ATE164885T1 - Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten - Google Patents

Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten

Info

Publication number
ATE164885T1
ATE164885T1 AT87901222T AT87901222T ATE164885T1 AT E164885 T1 ATE164885 T1 AT E164885T1 AT 87901222 T AT87901222 T AT 87901222T AT 87901222 T AT87901222 T AT 87901222T AT E164885 T1 ATE164885 T1 AT E164885T1
Authority
AT
Austria
Prior art keywords
herpes viruses
weakened
foreign dna
amino acid
acid sequences
Prior art date
Application number
AT87901222T
Other languages
English (en)
Inventor
Mark D Cochran
Meng-Fu Shih
William P Macconnel
Richard D Macdonald
Original Assignee
Syntro Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/823,102 external-priority patent/US5068192A/en
Application filed by Syntro Corp filed Critical Syntro Corp
Application granted granted Critical
Publication of ATE164885T1 publication Critical patent/ATE164885T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16741—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16761—Methods of inactivation or attenuation
    • C12N2710/16762—Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT87901222T 1986-01-27 1987-01-23 Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten ATE164885T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/823,102 US5068192A (en) 1986-01-27 1986-01-27 Attenuated pseudorabies virus which includes foreign DNA encoding an amino acid sequence
US88714086A 1986-07-17 1986-07-17
US90288786A 1986-09-02 1986-09-02
US93310786A 1986-11-20 1986-11-20

Publications (1)

Publication Number Publication Date
ATE164885T1 true ATE164885T1 (de) 1998-04-15

Family

ID=27505864

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97103457T ATE342996T1 (de) 1986-01-27 1987-01-23 Attenuierte herpesviren, herpesviren die eine aminosäuresequenz kodierende fremde dna enthalten,und diese enthaltende impfstoffe
AT87901222T ATE164885T1 (de) 1986-01-27 1987-01-23 Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT97103457T ATE342996T1 (de) 1986-01-27 1987-01-23 Attenuierte herpesviren, herpesviren die eine aminosäuresequenz kodierende fremde dna enthalten,und diese enthaltende impfstoffe

Country Status (5)

Country Link
EP (1) EP0794257B1 (de)
AT (2) ATE342996T1 (de)
CA (1) CA1339468C (de)
DE (3) DE3752389T2 (de)
LU (1) LU91303I2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0965639A1 (de) * 1998-06-05 1999-12-22 Boehringer Ingelheim Vetmedica Gmbh Attenuierte Pestiviren
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
UY31930A (es) 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
EP2629794B1 (de) 2010-10-18 2017-06-07 Intervet International B.V. Durch den truthahn-herpesvirus vektorisierter impfstoff gegen vogelgrippe bei geflügel
RU2624037C2 (ru) 2011-10-21 2017-06-30 Интервет Интернэшнл Б.В. Конструкции рекомбинантного непатогенного вируса болезни марека, кодирующие антигены вируса инфекционного ларинготрахеита и вируса болезни ньюкасла
WO2013057235A1 (en) 2011-10-21 2013-04-25 Intervet International B.V. Recombinant nonpathogenic mdv vector providing multivalent immunity
MA58717A1 (fr) 2020-06-17 2023-06-28 Boehringer Ingelheim Vetmedica Gmbh Vecteurs hvt recombinants exprimant l'hémagglutinine de la grippe et compositions immunogènes, et leur fabrication et leurs utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000528A1 (en) * 1984-07-05 1986-01-30 Genex Corporation Cloned gene and method for making and using the same

Also Published As

Publication number Publication date
DE122007000004I1 (de) 2007-05-24
DE3752182T2 (de) 1998-08-06
DE3752182D1 (de) 1998-05-14
EP0794257B1 (de) 2006-10-18
LU91303I2 (fr) 2007-03-12
ATE342996T1 (de) 2006-11-15
EP0794257A1 (de) 1997-09-10
DE3752389T2 (de) 2007-06-14
CA1339468C (en) 1997-09-23
DE3752389D1 (de) 2006-11-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
RZN Patent revoked