs (AREA)
AT94917683T 1993-06-05 1994-06-03 Strömungssteuermittel für flüssigkeiten ATE157769T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939311651A GB9311651D0 (en) 1993-06-05 1993-06-05 Liquid flow control means
GB9401711A GB9401711D0 (en) 1994-01-29 1994-01-29 Improvements relating to mocro-analytical techniques

Publications (1)

Publication Number Publication Date
ATE157769T1 true ATE157769T1 (de) 1997-09-15

Family

ID=26303013

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94917683T ATE157769T1 (de) 1993-06-05 1994-06-03 Strömungssteuermittel für flüssigkeiten

Country Status (10)

Country Link
US (3) US5795788A (de)
EP (1) EP0701688B1 (de)
JP (1) JP3772990B2 (de)
AT (1) ATE157769T1 (de)
AU (1) AU6930894A (de)
DE (1) DE69405394T2 (de)
DK (1) DK0701688T3 (de)
ES (1) ES2107228T3 (de)
FI (1) FI955823A7 (de)
WO (1) WO1994029690A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE157769T1 (de) * 1993-06-05 1997-09-15 Glaxo Group Ltd Strömungssteuermittel für flüssigkeiten
US6048734A (en) * 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
FR2764696B1 (fr) * 1997-06-17 1999-08-13 Inst Francais Du Petrole Dispositif de prelevement d'echantillons de fluide comportant une vanne de controle a commande thermique
FI981432A7 (fi) 1998-06-22 2000-01-14 Niilo Kaartinen Jäähana
US6387234B1 (en) * 1998-08-31 2002-05-14 Iowa State University Research Foundation, Inc. Integrated multiplexed capillary electrophoresis system
US6533914B1 (en) * 1999-07-08 2003-03-18 Shaorong Liu Microfabricated injector and capillary array assembly for high-resolution and high throughput separation
US6716328B1 (en) 2000-03-29 2004-04-06 The Regents Of The University Of California Microchannel cross load array with dense parallel input
JP3628611B2 (ja) * 2000-11-29 2005-03-16 独立行政法人科学技術振興機構 マイクロシステムにおける流れの制御方法
US20020129664A1 (en) * 2001-01-16 2002-09-19 Jorgenson James W. Non-invasive real-time flow meter and related flow measuring method
US20050189225A1 (en) * 2001-02-09 2005-09-01 Shaorong Liu Apparatus and method for small-volume fluid manipulation and transportation
US6768312B2 (en) * 2001-06-06 2004-07-27 United Technologies Corporation Structural integrity monitoring system including wireless electromechanical impedance measurement
FR2831081B1 (fr) 2001-10-24 2004-09-03 Commissariat Energie Atomique Dispositif d'injection parallelisee et synchronisee pour injections sequentielles de reactifs differents
US6557575B1 (en) 2001-11-19 2003-05-06 Waters Investments Limited Fluid flow control freeze/thaw valve for narrow bore capillaries or microfluidic devices
US6704200B2 (en) * 2002-02-12 2004-03-09 Hewlett-Packard Development Company, L.P. Loop thermosyphon using microchannel etched semiconductor die as evaporator
AU2003272397A1 (en) * 2002-09-16 2004-04-30 Waters Investments Limited Freeze-thaw valve limiting cryogenic usage
DE10393861B4 (de) * 2002-12-09 2016-12-15 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Vorrichtung für eine Gefrier-Tau-Ventilschaltung und Verfahren zum Schalten eines Gefrier-Tau-Ventils
US7396512B2 (en) * 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
KR100647282B1 (ko) * 2003-12-24 2006-11-17 삼성전자주식회사 DNA 마이크로어레이 스폿팅(Spoting) 장치 및이를 이용한 스폿팅 방법
JP4782701B2 (ja) * 2004-01-23 2011-09-28 ウオーターズ・テクノロジーズ・コーポレイシヨン 液体クロマトグラフィーのための試料注入システム
US7204264B2 (en) * 2004-04-21 2007-04-17 Waters Investments Ltd. High pressure capillary micro-fluidic valve device and a method of fabricating same
US7694694B2 (en) * 2004-05-10 2010-04-13 The Aerospace Corporation Phase-change valve apparatuses
US8642353B2 (en) * 2004-05-10 2014-02-04 The Aerospace Corporation Microfluidic device for inducing separations by freezing and associated method
US7686040B2 (en) * 2004-06-24 2010-03-30 The Aerospace Corporation Electro-hydraulic devices
US7650910B2 (en) * 2004-06-24 2010-01-26 The Aerospace Corporation Electro-hydraulic valve apparatuses
US7721762B2 (en) * 2004-06-24 2010-05-25 The Aerospace Corporation Fast acting valve apparatuses
US8507050B2 (en) * 2008-11-12 2013-08-13 Ppg Industries Ohio, Inc. Methods for depositing ultra thin coatings exhibiting low haze and methods for the preparation of such coatings
USD666098S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666492S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666096S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666097S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666493S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666099S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container

Family Cites Families (9)

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US3663203A (en) * 1969-04-01 1972-05-16 Columbia Gas Syst Melting of fusible materials
US4258740A (en) * 1977-05-16 1981-03-31 Packard Instrument Company, Inc. Fluid flow control device
GB2019995B (en) * 1978-04-10 1982-09-29 Kaartinen N Method and apparatus for handling batches of liquids
US4203472A (en) * 1978-06-20 1980-05-20 Dulaney Burrell C Device for stopping fluid flow from a pipe
FI70331C (fi) * 1985-04-12 1986-09-15 Fluilogic Systems Oy Foerfarande foer framstaellning av till en behandlingsenhet for vaetskemaengd hoerande genom nedfrysning staengbara kra na samt genom foerfarande framstaelld behandlingsenhet
GB8816499D0 (en) * 1988-07-12 1988-08-17 C J S Sciences Ltd Valve
FI86229C (fi) * 1989-04-10 1992-07-27 Niilo Kaartinen Foerfarande foer formning av ett uppvaermbart och nedkylbart element vid ett system behandlande smao vaetskemaengder samt ett medelst foerfarandet framstaellt element.
CA2016981C (en) * 1989-06-12 1994-09-27 Mark Joseph Devaney, Jr. Temperature control device and reaction vessel
ATE157769T1 (de) * 1993-06-05 1997-09-15 Glaxo Group Ltd Strömungssteuermittel für flüssigkeiten

Also Published As

Publication number Publication date
FI955823A0 (fi) 1995-12-04
AU6930894A (en) 1995-01-03
US6342184B1 (en) 2002-01-29
US6159744A (en) 2000-12-12
ES2107228T3 (es) 1997-11-16
WO1994029690A1 (en) 1994-12-22
FI955823L (fi) 1995-12-04
DE69405394D1 (de) 1997-10-09
JP3772990B2 (ja) 2006-05-10
DK0701688T3 (da) 1998-04-14
FI955823A7 (fi) 1995-12-04
EP0701688B1 (de) 1997-09-03
US5795788A (en) 1998-08-18
DE69405394T2 (de) 1998-01-08
EP0701688A1 (de) 1996-03-20
JPH09502517A (ja) 1997-03-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee