ATE161531T1 - Acridine-1,8-dionderivate als therapeutisches mittel - Google Patents
Acridine-1,8-dionderivate als therapeutisches mittelInfo
- Publication number
- ATE161531T1 ATE161531T1 AT92309567T AT92309567T ATE161531T1 AT E161531 T1 ATE161531 T1 AT E161531T1 AT 92309567 T AT92309567 T AT 92309567T AT 92309567 T AT92309567 T AT 92309567T AT E161531 T1 ATE161531 T1 AT E161531T1
- Authority
- AT
- Austria
- Prior art keywords
- acridine
- therapeutic agent
- dione derivatives
- dione
- derivatives
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919122305A GB9122305D0 (en) | 1991-10-21 | 1991-10-21 | Therapeutic agents |
| GB929213548A GB9213548D0 (en) | 1992-06-25 | 1992-06-25 | Therapeutic method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE161531T1 true ATE161531T1 (de) | 1998-01-15 |
Family
ID=26299723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92309567T ATE161531T1 (de) | 1991-10-21 | 1992-10-20 | Acridine-1,8-dionderivate als therapeutisches mittel |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US5340819A (de) |
| EP (1) | EP0539154B1 (de) |
| JP (1) | JP3285963B2 (de) |
| AT (1) | ATE161531T1 (de) |
| CA (1) | CA2080949A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455253A (en) * | 1992-10-20 | 1995-10-03 | Zeneca Limited | Heterocyclic derivatives |
| GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
| JP3348230B2 (ja) | 1995-03-03 | 2002-11-20 | アルゴス ファーマシューティカル コーポレーション | 尿失禁の治療用のデキシトルメトルファン又はデキシトルオルファンの使用 |
| GB9707695D0 (en) * | 1996-08-07 | 1997-06-04 | Hoffmann La Roche | Tricyclic dione derivatives |
| US7030096B1 (en) * | 1997-02-13 | 2006-04-18 | Albert Einstein College Of Medicine Of Yeshiva University | Method of enhancing relaxation of penile smooth muscle by introduction of DNA encoding maxi-K potassium channel protein |
| US6593335B1 (en) | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
| US6265417B1 (en) | 1997-12-18 | 2001-07-24 | Abbott Laboratories | Potassium channel openers |
| JP2002508354A (ja) * | 1997-12-18 | 2002-03-19 | アボット・ラボラトリーズ | カリウムチャンネル開放剤 |
| US6642222B2 (en) | 1998-10-28 | 2003-11-04 | Abbott Laboratories | Pyrano, piperidino, and thiopyrano compounds and methods of use |
| US6191140B1 (en) * | 1998-10-28 | 2001-02-20 | Abbott Laboratories | Pyrano, piperidino, and thiopyrano compounds and methods of use |
| JP2002528452A (ja) * | 1998-10-28 | 2002-09-03 | アボット・ラボラトリーズ | ジヒドロピリジン化合物および使用方法 |
| US6518279B2 (en) * | 1999-03-04 | 2003-02-11 | Abbott Laboratories | Cyclopentanone dihydropyridine compounds useful as potassium channel openers |
| WO2001083480A2 (en) * | 2000-05-02 | 2001-11-08 | Abbott Laboratories | Dihydropyridine compounds and methods of use |
| DE602007003697D1 (de) | 2006-02-10 | 2010-01-21 | Janssen Pharmaceutica Nv | Ffner |
| CN102219740B (zh) * | 2010-09-10 | 2013-02-13 | 长春华洋高科技有限公司 | 1，2，3，4，5，6，7，8-八氢-9-苯乙酰胺基吖啶及制备方法和药用用途 |
| US11939316B1 (en) | 2023-11-06 | 2024-03-26 | King Faisal University | 9-(6-flouro-2-hydroxyouinolin-3-yl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexhydroacridine-1,8(2h,5h)-dione as an antimicrobial compound |
| US11970478B1 (en) | 2023-11-16 | 2024-04-30 | King Faisal University | 9-(2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3454577A (en) * | 1965-11-09 | 1969-07-08 | Hoffmann La Roche | 4-(1,2,3,4,5,6,7,8 - octahydro - 1,8 - dioxo-9-acridanyl) - benzenesulfonamide and derivatives |
| DE2003148A1 (de) * | 1970-01-24 | 1971-07-29 | Bayer Ag | Neue 1,4-Dihydropyridinderivate |
| DE2018738A1 (en) * | 1970-04-18 | 1971-10-28 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Hydrogenated pyridines, quinolines andacridi |
| US4021434A (en) * | 1972-01-22 | 1977-05-03 | Yamanouchi Pharmaceutical Co., Ltd. | Sodium β-[2,6-dimethyl-3,5-bis(ethoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-1-yl]ethyl sulfate |
| DE2242106A1 (de) * | 1972-08-26 | 1974-03-21 | Agfa Gevaert Ag | Lichtempfindliches photographisches material |
| JPS5234631A (en) * | 1975-09-12 | 1977-03-16 | Hitachi Ltd | Power source abnormality detection circuit |
| DE2718130C2 (de) * | 1977-04-23 | 1979-05-17 | Du Pont De Nemours (Deutschland) Gmbh, 4000 Duesseldorf | lichtempfindliches Aufzeichnungsmaterial |
| US4546186A (en) * | 1983-12-14 | 1985-10-08 | American Home Products Corporation | 1,4,5,6,7,8-Hexahydro-2-methyl-5-oxo-4-(2-thiazolyl)-3-quinoline carboxylic acid 2-methyl(phenylmethyl)amino ethyl ester and pharmaceutically acceptable salts |
| US5238390A (en) * | 1990-10-19 | 1993-08-24 | Edward S. Robbins, III | Blow-molding apparatus for fabricating hollow articles from an open-ended tubular body of thermoplastic material |
| GB9214120D0 (en) * | 1991-07-25 | 1992-08-12 | Ici Plc | Therapeutic amides |
| GB9220570D0 (en) | 1991-10-21 | 1992-11-11 | Ici Plc | Therapeutic agent |
-
1992
- 1992-10-20 JP JP28187292A patent/JP3285963B2/ja not_active Expired - Fee Related
- 1992-10-20 AT AT92309567T patent/ATE161531T1/de not_active IP Right Cessation
- 1992-10-20 EP EP92309567A patent/EP0539154B1/de not_active Expired - Lifetime
- 1992-10-20 US US07/963,863 patent/US5340819A/en not_active Expired - Lifetime
- 1992-10-20 CA CA002080949A patent/CA2080949A1/en not_active Abandoned
-
1994
- 1994-02-08 US US08/193,346 patent/US5484792A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0539154B1 (de) | 1997-12-29 |
| CA2080949A1 (en) | 1993-04-22 |
| EP0539154A1 (de) | 1993-04-28 |
| JPH05213888A (ja) | 1993-08-24 |
| US5340819A (en) | 1994-08-23 |
| JP3285963B2 (ja) | 2002-05-27 |
| US5484792A (en) | 1996-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |