ATE164591T1 - Herstellung und durchmusterung von hochgradig diversen peptidbanken hinschtlich bindungsaktivität - Google Patents

Herstellung und durchmusterung von hochgradig diversen peptidbanken hinschtlich bindungsaktivität

Info

Publication number
ATE164591T1
ATE164591T1 AT94109577T AT94109577T ATE164591T1 AT E164591 T1 ATE164591 T1 AT E164591T1 AT 94109577 T AT94109577 T AT 94109577T AT 94109577 T AT94109577 T AT 94109577T AT E164591 T1 ATE164591 T1 AT E164591T1
Authority
AT
Austria
Prior art keywords
screening
preparation
binding activity
highly diverse
diverse peptide
Prior art date
Application number
AT94109577T
Other languages
English (en)
Inventor
Eran Hadas
Vered Hornik
Original Assignee
Interpharm Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interpharm Lab Ltd filed Critical Interpharm Lab Ltd
Application granted granted Critical
Publication of ATE164591T1 publication Critical patent/ATE164591T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94109577T 1993-06-22 1994-06-21 Herstellung und durchmusterung von hochgradig diversen peptidbanken hinschtlich bindungsaktivität ATE164591T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL106106A IL106106A0 (en) 1993-06-22 1993-06-22 Library of polymeric molecules and its preparation

Publications (1)

Publication Number Publication Date
ATE164591T1 true ATE164591T1 (de) 1998-04-15

Family

ID=11064976

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94109577T ATE164591T1 (de) 1993-06-22 1994-06-21 Herstellung und durchmusterung von hochgradig diversen peptidbanken hinschtlich bindungsaktivität

Country Status (10)

Country Link
EP (1) EP0639584B1 (de)
JP (1) JPH07194382A (de)
AT (1) ATE164591T1 (de)
AU (1) AU678460B2 (de)
CA (1) CA2126359A1 (de)
DE (1) DE69409312T2 (de)
DK (1) DK0639584T3 (de)
ES (1) ES2114633T3 (de)
IL (1) IL106106A0 (de)
ZA (1) ZA944474B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0705279T3 (da) * 1993-05-27 2003-06-10 Selectide Corp Topologisk adskilte, kodende fastfase-biblioteker
US5840485A (en) * 1993-05-27 1998-11-24 Selectide Corporation Topologically segregated, encoded solid phase libraries
WO1995011998A1 (en) * 1993-10-26 1995-05-04 United Biomedical, Inc. Structured synthetic antigen libraries as diagnostics, vaccines and therapeutics
US6743892B1 (en) 1995-09-11 2004-06-01 La Jolla Cancer Research Foundation Molecules that home to a selected organ in vivo
JP3900305B2 (ja) * 1995-09-11 2007-04-04 ザ バーナム インスティテュート インビボにおいて選択された器官または組織に帰巣する分子および同分子を同定する方法
AU728668B2 (en) * 1995-09-11 2001-01-18 La Jolla Cancer Research Foundation Molecules that home to a selected organ or tissue in vivo and methods of identifying same
US6068829A (en) * 1995-09-11 2000-05-30 The Burnham Institute Method of identifying molecules that home to a selected organ in vivo
EP0868427B1 (de) * 1995-12-18 2003-05-14 Praecis Pharmaceuticals Incorporated Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden
US6277583B1 (en) 1996-02-07 2001-08-21 Conjuchem, Inc. Affinity labeling libraries and applications thereof
US6576239B1 (en) 1996-09-10 2003-06-10 The Burnham Institute Angiogenic homing molecules and conjugates derived therefrom
US6232287B1 (en) 1998-03-13 2001-05-15 The Burnham Institute Molecules that home to various selected organs or tissues
HUP0103260A3 (en) * 1998-03-23 2002-03-28 Harvard College Peptidomimetic compounds and process for their synthesis
JP2002516983A (ja) * 1998-03-30 2002-06-11 ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア 核受容体活性を調節するための方法及び化合物
PL204359B1 (pl) * 1998-08-28 2010-01-29 Myelos Corp Cykliczne peptydy, zawierająca je kompozycja farmaceutyczna i ich zastosowania
WO2001062772A2 (en) * 2000-02-23 2001-08-30 Xenoport, Inc. Self-encoded combinatorial synthesis of compound multiplets
DE10012962B4 (de) * 2000-03-16 2005-08-04 Peter Prof. Dr. Bäuerle Verfahren zur Parallelsynthese von mindestens zwei Cumarinderivaten sowie substituierte Cumarinderivate und Arylboronsäurepropandiolester
US7452964B2 (en) 2001-09-07 2008-11-18 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides against placenta and adipose tissues
US20040170955A1 (en) 2000-09-08 2004-09-02 Wadih Arap Human and mouse targeting peptides identified by phage display
US7420030B2 (en) 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
ES2300379T3 (es) 2000-12-23 2008-06-16 Novartis Vaccines And Diagnostics, Inc. Procedimiento de deteccion selectiva de transfeccion de oligonucleotidos.
US7544767B2 (en) 2002-04-05 2009-06-09 Burnham Institute For Medical Research HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells
EP1521841B1 (de) * 2002-07-11 2010-04-14 The American National Red Cross Verfahren zur identifizierung einzelner aktiver einheiten aus komplexen gemischen
GB0305448D0 (en) * 2003-03-10 2003-04-16 Tcp Innovations Ltd Immunoassay
EP1734367A1 (de) * 2005-06-14 2006-12-20 Cellzome Ag Verfahren zum Auffinden von neuen Verbindungen, die mit einem Enzym in Wechselwirkung treten
EP2456910B1 (de) * 2009-07-22 2016-05-04 Agency For Science, Technology And Research Differenzierung von isobaren aminosäuren und anderen spezies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2124087C (en) * 1991-11-22 2002-10-01 James L. Winkler Combinatorial strategies for polymer synthesis
KR100310939B1 (ko) * 1992-10-01 2002-06-20 추후제출 태그로암호화한복합조합화학라이브러리

Also Published As

Publication number Publication date
ES2114633T3 (es) 1998-06-01
CA2126359A1 (en) 1994-12-23
DE69409312T2 (de) 1998-10-01
ZA944474B (en) 1995-02-14
DE69409312D1 (de) 1998-05-07
JPH07194382A (ja) 1995-08-01
DK0639584T3 (da) 1998-05-11
EP0639584B1 (de) 1998-04-01
IL106106A0 (en) 1993-10-20
AU6487394A (en) 1995-01-05
AU678460B2 (en) 1997-05-29
EP0639584A1 (de) 1995-02-22

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee