ATE158590T1 - Die zellhaftung an s-laminin inhibitierende peptide - Google Patents

Die zellhaftung an s-laminin inhibitierende peptide

Info

Publication number
ATE158590T1
ATE158590T1 AT90870110T AT90870110T ATE158590T1 AT E158590 T1 ATE158590 T1 AT E158590T1 AT 90870110 T AT90870110 T AT 90870110T AT 90870110 T AT90870110 T AT 90870110T AT E158590 T1 ATE158590 T1 AT E158590T1
Authority
AT
Austria
Prior art keywords
laminin
cell adhesion
inhibiting cell
peptides inhibiting
peptides
Prior art date
Application number
AT90870110T
Other languages
English (en)
Inventor
Dale Donald Hunter
John Paul Merlie
Joshua Richard Sanes
Steven Paul Adams
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Application granted granted Critical
Publication of ATE158590T1 publication Critical patent/ATE158590T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT90870110T 1989-07-19 1990-07-16 Die zellhaftung an s-laminin inhibitierende peptide ATE158590T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/382,606 US5003044A (en) 1989-07-19 1989-07-19 Peptide inhibitors of motor neuron attachment to s-laminin

Publications (1)

Publication Number Publication Date
ATE158590T1 true ATE158590T1 (de) 1997-10-15

Family

ID=23509701

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90870110T ATE158590T1 (de) 1989-07-19 1990-07-16 Die zellhaftung an s-laminin inhibitierende peptide

Country Status (7)

Country Link
US (1) US5003044A (de)
EP (1) EP0412951B1 (de)
AT (1) ATE158590T1 (de)
DE (1) DE69031484T2 (de)
DK (1) DK0412951T3 (de)
ES (1) ES2108010T3 (de)
GR (1) GR3025443T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219837A (en) * 1990-06-21 1993-06-15 Trustees Of The University Of Pennsylvania Method of stimulating myelination of cells
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5580960A (en) * 1993-10-22 1996-12-03 The General Hospital Corporation KS-laminin and methods of use
US5610031A (en) 1993-10-27 1997-03-11 The General Hospital Corporation B1k chain of laminin and methods of use

Also Published As

Publication number Publication date
EP0412951B1 (de) 1997-09-24
DE69031484T2 (de) 1998-04-23
DE69031484D1 (de) 1997-10-30
US5003044A (en) 1991-03-26
EP0412951A1 (de) 1991-02-13
GR3025443T3 (en) 1998-02-27
ES2108010T3 (es) 1997-12-16
DK0412951T3 (da) 1998-02-02

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