ATE160144T1 - Pyridazinon derivate, herstellungsverfahren und verwendung - Google Patents
Pyridazinon derivate, herstellungsverfahren und verwendungInfo
- Publication number
- ATE160144T1 ATE160144T1 AT94119888T AT94119888T ATE160144T1 AT E160144 T1 ATE160144 T1 AT E160144T1 AT 94119888 T AT94119888 T AT 94119888T AT 94119888 T AT94119888 T AT 94119888T AT E160144 T1 ATE160144 T1 AT E160144T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- carbon atoms
- integer
- pyridazinone derivatives
- atom
- Prior art date
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34340593 | 1993-12-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE160144T1 true ATE160144T1 (de) | 1997-11-15 |
Family
ID=18361263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94119888T ATE160144T1 (de) | 1993-12-16 | 1994-12-15 | Pyridazinon derivate, herstellungsverfahren und verwendung |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5604226A (de) |
| EP (1) | EP0658555B1 (de) |
| KR (1) | KR950017967A (de) |
| CN (1) | CN1109878A (de) |
| AT (1) | ATE160144T1 (de) |
| AU (1) | AU675889B2 (de) |
| CA (1) | CA2138224A1 (de) |
| DE (1) | DE69406763T2 (de) |
| DK (1) | DK0658555T3 (de) |
| ES (1) | ES2112470T3 (de) |
| GR (1) | GR3026006T3 (de) |
| NZ (1) | NZ270130A (de) |
| TW (1) | TW326041B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9514160D0 (en) * | 1994-07-25 | 1995-09-13 | Zeneca Ltd | Aromatic compounds |
| NZ512754A (en) * | 1998-12-07 | 2002-10-25 | Nissan Chemical Ind Ltd | Remedial agent for erectile dysfunction containing a 3(2H)-pyridazinone derivative |
| KR100811865B1 (ko) * | 2006-12-08 | 2008-03-10 | 주식회사 레고켐 바이오사이언스 | 인자 Ⅶａ 억제 활성을 갖는 피리미디논 또는 피리다지논유도체 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU198696B (en) * | 1987-01-20 | 1989-11-28 | Nissan Chemical Ind Ltd | Process for producing 3/2h/-pyridazinon derivatives and pharmaceutical compositions containing them as active components |
| JPH02256668A (ja) * | 1988-12-20 | 1990-10-17 | Nissan Chem Ind Ltd | ピリダジノン誘導体 |
| HU208124B (en) * | 1990-04-25 | 1993-08-30 | Nissan Chemical Ind Ltd | Process for producing pyridazinone derivatives and pharmaceutical compositions comprising such derivatives as active ingredient |
| JPH05112454A (ja) * | 1991-10-18 | 1993-05-07 | Nissan Chem Ind Ltd | 抗血小板剤 |
-
1994
- 1994-12-13 NZ NZ270130A patent/NZ270130A/en unknown
- 1994-12-13 TW TW083111592A patent/TW326041B/zh active
- 1994-12-14 AU AU80413/94A patent/AU675889B2/en not_active Ceased
- 1994-12-15 DE DE69406763T patent/DE69406763T2/de not_active Expired - Fee Related
- 1994-12-15 KR KR1019940034485A patent/KR950017967A/ko not_active Withdrawn
- 1994-12-15 AT AT94119888T patent/ATE160144T1/de not_active IP Right Cessation
- 1994-12-15 DK DK94119888.9T patent/DK0658555T3/da active
- 1994-12-15 CN CN94113479A patent/CN1109878A/zh active Pending
- 1994-12-15 EP EP94119888A patent/EP0658555B1/de not_active Expired - Lifetime
- 1994-12-15 US US08/356,510 patent/US5604226A/en not_active Expired - Fee Related
- 1994-12-15 ES ES94119888T patent/ES2112470T3/es not_active Expired - Lifetime
- 1994-12-15 CA CA002138224A patent/CA2138224A1/en not_active Abandoned
-
1998
- 1998-01-28 GR GR980400176T patent/GR3026006T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2112470T3 (es) | 1998-04-01 |
| GR3026006T3 (en) | 1998-04-30 |
| DE69406763T2 (de) | 1998-03-12 |
| KR950017967A (ko) | 1995-07-22 |
| AU675889B2 (en) | 1997-02-20 |
| AU8041394A (en) | 1995-06-22 |
| EP0658555B1 (de) | 1997-11-12 |
| DK0658555T3 (da) | 1997-12-22 |
| CA2138224A1 (en) | 1995-06-17 |
| NZ270130A (en) | 1995-12-21 |
| EP0658555A1 (de) | 1995-06-21 |
| CN1109878A (zh) | 1995-10-11 |
| TW326041B (en) | 1998-02-01 |
| US5604226A (en) | 1997-02-18 |
| DE69406763D1 (de) | 1997-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |