ATE159011T1 - Stereoselektives verfahren zur herstellung von 2- amino-ethanol-derivaten mit zentralanalgetischer aktivität und zwischenprodukten - Google Patents
Stereoselektives verfahren zur herstellung von 2- amino-ethanol-derivaten mit zentralanalgetischer aktivität und zwischenproduktenInfo
- Publication number
- ATE159011T1 ATE159011T1 AT91103554T AT91103554T ATE159011T1 AT E159011 T1 ATE159011 T1 AT E159011T1 AT 91103554 T AT91103554 T AT 91103554T AT 91103554 T AT91103554 T AT 91103554T AT E159011 T1 ATE159011 T1 AT E159011T1
- Authority
- AT
- Austria
- Prior art keywords
- amino
- production
- analgesic activity
- intermediate products
- stereoselective process
- Prior art date
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000000707 stereoselective effect Effects 0.000 title abstract 2
- 150000002169 ethanolamines Chemical class 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19856A IT1239950B (it) | 1990-03-28 | 1990-03-28 | Processo per la preparazione di composti con attivita' analgesica centrale |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE159011T1 true ATE159011T1 (de) | 1997-10-15 |
Family
ID=11161831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91103554T ATE159011T1 (de) | 1990-03-28 | 1991-03-08 | Stereoselektives verfahren zur herstellung von 2- amino-ethanol-derivaten mit zentralanalgetischer aktivität und zwischenprodukten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5142066A (de) |
| EP (1) | EP0449011B1 (de) |
| JP (1) | JPH06279400A (de) |
| AT (1) | ATE159011T1 (de) |
| DE (1) | DE69127846T2 (de) |
| IT (1) | IT1239950B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004069793A2 (en) | 2003-01-28 | 2004-08-19 | Bristol-Myers Squibb Company | Novel 2-substituted cyclic amines as calcium sensing receptor modulators |
| US7205322B2 (en) | 2003-02-12 | 2007-04-17 | Bristol-Myers Squibb Company | Thiazolidine compounds as calcium sensing receptor modulators |
| US7265145B2 (en) | 2003-05-28 | 2007-09-04 | Bristol-Myers Squibb Company | Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3775431A (en) * | 1970-12-30 | 1973-11-27 | Mobil Oil Corp | Pyrrolidones from ypsilon-butyrolactones using a zeolite catalyst |
| EP0257831B1 (de) * | 1986-07-31 | 1992-01-29 | Nippon Shokubai Co., Ltd. | Verfahren zur Herstellung von Maleimiden |
| US4999360A (en) * | 1987-12-21 | 1991-03-12 | Monsanto Company | Method of inhibiting virus |
| DE3813416A1 (de) * | 1988-04-21 | 1989-11-02 | Hoechst Ag | 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte |
| CA1336333C (en) * | 1988-05-20 | 1995-07-18 | Davide Della Bella | Pyrrolidone-2 compounds and their use for central analgesic activity |
| DD279669A1 (de) * | 1989-01-31 | 1990-06-13 | Akad Wissenschaften Ddr | Verfahren zur herstellung von 1-aryl-3,5-bis(arylamino)-4-halogen-3-pyrrolin-2-onen |
-
1990
- 1990-03-28 IT IT19856A patent/IT1239950B/it active IP Right Grant
-
1991
- 1991-03-08 EP EP91103554A patent/EP0449011B1/de not_active Expired - Lifetime
- 1991-03-08 DE DE69127846T patent/DE69127846T2/de not_active Expired - Fee Related
- 1991-03-08 AT AT91103554T patent/ATE159011T1/de not_active IP Right Cessation
- 1991-03-20 US US07/672,685 patent/US5142066A/en not_active Expired - Lifetime
- 1991-03-27 JP JP3133774A patent/JPH06279400A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IT9019856A0 (it) | 1990-03-28 |
| EP0449011A3 (en) | 1992-05-27 |
| EP0449011B1 (de) | 1997-10-08 |
| DE69127846T2 (de) | 1998-05-14 |
| JPH06279400A (ja) | 1994-10-04 |
| EP0449011A2 (de) | 1991-10-02 |
| IT1239950B (it) | 1993-11-27 |
| DE69127846D1 (de) | 1997-11-13 |
| US5142066A (en) | 1992-08-25 |
| IT9019856A1 (it) | 1991-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |